It was one of the greatest medical tragedies of the 20th century.

In 1957, a new wonder drug was launched in Germany. It was marketed as an astonishingly safe sedative. Tragically, this could not have been further from the truth. For this was the drug thalidomide, and it would end up being responsible for around 100,000 miscarriages and disabled children.

This week’s guest, journalist Jennifer Vanderbes,  in a forensic six year investigation has uncovered compelling and shocking new information about warnings that went unheeded, test results that were misrepresented, and uncovered scores of potential victims who have never before been recognised as harmed by the drug.

One of the heroines of this narrative is a dogged and committed FDA reviewer Dr Frances Kelsey, who sceptical of the drug never approved it for US use. However, as Vanderbes reveals in her new book: Wonder Drug The Hidden Victims of America’s Secret Thalidomide Scandal, published by Harper Collins, although the drug was never sold in the states,  the medication was sent out to 1,200 doctors to be used in what were termed clinical trials. These physicians then passed on thalidomide to other colleagues.

But the FDA later described these not as a clinical trials - but a marketing scheme. Which as Jennifer reveals, means, tragically, there are also American babies born with birth defects likely to have been caused by thalidomide.

Had early safety signals been acted on or investigated, thousands of families and babies could have been spared unbelievable heartbreak.

The host of the podcast, Liz Tucker is an award winning medical journalist and former BBC producer and director.  You can follow Liz on Twitter at https://twitter.com/lizctucker and read her Substack newsletter about the podcast at https://liztucker.substack.com

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