The 2023 Nobel Prize in Physiology or Medicine was awarded to Katalin Karikó and Drew Weismann for their contributions to developing the fundamentals that led to life saving mRNA vaccines. Although funding and support were not always assured on their road to the Nobel, Katalin Karikó tells Roland she used these setbacks to drive her towards success.

On the other side of the coin, allegations of scientific misconduct over bold room temperature superconductivity claims. Earlier this year, eleven authors submitted a paper to Nature. Now, eight of them are calling for a retraction. Science journalist Dan Garisto covers the story.

Also this week, NASA Ames researcher Jacob Kegerreis details how Saturn got its rings. Hint: It’s a smashing story.

And, what is the most fear inducing sound in the world? Lions roaring? Gunshots? According to mammals in South Africa it is the human voice. Fear-ecologist Liana Zanette explains.

(Image: Katalin Karikó. Credit: Mark Makela / Getty Images)

What did a 465-million-year-old trilobite eat for dinner? And how can we possibly know? Archaeologist Per Ahlberg has used x-ray to peer into the guts of one ancient scuttling creature and worked out what it what was munching on in its final moments.

From life in ancient earth rocks to potential life in space rocks, mineralogist and astrobiologist Bob Hazen has been training AI to spot signatures of life on Earth. He now hopes to use this tool on space samples.

We also ask experimental particle physicist Jeffrey Hangst how antimatter, the last mystery of the universe, responds to gravity - was Einstein's theory of general relativity right?

And the antiviral Covid medication, Molnupiravir, may be causing the virus to mutate. Theo Sanderson discusses how he figured this out and how concerned we should be.

Presenter: Roland Pease

(Image: Fig. 1: Bohemolichas incola (Barrande, 1872). Credit: Kraft et al)

Storm Daniel devastated the city of Derna in Libya after heavy rainfall broke a dam, causing extreme flooding downstream. The World Weather Attribution (WWA) reports that severe flooding in Libya and across the Mediterranean has been made more likely and more intense due to human induced climate change. WWA scientist Friederike Otto gets into the report.

Back in 2020, NASA’s OSIRIS-REx scooped up rock and dust samples from asteroid Bennu and on Sunday September 24th, 2023 the sample capsule will finally be released 100,000 kilometres above Earth, delivering it to the Great Salk Lake Desert. OSIRIS REx engineer Anjani Polit tells us about the nail-biting return.

Also this week, Dr Peter Hotez warns us about the dangerous and rapid rise of anti-science sentiment in the United States. It’s all in his new book "The Deadly Rise of Anti-Science".

And the remnants of what is thought to be the oldest wooden structure have been found in Zambia. Professor of Archaeology Lawrence Barham talks about the simple structure made by our ancestors almost 500,000 years ago.

Presenter: Roland Pease

(Image: Building collapsed and surrounded by rubble following floods in Derna. Credit: RICARDO GARCIA VILANOVA / Getty Images)

Earlier this week the deadly Mediterranean cyclone, Storm Daniel, swept through the small city of Derna in Libya, collapsing a 50-year-old dam in its wake, and triggering devastating floods which have killed over 5000 people. We speak to atmospheric scientist, Stavros Dafis, about the cyclone’s characteristics and to civil and structural engineer, Lis Bowman, about the dam collapse. Unsurprisingly, it all comes back to climate change.

Far, far from Earth, the James Webb Space Telescope has set its site on the atmosphere of exoplanet K2-18b where the presence of methane and carbon dioxide offer the tantalising possibility of an extraterrestrial Ocean. Astrophysicist Nikku Madhusudhan discusses his exciting results.

And an even less expected presence in space: the ancient remains of our ancestors. Archaeologist Lee Berger has come under fire after sending precious bone samples on a Virgin Galactic space flight. South African archaeologist, Robyn Pickering, expresses the frustration that is on everyone’s mind.

Also expressing their anger, two young climate protesters recently stormed the stage during an orchestral performance at a Swiss music festival. But, to everyone’s surprise, conductor Vladimir Jurowski allowed them to speak to his audience. We hear from the Renovate Switzerland protestors, Anthony and Selina, on their unlikely experience.

Presenter: Roland Pease

(Image: Collapsing buildings and flooded land in the aftermath of the Derna floods. Credit: Anadolu Agency / Getty Images)

In September 2012 Arctic sea ice melted to its minimum ever recorded and the German research ice breaker, Polarstern, ventured deep into the region North of Russia to record findings. It’s now retracing its steps, over a decade later, to observe how things have progressed. Autun Purser and Antje Boethius describe the journey and the importance of documenting developments in the face of climate change.

Some 75 million individuals are believed to live with Long Covid and, in order to treat the plethora of symptoms presented by patients, researchers continue to search for the root source of the condition in the hope of better prescribing broad therapeutics. Akiko Iwasaki, Professor of Immunobiology at Yale University, updates Roland on the working hypotheses.

And one year on from the Hunga Tonga eruption, where a shockwave circled the globe four times, researchers have been able to calculate the speed of the currents in the southern Pacific Ocean. BBC correspondent Jon Amos caught up with Michael Clare to hear how other South Pacific Islands can learn from the most explosive volcanic eruption in 100 years.

Presenter: Roland Pease

Global sea levels are rising more than 3mm per year under current climate conditions. At this rate we are due to hit an alarming 7mm rise per year by the end of the century. If this is not slowed, it could lead to the drowning of essential coastal ecosystems like mangroves and lagoons, professor of environmental science Neil Saintilan tells Science in Action.

The seas are also heating up. We’ve covered the devastating effect of marine heatwaves on vibrant sea life like coral reefs before. But what about the less glamourous bottom-dwelling fish? Ecologist Alexa Fredston has found that they may be more robust than we think.

Also this week, bird virus expert Michelle Wille tells us about the imminent threat of bird flu spreading from South America to Antarctica where hundreds of thousands of sea birds are at risk.

And from one south pole to another, we have an update on how India’s mission on the lunar south pole is going with Lunar and Planetary Institute scientist David Kring.

Image Credit: Marie Hickman

Presenter: Roland Pease

Advances in brain-computer interfaces have allowed patients with paralysis to communicate faster, more accurately and more expressively with direct brain to speech translation. Co-author of an exciting new paper in the field, bioengineer Alex Silva, tells Science in Action about his team’s work with patient Ann.

The world has been following the Indian and Russian race to land on the lunar south pole. Producer Ella Hubber gives a timeline of the events leading up to that historic landing.

Also this week, a new prediction model allows us to better prepare for future extreme weather events. But is this worst-case scenario model scaremongering? Roland talks to author Erich Fischer about the projections.

Image Credit: Noah Berger

Presenter: Roland Pease

Hawaii is still reeling from the devastating fires that consumed Lahaina on the island of Maui last week. Professor of Meteorology from the University of Hawaii, Kevin Hamiliton, joins Science in Action to discuss the factors that make these events more likely across the Hawaiian Islands. Amongst these is climate change.

Also this week we discuss the concerning reports of a sudden spike in methane levels in the Arctic with Xin Lan of the US National Ocean and Atmospheric Administration.

A few weeks ago, we devoted a whole programme to the exciting research on human embryo models made from stem cells. Whilst representing an incredible step for medical research, these raise serious ethical questions. A team of biologists and embryologists have put together a proposal on how to move forward with this ethical quandary, Embryologist Nicolas Rivron tells us more.

And we address the incredible claim of the room temperature super conductor, LK-99, with sceptical materials scientist Michael Fuhrer.

Photo: The Maui town of Lahaina after being destroyed by wildfires

Presenter: Roland Pease

ProMED is one of the most useful scientific tools you’ve never heard of. It’s a global surveillance system of infectious disease outbreaks which is available, for free, to researchers and the public alike. But ISID, the society which runs the platform, claim they have run out of money to support ProMED and will be switching to a subscription service, against the wishes of both users and staff. ProMED editor Marjorie Pollak tells Science in Action about the vital service ProMED has played in pandemic monitoring – including the very first COVID outbreaks - and ISID boss Linda MacKinnon considers what’s next for the platform.

From wildfires in Europe to droughts in Africa, we have covered every kind of environmental disaster across most of the globe in the space of the past few weeks. To complete the distressing bucket list of climate extremes, we’re talking to sea ice expert Caroline Holmes on the concerning forecast for Antarctica.

Despite these terrestrial challenges, NASA is still trying to defend Earth against nearby objects which might hit us from space. The Double Asteroid Redirection Test (DART) was launched at the asteroid Dimorphos back in in November 2021 and, a few weeks ago, the Hubble space telescope observed a swarm of boulders shed by Dimorphos post-impact. Some UK newspapers are concerned about their trajectory, but astronomer Dave Jewitt is here to calm us all down.

Photo: Disinfection Work At Wuhan Huanan Wholesale Seafood Market

Presenter: Roland Pease

Science in Action returns to H5N1, the fast spreading strain of bird flu which has caused devastation in the sky, sea, and land over the last few months, with no end in sight.

Roland visits Skomer Island and the coast of Wales where sea bird colonies are threatened and hundreds of guillemots have washed ashore dead, struck down by bird flu.

We also hear of outbreaks on Finnish fur farms where controversial plans are in progress for culls of wild birds, of mysterious infections of domestic cats in Poland, and bird flu causing brain swelling in grey seals.

Plus, we get an update on efforts to vaccinate condors in California against the disease.

Photo: Dead Guillemot

Presenter: Roland Pease