In today's episode, Dr. Scott Watier and Tommy Welling break down a groundbreaking 2025 systematic review examining intermittent fasting's impact on cardiovascular disease prevention, revealing how modified alternate day fasting and time-restricted eating outperform traditional calorie restriction for reducing blood pressure, blood sugar, and waist circumference. They explore the practical application of "fast cycling"—strategically combining daily 16-18 hour fasts with weekly 24-48 hour extended fasts—to maximize both adherence and metabolic benefits without feeling deprived. The hosts emphasize that these research findings reflect the power of fasting timing itself, independent of strict dietary rules, making this approach more sustainable than traditional dieting. They provide actionable guidance on establishing a consistent fasting baseline while incorporating periodic extended fasts to leverage the cardiometabolic advantages seen in the research. Whether you're looking to prevent cardiovascular disease, break through a weight loss plateau, or simply establish a maintainable fasting lifestyle, this episode delivers the evidence-based framework and practical strategies to make fasting work for your long-term health goals.

⁠⁠⁠⁠⁠⁠Take the NEW FASTING PERSONA QUIZ! - The Key to Unlocking Sustainable Weight Loss With Fasting!⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

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Let’s continue the conversation. Click the link below to JOIN the ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Fasting For Life Community⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠, a group of like-minded, new, and experienced fasters! The first two rules of fasting need not apply!

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https://pmc.ncbi.nlm.nih.gov/articles/PMC12289860/pdf/13668_2025_Article_684.pdf

This groundbreaking episode unveils Stanford Professor Michael Snyder's revolutionary research published in Nature Biomedical Engineering revealing that type 2 diabetes and insulin resistance aren't single diseases but four distinct metabolic subtypes requiring personalized fasting and nutrition strategies. The hosts decode how muscle insulin resistance demands early time-restricted eating with 18:6 or OMAD plus resistance training, beta cell dysfunction requires gentle 16:8 fasting while avoiding extended fasts to prevent pancreatic burnout, impaired incretin effect needs pre-meal walking with fermented foods to enhance gut hormone signaling, and liver glucose dysregulation necessitates 30-36 hour fasts weekly to reset hepatic insulin resistance and stop the liver's continuous glucose output. Dr. Scott and Tommy explain why A1C measurements provide almost no insight into underlying mechanisms, with individuals showing normal A1C yet severe insulin resistance while others display pre-diabetic A1C with preserved insulin sensitivity, making traditional one-size-fits-all weight loss recommendations fundamentally flawed. The episode introduces at-home oral glucose tolerance testing to decode personal glucose curves and identify specific pathology, while emphasizing foundational recommendations—early meals, resistance training, post-meal walks, protein prioritization, sleep protection, and stress management—move the needle for most people regardless of subtype, with personalized optimization becoming critical for those stuck despite consistent effort.

⁠⁠⁠⁠⁠Take the NEW FASTING PERSONA QUIZ! - The Key to Unlocking Sustainable Weight Loss With Fasting!⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

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Get your⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ FREE BOX OF LMNT⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ hydration support for the perfect electrolyte balance for your fasting lifestyle with your first purchase⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ here!⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

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Let’s continue the conversation. Click the link below to JOIN the ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Fasting For Life Community⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠, a group of like-minded, new, and experienced fasters! The first two rules of fasting need not apply!

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This listener Q&A episode tackles the most common fasting challenges with evidence-based solutions, addressing Monica's self-sabotage pattern after reaching new low weights by explaining the body's three-pronged defense system (defend phase preventing further loss, restore phase increasing regain rate, and prevent phase reducing future weight loss probability) that creates powerful physiological resistance requiring equally comprehensive counter-strategies. The hosts reveal how metabolic adaptation activates during weight loss like a toddler throwing a tantrum, making the body fight harder at new weight thresholds, while providing practical "when-then planning" to manage the slippery slope of increased hunger and reduced willpower that emerges from dopamine deficits caused by sleep disruption and stress. They address Emily's two-week plateau after losing seven pounds initially with 20:4 fasting, explaining the critical distinction between water weight loss from glycogen depletion versus true fat loss, recommending the Blueprint to Fasting for Fat Loss resource and strategic window timing adjustments to restart momentum. Patty's wine consumption question during OMAD receives honest analysis of alcohol's metabolic priority over fat burning, sleep disruption effects reducing next-day metabolic efficiency, and dose-dependent impact on hormones especially for postmenopausal women, with recommendations to shift from daily to occasional consumption strategically timed for better recovery. The episode covers supplement timing during fasting windows (berberine, creatine recommended daily for consistency despite potential stomach sensitivity), addresses sleep disturbances from excessive 48-hour fasting during maintenance (recommending 24-36 hour alternatives to protect sleep quality over marginal metabolic gains), and explains post-meal walking benefits for glucose management through skeletal muscle uptake and improved insulin sensitivity, even when continuous glucose monitors show delayed rather than reduced spikes. Throughout, Scott and Tommy emphasize viewing fat loss and maintenance as a continuum rather than separate phases, building sustainable habits during weight loss that seamlessly transition to lifelong maintenance, positioning their upcoming pre-Thanksgiving seven-day challenge as strategically timed to establish momentum before the holiday season while reinforcing that successful fasting integration requires addressing foundational lifestyle factors of stress, sleep, food relationships, and mindset alongside fasting schedules.

⁠⁠⁠⁠Take the NEW FASTING PERSONA QUIZ! - The Key to Unlocking Sustainable Weight Loss With Fasting!⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

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Get your⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ FREE BOX OF LMNT⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ hydration support for the perfect electrolyte balance for your fasting lifestyle with your first purchase⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ here!⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

Get ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠25% off a Keto-Mojo⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ blood glucose and ketone monitor (discount shown at checkout)! ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Click here!⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

Our Community:

Let’s continue the conversation. Click the link below to JOIN the ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Fasting For Life Community⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠, a group of like-minded, new, and experienced fasters! The first two rules of fasting need not apply!

If you enjoy the podcast, please tap the stars below and consider leaving a short review on Apple Podcasts/iTunes. It takes less than 60 seconds, and it helps bring you the best original content each week. We also enjoy reading them!

***JOIN THE NEXT MASTER YOUR FASTING CHALLENGE THAT STARTS October 1st, 2025!***

We’ll GUIDE you on how to FAST to LOSE FAT for good, and use ‘fast cycling’ to achieve uncommon results!

⁠⁠REGISTER HERE!⁠⁠ Click the link for DATES, DETAILS, and FAQs!

⁠⁠⁠Take the NEW FASTING PERSONA QUIZ! - The Key to Unlocking Sustainable Weight Loss With Fasting!⁠⁠⁠⁠⁠⁠⁠⁠⁠

Resources and Downloads:

Partner Links:

Get your⁠⁠⁠⁠⁠⁠⁠⁠⁠ FREE BOX OF LMNT⁠⁠⁠⁠⁠⁠⁠⁠⁠ hydration support for the perfect electrolyte balance for your fasting lifestyle with your first purchase⁠⁠⁠⁠⁠⁠⁠⁠⁠ here!⁠⁠⁠⁠⁠⁠⁠⁠⁠

Get ⁠⁠⁠⁠⁠⁠⁠⁠⁠25% off a Keto-Mojo⁠⁠⁠⁠⁠⁠⁠⁠⁠ blood glucose and ketone monitor (discount shown at checkout)! ⁠⁠⁠⁠⁠⁠⁠⁠⁠Click here!⁠⁠⁠⁠⁠⁠⁠⁠⁠

Our Community:

Let’s continue the conversation. Click the link below to JOIN the ⁠⁠⁠⁠⁠⁠⁠⁠⁠Fasting For Life Community⁠⁠⁠⁠⁠⁠⁠⁠⁠, a group of like-minded, new, and experienced fasters! The first two rules of fasting need not apply!

If you enjoy the podcast, please tap the stars below and consider leaving a short review on Apple Podcasts/iTunes. It takes less than 60 seconds, and it helps bring you the best original content each week. We also enjoy reading them!

***JOIN THE NEXT MASTER YOUR FASTING CHALLENGE THAT STARTS October 1st, 2025!***

We’ll GUIDE you on how to FAST to LOSE FAT for good, and use ‘fast cycling’ to achieve uncommon results!

⁠⁠REGISTER HERE!⁠⁠ Click the link for DATES, DETAILS, and FAQs!

⁠⁠⁠⁠Take the NEW FASTING PERSONA QUIZ! - The Key to Unlocking Sustainable Weight Loss With Fasting!⁠⁠⁠⁠⁠⁠⁠⁠⁠

Resources and Downloads:

Partner Links:

Get your⁠⁠⁠⁠⁠⁠⁠⁠⁠ FREE BOX OF LMNT⁠⁠⁠⁠⁠⁠⁠⁠⁠ hydration support for the perfect electrolyte balance for your fasting lifestyle with your first purchase⁠⁠⁠⁠⁠⁠⁠⁠⁠ here!⁠⁠⁠⁠⁠⁠⁠⁠⁠

Get ⁠⁠⁠⁠⁠⁠⁠⁠⁠25% off a Keto-Mojo⁠⁠⁠⁠⁠⁠⁠⁠⁠ blood glucose and ketone monitor (discount shown at checkout)! ⁠⁠⁠⁠⁠⁠⁠⁠⁠Click here!⁠⁠⁠⁠⁠⁠⁠⁠⁠

Our Community:

Let’s continue the conversation. Click the link below to JOIN the ⁠⁠⁠⁠⁠⁠⁠⁠⁠Fasting For Life Community⁠⁠⁠⁠⁠⁠⁠⁠⁠, a group of like-minded, new, and experienced fasters! The first two rules of fasting need not apply!

If you enjoy the podcast, please tap the stars below and consider leaving a short review on Apple Podcasts/iTunes. It takes less than 60 seconds, and it helps bring you the best original content each week. We also enjoy reading them!

***JOIN THE NEXT MASTER YOUR FASTING CHALLENGE THAT STARTS October 1st, 2025!***

We’ll GUIDE you on how to FAST to LOSE FAT for good, and use ‘fast cycling’ to achieve uncommon results!

⁠REGISTER HERE!⁠ Click the link for DATES, DETAILS, and FAQs!

⁠⁠⁠Take the NEW FASTING PERSONA QUIZ! - The Key to Unlocking Sustainable Weight Loss With Fasting!⁠⁠⁠⁠⁠⁠⁠⁠

Resources and Downloads:

Partner Links:

Get your⁠⁠⁠⁠⁠⁠⁠⁠ FREE BOX OF LMNT⁠⁠⁠⁠⁠⁠⁠⁠ hydration support for the perfect electrolyte balance for your fasting lifestyle with your first purchase⁠⁠⁠⁠⁠⁠⁠⁠ here!⁠⁠⁠⁠⁠⁠⁠⁠

Get ⁠⁠⁠⁠⁠⁠⁠⁠25% off a Keto-Mojo⁠⁠⁠⁠⁠⁠⁠⁠ blood glucose and ketone monitor (discount shown at checkout)! ⁠⁠⁠⁠⁠⁠⁠⁠Click here!⁠⁠⁠⁠⁠⁠⁠⁠

Our Community:

Let’s continue the conversation. Click the link below to JOIN the ⁠⁠⁠⁠⁠⁠⁠⁠Fasting For Life Community⁠⁠⁠⁠⁠⁠⁠⁠, a group of like-minded, new, and experienced fasters! The first two rules of fasting need not apply!

If you enjoy the podcast, please tap the stars below and consider leaving a short review on Apple Podcasts/iTunes. It takes less than 60 seconds, and it helps bring you the best original content each week. We also enjoy reading them!

Article Links:⁠

***JOIN THE NEXT MASTER YOUR FASTING CHALLENGE THAT STARTS October 1st, 2025!***

We’ll GUIDE you on how to FAST to LOSE FAT for good, and use ‘fast cycling’ to achieve uncommon results!

REGISTER HERE! Click the link for DATES, DETAILS, and FAQs!

This episode examines a comprehensive narrative review analyzing fasting's profound effects on metabolic hormones and functions across 13 different studies and fasting protocols. Dr. Scott and Tommy reveal a game-changing mental approach: shift from counting down your fasting timer to counting up the powerful benefits accumulating in your body during each fast. The research demonstrates remarkable results from consistent intermittent fasting practices - 24-hour fasts performed three times weekly in women produced increased antioxidant activity, weight reduction, improved morning glucose levels, better A1C readings, and significant improvements in blood pressure, cholesterol, and triglycerides. Learn how 16:8 time-restricted eating for 12 weeks dramatically enhanced multiple metabolic markers in patients with metabolic syndrome, while understanding the crucial differences between fasting effects in lean individuals versus those with excess weight. The hosts clarify testosterone concerns, explaining why lean men may see temporary decreases with extended fasting protocols (typically due to inadvertent under-eating) while overweight men experience increases through improved testicular function and reduced estrogen conversion. Discover practical strategies for building sustainable fasting habits through progressive skill development rather than perfectionist approaches, including proper electrolyte management, leveraging gut microbiome improvements, and strategic meal planning for optimal fast-breaking. This episode reframes fasting as a learnable skill requiring practice and adaptation, providing specific guidance for developing your personal fasting toolkit based on your health status, body composition, and long-term metabolic optimization goals.

⁠⁠Take the NEW FASTING PERSONA QUIZ! - The Key to Unlocking Sustainable Weight Loss With Fasting!⁠⁠⁠⁠⁠⁠⁠

Resources and Downloads:

Partner Links:

Get your⁠⁠⁠⁠⁠⁠⁠ FREE BOX OF LMNT⁠⁠⁠⁠⁠⁠⁠ hydration support for the perfect electrolyte balance for your fasting lifestyle with your first purchase⁠⁠⁠⁠⁠⁠⁠ here!⁠⁠⁠⁠⁠⁠⁠

Get ⁠⁠⁠⁠⁠⁠⁠25% off a Keto-Mojo⁠⁠⁠⁠⁠⁠⁠ blood glucose and ketone monitor (discount shown at checkout)! ⁠⁠⁠⁠⁠⁠⁠Click here!⁠⁠⁠⁠⁠⁠⁠

Our Community:

Let’s continue the conversation. Click the link below to JOIN the ⁠⁠⁠⁠⁠⁠⁠Fasting For Life Community⁠⁠⁠⁠⁠⁠⁠, a group of like-minded, new, and experienced fasters! The first two rules of fasting need not apply!

If you enjoy the podcast, please tap the stars below and consider leaving a short review on Apple Podcasts/iTunes. It takes less than 60 seconds, and it helps bring you the best original content each week. We also enjoy reading them!

Article Links: https://pmc.ncbi.nlm.nih.gov/articles/PMC11560338/pdf/2188-2126-70-5-0348.pdf

This episode analyzes a groundbreaking 12-week study comparing volumetric diet approaches with 16:8 time-restricted eating, revealing why intermittent fasting leads to better long-term adherence and sustainability. Dr. Scott and Tommy break down research showing that while both groups achieved similar weight loss and body composition improvements, the fasting group maintained 83% adherence (5.8 days per week) compared to 76% for the volumetric diet group - a crucial 7% difference that compounds significantly over time. Learn about the hedonic food scale and how high-hedonic foods (chocolate, chips, nut butters) versus low-hedonic foods (vegetables, soups, melons) impact your fasting success and food choices. Discover how to combine the best of both approaches by using volumetric eating principles as fast-breakers - incorporating water-based soups, raw vegetables with salsa, and high-water fruits to naturally reduce caloric density while maintaining satisfaction. The hosts explain why fasting simplifies decision-making, reduces food noise, and eliminates decision fatigue compared to calorie counting and macro tracking. Get practical strategies for closing eating windows successfully, preventing late-night pantry raids, and using volumetric foods as stepping stones toward cleaner fasting habits. This episode provides evidence that fasting's simplicity leads to better long-term results, while offering tactical ways to leverage volume eating during nutrition windows for enhanced satiety and easier window closure, ultimately supporting sustainable weight loss without the complexity of traditional diet approaches.

⁠Take the NEW FASTING PERSONA QUIZ! - The Key to Unlocking Sustainable Weight Loss With Fasting!⁠⁠⁠⁠⁠⁠

Resources and Downloads:

Partner Links:

Get your⁠⁠⁠⁠⁠⁠ FREE BOX OF LMNT⁠⁠⁠⁠⁠⁠ hydration support for the perfect electrolyte balance for your fasting lifestyle with your first purchase⁠⁠⁠⁠⁠⁠ here!⁠⁠⁠⁠⁠⁠

Get ⁠⁠⁠⁠⁠⁠25% off a Keto-Mojo⁠⁠⁠⁠⁠⁠ blood glucose and ketone monitor (discount shown at checkout)! ⁠⁠⁠⁠⁠⁠Click here!⁠⁠⁠⁠⁠⁠

Our Community:

Let’s continue the conversation. Click the link below to JOIN the ⁠⁠⁠⁠⁠⁠Fasting For Life Community⁠⁠⁠⁠⁠⁠, a group of like-minded, new, and experienced fasters! The first two rules of fasting need not apply!

If you enjoy the podcast, please tap the stars below and consider leaving a short review on Apple Podcasts/iTunes. It takes less than 60 seconds, and it helps bring you the best original content each week. We also enjoy reading them!

Article Links:

https://pmc.ncbi.nlm.nih.gov/articles/PMC12175453/pdf/12937_2025_Article_1167.pdf

This episode breaks down groundbreaking research on hyper-caloric 16:8 time-restricted eating during 8 weeks of resistance training, proving you can build muscle and get stronger while maintaining an intermittent fasting lifestyle. Dr. Scott and Tommy analyze a study comparing fasted vs fed workout groups, revealing that the time-restricted eating group gained 50% more muscle mass (2.67kg vs 1.82kg) while gaining significantly less fat (0.26kg vs 1.67kg) even in a caloric surplus. Discover why fasted training leads to superior body composition changes - more muscle growth with minimal fat gain - making it ideal for physique-focused goals and maintenance phases. Learn the trade-offs: while the fed group showed slightly better strength gains (particularly in squat performance), the fasted group achieved the same total weight lifted with fewer reps, suggesting greater training efficiency. The hosts explain why this matters for long-term fasting lifestyle success, especially for those reaching maintenance goals who want to continue improving body composition without regaining weight. Get practical strategies for timing workouts with eating windows, understanding the adaptation period for fasted training, and choosing between performance-focused vs body composition-focused approaches. This episode provides evidence-based guidance for combining resistance training with intermittent fasting, showing that you don't have to sacrifice muscle building for fat loss - you can optimize both simultaneously with proper timing and nutrition strategies.

⁠Take the NEW FASTING PERSONA QUIZ! - The Key to Unlocking Sustainable Weight Loss With Fasting!⁠⁠⁠⁠⁠⁠

Resources and Downloads:

Partner Links:

Get your⁠⁠⁠⁠⁠⁠ FREE BOX OF LMNT⁠⁠⁠⁠⁠⁠ hydration support for the perfect electrolyte balance for your fasting lifestyle with your first purchase⁠⁠⁠⁠⁠⁠ here!⁠⁠⁠⁠⁠⁠

Get ⁠⁠⁠⁠⁠⁠25% off a Keto-Mojo⁠⁠⁠⁠⁠⁠ blood glucose and ketone monitor (discount shown at checkout)! ⁠⁠⁠⁠⁠⁠Click here!⁠⁠⁠⁠⁠⁠

Our Community:

Let’s continue the conversation. Click the link below to JOIN the ⁠⁠⁠⁠⁠⁠Fasting For Life Community⁠⁠⁠⁠⁠⁠, a group of like-minded, new, and experienced fasters! The first two rules of fasting need not apply!

If you enjoy the podcast, please tap the stars below and consider leaving a short review on Apple Podcasts/iTunes. It takes less than 60 seconds, and it helps bring you the best original content each week. We also enjoy reading them!

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This listener Q&A episode tackles the most common intermittent fasting challenges with practical, science-backed solutions. Dr. Scott and Tommy address Nick's testosterone concerns on low-carb diets, explaining how early-day carb timing with circadian rhythm optimization can maintain hormone levels while supporting fasting goals. Learn why combining morning carbohydrates with evening protein creates the ideal metabolic environment for both performance and fat burning. Discover solutions for Carrie's post-workout hunger struggles, including why strength training increases ghrelin and depletes glycogen stores, making fasted training more challenging but ultimately more effective with proper timing and hydration strategies. The hosts dive deep into plateau-busting tactics for OMAD practitioners, explaining why Jean Marie's 3-pound fluctuations are normal and how to break through stalls by varying meal timing, prioritizing non-scale victories, and understanding that metabolic changes occur beneath the surface even when the scale doesn't move. Address common snacking temptations during extended fasts, with Gary's nut-snacking dilemma at the 24-hour mark - learn why this happens during the glycogen-to-ketosis transition and practical replacement strategies. Get insights on keeping "trigger foods" out of the house, using the "who are these for?" technique, and creating habit replacements instead of habit voids. This episode provides real-world solutions for the most frustrating aspects of intermittent fasting, helping you troubleshoot common obstacles while maintaining long-term success with your fasting lifestyle.

⁠Take the NEW FASTING PERSONA QUIZ! - The Key to Unlocking Sustainable Weight Loss With Fasting!⁠⁠⁠⁠⁠

Resources and Downloads:

Partner Links:

Get your⁠⁠⁠⁠⁠ FREE BOX OF LMNT⁠⁠⁠⁠⁠ hydration support for the perfect electrolyte balance for your fasting lifestyle with your first purchase⁠⁠⁠⁠⁠ here!⁠⁠⁠⁠⁠

Get ⁠⁠⁠⁠⁠25% off a Keto-Mojo⁠⁠⁠⁠⁠ blood glucose and ketone monitor (discount shown at checkout)! ⁠⁠⁠⁠⁠Click here!⁠⁠⁠⁠⁠

Our Community:

Let’s continue the conversation. Click the link below to JOIN the ⁠⁠⁠⁠⁠Fasting For Life Community⁠⁠⁠⁠⁠, a group of like-minded, new, and experienced fasters! The first two rules of fasting need not apply!

If you enjoy the podcast, please tap the stars below and consider leaving a short review on Apple Podcasts/iTunes. It takes less than 60 seconds, and it helps bring you the best original content each week. We also enjoy reading them!