Anthony G. Jay, Ph.D., is a biochemist, researcher, bestselling author, and founder of AJ Consulting Company. His research background spans fats, hormones, cholesterol, genetics, epigenetics, stem cells, and infrared light, including work with the U.S. Department of Veterans Affairs and Mayo Clinic. Today, Dr. Jay combines his scientific expertise with public speaking and writing, exploring topics at the intersection of biology, health, and human performance. He and his wife homeschool their five children.

In this episode, Dr. Brian and Dr. Jay talk about…

• (00:00) Intro

• (00:54) Biology and theology

• (03:54) The highest risk factor for heart disease

• (05:43) Plaque reversal

• (08:34) Statins and diabetes risk

• (14:45) LDL and heart disease

• (22:35) Connecting insulin resistance and heart disease

• (25:44) How corruption is keeping harmful medical narratives afloat

• (34:41) Covid coverups

• (37:28) How to avoid bias information in the heart disease space

• (51:40) LPA

• (55:07) ApoB

• (01:01:34) Plaque stabilization and reversal

• (01:06:35) Outro

For more information, please see the links below. Thank you for listening!

Links:

Please consider supporting us on Patreon: https://www.lowcarbmd.com/

Dr. Anthony Jay:

• X: https://x.com/anthonygjay

• Website: https://www.ajconsultingcompany.com

• Sugar Beat (new book!): https://www.amazon.com/Sugar-Beat-CHOLESTEROL-Destroys-REVERSING-ebook/dp/B0H9QN2BL9?ref_=ast_author_mpb

Dr. Brian Lenzkes:

• Website: https://arizonametabolichealth.com/

• Twitter: https://twitter.com/BrianLenzkes?ref_src=twsrc^google|twcamp^serp|twgr^author

Dr. Tro Kalayjian:

• Website: https://toward.health

• Twitter: https://twitter.com/DoctorTro

• IG: https://www.instagram.com/doctortro/

Toward Health App

Join a growing community of individuals who are improving their metabolic health; together.

Get started at your own pace with a self-guided curriculum developed by Dr. Tro and his care team, community chat, weekly meetings, courses, challenges, message boards and more.

Apple: https://apps.apple.com/us/app/doctor-tro/id1588693888

Google: https://play.google.com/store/apps/details?id=uk.co.disciplemedia.doctortro&hl=en_US&gl=US

Learn more: https://toward.health/community/

Dr. Annette Bosworth, known as Dr. Boz, is a physician, educator, and bestselling author who has become a leading voice in metabolic health and therapeutic nutrition. After witnessing firsthand the limitations of conventional approaches to chronic disease, she began exploring the powerful role of nutrition, fasting, and ketosis in improving health. Through her clinical work and popular educational platform, Dr. Boz helps people understand the science behind metabolic health and turn it into practical, sustainable strategies for everyday life.

In this episode, Dr. Brian, Dr. Tro, and Dr. Annette talk about…

• (00:00) Intro
• (02:42) A little bit about Dr. Annette and an overview of the research she is working on
• (11:56) Dr. Annette's research on ketogenic patients and Tirzepatide
• (21:09) GLP1 non-responders
• (38:01) Sardine fasting
• (42:25) Food noise and behavioral change
• (49:35) Outro

For more information, please see the links below. Thank you for listening!

Links:

Please consider supporting us on Patreon: https://www.lowcarbmd.com/

Dr. Annette Bosworth:

• X: https://x.com/AnnetteBosworth
• Website: https://bozmd.com/
• IG: https://www.instagram.com/drboz_annettebosworthmd/

Dr. Brian Lenzkes:

• Website: https://arizonametabolichealth.com/
• Twitter: https://twitter.com/BrianLenzkes?ref_src=twsrc^google|twcamp^serp|twgr^author

Dr. Tro Kalayjian:

• Website: https://toward.health
• Twitter: https://twitter.com/DoctorTro
• IG: https://www.instagram.com/doctortro/

Toward Health App

Join a growing community of individuals who are improving their metabolic health; together.

Get started at your own pace with a self-guided curriculum developed by Dr. Tro and his care team, community chat, weekly meetings, courses, challenges, message boards and more.

Apple: https://apps.apple.com/us/app/doctor-tro/id1588693888

Google: https://play.google.com/store/apps/details?id=uk.co.disciplemedia.doctortro&hl=en_US&gl=US

Learn more: https://toward.health/community/

Brian Ruby is the founder of Medifoodz, a company focused on making therapeutic ketogenic nutrition more practical, accessible, and sustainable. Through Medifoodz's Glyvance program, Ruby is combining chef-prepared ketogenic meals with continuous glucose monitoring, digital support, and clinician oversight to help patients translate metabolic health science into everyday life. His work centers on one of the biggest challenges in nutrition-based care: not simply knowing what to eat, but making it easier to consistently eat that way.

Dr. Adrian Soto-Mota, MD, PhD, FACP is an internist, metabolic researcher, and professor whose work focuses on human metabolism, ketone biology, and evidence-based approaches to metabolic disease. He earned his PhD in Physiology and Metabolism from the University of Oxford and has conducted research on exogenous ketones, glucose metabolism, and cardiovascular health.

• Zetia Study: https://link.springer.com/article/10.1186/s12944-026-03034-w

In this episode, Dr. Brian, Dr. Tro, Dr. Adrian, and Brian Ruby talk about…

• (00:00) Intro
• (02:20) Why Brian Ruby founded Medifoodz
• (09:49) Dr. Soto Mota's recent study pitting the ADA's recommended diet and a ketogenic diet
• (22:28) The hardest barrier to entry most people struggle to overcome when starting a keto diet
• (26:15) Why CGMs are so incredibly valuable sustainability
• (32:16) Babies, dogs, and real food
• (39:24) Big Food and subsidies
• (45:58) Real food and dietary motivation
• (51:38) The AHA recommended diet diabetes reversal
• (59:15) Accepting and embracing criticism
• (01:05:51) Dr. Soto Mota's recent Zetia Study (link below)
• (01:18:24) Outro

For more information, please see the links below. Thank you for listening!

Links:

Please consider supporting us on Patreon: https://www.lowcarbmd.com/

Brian Ruby:

• Glyvance: https://medifoodz.com/
• X: https://x.com/Medifoodz

Dr. Adrian Soto Mota:

• X: https://x.com/AdrianSotoMota

Dr. Brian Lenzkes:

• Website: https://arizonametabolichealth.com/
• Twitter: https://twitter.com/BrianLenzkes?ref_src=twsrc^google|twcamp^serp|twgr^author

Dr. Tro Kalayjian:

• Website: https://toward.health
• Twitter: https://twitter.com/DoctorTro
• IG: https://www.instagram.com/doctortro/

Toward Health App

Join a growing community of individuals who are improving their metabolic health; together.

Get started at your own pace with a self-guided curriculum developed by Dr. Tro and his care team, community chat, weekly meetings, courses, challenges, message boards and more.

Apple: https://apps.apple.com/us/app/doctor-tro/id1588693888

Google: https://play.google.com/store/apps/details?id=uk.co.disciplemedia.doctortro&hl=en_US&gl=US

Learn more: https://toward.health/community/

Catherine Seo, PhD is the founder of Lipedema Simplified and director of The Lipedema Project. A psychologist, educator, and lipedema advocate, Catherine's work grew from her own experience with lipedema and lymphedema. She produced and directed the documentary The Disease They Call FAT and has dedicated her career to raising awareness, advancing research, and empowering women living with lipedema.

Siobhan Huggins is a researcher, metabolic health advocate, and Research Specialist with Lipedema Simplified and The Lipedema Project. Diagnosed with lipedema in 2021, she focuses on ketogenic nutrition, cholesterol metabolism, inflammation, and metabolic health. Siobhan is also a co-founder of Own Your Labs and an international speaker on lipedema and the potential role of low-carb nutrition in managing the condition.

In this episode, Dr. Brian, Dr. Tro, Catherine, and Siobhan talk about…

• (00:00) Intro

• (03:58) Catherine Seo's personal and professional history with lipedema

• (11:20) The gaslighting and prejudice experienced by people suffering from lipedema

• (20:31) How lipedema can impact peoples' relationships

• (28:07) How the microbiome effects everything

• (39:32) How lipedema is hormonally effected

• (53:06) How different types of fat are released

• (01:00:02) Outro

For more information, please see the links below. Thank you for listening!

Links:

Please consider supporting us on Patreon: https://www.lowcarbmd.com/

Catherine Seo, PhD:

• Lipedema Simplified: https://lipedema-simplified.org/

• X: https://x.com/catherineseo

• Lipedema: Principles and Practice of Diagnosis and Treatment: https://www.amazon.com/Lipedema-Principles-Practice-Diagnosis-Treatment/dp/1781612641

Siobhan Huggins:

• Own Your Labs: https://ownyourlabs.com/

• X: https://x.com/siobhan_huggins?lang=en

Dr. Brian Lenzkes:

• Website: https://arizonametabolichealth.com/

• Twitter: https://twitter.com/BrianLenzkes?ref_src=twsrc^google|twcamp^serp|twgr^author

Dr. Tro Kalayjian:

• Website: https://toward.health

• Twitter: https://twitter.com/DoctorTro

• IG: https://www.instagram.com/doctortro/

Toward Health App

Join a growing community of individuals who are improving their metabolic health; together.

Get started at your own pace with a self-guided curriculum developed by Dr. Tro and his care team, community chat, weekly meetings, courses, challenges, message boards and more.

Apple: https://apps.apple.com/us/app/doctor-tro/id1588693888

Google: https://play.google.com/store/apps/details?id=uk.co.disciplemedia.doctortro&hl=en_US&gl=US

Learn more: https://toward.health/community/

Sarah Aitken is a nurse practitioner, metabolic health practitioner, and the founder of Diabetes Game Changer. Her work is deeply personal: after struggling with obesity, prediabetes, and early type 2 diabetes herself, Sarah discovered the power of nutrition and lifestyle change and transformed her own health, losing nearly 100 pounds along the way. Today, she combines her clinical experience with what she learned through her own journey to help people understand insulin resistance, improve their metabolic health, and take control of type 2 diabetes through sustainable, evidence-based lifestyle changes.

In this episode, Dr. Brian, Dr. Tro and Sarah talk about…

• (00:00) Intro

• (02:49) Type 2 diabetes and body types

• (06:01) The woeful lack of education in medical schools on nutrition

• (10:32) How Sarah first educated herself on the physiology of insulin resistance and nutrition

• (20:42) The power of community and accountability

• (25:37) Providing a healthy alternative to the mega health care system that profits off of patients' illness

• (30:46) Food labels and grocery shopping

• (39:00) Fiber

• (43:43) Food, exercise, and blood sugar spikes

• (48:17) Food addiction and support

• (51:48) Outro

For more information, please see the links below. Thank you for listening!

Links:

Please consider supporting us on Patreon: https://www.lowcarbmd.com/

Sarah Aitken:

• Reversible (book): https://www.amazon.com/dp/B0GX2WJNVK

• Diabetes Game Changer: https://www.diabetesgamechanger.com/

• FB: https://www.facebook.com/diabetesgamechanger

Dr. Brian Lenzkes:

• Website: https://arizonametabolichealth.com/

• Twitter: https://twitter.com/BrianLenzkes?ref_src=twsrc^google|twcamp^serp|twgr^author

Dr. Tro Kalayjian:

• Website: https://toward.health

• Twitter: https://twitter.com/DoctorTro

• IG: https://www.instagram.com/doctortro/

Toward Health App

Join a growing community of individuals who are improving their metabolic health; together.

Get started at your own pace with a self-guided curriculum developed by Dr. Tro and his care team, community chat, weekly meetings, courses, challenges, message boards and more.

Apple: https://apps.apple.com/us/app/doctor-tro/id1588693888

Google: https://play.google.com/store/apps/details?id=uk.co.disciplemedia.doctortro&hl=en_US&gl=US

Learn more: https://toward.health/community/

Andy Schoonover is the founder and CEO of CrowdHealth, a community-powered alternative to traditional health insurance that is rethinking how Americans pay for and access healthcare. His journey began after his own family was hit with an $8,000 medical bill for his daughter's ear procedure… despite having health insurance. Frustrated by a system he believed was putting bureaucracy and financial incentives ahead of patients, Andy decided to build a better alternative. Through CrowdHealth, Andy is working to give individuals greater control over their healthcare, increase price transparency, reduce unnecessary costs, and put the patient, not the insurance company, back at the center of the system.

If you are interested in the Exit Diabetes Pilot Program, see the links below to book a screening call!

In this episode, Dr. Brian, Dr. Tro, and Andy talk about…

• (00:00) Intro

• (03:02) Issues with big health insurance companies in our post-Affordable Care Act world

• (17:00) Why the health insurance system is working against the patient

• (26:32) The slow shift away from massive healthcare companies and toward cheaper, patient-focused, sustainable options and how Crowd Health is leading the way

• (37:57) Perverse incentives and how to switch the incentive structure of the health insurance system to make patients healthy

• (42:47) Ignorance surrounding just how toxic so much of our food is

• (46:41) Crowd Health's new Exit Diabetes Pilot Program

• (01:05:05) Outro

For more information, please see the links below. Thank you for listening!

Links:

Please consider supporting us on Patreon: https://www.lowcarbmd.com/

Resources Mentioned in this Episode:

Andy Schoonover:

• CrowdHealth: https://www.joincrowdhealth.com

• Exit Diabetes Pilot Program: https://www.joincrowdhealth.com/exit-diabetes-pilot-program (Click to book a screening call!)

• X: https://x.com/andyjschoonover?lang=en

Dr. Brian Lenzkes:

• Website: https://arizonametabolichealth.com/

• Twitter: https://twitter.com/BrianLenzkes?ref_src=twsrc^google|twcamp^serp|twgr^author

Dr. Tro Kalayjian:

• Website: https://toward.health

• Twitter: https://twitter.com/DoctorTro

• IG: https://www.instagram.com/doctortro/

Toward Health App

Join a growing community of individuals who are improving their metabolic health; together.

Get started at your own pace with a self-guided curriculum developed by Dr. Tro and his care team, community chat, weekly meetings, courses, challenges, message boards and more.

Apple: https://apps.apple.com/us/app/doctor-tro/id1588693888

Google: https://play.google.com/store/apps/details?id=uk.co.disciplemedia.doctortro&hl=en_US&gl=US

Learn more: https://toward.health/community/

Dr. Philip Ovadia is a board-certified heart surgeon on a mission to help people stay off his operating table. After overcoming his own struggles with obesity and poor metabolic health, he shifted his focus from treating advanced heart disease to preventing it by addressing its root causes. As the bestselling author of Stay Off My Operating Table, Dr. Ovadia challenges conventional thinking about heart health and advocates for nutrition, metabolic health, and lifestyle as the foundation for preventing cardiovascular disease. Through his clinical work, writing, and education, he empowers people to take control of their health long before surgery becomes necessary.

In this episode, Drs. Brian and Philip talk about…

• (00:00) Intro

• (01:21) Dr. Ovadia's personal health journey

• (05:09) Insulin resistance and heart disease

• (09:29) Insulin resistance, inflammation, and imaging

• (25:44) GLP medications and heart disease risk

• (28:47) Why meat is essential for human health

• (33:17) How Dr. Ovadia's colleagues have reacted to his unconventional dietary views and how the medical field is reacting to the keto/low carb revolution

• (39:25) Various lab tests and plaque progression

• (41:19) Gut health and the carnivore diet

• (42:54) Fermentation and detoxifying foods

• (46:29) Outro

For more information, please see the links below. Thank you for listening!

Links:

Please consider supporting us on Patreon: https://www.lowcarbmd.com/

Dr. Philip Ovadia:

• Books: https://ovadiahearthealth.com/books/

• Website: https://ovadiahearthealth.com/

• X: https://x.com/ifixhearts

Dr. Brian Lenzkes:

• Website: https://arizonametabolichealth.com/

• Twitter: https://twitter.com/BrianLenzkes?ref_src=twsrc^google|twcamp^serp|twgr^author

Dr. Tro Kalayjian:

• Website: https://toward.health

• Twitter: https://twitter.com/DoctorTro

• IG: https://www.instagram.com/doctortro/

Toward Health App

Join a growing community of individuals who are improving their metabolic health; together.

Get started at your own pace with a self-guided curriculum developed by Dr. Tro and his care team, community chat, weekly meetings, courses, challenges, message boards and more.

Apple: https://apps.apple.com/us/app/doctor-tro/id1588693888

Google: https://play.google.com/store/apps/details?id=uk.co.disciplemedia.doctortro&hl=en_US&gl=US

Learn more: https://toward.health/community/

Thomas Mullooly is a Certified Financial Planner, Investment Adviser Representative, and President of Mullooly Asset Management, Inc. After receiving a big surprise in the form of a Type 2 Diabetes diagnosis, Thomas was determined to find a long term solution rather than accept his doctor's proclamation that he would have to take Metformin for the rest of his life. Now, 100 lbs. lighter and in the best metabolic/physical shape of his life, he's convinced he has found the solution for him.

In this episode, Dr. Brian, Dr. Tro, and Thomas talk about…

• (00:00) Intro
• (02:27) How Thomas found out he had Type 2 Diabetes and how he discovered the key to reversing it
• (10:46) Intermittent fasting and the keto diet
• (11:46) How Thomas slowly gained weight and inched closer and closer to metabolic disease
• (19:02) Perseverance and success
• (26:37) Cold plunge and cold exposure
• (31:22) Breaking through weight-loss stalls
• (35:26) Motivation for sticking with the lifestyle changes you've committed to
• (43:51) Outro

For more information, please see the links below. Thank you for listening!

Links:

Please consider supporting us on Patreon: https://www.lowcarbmd.com/

Resources Mentioned in this Episode:

Thomas Mullooly:

• Mullooly Asset Management: https://mullooly.net/
• X: https://x.com/tommullooly
• Linkedin: https://www.linkedin.com/in/njfinancialplanner/

Dr. Brian Lenzkes:

• Website: https://arizonametabolichealth.com/
• Twitter: https://twitter.com/BrianLenzkes?ref_src=twsrc^google|twcamp^serp|twgr^author

Dr. Tro Kalayjian:

• Website: https://toward.health
• Twitter: https://twitter.com/DoctorTro
• IG: https://www.instagram.com/doctortro/

Toward Health App

Join a growing community of individuals who are improving their metabolic health; together.

Get started at your own pace with a self-guided curriculum developed by Dr. Tro and his care team, community chat, weekly meetings, courses, challenges, message boards and more.

Apple: https://apps.apple.com/us/app/doctor-tro/id1588693888

Google: https://play.google.com/store/apps/details?id=uk.co.disciplemedia.doctortro&hl=en_US&gl=US

Learn more: https://toward.health/community/

After coming face to face with the reality of her family's poor health, Sara decided it was time to break the cycle of obesity and disease that was plaguing them. She spearheaded the movement and rallied her children and husband to join her and now, five years later, they have collectively lost 335 pounds! Not only that, but they are feeling physically and emotionally better than ever.

In this episode, Dr. Brian, Dr. Tro, and Sara talk about…

• (00:00) Intro
• (02:59) How Sara broke the cycle of poor health for herself and her family
• (13:28) Sara's diet history
• (16:33) Depression, stress eating, and mindset
• (32:10) Exercise and metabolic health
• (36:32) How Sara was able to rally her whole family to join her on a health journey
• (45:01) Advice for those struggling with depression and obesity
• (50:19) Habitual eating and fasting
• (52:55) Outro

For more information, please see the links below. Thank you for listening!

Links:

Please consider supporting us on Patreon: https://www.lowcarbmd.com/

Dr. Brian Lenzkes:

• Website: https://arizonametabolichealth.com/
• Twitter: https://twitter.com/BrianLenzkes?ref_src=twsrc^google|twcamp^serp|twgr^author

Dr. Tro Kalayjian:

• Website: https://toward.health
• Twitter: https://twitter.com/DoctorTro
• IG: https://www.instagram.com/doctortro/

Toward Health App

Join a growing community of individuals who are improving their metabolic health; together.

Get started at your own pace with a self-guided curriculum developed by Dr. Tro and his care team, community chat, weekly meetings, courses, challenges, message boards and more.

Apple: https://apps.apple.com/us/app/doctor-tro/id1588693888

Google: https://play.google.com/store/apps/details?id=uk.co.disciplemedia.doctortro&hl=en_US&gl=US

Learn more: https://toward.health/community/

Melania Behrens is a registered dietitian passionate about helping people improve their metabolic health through evidence-based nutrition and sustainable lifestyle change. She specializes in low-carbohydrate nutrition and works with individuals to address the root causes of chronic disease, optimize metabolic function, and build healthier relationships with food. Melania is dedicated to translating the latest nutrition science into practical strategies that empower people to achieve lasting health and well-being.

In this episode, Dr. Brian, Dr. Tro, and Melania talk about…

• (00:00) Intro

• (02:33) How Melania got started in dietetics and a little bit about her incredibly comprehensive professional background in the metabolic health space

• (07:14) How the dietetics field has changed since Melania first entered it

• (10:32) Sarah Hallberg's incredible Ted Talk on Type 2 Diabetes and how it impacted Melania

• (14:12) Hospital food service and the keto diet revolution that has been sweeping the nation

• (15:23) Beurocratic issues facing the success of the dietetics field going forward

• (22:14) Melania's ideal patient

• (26:56) How Melania approaches a new patient who wants to lose weight

• (30:00) How Melania motivates and empowers people to succeed in achieving their health goals

• (32:49) Diet and exercise

• (37:29) Outro/plugs

For more information, please see the links below. Thank you for listening!

Links:

Please consider supporting us on Patreon: https://www.lowcarbmd.com/

Resources Mentioned in this Episode:

• Sarah Hallberg's Ted Talk: https://www.youtube.com/watch?v=da1vvigy5tQ

Melania Behrens:

• Keto RD: https://www.ketord.com/

• X: https://x.com/MelaniaRDLD

Dr. Brian Lenzkes:

• Website: https://arizonametabolichealth.com/

• Twitter: https://twitter.com/BrianLenzkes?ref_src=twsrc^google|twcamp^serp|twgr^author

Dr. Tro Kalayjian:

• Website: https://toward.health

• Twitter: https://twitter.com/DoctorTro

• IG: https://www.instagram.com/doctortro/

Toward Health App

Join a growing community of individuals who are improving their metabolic health; together.

Get started at your own pace with a self-guided curriculum developed by Dr. Tro and his care team, community chat, weekly meetings, courses, challenges, message boards and more.

Apple: https://apps.apple.com/us/app/doctor-tro/id1588693888

Google: https://play.google.com/store/apps/details?id=uk.co.disciplemedia.doctortro&hl=en_US&gl=US

Learn more: https://toward.health/community/