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In today's episode, Dr. Scott Watier and Tommy Welling dissect a groundbreaking 2025 study revealing how the macronutrient composition of your last meal before fasting dramatically affects your ability to enter ketosis and burn fat during a 24-hour fast. They unpack shocking findings showing that participants who consumed a low-carb, high-fat meal reached nutritional ketosis within 12 hours, while those who ate a high-carb, low-fat meal never achieved ketosis during the entire 24-hour period, despite consuming the same number of calories and protein. The hosts explain how this simple meal composition shift increased fat-burning hormones like glucagon by 24% and naturally boosted GLP-1 and GIP levels by over 30%, providing the same appetite-suppressing benefits people seek from medications without pharmaceutical intervention. They address the common plateau problem many fasters experience when doing consistent OMAD, revealing that unintentional macronutrient shifts toward higher carbs can completely block fat burning even while maintaining strict fasting windows. This episode delivers an immediately actionable strategy to optimize your pre-fast meal composition and meal timing, particularly highlighting why dinner OMAD requires even more careful food choices than breakfast OMAD due to circadian biology and insulin sensitivity differences throughout the day.
Take the NEW FASTING PERSONA QUIZ! - The Key to Unlocking Sustainable Weight Loss With Fasting!
Resources and Downloads:
Partner Links:
Get your FREE BOX OF LMNT hydration support for the perfect electrolyte balance for your fasting lifestyle with your first purchase here!
Get 30% off a Keto-Mojo blood glucose and ketone monitor (discount shown at checkout)! Click here!
Our Community:
Let’s continue the conversation. Click the link below to JOIN the Fasting For Life Community, a group of like-minded, new, and experienced fasters! The first two rules of fasting need not apply!
If you enjoy the podcast, please tap the stars below and consider leaving a short review on Apple Podcasts/iTunes. It takes less than 60 seconds, and it helps bring you the best original content each week. We also enjoy reading them!
Article Links:
https://pmc.ncbi.nlm.nih.gov/articles/PMC11998415/pdf/12986_2025_Article_920.pdf
By Dr. Scott Watier & Tommy Welling4.7
11141,114 ratings
In today's episode, Dr. Scott Watier and Tommy Welling dissect a groundbreaking 2025 study revealing how the macronutrient composition of your last meal before fasting dramatically affects your ability to enter ketosis and burn fat during a 24-hour fast. They unpack shocking findings showing that participants who consumed a low-carb, high-fat meal reached nutritional ketosis within 12 hours, while those who ate a high-carb, low-fat meal never achieved ketosis during the entire 24-hour period, despite consuming the same number of calories and protein. The hosts explain how this simple meal composition shift increased fat-burning hormones like glucagon by 24% and naturally boosted GLP-1 and GIP levels by over 30%, providing the same appetite-suppressing benefits people seek from medications without pharmaceutical intervention. They address the common plateau problem many fasters experience when doing consistent OMAD, revealing that unintentional macronutrient shifts toward higher carbs can completely block fat burning even while maintaining strict fasting windows. This episode delivers an immediately actionable strategy to optimize your pre-fast meal composition and meal timing, particularly highlighting why dinner OMAD requires even more careful food choices than breakfast OMAD due to circadian biology and insulin sensitivity differences throughout the day.
Take the NEW FASTING PERSONA QUIZ! - The Key to Unlocking Sustainable Weight Loss With Fasting!
Resources and Downloads:
Partner Links:
Get your FREE BOX OF LMNT hydration support for the perfect electrolyte balance for your fasting lifestyle with your first purchase here!
Get 30% off a Keto-Mojo blood glucose and ketone monitor (discount shown at checkout)! Click here!
Our Community:
Let’s continue the conversation. Click the link below to JOIN the Fasting For Life Community, a group of like-minded, new, and experienced fasters! The first two rules of fasting need not apply!
If you enjoy the podcast, please tap the stars below and consider leaving a short review on Apple Podcasts/iTunes. It takes less than 60 seconds, and it helps bring you the best original content each week. We also enjoy reading them!
Article Links:
https://pmc.ncbi.nlm.nih.gov/articles/PMC11998415/pdf/12986_2025_Article_920.pdf

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