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In this timely episode of No Way Out, neuroscientist and systems thinker Sean Manion joins Ponch and Mark to explore the untapped potential of the OODA Loop beyond its military origins. Sean brings over 25 years of experience in neuroscience, clinical research, and health technology to an expansive discussion that redefines the OODA Loop through the lens of natural sciences, cybernetics, complexity theory, and neuroscience.

The conversation dives into how the OODA Loop’s foundation in feedback systems aligns with modern advances in AI, particularly reinforcement learning and active inference models. Sean explains how concepts from cybernetics and information theory can help build more adaptive, energy-efficient AI systems that reflect the dynamics of living systems rather than rigid, linear processing.

Listeners will discover:

• How cybernetics, the science of communication and control in living and machine systems, influenced both John Boyd’s thinking and the evolution of AI.
• The critical role of neuroscience in developing more explainable and trustworthy AI, moving beyond today’s opaque, energy-intensive models.
• How feedback loops, adaptive systems, and even epigenetics play into decision-making processes in humans decision making. 
• The intersection of the OODA Loop with symbolic AI, neuromorphic computing, and complex adaptive systems, showing pathways to a more holistic, biologically inspired AI.

Sean challenges listeners to rethink intelligence itself, arguing that modern AI tools like large language models are not true intelligence but instead tools that mimic limited aspects of human cognition. Drawing on Boyd’s interdisciplinary approach, Sean makes the

John R. Boyd's Conceptual Spiral was originally titled No Way Out. In his own words: 

“There is no way out unless we can eliminate the features just cited. Since we don’t know how to do this, we must continue the whirl of reorientation…”

March 25, 2025

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