Steatotic liver disease (SLD) research relies heavily on preclinical models, yet no single model can fully capture the complexity of human disease. In this episode, we explore the new EASL position paper on preclinical SLD models. From MASLD and MetALD to organoids and precision-cut liver slices, we discuss the strengths, limitations, and translational relevance of today's most widely used models. How do we choose the right model, and are we any closer to finding the perfect one?

Based on EASL position paper on preclinical models of steatotic liver disease

Host: Rui Castro (University of Lisbon) 
Speakers: Mathias Heikenwälder (University of Tübingen) and Suchira Gallage (University of Tübingen)

This episode is also available on EASL Campus: https://easlcampus.eu/tltm/episode-11

COI: Rui Castro has no potential conflicts of interest to disclose. Suchira Gallage and Mathias Heikenwälder have disclosed the following potential conflicts of interest: Research collaboration with OrsoBio.