Lab Medicine Rounds

Reversal of DOACs: Making critical advancements


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Timestamps:

00:00 Intro

00:43 Why is it important for physicians to understand about the reversal of these direct oral anticoagulants?

03:09 The complications or the bleed rate was a lot less, with these direct oral anticoagulants?

03:57 Although there is less severe bleeding, there was a concern by patients and physicians about, if it is severe, what is the plan? 

04:51 What have we learned new? Are we learning more about what patient population to use them in, as well as the plans to reverse them?

06:10 Can you elaborate a little bit about the idea for weekly monitoring for INR, why is it a big deal? 

7:44 Could you give us an example of where it wouldn’t be ideal to do home INR monitoring for a given patient?

09:06 Are there updates to what the reversal plans are, and how have they changed recently?

12:34 Are there still some challenges that remain for reversing these direct oral anticoagulants?

19:54 What do you think the future looks like for anticoagulant reversal? 

23:47 Outro

Resources:

https://pubmed.ncbi.nlm.nih.gov/30916798/

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Lab Medicine RoundsBy Mayo Clinic Laboratories

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