A multifunctional protein promotes acetylation and activation of the tumor suppressor p53.

Vitamin E promotes dephosphorylation of the kinase Akt to suppress the growth of prostate cancer cells.

Variability in receptor protein abundance affects the sensitivity of T cells to the cytokines IL-2 and IL-7.

Male-type gut microbiota are associated with an increase in testosterone that protects mice from developing type 1 diabetes.

In addition to mediating the transcriptional response to hypoxia, HIF-1α also inhibits proliferation under oxygen-limiting conditions.

An autophagy receptor specifically targets Salmonella for degradation in infected cells.

Vemurafenib induces endoplasmic reticulum stress in melanoma cells.

Identification of inflammatory response regulators sheds light on disease.

B cell receptor clustering determines which kinases are required for signaling.

A phosphatase implicated in autoiummunity modulates the activities of both effector and regulatory T cells.