Science Friday

New Device Helps People With Paralysis Walk Again

Spinal cord injuries are notoriously difficult to treat, especially for those who have been paralyzed for several years.

Now, researchers have developed a new implant that is able to reverse paralysis in patients with complete spinal cord injuries. The device uses specially designed electrodes, which bring the brain back into communication with the patient’s lower body. The findings were recently published in the academic journal Nature Medicine.

Ira talks with the study’s co-authors, Jocelyne Bloch, a neurosurgeon at Lausanne University Hospital, and Grégoire Courtine, professor of neuroscience at the Swiss Federal Institute of Technology, based in Lausanne, Switzerland.

A new generation of COVID-19 vaccines are being developed and distributed around the world. They’re called recombinant-protein vaccines. But the tech is actually not at all new. In fact, It’s been used to produce hepatitis C and pertussis vaccines for decades.

These protein-based vaccines have an edge over mRNA vaccines in a few ways. They’re just as effective, cheaper and simpler to manufacture, and easier to distribute. So why, two years into the pandemic, have they just started gaining traction? And can recombinant-protein vaccines help close the global coronavirus vaccination gap?

Ira discusses these developments with Dr. Maria Elena Bottazzi, the co-creator of Corbevax, a patent-free protein-based vaccine, for which she was recently nominated for the Nobel Peace Prize. She’s also the co-director of the Center for Vaccine Development at Texas Children’s Hospital, and a professor at the Baylor College of Medicine, based in Houston, Texas.

Cuba was able to quickly produce five coronavirus vaccines, thanks to the island’s robust biotech industry. For decades, Cuba has produced its own home-grown vaccines and distributed them to neighboring countries.

But sanctions and political dynamics have complicated Cuba’s ability to distribute their COVID-19 vaccines with the world.

Ira talks with Helen Yaffe, senior lecturer of economic and social history at Glasgow University, and author of We Are Cuba! How a Revolutionary People Have Survived in a Post-Soviet World.

One of the most famous films of undersea explorer Jacques Cousteau was titled The Silent World. But when you actually stop and listen to the fishes, the world beneath the waves is a surprisingly noisy place.

In a recent study published in the journal Ichthyology & Herpetology, researchers report that as many of two-thirds of the ray-finned fish families either are known to make sounds, or at least have the physical capability to do so.

Some fish use specialized muscles around their buoyancy-modulating swim bladders to make noise. Others might blow bubbles out their mouths, or, in the case of herring, out their rear ends, producing “fish farts.” Still other species use ridges on their bodies to make noises similar to the way crickets do, grind their teeth, or snap a tendon to sound off. The noises serve a variety of purposes, from calling for a mate to warning off an adversary.

Aaron Rice, principal ecologist in the K. Lisa Yang Center for Conservation Bioacoustics at the Cornell Lab of Ornithology in Ithaca, walks Ira through some of the unusual sounds produced by known fish around the world—and some mystery noises that they know are produced by fish, but have yet to identify.

Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that’s keeping you up at night? Call us: 877-472-4374

Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Spinal cord injuries are notoriously difficult to treat, especially for those who have been paralyzed for several years.

Now, researchers have developed a new implant that is able to reverse paralysis in patients with complete spinal cord injuries. The device uses specially designed electrodes, which bring the brain back into communication with the patient’s lower body. The findings were recently published in the academic journal Nature Medicine.

Ira talks with the study’s co-authors, Jocelyne Bloch, a neurosurgeon at Lausanne University Hospital, and Grégoire Courtine, professor of neuroscience at the Swiss Federal Institute of Technology, based in Lausanne, Switzerland.

A new generation of COVID-19 vaccines are being developed and distributed around the world. They’re called recombinant-protein vaccines. But the tech is actually not at all new. In fact, It’s been used to produce hepatitis C and pertussis vaccines for decades.

These protein-based vaccines have an edge over mRNA vaccines in a few ways. They’re just as effective, cheaper and simpler to manufacture, and easier to distribute. So why, two years into the pandemic, have they just started gaining traction? And can recombinant-protein vaccines help close the global coronavirus vaccination gap?

Ira discusses these developments with Dr. Maria Elena Bottazzi, the co-creator of Corbevax, a patent-free protein-based vaccine, for which she was recently nominated for the Nobel Peace Prize. She’s also the co-director of the Center for Vaccine Development at Texas Children’s Hospital, and a professor at the Baylor College of Medicine, based in Houston, Texas.

Cuba was able to quickly produce five coronavirus vaccines, thanks to the island’s robust biotech industry. For decades, Cuba has produced its own home-grown vaccines and distributed them to neighboring countries.

But sanctions and political dynamics have complicated Cuba’s ability to distribute their COVID-19 vaccines with the world.

Ira talks with Helen Yaffe, senior lecturer of economic and social history at Glasgow University, and author of We Are Cuba! How a Revolutionary People Have Survived in a Post-Soviet World.

One of the most famous films of undersea explorer Jacques Cousteau was titled The Silent World. But when you actually stop and listen to the fishes, the world beneath the waves is a surprisingly noisy place.

In a recent study published in the journal Ichthyology & Herpetology, researchers report that as many of two-thirds of the ray-finned fish families either are known to make sounds, or at least have the physical capability to do so.

Some fish use specialized muscles around their buoyancy-modulating swim bladders to make noise. Others might blow bubbles out their mouths, or, in the case of herring, out their rear ends, producing “fish farts.” Still other species use ridges on their bodies to make noises similar to the way crickets do, grind their teeth, or snap a tendon to sound off. The noises serve a variety of purposes, from calling for a mate to warning off an adversary.

Aaron Rice, principal ecologist in the K. Lisa Yang Center for Conservation Bioacoustics at the Cornell Lab of Ornithology in Ithaca, walks Ira through some of the unusual sounds produced by known fish around the world—and some mystery noises that they know are produced by fish, but have yet to identify.

Third Person Cured From HIV, Thanks To Umbilical Cord Stem Cells

The third person ever, and the first woman, has been cured of the HIV virus, thanks to a stem cell transplant using umbilical cord blood. While the invasive, risky bone marrow transplant process may not prove the answer for large numbers of people, the use of cord blood may open up pathways to new treatment options for a wider variety of people than the adult stem cells used to cure the two previous patients.

Vox staff writer Umair Irfan explains why. Plus how President Biden is using executive orders for decarbonizing new parts of the economy, new research on the climate origins of the mega-drought in the American West, a prediction for even more rapidly rising sea levels from NOAA, and how orangutans—some of them at least—might be able to use tools.

When a public health crisis strikes, a natural instinct is to turn to a strong leader. The COVID-19 pandemic is a prime example: We want someone who can calm our fears, tell us what to expect, and what steps we can take to make things better. But leadership does not happen overnight—and it will take a brave person to step into the shoes that guide the country through the next stage of the pandemic.

Dr. David Satcher is used to adversity. Born into poverty in Anniston, Alabama, Satcher contracted whooping cough at two years old. The town’s only Black doctor, Dr. Jackson, treated Satcher, but did not expect him to live. Overcoming this illness launched him into a lifetime of public health work, with an emphasis on health equity.

Satcher speaks to Ira about his work as former assistant secretary for health, surgeon general of the U.S., and director of the Centers for Disease Control under Presidents Bill Clinton and George W. Bush. They also discuss his leadership work at the Morehouse School of Medicine, and his advice for getting the country towards a more equitable healthcare system.

The promise of a human-made, sustained, controlled nuclear fusion reaction has always seemed to be “just a few decades away.” But now recent results from JET, the Joint European Torus experiment, have researchers hopeful that practical fusion may indeed be possible as soon as 2035.

In the experiment, a high-temperature plasma made of equal parts deuterium and tritium was confined in a magnetic containment vessel known as a tokamak. The run produced 59 megajoules of energy over a fusion “pulse” of five seconds, considerably longer than previous attempts. While the experiment did not produce more energy than it took to produce the extreme conditions needed to induce fusion, researchers took the run as a proof of concept that an upcoming reactor called ITER should be successful.

Alain Bécoulet, head of the engineering domain for the ITER project and author of the upcoming book Star Power: ITER and the International Quest for Fusion Energy joins Ira to discuss the recent advance at JET and the prospects for producing a sustained, controlled nuclear fusion reaction—what Bécoulet calls mastering a small piece of the sun.

Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that’s keeping you up at night? Call us: 877-472-4374

Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

The third person ever, and the first woman, has been cured of the HIV virus, thanks to a stem cell transplant using umbilical cord blood. While the invasive, risky bone marrow transplant process may not prove the answer for large numbers of people, the use of cord blood may open up pathways to new treatment options for a wider variety of people than the adult stem cells used to cure the two previous patients.

Vox staff writer Umair Irfan explains why. Plus how President Biden is using executive orders for decarbonizing new parts of the economy, new research on the climate origins of the mega-drought in the American West, a prediction for even more rapidly rising sea levels from NOAA, and how orangutans—some of them at least—might be able to use tools.

When a public health crisis strikes, a natural instinct is to turn to a strong leader. The COVID-19 pandemic is a prime example: We want someone who can calm our fears, tell us what to expect, and what steps we can take to make things better. But leadership does not happen overnight—and it will take a brave person to step into the shoes that guide the country through the next stage of the pandemic.

Dr. David Satcher is used to adversity. Born into poverty in Anniston, Alabama, Satcher contracted whooping cough at two years old. The town’s only Black doctor, Dr. Jackson, treated Satcher, but did not expect him to live. Overcoming this illness launched him into a lifetime of public health work, with an emphasis on health equity.

Satcher speaks to Ira about his work as former assistant secretary for health, surgeon general of the U.S., and director of the Centers for Disease Control under Presidents Bill Clinton and George W. Bush. They also discuss his leadership work at the Morehouse School of Medicine, and his advice for getting the country towards a more equitable healthcare system.

The promise of a human-made, sustained, controlled nuclear fusion reaction has always seemed to be “just a few decades away.” But now recent results from JET, the Joint European Torus experiment, have researchers hopeful that practical fusion may indeed be possible as soon as 2035.

In the experiment, a high-temperature plasma made of equal parts deuterium and tritium was confined in a magnetic containment vessel known as a tokamak. The run produced 59 megajoules of energy over a fusion “pulse” of five seconds, considerably longer than previous attempts. While the experiment did not produce more energy than it took to produce the extreme conditions needed to induce fusion, researchers took the run as a proof of concept that an upcoming reactor called ITER should be successful.

Alain Bécoulet, head of the engineering domain for the ITER project and author of the upcoming book Star Power: ITER and the International Quest for Fusion Energy joins Ira to discuss the recent advance at JET and the prospects for producing a sustained, controlled nuclear fusion reaction—what Bécoulet calls mastering a small piece of the sun.

How Grief Rewires The Brain

Being a human can be a wonderful thing. We’re social creatures, craving strong bonds with family and friends. Those relationships can be the most rewarding parts of life.

But having strong relationships also means the possibility of experiencing loss. Grief is one of the hardest things people go through in life. Those who have lost a loved one know the feeling of overwhelming sadness and heartache that seems to well up from the very depths of the body.

To understand why we feel the way we do when we grieve, the logical place to turn is to the source of our emotions: the brain. A new book explores the neuroscience behind this profound human experience.

Ira speaks to Mary-Frances O’Connor, author of The Grieving Brain: The Surprising Science of How We Learn from Love and Loss, a neuroscientist, about adjusting to life after loss.

Two cancer patients treated with gene therapy a decade ago are still in remission. Thousands of patients have undergone this type of immunotherapy, called CAR-T Cell therapy, since then. But these are the first patients that doctors say have been cured by the treatment. The findings were recently published in the academic journal Nature.

Ira talks to Dr. Carl June, co-author of the study, and director of the Center for Cellular Immunotherapies, at the University of Pennsylvania in Philadelphia.

Team USA’s Alpine Ski Team is wearing custom-designed heated shorts to stay warm on the freezing slopes at the Beijing Olympics. But these aren’t your average shorts. They use a lithium-ion battery, and the thread they’re sewn with serves as the heat conductor.

Ira talks with Josh Daniel and Lauren Samuels, graduate students at the University of Oregon’s sports product management program, who came up with the cutting-edge design.

Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that’s keeping you up at night? Call us: 877-472-4374

Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Being a human can be a wonderful thing. We’re social creatures, craving strong bonds with family and friends. Those relationships can be the most rewarding parts of life.

But having strong relationships also means the possibility of experiencing loss. Grief is one of the hardest things people go through in life. Those who have lost a loved one know the feeling of overwhelming sadness and heartache that seems to well up from the very depths of the body.

To understand why we feel the way we do when we grieve, the logical place to turn is to the source of our emotions: the brain. A new book explores the neuroscience behind this profound human experience.

Ira speaks to Mary-Frances O’Connor, author of The Grieving Brain: The Surprising Science of How We Learn from Love and Loss, a neuroscientist, about adjusting to life after loss.

Two cancer patients treated with gene therapy a decade ago are still in remission. Thousands of patients have undergone this type of immunotherapy, called CAR-T Cell therapy, since then. But these are the first patients that doctors say have been cured by the treatment. The findings were recently published in the academic journal Nature.

Ira talks to Dr. Carl June, co-author of the study, and director of the Center for Cellular Immunotherapies, at the University of Pennsylvania in Philadelphia.

Team USA’s Alpine Ski Team is wearing custom-designed heated shorts to stay warm on the freezing slopes at the Beijing Olympics. But these aren’t your average shorts. They use a lithium-ion battery, and the thread they’re sewn with serves as the heat conductor.

Ira talks with Josh Daniel and Lauren Samuels, graduate students at the University of Oregon’s sports product management program, who came up with the cutting-edge design.

An Abrupt Departure For Biden’s Science Adviser

This week, Eric Lander, the Presidential science advisor and head of the Office of Science and Technology Policy, resigned following an investigation into bullying behavior towards his subordinates. In an apology, Lander acknowledged being “disrespectful and demeaning” towards staff.

Lander, a mathematician and genomics researcher, was previously the head of the Broad Institute at Harvard and MIT. Nsikan Akpan, health and science editor for WNYC Radio in New York, joins Ira to discuss the resignation and what it might mean for the president’s science policy initiatives.

They also talk about other stories from the week in science, including an advance in fusion research in Europe, concerns over the increasing saltiness of Lake Michigan, and the question of whether sequestering urine from the sewage stream might have environmental advantages.

Late last year, two new drugs joined the lineup of options for high-risk patients who may need extra help fighting COVID-19: Merck’s pill molnupiravir, and Pfizer’s pill Paxlovid.

The two pills join remdesivir, an infusion-only drug, as antiviral compounds that attack the SARS-CoV2 virus in different ways. But how exactly do they work, how well do they work, and what makes them complicated to use in real life?

Ira talks to virologists Ran Swanstrom and Adam Lauring about the fundamentals of antiviral drugs, concerns about molnupiravir’s method of mutating the virus to death, and the long drug interaction list for Paxlovid. Plus, why timing is a critical issue for getting drugs to patients.

Each generation has had science communicators who brought a sometimes stuffy, siloed subject into homes, inspiring minds young and old. Scientists like Don Herbert, Carl Sagan, and Bill Nye are classic examples. But our modern age of social media has brought more diverse communicators into the forefront of science communication, including the wild, wonderful world of STEM drag stars.

These are queer folk who mix the flashy fashions of the drag world with science education. Some, like Kyne, use TikTok as a medium to teach concepts like math. Others, like Pattie Gonia, use drag to attract more people to the great outdoors. The accessibility of the internet has made these personalities available to a wide audience.

Kyne and Pattie Gonia join Ira to talk about the magic drag can bring to science education, and why they think the future of SciComm looks more diverse than the past.

Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that’s keeping you up at night? Call us: 877-472-4374

Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

This week, Eric Lander, the Presidential science advisor and head of the Office of Science and Technology Policy, resigned following an investigation into bullying behavior towards his subordinates. In an apology, Lander acknowledged being “disrespectful and demeaning” towards staff.

Lander, a mathematician and genomics researcher, was previously the head of the Broad Institute at Harvard and MIT. Nsikan Akpan, health and science editor for WNYC Radio in New York, joins Ira to discuss the resignation and what it might mean for the president’s science policy initiatives.

They also talk about other stories from the week in science, including an advance in fusion research in Europe, concerns over the increasing saltiness of Lake Michigan, and the question of whether sequestering urine from the sewage stream might have environmental advantages.

Late last year, two new drugs joined the lineup of options for high-risk patients who may need extra help fighting COVID-19: Merck’s pill molnupiravir, and Pfizer’s pill Paxlovid.

The two pills join remdesivir, an infusion-only drug, as antiviral compounds that attack the SARS-CoV2 virus in different ways. But how exactly do they work, how well do they work, and what makes them complicated to use in real life?

Ira talks to virologists Ran Swanstrom and Adam Lauring about the fundamentals of antiviral drugs, concerns about molnupiravir’s method of mutating the virus to death, and the long drug interaction list for Paxlovid. Plus, why timing is a critical issue for getting drugs to patients.

Each generation has had science communicators who brought a sometimes stuffy, siloed subject into homes, inspiring minds young and old. Scientists like Don Herbert, Carl Sagan, and Bill Nye are classic examples. But our modern age of social media has brought more diverse communicators into the forefront of science communication, including the wild, wonderful world of STEM drag stars.

These are queer folk who mix the flashy fashions of the drag world with science education. Some, like Kyne, use TikTok as a medium to teach concepts like math. Others, like Pattie Gonia, use drag to attract more people to the great outdoors. The accessibility of the internet has made these personalities available to a wide audience.

Kyne and Pattie Gonia join Ira to talk about the magic drag can bring to science education, and why they think the future of SciComm looks more diverse than the past.

Phasing Out “Problematic” Plastics

Plastic packaging is just about impossible to avoid. Getting takeout? You’ll likely wind up with a plastic container, or cutlery. Grabbing a coffee? Plastic stirrers and straws are hard to evade. These items are tough to recycle, and most sanitation systems aren’t equipped to process them. That means they go into the trash, or worse, waterways.

Last week, the U.S. Plastics Pact released a much-anticipated list of “Problematic and Unnecessary Materials” that pact members should phase out by 2025. These items include cutlery, straws, and stirrers, as well as materials that include certain chemicals and pigments. The impact could be large: Pact members make up about third of America’s plastic packaging producers. Members include companies that use a lot of packing, like Target, Walmart and Aldi, as well as those that make raw plastic materials.

The goal of the U.S. Plastics Pact is to help make America’s recycling system more circular, where materials in theory could be recycled in perpetuity. But some in the plastics industry say the timeline for phasing out these materials are too fast, or may cause a reliance on more carbon-intensive materials. Joining Ira to break down the potential impact of phasing out these materials is Emily Tipaldo, executive director of the U.S. Plastics Pact, based in Mount Pleasant, South Carolina.

We’ve all had the experience of that uncomfortably sticky feeling of syrup or jam residue on the breakfast table. Or a wad of chewing gum binding our shoe to the sidewalk. But what’s the science behind why some things stick, while other things slip?

Many of the reasons come down to friction, says Laurie Winkless, a physicist and science writer based in New Zealand. Her new book, Sticky: The Secret Science of Surfaces, explores how different materials interact—from the toes of an acrobatic gecko scaling a sheer wall to the molecular magic inside the rapid fusion of super glue.

Winkless joins SciFri’s Charles Bergquist to talk about surface science, and what makes something slippery, including the question of how the famously non-stick Teflon manages to stick to your kitchen frying pan.

Like their brethren east of the Rocky Mountains, the western population of monarch butterflies has been declining steeply since the mid-1990s. Every November, volunteers set out through the mountains of California with one goal in mind: Count those western monarchs as they gather for winter hibernation. Unfortunately, the recent numbers have been bad news. Back in the 1990s, the western population numbered more than a million. But in 2018 and 2019, volunteers only counted about 20,000 and 30,000, respectively. In 2020, the count turned up a mere 2,000 butterflies.

This year, though, the news was good: The 2021 Thanksgiving Count found nearly 250,000 butterflies in winter enclaves throughout California.

How did the population bounce back so dramatically? And is this number a blip on the radar, or the start of better times for the beleaguered butterfly? Ira talks to UC-Davis entomologist Louie Yang about the intricate timing of milkweed and monarchs, and why ecologists remain uncertain about the fate of this charismatic insect.

Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that’s keeping you up at night? Call us: 877-472-4374

Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Plastic packaging is just about impossible to avoid. Getting takeout? You’ll likely wind up with a plastic container, or cutlery. Grabbing a coffee? Plastic stirrers and straws are hard to evade. These items are tough to recycle, and most sanitation systems aren’t equipped to process them. That means they go into the trash, or worse, waterways.

Last week, the U.S. Plastics Pact released a much-anticipated list of “Problematic and Unnecessary Materials” that pact members should phase out by 2025. These items include cutlery, straws, and stirrers, as well as materials that include certain chemicals and pigments. The impact could be large: Pact members make up about third of America’s plastic packaging producers. Members include companies that use a lot of packing, like Target, Walmart and Aldi, as well as those that make raw plastic materials.

The goal of the U.S. Plastics Pact is to help make America’s recycling system more circular, where materials in theory could be recycled in perpetuity. But some in the plastics industry say the timeline for phasing out these materials are too fast, or may cause a reliance on more carbon-intensive materials. Joining Ira to break down the potential impact of phasing out these materials is Emily Tipaldo, executive director of the U.S. Plastics Pact, based in Mount Pleasant, South Carolina.

We’ve all had the experience of that uncomfortably sticky feeling of syrup or jam residue on the breakfast table. Or a wad of chewing gum binding our shoe to the sidewalk. But what’s the science behind why some things stick, while other things slip?

Many of the reasons come down to friction, says Laurie Winkless, a physicist and science writer based in New Zealand. Her new book, Sticky: The Secret Science of Surfaces, explores how different materials interact—from the toes of an acrobatic gecko scaling a sheer wall to the molecular magic inside the rapid fusion of super glue.

Winkless joins SciFri’s Charles Bergquist to talk about surface science, and what makes something slippery, including the question of how the famously non-stick Teflon manages to stick to your kitchen frying pan.

Like their brethren east of the Rocky Mountains, the western population of monarch butterflies has been declining steeply since the mid-1990s. Every November, volunteers set out through the mountains of California with one goal in mind: Count those western monarchs as they gather for winter hibernation. Unfortunately, the recent numbers have been bad news. Back in the 1990s, the western population numbered more than a million. But in 2018 and 2019, volunteers only counted about 20,000 and 30,000, respectively. In 2020, the count turned up a mere 2,000 butterflies.

This year, though, the news was good: The 2021 Thanksgiving Count found nearly 250,000 butterflies in winter enclaves throughout California.

How did the population bounce back so dramatically? And is this number a blip on the radar, or the start of better times for the beleaguered butterfly? Ira talks to UC-Davis entomologist Louie Yang about the intricate timing of milkweed and monarchs, and why ecologists remain uncertain about the fate of this charismatic insect.