The Audio PANCE and PANRE Physician Assistant Board Review Podcast

The Audio PANCE and PANRE Physician Assistant Board Review Podcast

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The Audio PANCE and PANRE Physician Assistant Board Review Podcast episodes

  • Podcast Episode 77: The Audio PANCE and PANRE Board Review Podcast

    Welcome to episode 77 of the Audio PANCE and PANRE PA Board Review Podcast.

    Join me as I cover ten PANCE and PANRE Board review questions from the Smarty PANCE course content following the NCCPA™ content blueprint (download the FREE cheat sheet).

    Special from today’s episode:

    • Download your copy of the Free Trello Smarty PANCE NCCPA™ Blueprint Study Plan
    • Follow The Daily PANCE Blueprint on Instagram
    • Follow The Daily PANCE Blueprint on Facebook
    • This week we will be covering ten general board review questions based on the NCCPA PANCE and PANRE Content Blueprints. 

      Below you will find an interactive exam to complement the podcast.

      The Audio PANCE and PANRE Physician Assistant Board Review Podcast

      I hope you enjoy this free audio component to the examination portion of this site. The full board review includes over 2,000 interactive board review questions and is available to all members of the PANCE and PANRE Academy and Smarty PANCE.

      • You can download and listen to past FREE episodes here, on iTunes, on Google Play Music or Stitcher Radio.
      • You can listen to the latest episode, take an interactive quiz and download your results below.
      • Listen Carefully Then Take The Practice Exam

        If you can’t see the audio player click here to listen to the full episode.

        Podcast Episode 77: Ten Question PANCE and PANRE Podcast Quiz

        The following questions are linked to NCCPA Content Blueprint lessons from the Smarty PANCE and PANRE Board Review Website. If you are a member you will be able to log in and view this interactive video lesson.

        1.  A 10-month-old girl was admitted to the hospital for cardiac catheterization. Her history included cyanosis noted at about 6 weeks of age, increasing over the last 7 months and becoming more severe with crying or physical activity. The chest x-ray demonstrates a “boot-shaped heart.” A presumptive diagnosis of tetralogy of Fallot (TOF) was made on admission. TOF has 4 components, which of the following below is NOT PART of the diagnosis?

        A. Pulmonary valve stenosis
        B. VSD
        C. Overriding aorta
        D. Right ventricular hypertrophy
        E. ASD

        Click here to see the answer

        Answer: E, ASD

        In 1888, Fallot described a congenital heart defect composed of four characteristics (a) large ventricular septal defect (VSD) (b) right ventricular outflow obstruction (pulmonary valve stenosis) (c) overriding aorta (d) right ventricular hypertrophy. The main characteristic of TOF is cyanosis. Hypercyanotic spells or “tet spells” are paroxysmal episodes in which the cyanosis acutely worsens. Crying, feeding, or defecating can bring on these episodes.

        Review NCCPA Blueprint Topic: Tetralogy of Fallot

        2. A 65-year-old man presents with pain in his right knee. He says he fell and “banged it up fairly bad” approximately 6 months ago but that it had since recovered spontaneously and provided no further trouble until now. On examination, his temperature is 37.5 °C and his blood pressure is 125/70 mm Hg. He has an inflamed, tender, swollen right knee. No other joints are affected. No other abnormalities are found on physical examination. A plain radiographic examination of the right knee reveals streaking of the surrounding soft tissue with calcium deposits (chondrocalcinosis). What is the definitive diagnostic test of choice for this patient’s disease

        A. A plasma level
        B. A random urine test
        C. A 24-hour urine
        D. A synovial fluid analysis
        E. Gram stain plus culture and sensitivity

        Click here to see the answer

        The answer is D: A synovial fluid analysis

        A definitive diagnosis of gout is made by demonstrating negatively birefringent, needle-shaped monosodium urate crystals under a polarizing microscope. Although an elevated serum uric acid concentration is often seen in acute gout, it is neither as sensitive nor as specific a test as the demonstration of uric acid crystals in the synovial fluid under a microscope.

        Serum uric acid levels can be normal in patients with acute gouty arthritis. The diagnosis of septic arthritis can be ruled out by appropriate Gram stain and culture of the same specimen of synovial fluid obtained for examination with the polarizing microscope.

        Review NCCPA Blueprint Topic: Gout and pseudogout (Lecture)

        3. What is (are) the major difference(s) between polymyalgia rheumatica (PMR) and polymyositis?

        A. Marked proximal muscle weakness in polymyositis
        B. Marked proximal muscle tenderness in polymyositis
        C. Elevated muscle enzymes such as creatine kinase (CK) in polymyositis
        D. a, b, and c

        Click here to see the answer

        The answer is D: a, b, and c

        The differences between Polymyalgia Rheumatica (PMR) and polymyositis on clinical examination are as follows:

        • There is marked weakness associated with proximal muscle pain in polymyositis
        • There is often marked muscle tenderness (versus joint pain in PMR) associated with the proximal muscle pain in polymyositis
        • Laboratory examination reveals elevated muscle enzymes only in polymyositis
        • Polymyositis Pearls

          Polymyositis is an autoimmune-mediated inflammatory destruction of muscles leading to muscle weakness

          • Patients with polymyositis experience proximal symmetric (bilateral) muscle weakness
          • The shoulders and hips are the parts of the body most commonly affected by polymyositis
          • Early fatigue while walking and inability to rise from a seated position
          • Diagnosis

            • The three autoantibodies anti-Jo-1, anti-SRP, and anti-Mi-2, are associated with polymyositis
            • Creatine kinase levels are increased in polymyositis
            • Electromyography can detect regions of dead muscle cells
            • Muscle biopsy can show endomysial inflammation and various stages of necrosis
            • Treatment

              • Initial treatment of polymyositis  involves suppressing the immune response with corticosteroids
              • Methotrexate is used for long-term immunosuppressive therapy in polymyositis
              • Review NCCPA Blueprint Topic: Polymyositis (ReelDx + Lecture)

                4. Clinical features of botulism include all of the following except

                A. Paresthesia
                B. Dysphagia
                C. Diplopia
                D. Fixed/dilated pupils

                Click here to see the answer

                The answer is A: Paresthesia

                Paresthesia is not a feature of botulism while dysphagia, diplopia, and fixed dilated pupils are.

                Botulism Pearls

                • Caused by a neurotoxin elaborated by Clostridium botulinum a gram-positive bacillus, which is an anaerobic, spore-forming bacteria
                • Associated with home-canned food products and honey in infants (wait until babies are at least 12 months before introducing honey)
                • Presents with double vision, drooping of eyelids, inability to make facial expressions, and difficulty swallowing
                • Autonomic nervous system effects may cause dry mouth, postural hypotension, nausea, vomiting, and constipation
                • Can lead to complete flaccid paralysis which is deadly if it involves respiratory muscles
                • In infants, symptoms include constipation and generalized weakness, with weak crying, poor feeding, lethargy, and loss of head control (floppy baby syndrome)
                • Diagnosis

                  • Diagnosis is by toxin assays
                  • Sometimes electromyography
                  • Treatment

                    • Treatment is supportive
                    • The greatest threat to life is respiratory impairment and its complications
                    • IV botulinum immunoglobulin/heptavalent botulinum antitoxin
                    • Correct canning and adequate heating of home-canned food before serving are essential
                    • Canned foods showing evidence of spoilage and swollen or leaking cans should be discarded
                    • Review NCCPA Blueprint Topic: Botulism

                      5. A 59-year-old male complains of “flashing lights behind my eye” followed by a sudden loss of vision, stating that it was “like a curtain across my eye.” He denies trauma. He takes Glucophage for his diabetes mellitus and atenolol for his hypertension. He has no other complaints. On the fundoscopic exam, the retina appears to be out of focus. Which of the following is the most likely diagnosis?

                      A. Central retinal vein occlusion
                      B. Retinal artery occlusion
                      C. Retinal detachment
                      D. Hyphema

                      Click here to see the answer

                      The answer is C: Retinal Detachment

                      Patients with retinal detachment frequently complain of flashes of light or floaters that occur during traction on the retina as it detaches. This is followed by loss of vision. In small detachments, the retina may appear out of focus, but with larger detachments, a retinal fold may be identified.

                      • Central retinal vein and artery occlusion cause painless, variable loss of vision. Exam shows retinal hemorrhages in all quadrants and edema of the optic disk
                      • Hyphema is usually associated with trauma and is a collection of blood in the anterior chamber
                      • Retinal Detachment Pearls

                        • Retinal detachment is a separation of the neurosensory retina from the underlying retinal pigment epithelium
                        • Look for sudden increase or change in floaters along with curtain or veil across the visual field
                        • Often is spontaneous, but may have an underlying cause – example recent cataract surgery
                        • Myopia (nearsightedness) is a risk factor for the development of retinal detachment
                        • Retinal detachment is usually unilateral
                        • Retinal detachment usually presents with defects in the peripheral visual field
                        • Diagnosis

                          • Diagnosis is by fundoscopy – retinal detachment is visualized as crinkling of retinal tissue and changes in vessel direction
                          • Ultrasonography may help determine the presence and type of retinal detachment if it cannot be seen with funduscopy
                          • Treatment

                            • Retinal detachment is an ophthalmologic emergency
                            • Stay supine (lying face upward) with head turned towards the side of the detached retina
                            • Pneumatic retinopexy is a procedure for the management of retinal detachment that involves cryoretinopexy followed by injection of an air bubble in the vitreous
                            • Review NCCPA Blueprint Topic: Retinal detachment (Lecture)

                              6. The first dose of the combined vaccine of measles, mumps, and rubella (MMR) is usually given at age

                              A. 12 months
                              B. 6 weeks
                              C. Birth
                              D. 9 months

                              Click here to see the answer

                              The answer is A: The first dose of MMR is given at age 12 – 15 months and a second dose at age 4-6 years

                              Mumps Pearls

                              Mumps is a viral disease that is part of the paramyxovirus family. It presents with parotitis (painful parotid gland swelling), orchitis, or aseptic meningitis. It is transmitted through respiratory droplets and has an incubation period of 12-14 days

                              • Prodrome of fever, malaise, and anorexia
                              • Parotid enlargement (usually bilateral but not always synchronous) 24 h later
                              • Swelling of submaxillary and submandibular glands
                              • Orchitis (usually unilateral) with testicular enlargement two to three times normal size
                              • Mumps is the most common cause of pancreatitis in children
                              • Diagnosis

                                • During an outbreak, a diagnosis can be made by determining recent exposure and parotitis. Usually, the disease is diagnosed on clinical grounds, and no confirmatory laboratory testing is needed
                                • If there is uncertainty about the diagnosis, a test of saliva or blood may be carried out; a newer diagnostic confirmation, using real-time nested (PCR) technology, has also been developed
                                • As with any inflammation of the salivary glands, the serum level of the enzyme amylase is often elevated
                                • CSF demonstrates increased lymphocytes and decreased glucose 
                                • Treatment

                                  • There is no available cure for mumps and treatment is supportive
                                  • Symptoms usually last for 7-10 days and patients are contagious for up to 9 days after onset
                                  • May need to provide scrotal support if painful or swollen testicle (as in case presentation)
                                  • MMR vaccine is given at 12-15 months then again at 4-6 years of age
                                  • Review NCCPA Blueprint Topic: Mumps

                                    7. A 28-year old sub-fertile woman presents to you on account of dysmenorrhea, deep dyspareunia, dyschezia, and pelvic pain of a few months’ duration. Physical examination revealed nodularity of the uterosacral ligaments, tenderness in the pouch of Douglas, and a fixed retroverted uterus with positive cervical excitation tenderness. What is the most likely diagnosis?

                                    A. Endometriosis
                                    B. Pelvic inflammatory disease
                                    C. Adenomyosis
                                    D. Uterine leiomyoma

                                    The diagnosis is generally made by

                                    A. Detection of increased estrogen levels
                                    B. Endometrial biopsy
                                    C. Pelvic ultrasound
                                    D. Laparoscopy
                                    E. CT of the pelvis

                                    Click here to see the answer

                                    Answer: A, endometriosis, and D Laparoscopy

                                    • Endometriosis, which is the presence of benign endometrial tissue outside of the uterine cavity typically presents as described in this clinical vignette. Remember the “three d’s” – Dyspareunia, dyschezia (difficulty in defecating) and dysmenorrhea
                                    • Definitive diagnosis is made by laparoscopy and confirmed with a biopsy
                                    • Imaging tests (eg, ultrasonography, barium enema, IV urography, CT, MRI) are not specific or adequate for diagnosis. However, they sometimes show the extent of endometriosis and thus can be used to monitor the disorder once it is diagnosed.
                                    • Incorrect Answers:

                                      • Patients with PID may have similar symptoms with endometriosis, but also presents with fever and vaginal discharge
                                      • Patients with adenomyosis (a condition in which endometrial tissue exists within and grows into the uterine wall) present with uterine mass with or without pressure symptoms and menorrhagia
                                      • Uterine leiomyomas cause chronic painful bleeding and are common in women in their late thirties and early forties.
                                      • Review NCCPA Blueprint Topic: Endometriosis (Lecture)

                                        8. A 45-year-old obese Caucasian gentleman arrives at your clinic for a routine check-up after having some blood work done during a workplace health screening. He is found to have an LDL cholesterol level of 550 mg/dL. He states that his father and brother had high cholesterol and both died at a young age from a heart attack. He has a follow-up appointment with his cardiologist because of some occasional chest pain and abnormalities seen on his EKG. Additionally, you notice that he has well-demarcated yellow deposits around his eyes. He is started on high dose statin and his LDL at 12 weeks is 350 mg/dL. What is the next best step in this patient’s management?

                                        A. Continue high dose statin, the patient’s LDL is at goal
                                        B. Add niacin 100 mg three times daily
                                        C. Add ezetimibe (Zetia) 10 mg daily
                                        D. Add a PCSK9 inhibitor
                                        E. Refer to a lipid specialist

                                        Click here to see the answer

                                        The answer is C: add ezetimibe 10 mg

                                        If LDL-C is not at goal after 6-12 weeks the next best step for the treatment of familial hypercholesterolemia is to add ezetimibe 10 mg daily and check again in 6-12 weeks. If at that time the patient’s LDL is still not at goal (ideally < 150) refer to lipid specialist to consider adding a PCSK9 inhibitor.

                                        Pearls

                                        • Familial hypercholesterolemia (FH) is the most common autosomal dominant genetic disease. The clinical syndrome (phenotype) is characterized by extremely elevated levels of low-density lipoprotein cholesterol (LDL-C) and a propensity to early-onset atherosclerotic cardiovascular disease. In general, homozygotes manifest the disease at a much earlier age than heterozygotes and the disease is more severe.
                                        • Homozygous FH patients are rare and have an estimated prevalence of approximately 1:300,000 to 1:400,000
                                        • Heterozygous FH is estimated to occur in 1 in 200 to 250 individuals in the United States.
                                        • It is estimated that about 7 percent of American adults have an untreated lipoprotein cholesterol ≥190 mg/dL but only 1.7 percent carry an FH mutation
                                        • Patients with undiagnosed homozygous familial hypercholesterolemia (FH) develop severe, premature, atherosclerotic cardiovascular disease and die before age 20 in many cases.
                                        • In patients with a negative or unknown family history, an untreated LDL-C level of ≥190 mg/dL (4.9 mmol/L) suggests FH. This value is greater than the 90th percentile for age and sex.
                                        • Diagnosis

                                          • The diagnosis of heterozygous familial hypercholesterolemia (FH) is made with genetic testing or clinical criteria. A causative mutation in the LDLR, APOB, or PCSK9 gene(s) secures this diagnosis
                                          • When genetic testing is not available or not felt to be necessary, you can use the Dutch Lipid Clinic Network criteria, which assigns points based on low-density lipoprotein cholesterol (LDL-C) levels, personal history of early atherosclerotic cardiovascular disease (ASCVD), family history of early ASCVD, or high cholesterol in a first-degree relative, and personal and physical examination finding
                                          • Treatment

                                            • Patients with homozygous familial hypercholesterolemia (FH) – intensive LDL-C lowering, which targets a minimal value of <150 mg/dL (3.9 mmol/L)
                                            • In addition to a high-dose statin (atorvastatin 80 mg daily or rosuvastatin 40 mg daily), most homozygous patients will require additional therapies such as ezetimibe, a PCSK9 inhibitor, or potentially LDL-C apheresis
                                            • Review NCCPA Blueprint Topic: Hypercholesterolemia

                                              9. What best describes the time that preeclampsia is commonly seen?

                                              A. Before 18 weeks of pregnancy
                                              B. After 18 weeks of pregnancy
                                              C. After 16 weeks of pregnancy
                                              D. After 20 weeks of pregnancy
                                              E. Before 12 weeks of pregnancy

                                              Click here to see the answer

                                              The answer is D, after 20 weeks of pregnancy

                                              Preeclampsia is a systemic disease characterized by hypertension that is accompanied by proteinuria. Preeclampsia usually begins after the 20th week of gestation; however, it can appear at any time during pregnancy. It occurs most frequently in the final trimester.

                                              Pearls

                                              • Preeclampsia is a systemic disease characterized by hypertension that is accompanied by proteinuria after the 20th week of gestation.
                                              • If left untreated, preeclampsia can lead to serious, and even fatal, complications.
                                              • Risk factors include nulliparity, age younger than 19 or older than 35, obesity, multiple gestations, positive family history, pre-existing hypertension or renal disease, and diabetes mellitus.
                                              • Eclampsia is defined as the development of seizures in a woman with preeclampsia.
                                              • Diagnosis

                                                • Hypertension with proteinuria
                                                • Mild Preeclampsia
                                                  • BP 140/90 – 160/110
                                                  • Proteinuria – > 300 mg/24 hours or > +1 on dipstick
                                                  • BP > 160/110
                                                    • Proteinuria > 5g in 24 hours or no urine or 3 +on dipstick
                                                    • ***HELLP SYNDROME – Hemolysis, elevated liver enzymes, and low platelets
                                                    • Treatment

                                                      • Delivery is the only cure for preeclampsia. The decision to induce depends on the stage of pregnancy and the severity of the disease
                                                      • Patients with preeclampsia without severe symptoms are generally induced into labor after 37 weeks gestation in severe preeclampsia delivery is performed at 24-26 weeks
                                                      • If less than 34 weeks antenatal steroids promote fetal lung development
                                                      • Intravenous magnesium sulfate as seizure prophylaxis)
                                                      • Review NCCPA Blueprint Topic: PANCE Blueprint Reproductive System (7%) ⇒ Hypertension disorders in pregnancy

                                                        10. A 36-year-old male who is hospitalized because of severe injuries from a motor vehicle accident develops a rapid onset of profound dyspnea. The initial chest x-ray shows a normal heart size with diffuse bilateral infiltrates. A follow-up chest x-ray shows confluent bilateral infiltrates that spare the costophrenic angles. Which of the following is the best clinical intervention for this patient?

                                                        A. Tracheal intubation
                                                        B. Bilateral chest tube insertion
                                                        C. Type-specific packed cells
                                                        D. Colloid solutions
                                                        E. Provide supplemental oxygen

                                                        Click here to see the answer

                                                        The answer is A – Tracheal intubation

                                                        Tracheal intubation with the lowest level of PEEP is required to maintain the PaO2 above 60 mmHg or SaO2 above 90% in a patient with ARDS

                                                        Pearls

                                                        Acute respiratory distress syndrome (ARDS) is a type of respiratory failure characterized by fluid collecting in the lungs depriving organs of oxygen

                                                        • The underlying abnormality in ARDS is ⇑ Permeability of alveolar-capillary membranes ⇒ development of protein-rich pulmonary edema (non-cardiogenic pulmonary edema)
                                                        • ARDS can occur in those who are critically ill or who have significant injuries
                                                        • Three clinical settings account for 75% of ARDS cases:

                                                          • Sepsis syndrome (most common cause)
                                                          • Severe multiple trauma
                                                          • Aspiration of gastric contents (alcoholics), toxic inhalation, near-drowning
                                                          • People with ARDS have severe shortness of breath and often are unable to breathe on their own without support from a ventilator

                                                            • Occurring 12-24 hours after the precipitating event
                                                            • Tachypnea, pink frothy sputum, crackles
                                                            • Diagnosis

                                                              Chest radiograph shows air bronchograms and bilaterally fluffy infiltrate

                                                              • Normal BNP, pulmonary wedge pressure, left ventricle function and echocardiogram
                                                              • Treatment

                                                                • Treatment involves identifying and managing underlying precipitation and secondary conditions
                                                                • Tracheal intubation with the lowest level PEEP to maintain PaO2 >60 mmHg or SaO2 >90
                                                                • ARDS is often fatal, the risk increases with age and severity of illness
                                                                • Review NCCPA Blueprint Topic: PANCE Blueprint Pulmonary (10%) ⇒ Acute respiratory distress syndrome (Lecture)

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                                                                      31 min
                                                                    5. Podcast Episode 75: Ten FREE PANCE and PANRE Audio Board Review Questions

                                                                      Welcome to episode 75 of the Audio PANCE and PANRE PA Board Review Podcast.

                                                                      Join me as I cover ten PANCE and PANRE Board review questions from the SMARTYPANCE course content following the NCCPA™ content blueprint (download the FREE cheat sheet).

                                                                      This week we will be covering ten general board review questions based on the NCCPA PANCE and PANRE Content Blueprints. 

                                                                      Below you will find an interactive exam to complement the podcast.

                                                                      The Audio PANCE and PANRE Physician Assistant Board Review Podcast

                                                                      I hope you enjoy this free audio component to the examination portion of this site. The full board review includes over 2,000 interactive board review questions and is available to all members of the PANCE and PANRE Academy and Smarty PANCE.

                                                                      • You can download and listen to past FREE episodes here, on iTunes, on Google Play Music or Stitcher Radio.
                                                                      • You can listen to the latest episode, take an interactive quiz and download your results below.
                                                                      • Listen Carefully Then Take The Practice Exam

                                                                        If you can’t see the audio player click here to listen to the full episode.

                                                                        Podcast Episode 75: Ten Question PANCE and PANRE Podcast Quiz

                                                                        The following questions are linked to NCCPA Content Blueprint lessons from the Smarty PANCE and PANRE Board Review Website. If you are a member you will be able to log in and view this interactive video lesson.

                                                                        1. A 5-year-old girl is brought to the emergency department after drinking a bottle of drain cleaner. It is unknown how much the child drank. She has a past medical history of Down syndrome and obesity. The patient’s vitals are unremarkable. Physical exam is notable for a child in no acute distress. She is tolerating her oral secretions and is interactive. Inspection of the oropharynx is unremarkable. Which of the following is the appropriate management of this patient?

                                                                        1. Dilute hydrochloric acid
                                                                        2. Endoscopy
                                                                        3. Intubation
                                                                        4. Observation
                                                                        5. Polyethylene glycol
                                                                        6. Click here to see the answer

                                                                          Answer: B. Endoscopy 

                                                                          Ingestion of caustic fluids (acid or alkali) such as drain cleaner may lead to esophageal damage and stricture. Any patient presenting after caustic ingestion should have an endoscopy performed between 12 and 24 hours of presentation. Injury due to ingestion of alkaline fluids such as drain/oven cleaner occurs rapidly in the first minutes to hours and is characterized by liquefactive necrosis of the esophageal tissue. Subsequently, esophageal strictures form due to scarring of the affected tissue. Patients should immediately be resuscitated following the ABC’s (airway, breathing, and circulation). Subsequent management involves endoscopy (typically within 12 to 24 hours of ingestion) to assess the extent of the damage and plan any further treatment that may be needed.

                                                                          Incorrect Answers:

                                                                          • Answer 1: Dilute hydrochloric acid or administration of any agent to titrate the ingestion is always contraindicated as this will lead to more tissue damage.
                                                                          • Answer 3: Intubation would be indicated if the patient was failing to protect their airway or if they had impending airway loss. This well-appearing patient has no airway concerns.
                                                                          • Answer 4: Observation is certainly a part of this patient’s care; however, she must also receive endoscopy to assess for any esophageal/GI tract injury.
                                                                          • Answer 5: Polyethylene glycol or whole bowel irrigation has limited indications. It may be used to pass bags of drugs if ingested by a packer/stuffer but would not aid in the management of caustic ingestion.
                                                                          • Review NCCPA Blueprint Topic: Ingestion of toxic substances or foreign bodies

                                                                            2. A 27-year-old man presents to the emergency department after a motor vehicle collision. The patient was a front seat unrestrained driver in a head-on collision. The patient’s echocardiogram (ECG) is notable only for sinus tachycardia. His temperature is 99.5°F (37.5°C), blood pressure is 107/58 mmHg, pulse is 120/min, respirations are 17/min, and oxygen saturation is 98% on room air. The patient is given 2 liters of Ringer lactate solution and morphine. Initial workup demonstrates that the patient’s pulmonary capillary wedge pressure and troponins are elevated. The patient is currently complaining of chest pain. Physical exam is notable for an uncomfortable young man with bruising over his chest wall. Which of the following is the most likely diagnosis?

                                                                            1. Cardiac contusion
                                                                            2. Hemorrhage
                                                                            3. Myocardial infarction
                                                                            4. Pulmonary contusion
                                                                            5. Takotsubo cardiomyopathy
                                                                            6. Click here to see the answer

                                                                              Answer: A. Cardiac contusion

                                                                              This patient is presenting after blunt chest trauma (which is common in motor vehicle accidents) with chest pain, elevated troponins, and an elevated pulmonary capillary wedge pressure suggesting a diagnosis of a cardiac contusion. A cardiac contusion is a blunt injury to the heart which can disrupt the mechanical and electrical function of the heart. There will typically be visible signs of chest trauma such as bruising and the patient will often complain of chest pain and dyspnea. The ECG can be unremarkable, demonstrate sinus tachycardia, or even demonstrate more severe dysrhythmias such as supraventricular tachycardia, atrial fibrillation, and a right bundle branch block. Initial cardiac troponins can be elevated. In the setting of any ECG abnormality or elevated troponins, patients with a suspected diagnosis of a cardiac contusion should be admitted to the hospital and observed until clinically stable with normalization of their troponins.

                                                                              Incorrect Answers:

                                                                              • Answer 2: Hemorrhage would present with hypotension, tachycardia, and a decreased pulmonary capillary wedge pressure. Internal bleeding could be assessed with a FAST exam which assesses for pleural sliding, pericardial fluid and cardiac function, fluid in the hepatorenal and splenorenal recesses, and fluid surrounding the bladder.
                                                                              • Answer 3: Myocardial infarction presents with chest pain, shortness of breath, ST elevation on ECG and elevated cardiac troponins. This patient’s elevated troponins are likely secondary to blunt trauma to the heart as he has no risk factors for ischemic heart disease and is young.
                                                                              • Answer 4: Pulmonary contusion presents with chest pain, hypoxia, and patchy opacities on chest radiography which may not be initially apparent. Management for a pulmonary contusion is typically supportive in nature and to adequately control the patient’s pain.
                                                                              • Answer 5: Takotsubo cardiomyopathy presents with chest pain and dyspnea as well as ST elevation on ECG without reciprocal changes. Global hypokinesis of the heart can be seen on echocardiography and minor elevations in troponins can be present. The typical precipitating event for Takotsubo cardiomyopathy is an emotionally stressful life event and the patient is typically a woman in contrast to this male patient who has a mechanism of injury that supports a diagnosis of a cardiac contusion.
                                                                              • Review NCCPA Blueprint Topic: Chest/Rib Fractures and Trauma

                                                                                3. A 33-year-old woman presents to her primary care PA for a wellness check-up. She states that recently she has been feeling well other than headaches that occur occasionally, which improve with ibuprofen and rest. She has a past medical history of hypertension and headaches and is currently taking hydrochlorothiazide. Her temperature is 99.2°F (37.3°C), blood pressure is 157/108 mmHg, pulse is 90/min, respirations are 14/min, and oxygen saturation is 98% on room air. Physical exam reveals a young woman who appears healthy. A normal S1 and S2 are auscultated on cardiac exam, and her lungs are clear with good air movement bilaterally. From her previous visit, it was determined that she has an elevated aldosterone and low renin level. Laboratory values are ordered as seen below.

                                                                                Serum:
                                                                                Na+: 139 mEq/L
                                                                                Cl-: 100 mEq/L
                                                                                K+: 3.7 mEq/L
                                                                                HCO3-: 29 mEq/L
                                                                                BUN: 20 mg/dL
                                                                                Creatinine: 1.1 mg/dL

                                                                                Which of the following is the most likely diagnosis?

                                                                                1. Benign essential hypertension
                                                                                2. Cushing syndrome
                                                                                3. Narrowing of the renal arteries
                                                                                4. Pheochromocytoma
                                                                                5. Primary hyperaldosteronism
                                                                                6. Click here to see the answer

                                                                                  Answer: E. Primary hyperaldosteronism

                                                                                  This patient is presenting with hypertension refractory to a diuretic with a decreased potassium, a decreased renin level, and an increased aldosterone level suggesting a diagnosis of primary hyperaldosteronism.

                                                                                  Primary hyperaldosteronism occurs when the adrenal gland produces excess aldosterone. Aldosterone has the effect in the kidney of absorbing sodium (and thus water) and wasting potassium and hydrogen. Thus, hyperaldosteronism can lead to hypertension, hypokalemia, and a metabolic alkalosis. In primary hyperaldosteronism, the high blood pressure is detected by the kidney, and thus renin levels are decreased in the setting of an elevated aldosterone.

                                                                                  Incorrect Answers:

                                                                                  • Answer 1: Benign essential hypertension typically occurs in overweight patients and has no clear underlying cause. It would not be associated with elevated aldosterone levels.
                                                                                  • Answer 2: Cushing syndrome would be associated with weight gain, limb muscle atrophy, and striae on dermatological exam in the setting of a decreased renin and aldosterone.
                                                                                  • Answer 3: Narrowing of the renal arteries (renal artery stenosis) would present with refractory hypertension in the setting of an elevated renin and aldosterone level.
                                                                                  • Answer 4: Pheochromocytoma would present with severe episodic hypertension and headaches secondary to an adrenal mass that releases catecholamines.
                                                                                  • Summary: Primary hyperaldosteronism presents with hypertension, a decreased renin and potassium level, a metabolic alkalosis, and an increased aldosterone level.

                                                                                    Review NCCPA Blueprint Topic: Secondary hypertension

                                                                                    4. A 24-year-old man is brought in to the emergency room after being retrieved by firefighters from a burning building. The patient is responding coherently to questions but reports pain secondary to a burn on his leg. He states he also has a headache and feels dizzy. His temperature is 98.5°F (36.9°C), blood pressure is 129/66 mmHg, pulse is 126/min, respirations are 14/min, and oxygen saturation is 99% on room air. Physical exam is notable for a confused young man with dry and flushed skin. The cardiopulmonary exam reveals a normal S1 and S2, as well as clear breath sounds bilaterally. The patient’s neurological exam is within normal limits. Towards the end of his exam, the patient begins vomiting. The dermatologic exam reveals a superficial burn covering 1% of the patient’s body over his right leg. Which of the following is the best next step in management for this patient?

                                                                                    1. 100% oxygen
                                                                                    2. CT scan of the head
                                                                                    3. Hydroxocobalamin
                                                                                    4. Normal saline
                                                                                    5. Ondansetron
                                                                                    6. Click here to see the answer

                                                                                      Answer: A. 100% oxygen

                                                                                      This patient is presenting after being rescued from a fire with confusion, headache, nausea, vomiting, and flushed skin suggesting a diagnosis of carbon monoxide poisoning which should be treated with 100% oxygen.

                                                                                      Carbon monoxide exposure is common in fires and in patients who heat their house with an old-fashioned wood stove. Carbon monoxide binds to hemoglobin with a higher affinity than oxygen thus displacing it leading to symptoms. Carbon monoxide poisoning presents with confusion, headache, altered mental status, nausea, vomiting, and cherry-red skin. Pulse oximetry is often normal in these patients as the device detects hemoglobin bound to oxygen or carbon monoxide similarly. A carboxyhemoglobin level can be obtained to confirm the diagnosis in these patients; however, patients presenting with a clinical picture supportive of carbon monoxide poisoning should be treated with 100% (or hyperbaric) oxygen. Sequelae of carbon monoxide poisoning should be treated supportively, including dantrolene for increased muscle activity or benzodiazepines for seizure activity.

                                                                                      Incorrect Answers:

                                                                                      • Answer 2: CT scan of the head would be indicated if a patient presented with head trauma followed by altered mental status, nausea, and vomiting. This patient’s neurological abnormalities, as well as his nausea and vomiting, can be explained by his carbon monoxide poisoning.
                                                                                      • Answer 3: Hydroxocobalamin is the treatment of choice for cyanide poisoning which is also associated with exposure to fires. Patients will present with weakness, malaise, headache, dizziness, nausea, vomiting, and shortness of breath. Though this diagnosis is possible in this patient, a more likely diagnosis both epidemiologically and given his flushed skin is carbon monoxide poisoning. This patient will need empiric treatment for cyanide poisoning, however, a more dire intervention for the most likely diagnosis is putting the patient on oxygen to simultaneously and rapidly improve his respiratory status and treat his carbon monoxide poisoning.
                                                                                      • Answer 4: Normal saline may be necessary to stabilize this patient’s blood pressure; however, his tachycardia is likely secondary to his pain and a more important initial intervention is stabilizing the patient’s respiratory status including administering oxygen for this patient’s carbon monoxide poisoning.
                                                                                      • Answer 5: Ondansetron only treats this patient’s symptoms of nausea but does not address their respiratory status which should be treated promptly and prior to treating other concerns.
                                                                                      • Summary: The treatment of carbon monoxide poisoning is 100% oxygen.

                                                                                        Review NCCPA Blueprint Topic: Burns (ReelDx)

                                                                                        5. A 42-year-old woman is brought to the emergency department after a motor vehicle accident. She complains of lower back pain and some minor abdominal pain. The patient has a past medical history of obesity and type II diabetes. Her current medications include atorvastatin, metformin, and glyburide. A FAST exam is performed in the trauma bay and does not reveal any signs of intra-abdominal bleeding. Her temperature is 98.2°F (36.8°C), blood pressure is 130/77 mmHg, pulse is 90/min, respirations are 16/min, and oxygen saturation is 99% on room air. Ultrasound findings are notable for multiple gallstones in the gallbladder. The patient is given naproxen. Which of the following is the best next step in management?

                                                                                        1. CT scan of the abdomen
                                                                                        2. NPO, IV fluids, and broad-spectrum antibiotics
                                                                                        3. Perform a cholecystectomy this hospital visit
                                                                                        4. Schedule an outpatient cholecystectomy
                                                                                        5. Supportive therapy
                                                                                        6. Click here to see the answer

                                                                                          Answer: E. Supportive therapy

                                                                                          This patient is presenting with asymptomatic gallstones discovered incidentally. Asymptomatic gallstones do not need to be managed with a cholecystectomy. 

                                                                                          Acute cholecystitis classically presents with right upper quadrant abdominal pain that presents in a fat, fertile, female in her forties. Once the diagnosis is confirmed with ultrasound, “cooling off” of the gallbladder is necessary (keeping the patient NPO and IV fluids) followed by a cholecystectomy that hospital visit. However, if asymptomatic gallstones are discovered incidentally, there is no indication for cholecystectomy. These patients should be managed conservatively.

                                                                                          Incorrect Answers:

                                                                                          • Answer 1: CT scan of the abdomen is unnecessary as there is no indication to perform a CT scan, in particular when the only finding in this assessment was asymptomatic gallstones on ultrasound. 
                                                                                          • Answer 2: NPO, IV fluids, and broad spectrum antibiotics is the best initial management of ascending cholangitis. Patients with ascending cholangitis are acutely ill and present with a fever, jaundice, and right upper quadrant tenderness. They require immediate treatment as well as decompression (from interventional radiology), followed by ERCP/cholecystectomy. 
                                                                                          • Answer 3: Performing a cholecystectomy this hospital visit is the appropriate management of acute cholecystitis. Acute cholecystitis would present with right upper quadrant abdominal pain in an overweight woman after eating a fatty meal. It is not indicated in the management of asymptomatic gallstones. 
                                                                                          • Answer 4: Scheduling an outpatient cholecystectomy is not necessary as this patient is asymptomatic. Outpatient cholecystectomies are not typically performed in the management of acute cholecystitis as most patients do not comply with outpatient recommendations (avoiding triggers like fatty foods and alcohol) and end up returning to the hospital for another flare before their procedure. In certain compliant patients, it may be a viable option.
                                                                                          • Review NCCPA Blueprint Topic: Cholelithiasis (ReelDx + Lecture)

                                                                                            6. A 60-year-old woman presents to the emergency department with dizziness. She states it started this morning when she woke up from bed and was severe causing her to vomit. The episode resolved in 1 minute. The patient has a past medical history of hypertension, diabetes, obesity, and atrial fibrillation treated with warfarin and metoprolol. She recently recovered from a cold a few days ago. Her temperature is 99.0°F (37.2°C), blood pressure is 174/99 mmHg, pulse is 115/min, respirations are 12/min, and oxygen saturation is 98% on room air. Physical exam is notable for a well-appearing woman. Her neurological exam including cranial nerves and gait is within normal limits. The patient is laid flat in the bed which causes an episode of dizziness with notable nystagmus and vomiting. She feels better after 1 minute. The patient’s ECG is within normal limits. Lab values are notable for an INR of 3.5. Which of the following is the most likely etiology of this patient’s symptoms?

                                                                                            1. Canalithiasis
                                                                                            2. Increased endolymph production
                                                                                            3. Inflammation of the vestibular apparatus
                                                                                            4. Inflammation of the vestibulocochlear apparatus
                                                                                            5. Vertebrobasilar insufficiency
                                                                                            6. Click here to see the answer

                                                                                              Answer: A. Canalithiasis

                                                                                              This patient is presenting with intermittent, severe vertigo which is provoked by position changes which is most consistent with benign paroxysmal positional vertigo (BPPV). BPPV is commonly caused by canalithiasis.

                                                                                              Benign paroxysmal positional vertigo (BPPV) is a common form of peripheral vertigo that results from a dislodged piece of otolith (called otoconia when dislodged) causing disturbances in the semicircular canals. The presentation of BPPV involves sudden and episodic vertigo with head movements that lasts for seconds to minutes accompanied by nausea and vomiting. Physical exam will demonstrate a horizontal nystagmus with specific head postures (such as the Dix-Hallpike maneuver). Treatment involves repositioning exercises (such as the Epley maneuver) as well as meclizine or diphenhydramine for symptomatic control.

                                                                                              Incorrect Answers:

                                                                                              • Answer 2: Increased endolymph production describes Meniere disease which presents with chronic symptoms including hearing loss and ear fullness and intermittent episodes of vertigo. Treatment involves diuretics and salt restriction.
                                                                                              • Answers 3-4: Inflammation of the vestibular apparatus and the vestibulocochlear apparatus describes vestibular neuritis (sustained/persistent vertigo after a cold) and labyrinthitis (sustained/persistent vertigo and hearing loss after a cold), respectively. This condition will resolve on its own; however, symptoms can be treated with meclizine or diphenhydramine.
                                                                                              • Answer 5: Vertebrobasilar insufficiency can present with syncope or if there is a hemorrhage/ischemia, may present in an elderly patient with multiple risk factors with sustained and severe vertigo that is sudden onset and associated with dysarthria and dystonia.
                                                                                              • Summary: Benign paroxysmal positional vertigo is commonly caused by canalithiasis.

                                                                                                Review NCCPA Blueprint Topic: Vertigo (ReelDx + Lecture)

                                                                                                7. An 18-year-old male presents to his primary care provider with his parents for a sports physical. He was last seen in the clinic several months ago when he was diagnosed with attention deficit hyperactivity disorder (ADHD). He was started on methylphenidate at that time, and the patient now reports improvement in his ability to concentrate in school and at home. He hopes to play baseball in college and has begun lifting weights daily in preparation for baseball season. The patient reports that he eats a healthy diet to fuel his exercise regimen. His parents have no concerns and are pleased with the recent improvement in his grades. On physical exam, the patient has tall stature with average muscle mass for his age. He has no dysmorphic features. His chest has a normal appearance other than mild gynecomastia. The patient has sparse facial hair and a moderate amount of coarse pubic hair that extends across the pubis and spares the medial thighs. His testes are small and firm. Due to the latter, laboratory testing is performed and reveals the following:

                                                                                                • Follicle-stimulating hormone (FSH): 42 mIU/mL (Reference range: 4-25 mIU/mL)
                                                                                                • Luteinizing hormone (LH): 38 mIU/mL (Reference range: 6-23 mIU/mL)
                                                                                                • Which of the following is the most likely etiology of this patient’s presentation?

                                                                                                  1. Anabolic steroid use
                                                                                                  2. CGG trinucleotide repeat disorder
                                                                                                  3. CTG trinucleotide repeat disorder
                                                                                                  4. Failure of neuronal migration
                                                                                                  5. Meiotic nondisjunction
                                                                                                  6. Click here to see the answer

                                                                                                    Answer: E. Meiotic nondisjunction

                                                                                                    This patient presents with tall stature, gynecomastia, and small testes with elevated FSH and LH, which suggests a diagnosis of Klinefelter syndrome. Klinefelter syndrome is usually caused by meiotic nondisjunction that results in a 47,XXY genotype.

                                                                                                    Klinefelter syndrome is the most common cause of primary hypogonadism. Patients with Klinefelter syndrome present with tall stature, neurocognitive difficulties (ADHD) and features of hypogonadism including gynecomastia, small testes, small phallus, hypospadias, underdeveloped secondary sex characteristics, and cryptorchidism. Patients without hypospadias or cryptorchidism are often not diagnosed until after puberty, when the symptoms of gynecomastia and small testes become more prominent. Because the hypogonadism in Klinefelter syndrome is caused by testicular fibrosis, laboratory results demonstrate a low testosterone and elevated FSH and LH.

                                                                                                    Incorrect Answers:

                                                                                                    • Answer 1: Anabolic steroid use causes decreased levels of FSH and LH due to the suppression of GnRH release by the hypothalamus, which in turn suppresses FSH and LH release by the pituitary gland. Anabolic steroid use would not present with signs of hypogonadism.
                                                                                                    • Answer 2: The CGG trinucleotide repeat disorder characterizes Fragile X syndrome. Fragile X presents with macroorchidism rather than hypogonadism, and patients typically have dysmorphic features of a long, narrow face with large ears, prominent forehead, and prominent chin. Fragile X is the most common cause of inherited intellectual disability.
                                                                                                    • Answer 3: The CTG trinucleotide repeat disorder characterizes myotonic dystrophy. Although myotonic dystrophy presents with hypogonadism, patients would also present with symptoms of progressive weakness, such as facial weakness, dysphagia, or hand grip weakness.
                                                                                                    • Answer 4: Failure of neuronal migration characterizes Kallmann syndrome. Kallmann syndrome presents with the classic symptoms of loss of smell and hypogonadism, but patients with Kallmann syndrome have a low FSH and LH.
                                                                                                    • Summary: Klinefelter syndrome results in primary hypogonadism and presents with tall stature, gynecomastia, small testes, a small phallus, hypospadias, and cryptorchidism.

                                                                                                      Review NCCPA Blueprint Topic: Hypogonadism

                                                                                                      8. A 65-year-old man presents to the emergency department for sudden weakness. The patient states that he was at home enjoying his morning coffee when his symptoms began. He says that his left arm suddenly felt very odd and weak thus prompting him to come to the ED. The patient has a past medical history of diabetes, COPD, hypertension, anxiety, alcohol abuse, and PTSD. He recently fell off a horse while horseback riding but claims to not have experienced any significant injuries. He typically drinks 5-7 drinks per day and his last drink was yesterday afternoon. His current medications include insulin, metformin, atorvastatin, lisinopril, albuterol, and fluoxetine. His temperature is 99.5°F (37.5°C), blood pressure is 177/118 mmHg, pulse is 120/min, respirations are 18/min, and oxygen saturation is 93% on room air. On physical exam, you note an elderly man who is mildly confused. The cardiopulmonary exam demonstrates bilateral expiratory wheezes and a systolic murmur along the right upper sternal border that radiates to the carotids. Neurological exam reveals cranial nerves II-XII as grossly intact with finger-nose exam mildly abnormal on the left and heel-shin exam within normal limits. The patient has 5/5 strength in his right arm and 3/5 strength in his left arm. The patient struggles to manipulate objects such as a pen with his left hand. The patient is given a dose of diazepam and started on IV fluids. Which of the following is the most likely diagnosis in this patient?

                                                                                                      1. Berry aneurysm rupture
                                                                                                      2. Bridging vein tear
                                                                                                      3. Cerebellar bleeding
                                                                                                      4. Hypertensive encephalopathy
                                                                                                      5. Lacunar stroke
                                                                                                      6. Click here to see the answer

                                                                                                        Answer: E. Lacunar stroke

                                                                                                        This patient is presenting with risk factors and symptoms suggestive of a diagnosis of a lacunar stroke. 

                                                                                                        Lacunar strokes typically occur in patients with risk factors such as hypertension, diabetes, old age, and smoking. The basal ganglia, pons, and subcortical white matter are commonly affected. The pathophysiology occurs secondary to a small penetrating artery occlusion from hypertensive arteriolar sclerosis, lipohyalinosis, or microatheroma formation. Patients present with neurological deficits that can include pure motor hemiparesis, pure sensory stroke, ataxic hemiparesis, or dysarthria-clumsy hand syndrome.

                                                                                                        Incorrect Answers:

                                                                                                        • Answer 1: Berry aneurysm rupture describes a subarachnoid hemorrhage that would present with a sudden onset, severe headache.
                                                                                                        • Answer 2: Bridging vein tear describes a subdural hematoma which could present with gradual neurological deficits and altered cognition in the setting of recent trauma in an elderly patient/alcoholic.
                                                                                                        • Answer 3: Cerebellar bleeding would present with ataxic gait and an abnormal finger-nose and heel-shin exam.
                                                                                                        • Answer 4: Hypertensive encephalopathy presents with general CNS dysfunction which can include headache, irritability, nausea/vomiting, disturbances of consciousness, and seizures.
                                                                                                        • Review NCCPA Blueprint Topic: Stroke (ReelDx + Lecture)

                                                                                                          9. A 26-year-old woman presents to the emergency department with abdominal pain. She states that she was walking up the stairs at work when she felt sudden and severe abdominal pain followed by nausea and vomiting. Her past medical history is noncontributory and she is not currently taking any medications. Her temperature is 99.7°F (37.6°C), blood pressure is 122/78 mmHg, pulse is 120/min, respirations are 17/min, and oxygen saturation is 98% on room air. Physical exam is notable for an absence of abdominal tenderness, a left adnexal mass, and left adnexal tenderness. A transvaginal ultrasound demonstrates free fluid surrounding the ovary with edema and the presence of doppler flow. A urinary pregnancy test is negative. The patient’s symptoms persisted after ibuprofen and acetaminophen. Which of the following is the best next step in management?

                                                                                                          1. CT scan of the abdomen
                                                                                                          2. Laparoscopy
                                                                                                          3. Laparotomy
                                                                                                          4. MRI of the pelvis
                                                                                                          5. Observation and serial abdominal exams
                                                                                                          6. Click here to see the answer

                                                                                                            Answer: B. Laparoscopy

                                                                                                            This patient is presenting with sudden onset abdominal pain, nausea, vomiting, and free fluid around the ovary with normal blood flow which is still concerning for ovarian torsion that should be managed with laparoscopy. Ovarian torsion occurs when the ovary twists around its blood supply causing ischemia and necrosis. Patients are typically young women who experience sudden/severe abdominal or vaginal pain, blood per vagina, a left adnexal mass with adnexal tenderness, and a negative urine pregnancy test. The best initial test is a transvaginal ultrasound with Doppler which can show blood flow to the ovary as well as ovarian enlargement and edema (signs of ischemia). Even in the setting of normal blood flow, torsion is possible as the ovary may twist and untwist. Patients presenting with symptoms concerning for ovarian torsion should be managed with laparoscopy to definitively treat and salvage the ovary.

                                                                                                            Incorrect Answers:

                                                                                                            • Answer 1: CT scan of the abdomen would not be necessary as this patient has no abdominal tenderness and has physical exam and ultrasound findings concerning for ovarian torsion which should be managed surgically. 
                                                                                                            • Answer 3: Laparotomy is an open procedure that would be indicated if the patient suddenly decompensated and needed more aggressive management to stop acute bleeding. 
                                                                                                            • Answer 4: MRI of the pelvis would be a very accurate test for diagnosing pelvic pathology; however, it is not necessary in this patient who has a history and findings concerning for ovarian torsion. Performing an MRI would only delay treatment.
                                                                                                            • Answer 5: Observation and serial abdominal exams would be the appropriate management of a patient with abdominal pain with a clear etiology after a CT scan had ruled out any serious pathology. This patient’s likely ovarian torsion should not be observed.
                                                                                                            • Summary: Ovarian torsion should be treated with laparoscopy. 

                                                                                                              Review NCCPA Blueprint Topic: Ovarian torsion

                                                                                                              10. A 72-year-old man is brought into the emergency department by emergency medical services. He looks disheveled and states that he is homeless. He has bruising over his arms and legs and states that he does not have a regular source of nutrition. He denies prior medical conditions but states that he still smokes one pack of cigarettes per day. On exam, the patient’s vital signs are normal, but he appears extremely malnourished. His gums are swollen and bleeding and his tongue is unusually smooth. The hair on his arms is pinwheel-shaped. What is the most likely cause?

                                                                                                              1. Iron deficiency
                                                                                                              2. Vitamin B3 deficiency
                                                                                                              3. Vitamin C deficiency
                                                                                                              4. Vitamin B12 deficiency
                                                                                                              5. Vitamin K deficiency
                                                                                                              6. Click here to see the answer

                                                                                                                Answer: C. Vitamin C deficiency

                                                                                                                An elderly, malnourished, cigarette-smoking male with swollen gums, bruising, and corkscrew hair is most likely suffering from vitamin C deficiency.

                                                                                                                Though vitamin C deficiency, or scurvy, is uncommon in the developed world, cases in developing countries still exist. Typically, these cases occur in those who are very old or very young due to the inability to feed themselves properly. Since vitamin C, or ascorbic acid, is found in citrus fruits and green vegetables, deficiency in these foods or consumption of these foods with denatured vitamins (due to over-boiling) can result in deficiency. Those who smoke cigarettes have also been found to be more deficient in vitamin C.

                                                                                                                Incorrect Answers:

                                                                                                                • Answer 1: Iron deficiency anemia would most commonly be asymptomatic, and if serious, would present with symptoms of fatigue and shortness of breath. It would not present with glossitis or corkscrew hair.
                                                                                                                • Answer 2: Vitamin B3, or niacin, can present with glossitis, but would typically also have the “3 D’s”: diarrhea, dermatitis, and dementia.
                                                                                                                • Answer 4: Vitamin B12 deficiency can also present with glossitis, but it would also have physical exam signs such as numbness and parasthesias of the extremities along with ataxia.
                                                                                                                • Answer 5: Vitamin K deficiency can present with bleeding and bruising, but it would not present with the other symptoms typically associated with scurvy.
                                                                                                                • Review NCCPA Blueprint Topic: Hypervitaminosis/hypovitaminosis

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                                                                                                                      36 min
                                                                                                                    5. Podcast Episode 73: Ten PANCE and PANRE Audio Board Review Questions
                                                                                                                      The Audio PANCE and PANRE Physician Assistant Board Review Podcast

                                                                                                                      Welcome to episode 73 of the Audio PANCE and PANRE PA Board Review Podcast.

                                                                                                                      Join me as I cover ten PANCE and PANRE Board review questions from the SMARTYPANCE course content following the NCCPA™ content blueprint (download the FREE cheat sheet).

                                                                                                                      This week we will be covering ten general board review questions based on the NCCPA PANCE and PANRE Content Blueprints. 

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                                                                                                                        Podcast Episode 73: Ten Question PANCE and PANRE Podcast Quiz

                                                                                                                        The following questions are linked to NCCPA Content Blueprint lessons from the Smarty PANCE and PANRE Board Review Website. If you are a member you will be able to log in and view this interactive video lesson.

                                                                                                                        1. A 45-year obese female (BMI=36.7 ) presents to your clinic with a random serum glucose level of 242.  You diagnose the patient with type II diabetes and place her on metformin 500 mg twice daily and ask that she check her glucose first thing in the morning and again late at night. The patient states that her glucose first thing in the morning is 424 and by the evening it is 96.  Which of the following tests would you like to order to confirm your diagnosis?

                                                                                                                        1. ACTH level
                                                                                                                        2. HgA1C
                                                                                                                        3. 24 collection of VMA
                                                                                                                        4. Dexamethasone suppression test
                                                                                                                        5. Cortisol levels
                                                                                                                        6. Click here to see the answer

                                                                                                                          Answer: D. Dexamethasone suppression test

                                                                                                                          This patient is presenting with elevated glucose levels in the morning and normal levels at night. This is due to the dawn phenomenon or secreting too much cortisol first thing in the morning which is very common in patients with Cushing syndrome. The diagnostic test of choice for Cushing syndrome is a dexamethasone suppression test. While it is true that the cortisol levels will be elevated this does not diagnose Cushing’s syndrome.

                                                                                                                          Review NCCPA Blueprint Topic: Cushing’s syndrome

                                                                                                                          2. A 49-year-old male is admitted to the hospital with a diagnosis of pneumonia. He has had a cough and fever up to 101.2 °F for five days.  The patient states that his cough is productive and he is also complaining of sharp right-sided chest pain. On physical exam, you note diminished breath sounds on the right as well as dullness to percussion.  The chest x-ray demonstrates a right lower lobe infiltrate. Which of the following bacteria would be the most likely cause of this patient’s pneumonia?

                                                                                                                          1. Mycoplasma
                                                                                                                          2. Pneumococcal
                                                                                                                          3. H. Flu
                                                                                                                          4. Legionnaires 
                                                                                                                          5. Chlamydia
                                                                                                                          6. Click here to see the answer

                                                                                                                            Answer: B. Pneumococcal

                                                                                                                            Pneumococcal pneumonia is the most common form of pneumonia in an adult that is greater than 40. It usually presents as lobar pneumonia with dullness to percussion and diminished breath sounds. There is also a vaccination available. Mycoplasma is the most common form of pneumonia in young adults and those less than 40.

                                                                                                                            Review NCCPA Blueprint Topic: Bacterial pneumonia (ReelDx)

                                                                                                                            3. A 21-year-old male is brought into the emergency room by his fraternity brothers. He appears confused and is agitated. He has a temperature of 100.5 F, horizontal nystagmus, muscular rigidity and at times becomes incredibly combative. His laboratory evaluation shows a CPK level of 8000 and his blood alcohol level is 0. Which of the following drugs most likely explains this patient’s symptoms?

                                                                                                                            1. Methamphetamines
                                                                                                                            2. LSD
                                                                                                                            3. PCP
                                                                                                                            4. Ecstasy 
                                                                                                                            5. Marijuana
                                                                                                                            6. Click here to see the answer

                                                                                                                              Answer: C. PCP

                                                                                                                              PCP can cause extreme agitation as well as fever, muscular rigidity, horizontal nystagmus, and rhabdomyolysis.  The best treatment for these patients is IV fluids and sedation with medications like Geodon, Haldol, Thorazine, and Ativan. You can also add Benadryl to this cocktail.

                                                                                                                              Review NCCPA Blueprint Topic: Substance-related and addictive disorders

                                                                                                                              4. A 51-year-old male presents to the ED complaining of substernal burning discomfort. He reports a history of mild hypertension and Raynaud’s phenomenon. On physical exam, you notice he has shortened fingers. When further questioned the patients states that he was once told that he may have a type of autoimmune disease but is unaware of the name. Which of the following medications would be most helpful for the patient’s chronic heartburn??

                                                                                                                              1. Omeprazole
                                                                                                                              2. Cimetidine
                                                                                                                              3. Carafate
                                                                                                                              4. Zofran
                                                                                                                              5. Amlodipine
                                                                                                                              6. Click here to see the answer

                                                                                                                                Answer: E. Amlodipine

                                                                                                                                The patient’s symptoms of heartburn, hypertension, Raynaud’s phenomenon, and short fingers are consistent with scleroderma. The best treatment for the reflux esophagitis that can occur with scleroderma is a calcium channel blocker. Calcium channel blockers serve as a smooth muscle relaxant which will relax his tight esophagus resulting in increased mobility and fewer chances for heartburn.

                                                                                                                                Review NCCPA Blueprint Topic: Systemic sclerosis – Scleroderma

                                                                                                                                5. You are called to see a patient who is currently on multiple psychiatric medications including Lithium, Lorazepam, Abilify, Trazodone, and Sertraline. He also takes Lasix.  He is in an assisted living facility and is brought to you by his care team for an acute psychotic episode. Which of the following medications is most likely responsible for the patient’s acute psychosis?

                                                                                                                                1. Lorazepam
                                                                                                                                2. Lasix
                                                                                                                                3. Abilify
                                                                                                                                4. Trazodone
                                                                                                                                5. Sertraline
                                                                                                                                6. Click here to see the answer

                                                                                                                                  Answer: B. Lasix

                                                                                                                                  Loop diuretics can be very problematic in patients taking psychiatric medications. Loop diuretic result in a loss of water in the vascular volume, henceforth levels of different psychiatric medications will become higher. For example, if a patient is on lithium and they are currently on Lasix lithium level becomes higher and they can become with lithium toxic.

                                                                                                                                  Review NCCPA Blueprint Topic: Schizophrenia spectrum and other psychotic disorders

                                                                                                                                  6. A young healthy female patient with a recent diagnosis of depression complains of a 4-month history of amenorrhea and decreased sex drive. She has no significant past medical history and usually has normal menstrual cycles. Which of the following medications is most likely the cause of this patient’s symptoms?

                                                                                                                                  1. Sertraline
                                                                                                                                  2. Trazodone
                                                                                                                                  3. Abilify
                                                                                                                                  4. Venlafaxine
                                                                                                                                  5. Risperidone
                                                                                                                                  6. Click here to see the answer

                                                                                                                                    Answer: E. Risperidone

                                                                                                                                    Older (second-generation) atypical antipsychotic agents can cause elevations in plasma prolactin concentrations while the newer atypical antipsychotics have minimal effect. Risperidone (an older second-generation antipsychotic agent) can cause amenorrhea, sexual dysfunction, and infertility.

                                                                                                                                    Review NCCPA Blueprint Topic: Depressive disorders (Pearls)

                                                                                                                                    7. A 64-year-old male presents with a chief complaint of lower extremity pain while walking his dog every afternoon. What is the most important risk factor for developing peripheral vascular disease?

                                                                                                                                    1. Smoking
                                                                                                                                    2. Hypertension
                                                                                                                                    3. Elevated cholesterol
                                                                                                                                    4. Elevated triglycerides
                                                                                                                                    5. Diabetes
                                                                                                                                    6. Click here to see the answer

                                                                                                                                      Answer: A. Smoking

                                                                                                                                      Smoking is the strongest risk factor for PVD. As a class of drugs view nicotine as a very potent vasoconstrictor causing vasoconstriction everywhere. For example vasoconstriction of the vessels in the heart=CAD which can lead to MI. Constricted blood vessels in the brain=CVA and constricted blood vessels in the periphery=PVD.

                                                                                                                                      Review NCCPA Blueprint Topic: Peripheral artery disease (Lesson)

                                                                                                                                      8. A 35-year-old male patient presents concerned about his cardiac risk factors. He has a low HDL level, hypertension, type II DM, and an elevated LDL and triglyceride levels. His brother had CAD at the age of 47. Which of the following risk factor has the highest value when determining this patients risk of developing CAD?

                                                                                                                                      1. Low HDL levels
                                                                                                                                      2. Hypertension
                                                                                                                                      3. Diabetes
                                                                                                                                      4. High cholesterol
                                                                                                                                      5. Family history
                                                                                                                                      6. Click here to see the answer

                                                                                                                                        Answer: C. Diabetes

                                                                                                                                        Diabetes is the strongest risk factor for CAD. All the other choices are risk factors however they do not have the same predictive value as diabetes when it comes to the severity of CAD.

                                                                                                                                        Review NCCPA Blueprint Topic: Coronary Heart Disease (PEARLS)

                                                                                                                                        9. Which of the following is considered to be a 1st line medication used in endocarditis prophylaxis for high-risk patients undergoing invasive procedures such as an esophageal stricture dilation?

                                                                                                                                        1. Cipro
                                                                                                                                        2. Clindamycin
                                                                                                                                        3. Amoxicillin
                                                                                                                                        4. Clarithromycin
                                                                                                                                        5. Doxycycline
                                                                                                                                        6. Click here to see the answer

                                                                                                                                          Answer: C. Amoxicillin

                                                                                                                                          Amoxicillin is the prophylactic agent of choice against endocarditis, as it is able to cover both gram-negative and gram-positive organisms. If the patient is PCN allergic then Clindamycin is the next best choice.

                                                                                                                                          Review NCCPA Blueprint Topic: Acute and subacute bacterial endocarditis

                                                                                                                                          10. In a patient with a VSD murmur which of the following will be seen during the physical exam?

                                                                                                                                          1. Split S1
                                                                                                                                          2. Diastolic crescendo murmur
                                                                                                                                          3. Wide pulse pressures
                                                                                                                                          4. Holosystolic murmur
                                                                                                                                          5. Split S2
                                                                                                                                          6. Click here to see the answer

                                                                                                                                            Answer: D. Holosystolic murmur

                                                                                                                                            In VSD the patient will have a holosystolic murmur moving from left to right during systole causing more blood to move into the right ventricle and pulmonary artery. End game is pulmonary hypertension.

                                                                                                                                            Review NCCPA Blueprint Topic: Ventricular septal defect

                                                                                                                                            [spoiler title=”C

                                                                                                                                            Looking for all the podcast episodes?

                                                                                                                                            This FREE series is limited to every other episode, you can download and enjoy the complete audio series by joining The PANCE and PANRE Exam Academy + SMARTYPANCE

                                                                                                                                            I will be releasing new episodes every few weeks. The Academy is discounted, so sign up now.

                                                                                                                                            Resources and Links From The Show
                                                                                                                                            • My list of recommended PANCE and PANRE review books
                                                                                                                                            • Interactive PANCE and PANRE NCCPA Exam Content Blueprints
                                                                                                                                            • Sign up for the FREE Daily PANCE and PANRE email series
                                                                                                                                            • Join the Smarty PANCE NCCPA Content Blueprint Website + The PA Life Academy
                                                                                                                                            • Get 20% of any Picmonic membership by using this link
                                                                                                                                            • Use Code "PALIFE" and get 10% OFF THE RUTGERS PANCE AND PANRE REVIEW COURSE
                                                                                                                                            • This Podcast is also available on iTunes and Stitcher Radio for Android
                                                                                                                                              1. iTunes: The Audio PANCE AND PANRE Podcast iTunes
                                                                                                                                              2. Stitcher Radio: The Audio PANCE and PANRE Podcast Stitcher
                                                                                                                                              3. Download The Content Blueprint Checklist

                                                                                                                                                Follow this link to download your FREE copy of the Content Blueprint Checklist

                                                                                                                                                Print it up and start crossing out the topics you understand, marking the ones you don't and making notes of key terms you should remember. The PDF version is interactive and linked directly to the individual lessons on SMARTY PANCE.

                                                                                                                                                Download for PANCE Download for PANRE

                                                                                                                                                16 min
                                                                                                                                              4. Podcast Episode 71: Ten PANCE and PANRE Audio Board Review Questions
                                                                                                                                                The Audio PANCE and PANRE Physician Assistant Board Review Podcast

                                                                                                                                                Welcome to episode 71 of the Audio PANCE and PANRE PA Board Review Podcast.

                                                                                                                                                Join me as I cover ten PANCE and PANRE Board review questions from the SMARTYPANCE course content following the NCCPA™ content blueprint (download the FREE cheat sheet).

                                                                                                                                                This week we will be covering ten general board review questions based on the NCCPA PANCE and PANRE Content Blueprints. 

                                                                                                                                                Below you will find an interactive exam to complement the podcast.

                                                                                                                                                I hope you enjoy this free audio component to the examination portion of this site. The full board review includes over 2,000 interactive board review questions and is available to all members of the PANCE and PANRE Academy and Smarty PANCE.

                                                                                                                                                • You can download and listen to past FREE episodes here, on iTunes, on Google Play Music or Stitcher Radio.
                                                                                                                                                • You can listen to the latest episode, take an interactive quiz and download your results below.
                                                                                                                                                • Listen Carefully Then Take The Practice Exam

                                                                                                                                                  If you can’t see the audio player click here to listen to the full episode.

                                                                                                                                                  Podcast Episode 71: Ten Question PANCE and PANRE Podcast Quiz

                                                                                                                                                  The following questions are linked to NCCPA Content Blueprint lessons from the Smarty PANCE and PANRE Board Review Website. If you are a member you will be able to log in and view this interactive video lesson.

                                                                                                                                                  1. A 52-year-old male presents complaining of urinary frequency, with hesitancy, and nocturia for the past few months. During his physical examination, you note a nontender, non-enlarged prostate with an isolated right posterior lobe nodule. Which of the following options is most appropriate?

                                                                                                                                                  1. order a serum acid phosphatase level
                                                                                                                                                  2. initiate prazosin and schedule a follow-up appointment in 6 weeks
                                                                                                                                                  3. refer the patient for an ultrasound of the prostate and order a PSA level
                                                                                                                                                  4. reassure the patient and schedule a follow-up appointment in six months
                                                                                                                                                  5. initiate norfloxacin therapy for seven days and schedule follow-up in two weeks
                                                                                                                                                  6. Click here to see the answer

                                                                                                                                                    Answer: C. refer the patient for an ultrasound of the prostate and order a PSA level

                                                                                                                                                    This patient has an isolated nodule of the prostate gland — cancer until proven otherwise. You should order an ultrasound and a PSA. BPH will present as diffuse enlargement and not a discrete nodule.

                                                                                                                                                    Review NCCPA Blueprint Topic: Prostate disorders (PEARLS)

                                                                                                                                                    2. Which of the following is a major contraindication to curative surgical resection of a lung tumor?

                                                                                                                                                    A. Liver metastases
                                                                                                                                                    B. Vagus nerve involvement
                                                                                                                                                    C. Non-malignant pleural effusion
                                                                                                                                                    D. Chest wall invasion of the tumor

                                                                                                                                                    Click here to see the answer

                                                                                                                                                    Answer: A. Liver metastases

                                                                                                                                                    Distant metastases, except for solitary brain and adrenal metastases are an absolute contraindication for pulmonary resection. Other absolute contraindications include MI within the past 3 months, superior vena cava syndrome due to a metastatic tumor, bilateral endobronchial tumor, contralateral lymph node metastases, and malignant pleural effusion.

                                                                                                                                                    Review NCCPA Blueprint Topic: Pulmonary Neoplasms (PEARLS)

                                                                                                                                                    3. A 23-year-old female complains of fever and genital pain. Examination reveals the presence of lymphadenopathy in the groin and the presence of vulvar vesicles surrounded by erythematous skin. The diagnosis may be confirmed by

                                                                                                                                                    A. A culture of a vesicle using blood agar medium
                                                                                                                                                    B. The presence of similar lesions on the fingers and hands
                                                                                                                                                    C. A Gram stain of a scraping from the base of the lesion
                                                                                                                                                    D. The presence of giant multinucleated cells on Tzanck smear

                                                                                                                                                    Click here to see the answer

                                                                                                                                                    Answer: D. The presence of giant multinucleated cells on Tzanck smear – A Tzanck smear is the standard laboratory test to confirm the herpes virus as an etiologic agent of a vesicular lesion on an erythematous base.

                                                                                                                                                    A. Herpes virus will not grow on blood agar medium.

                                                                                                                                                    B. Herpes genitalis occurs in skin that comes into contact with the herpes virus. Usually, the infection is localized.
                                                                                                                                                    C. A Gram stain will not identify the herpes virus.

                                                                                                                                                    Review NCCPA Blueprint Topic: Herpes simplex (ReelDx)

                                                                                                                                                    4. A 28-year-old woman is complaining of heavy uterine bleeding and pelvic pressure that has progressively worsened over the past year. Evaluation reveals multiple moderate-sized uterine fibroids. The patient desires to have more children. The most appropriate definitive treatment is

                                                                                                                                                    A. Myomectomy
                                                                                                                                                    B. Hysterectomy
                                                                                                                                                    C. GnRH agonists
                                                                                                                                                    D. Oral progesterone

                                                                                                                                                    Click here to see the answer

                                                                                                                                                    Answer: A. Myomectomy –  Myomectomy is the definitive treatment of choice for moderate-sized uterine fibroids in young women who desire to maintain reproductive capability.

                                                                                                                                                    B. Hysterectomy is indicated as definitive treatment in a patient who does not desire to maintain reproductive capability.

                                                                                                                                                    C. GnRH agonists are used as an adjunct to surgery for treatment of uterine fibroids. Used alone, they would not be considered a definitive treatment.
                                                                                                                                                    D. Oral progesterone may be used to suppress menorrhagia preoperatively. Used alone, it would not be considered a definitive treatment.;

                                                                                                                                                    Review NCCPA Blueprint Topic:

                                                                                                                                                    5. A 59-year-old otherwise healthy female develops acute dyspnea and chest pain one week post total abdominal hysterectomy. Echocardiogram demonstrates normal heart size with normal right and left ventricular function. Lung scan demonstrates two segmental perfusion defects. Which of the following is the next step in the management of this patient?

                                                                                                                                                    A. Anticoagulation
                                                                                                                                                    B. Embolectomy
                                                                                                                                                    C. Thrombolysis
                                                                                                                                                    D. Inferior vena cava filter

                                                                                                                                                    Click here to see the answer

                                                                                                                                                    Answer: A. Anticoagulation – Anticoagulation is the treatment of choice in patients with pulmonary embolism with normal ventricular function and no absolute contraindications.

                                                                                                                                                    B. Embolectomy is not indicated as the initial treatment of a pulmonary embolism in patients with normal ventricular function.

                                                                                                                                                    C. Thrombolysis is contraindicated in patients within 10 days of having major surgery.
                                                                                                                                                    D. An inferior vena cava filter is considered in patients with contraindications to anticoagulation therapy or failed anticoagulation therapy.

                                                                                                                                                    Review NCCPA Blueprint Topic: Pulmonary embolism (ReelDx)

                                                                                                                                                    6. Long term use of which of the following drugs may cause a drug-induced lupus-type eruption?

                                                                                                                                                    A. prednisone
                                                                                                                                                    B. tetracycline
                                                                                                                                                    C. procainamide
                                                                                                                                                    D. oral contraceptives

                                                                                                                                                    Click here to see the answer

                                                                                                                                                    Answer: C. Procainamide – Procainamide, and hydralazine are the most common drugs that may cause a lupus-like eruption.

                                                                                                                                                    A. Prednisone is not implicated in drug-induced skin reactions.

                                                                                                                                                    B. Tetracycline and sulfonamides are known to cause a photosensitive rash on sun-exposed areas of the skin.
                                                                                                                                                    D. Oral contraceptives may induce erythema nodosum.

                                                                                                                                                    Review NCCPA Blueprint topic: Drug eruptions (ReelDx)

                                                                                                                                                    7. Which of the following clinical manifestations is most commonly seen in viral croup?

                                                                                                                                                    A. drooling
                                                                                                                                                    B. wheezing
                                                                                                                                                    C. sputum production
                                                                                                                                                    D. inspiratory stridor

                                                                                                                                                    Click here to see the answer

                                                                                                                                                    Answer: D. inspiratory stridor – Viral croup typically presents with a barking cough and stridor.

                                                                                                                                                    A. Drooling is common in epiglottitis, not viral croup.

                                                                                                                                                    B. Wheezing is noted in asthma.
                                                                                                                                                    C. Sputum production is noted in bacterial infections.

                                                                                                                                                    Review NCCPA Blueprint Topic: Croup (ReelDx)

                                                                                                                                                    8. Whispered voice test on a patient reveals decreased hearing in the left ear. Which of the following would be most consistent with conductive hearing loss in the left ear?

                                                                                                                                                    A. Sounds best heard in the left ear on Weber test.
                                                                                                                                                    B. Air conduction longer than bone conduction in the left ear on Rinne test.
                                                                                                                                                    C. Sound best heard in the right ear on Weber test.
                                                                                                                                                    D. Bone conduction longer than air conduction in the right ear.

                                                                                                                                                    Click here to see the answer

                                                                                                                                                    Answer: A. Sounds best heard in the left ear on Weber test – Sound best heard in the ear with a decreased hearing on Weber test (in this case, the left ear) is indicative of conductive hearing loss.

                                                                                                                                                    B. With conductive hearing loss, bone conduction should be heard as long as or longer than air conduction of sound in the affected ear. Air conduction lasting longer than bone conduction of sound would indicate a sensorineural hearing loss.

                                                                                                                                                    C. Sound best heard in the ear with an unaffected hearing on Weber test (in this case, the right ear) is indicative of sensorineural hearing loss.
                                                                                                                                                    D. With conductive hearing loss, bone conduction should be heard as long as or longer than air conduction of sound in the affected ear. The right ear showed normal hearing on physical exam.

                                                                                                                                                    Review NCCPA Blueprint Topic: Hearing impairment (Lecture)

                                                                                                                                                    9. A 65-year-old male presents with multiple lesions on his back. He denies any pruritis. Physical examination reveals the presence of multiple scattered brown plaques with a raised, warty surface that appears to be stuck onto the skin and feel greasy. Which of the following is the most likely diagnosis?

                                                                                                                                                    A. lentigines
                                                                                                                                                    B. actinic keratosis
                                                                                                                                                    C. keratoacanthomas
                                                                                                                                                    D. seborrheic keratosis

                                                                                                                                                    Click here to see the answer

                                                                                                                                                    Answer: D. seborrheic keratosis – Seborrheic keratosis is a common benign plaque in the elderly that characteristically has a velvety or warty surface associated with a stuck on appearance and greasy feel.

                                                                                                                                                    A. Lentigines most commonly are seen on the dorsum of the hand and appear as flat brown spots, often with sharp borders.

                                                                                                                                                    B. Actinic keratosis usually presents as small patches of flesh-colored, pink or yellow-brown lesions often with an erythematous component. The lesions are better felt than seen, having a rough, sandpaper feel and are often tender to palpation.
                                                                                                                                                    C. Keratoacanthomas usually occur as an isolated lesion on the face appearing as an erythematous, dome-shaped nodule with a central keratinaceous plug.

                                                                                                                                                    Review NCCPA Blueprint Topic: Keratotic disorders (PEARLS)

                                                                                                                                                    10. You are called to the nursery to see a male infant, born by uncomplicated vaginal delivery. He weighs 2,600 grams and has one deep crease on the anterior third of each foot. Respirations are 88 breaths/minute with expiratory grunting and intercostals retractions. He is cyanotic on room air and becomes pink when placed on 60% oxygen. Chest x-ray shows atelectasis with air bronchograms. Which of the following is the most likely diagnosis?

                                                                                                                                                    A. neonatal pneumonia
                                                                                                                                                    B. congenital heart disease
                                                                                                                                                    C. hyaline membrane disease
                                                                                                                                                    D. chronic lung disease of prematurity

                                                                                                                                                    Click here to see the answer

                                                                                                                                                    Answer: C. hyaline membrane disease – Hyaline membrane disease is the most common cause of respiratory distress in the premature infant. The infant typically presents with tachypnea, cyanosis, and expiratory grunting. A chest x-ray reveals hypoexpansion and air bronchograms.

                                                                                                                                                    A. While tachypnea, grunting, retractions, and cyanosis may be signs of neonatal pneumonia, they are primarily late findings of progressive respiratory distress and would not be seen immediately at the time of delivery. A chest x-ray in pneumonia would also most commonly reveal an infiltrate or effusion.

                                                                                                                                                    B. While congenital heart disease may present with cyanosis, the chest x-ray will reveal a cardiac abnormality, such as cardiomegaly.
                                                                                                                                                    D. Chronic lung disease of prematurity is a complication in about 20% of infants with hyaline membrane disease. It is defined as respiratory symptoms, oxygen requirement and chest x-ray abnormalities at 1 month of age so it cannot be diagnosed at this time in this newborn.;

                                                                                                                                                    Review NCCPA Blueprint Topic:

                                                                                                                                                    Looking for all the podcast episodes?

                                                                                                                                                    This FREE series is limited to every other episode, you can download and enjoy the complete audio series by joining The PANCE and PANRE Exam Academy + SMARTYPANCE

                                                                                                                                                    I will be releasing new episodes every few weeks. The Academy is discounted, so sign up now.

                                                                                                                                                    Resources and Links From The Show
                                                                                                                                                    • My list of recommended PANCE and PANRE review books
                                                                                                                                                    • Interactive PANCE and PANRE NCCPA Exam Content Blueprints
                                                                                                                                                    • Sign up for the FREE daily PANCE and PANRE email series
                                                                                                                                                    • Join the Smarty PANCE NCCPA Content Blueprint Website + The PA Life Academy
                                                                                                                                                    • Get 20% of any Picmonic membership by using this link
                                                                                                                                                    • Use Code “PALIFE” and get 10% OFF THE RUTGERS PANCE AND PANRE REVIEW COURSE
                                                                                                                                                    • This Podcast is also available on iTunes and Stitcher Radio for Android
                                                                                                                                                      1. iTunes: The Audio PANCE AND PANRE Podcast iTunes
                                                                                                                                                      2. Stitcher Radio: The Audio PANCE and PANRE Podcast Stitcher
                                                                                                                                                      3. Download The Content Blueprint Checklist

                                                                                                                                                        Follow this link to download your FREE copy of the Content Blueprint Checklist

                                                                                                                                                        Print it up and start crossing out the topics you understand, marking the ones you don’t and making notes of key terms you should remember. The PDF version is interactive and linked directly to the individual lessons on SMARTY PANCE.

                                                                                                                                                        Download for PANCE Download for PANRE

                                                                                                                                                        23 min
                                                                                                                                                      4. Podcast Episode 69: Ten PANCE and PANRE Board Review Audio Questions
                                                                                                                                                        The Audio PANCE/PANRE Board Review Exam Questions

                                                                                                                                                        Welcome to episode 69 of the Audio PANCE and PANRE PA Board Review Podcast.

                                                                                                                                                        Join me as I cover ten PANCE and PANRE Board review questions from the SMARTYPANCE course content following the NCCPA™ content blueprint (download the FREE cheat sheet).

                                                                                                                                                        This week we will be covering ten general board review questions based on the NCCPA PANCE and PANRE Content Blueprints. 

                                                                                                                                                        Below you will find an interactive exam to complement the podcast.

                                                                                                                                                        I hope you enjoy this free audio component to the examination portion of this site. The full board review includes over 2,000 interactive board review questions and is available to all members of the PANCE and PANRE Academy and Smarty PANCE.

                                                                                                                                                        • You can download and listen to past FREE episodes here, on iTunes, on Google Play Music or Stitcher Radio.
                                                                                                                                                        • You can listen to the latest episode, take an interactive quiz and download your results below.
                                                                                                                                                        • Listen Carefully Then Take The Practice Exam

                                                                                                                                                          If you can’t see the audio player click here to listen to the full episode.

                                                                                                                                                          Podcast Episode 69: 10 Question PANCE and PANRE Podcast Quiz

                                                                                                                                                          The following questions are linked to NCCPA Content Blueprint lessons from the Smarty PANCE and PANRE Board Review Website. If you are a member you will be able to log in and view this interactive video lesson.

                                                                                                                                                          1. Which of the following is the most common cause of acute myocardial infarction?

                                                                                                                                                          A. Occlusion caused by coronary microemboli
                                                                                                                                                          B. Thrombus development at a site of vascular injury
                                                                                                                                                          C. Congenital abnormalities
                                                                                                                                                          D. Severe coronary artery spasm

                                                                                                                                                          Click here to see the answer

                                                                                                                                                          B. Thrombus development at a site of vascular injury – Acute myocardial infarction occurs when a coronary artery thrombus develops rapidly at a site of vascular injury. In most cases, infarction occurs when an atherosclerotic plaque fissures, ruptures, or ulcerates and when conditions favor thrombogenesis so that a mural thrombus forms at the site of rupture and leads to coronary artery occlusion.

                                                                                                                                                          A. Coronary microemboli occlusion is a rare cause of acute myocardial infarction.

                                                                                                                                                          C. Congenital abnormalities are rare causes of acute MI.
                                                                                                                                                          D. Severe coronary artery spasm is more likely to result in Prinzmetal’s angina rather than true infarction.

                                                                                                                                                          Review NCCPA Blueprint Topic: Acute myocardial infarction (PEARLS) (Lesson)

                                                                                                                                                          2. Endotracheal intubation should be performed with caution in patients with which of the following underlying conditions due to the propensity to cause subluxation of C1 on C2?

                                                                                                                                                          A. Rheumatoid arthritis
                                                                                                                                                          B. Osteoarthritis
                                                                                                                                                          C. Gout
                                                                                                                                                          D. Pseudogout

                                                                                                                                                          Click here to see the answer

                                                                                                                                                          A. Rheumatoid arthritis – Patients with advanced rheumatoid arthritis will have synovitis of the atlantoaxial joint (C1-C2) which may damage the transverse ligament of the atlas, producing a forward displacement of the atlas on the axis (atlantoaxial subluxation).

                                                                                                                                                          B. Although patients with osteoarthritis may have neck pain and stiffness, there is no predilection for the atlantoaxial joints.

                                                                                                                                                          C. Patients with gout are likely to have involvement of peripheral joints rather than spinal joints.
                                                                                                                                                          D. Patients with pseudogout are more likely to have involvement of the knees, wrist, shoulder, ankle, elbow, and hands rather than the cervical spine.

                                                                                                                                                          Review NCCPA Blueprint Topic: Rheumatoid arthritis (Lecture) (Lesson)

                                                                                                                                                          3. Which of the following interventions is the treatment of choice for an actinic keratosis?

                                                                                                                                                          A. Mohs surgery
                                                                                                                                                          B. Cryotherapy
                                                                                                                                                          C. Acid peels
                                                                                                                                                          D. Radiation therapy

                                                                                                                                                          Click here to see the answer

                                                                                                                                                          B. Cryotherapy – Cryotherapy is the treatment of choice for isolated superficial actinic keratosis.

                                                                                                                                                          A. Mohs surgery and radiation therapy are not indicated in the treatment for actinic keratosis.

                                                                                                                                                          C. Acid peels can be used to treat actinic keratosis but are not the treatment of choice.

                                                                                                                                                          Review NCCPA Blueprint Topic: Actinic keratosis

                                                                                                                                                          4. A 55-year-old secretary presents with ongoing pain and numbness in her hand. These symptoms are worse at night and she must shake her hand to regain feeling in it. Which of the following physical examination signs will be
                                                                                                                                                          present?

                                                                                                                                                          A. Hypothenar atrophy
                                                                                                                                                          B. Weakness of finger abduction
                                                                                                                                                          C. Inability to maintain wrist extension against resistance
                                                                                                                                                          D. Weakness of thumb abduction

                                                                                                                                                          Click here to see the answer

                                                                                                                                                          D. A weakness of thumb abduction – Median nerve injury causes weakness of thumb abduction (measured by thumb opposition strength) along with thenar atrophy. Tinel’s and Phalen’s signs will also be positive with carpal tunnel syndrome.

                                                                                                                                                          A. Hypothenar atrophy may occur with aging and disuse but it is not part of the median nerve involvement that occurs with carpal tunnel syndrome.

                                                                                                                                                          B. Finger abduction weakness is associated with ulnar nerve injury, which does not occur with carpal tunnel syndrome.
                                                                                                                                                          C. Radial nerve injury causes weakness of wrist extension and this is not part of carpal tunnel syndrome.

                                                                                                                                                          Review NCCPA Blueprint Topic: Carpal Tunnel Syndrome (Lesson)

                                                                                                                                                          5. A 78-year-old male with history of coronary artery disease status post-CABG and ischemic cardiomyopathy presents with a complaint of progressive dyspnea and orthopnea. He also complains of lower extremity edema. The patient denies fever, chest pain, or cough. On physical examination, vital signs are BP 120/68, HR 75 and regular, RR 22, afebrile. You note the patient to have an S3 heart sound, jugular venous distention, and 2+ lower extremity edema. The patient is admitted and treated. Upon discharge from the hospital, the patient should be educated to monitor which of the following at home?

                                                                                                                                                          A. Daily weights
                                                                                                                                                          B. Daily spirometry
                                                                                                                                                          C. Daily blood glucose
                                                                                                                                                          D. Daily fat intake

                                                                                                                                                          Click here to see the answer

                                                                                                                                                          A. Daily weights – Home monitoring of daily weights can alert the health care provider to the early recognition of worsening heart failure.

                                                                                                                                                          B. Spirometry monitoring is important in a patient with asthma, not heart failure.

                                                                                                                                                          C. Daily blood glucose monitoring is important in a patient with diabetes, not heart failure.
                                                                                                                                                          D. Daily fat intake is important, but will not improve his heart failure management.

                                                                                                                                                          Review NCCPA Blueprint Topic: Heart Failure (ReelDx) (Lesson)

                                                                                                                                                          6. Which of the following rotator cuff tendons is most likely to sustain injury because of its repeated impingement (carpal tunnel syndrome) between the humeral head and the undersurface of the anterior third of the acromion and coracoacromial ligament?

                                                                                                                                                          A. Supraspinatus
                                                                                                                                                          B. Infraspinatus
                                                                                                                                                          C. Teres minor
                                                                                                                                                          D. Subscapularis

                                                                                                                                                          Click here to see the answer

                                                                                                                                                          A. Supraspinatus – A critical zone exists for the supraspinatus tendon due to its superior insertion site. It is susceptible for injury because it has a reduction in its blood supply that occurs with abduction of the arm. Impingement of the shoulder is most commonly seen with the supraspinatus tendon, the long head of the biceps tendon and/or the subacromial bursa.

                                                                                                                                                          Review NCCPA Blueprint topic: Soft tissue injuries of the forearm, wrist, and hand (ReelDx) (Lesson)

                                                                                                                                                          7. Which of the following diagnostic findings in the urinary sediment is specific for a diagnosis of chronic renal failure?

                                                                                                                                                          A. Hematuria
                                                                                                                                                          B. Proteinuria
                                                                                                                                                          C. Broad waxy casts
                                                                                                                                                          D. Hyaline casts

                                                                                                                                                          Click here to see the answer

                                                                                                                                                          C. Broad waxy casts – Broad waxy casts in urinary sediment are a specific finding in chronic renal failure.

                                                                                                                                                          A. Hematuria and proteinuria are frequent, but nonspecific, findings in chronic renal failure.

                                                                                                                                                          D. Hyaline casts may be found in normal urine or in states of dehydration.

                                                                                                                                                          Review NCCPA Blueprint Topic: Chronic kidney disease (Lesson)

                                                                                                                                                          8. In addition to tobacco products, which of the following is also considered a major risk factor in the development of oral cancer?

                                                                                                                                                          A. Sun exposure
                                                                                                                                                          B. Alcohol abuse
                                                                                                                                                          C. Occupational exposure
                                                                                                                                                          D. History of oral candidiasis

                                                                                                                                                          Click here to see the answer

                                                                                                                                                          B. Alcohol abuse – Major risk factors for the development of oral cancer are the use of tobacco products and alcohol abuse.

                                                                                                                                                          A. Sun exposure is a risk factor for cancer of the lip but is not considered a major risk factor for oral cancer.

                                                                                                                                                          C. While occupational exposures and the presence of premalignant lesions, such as leukoplakia, are risk factors for the development of oral cancer, they are not considered major risk factors.
                                                                                                                                                          D. History of oral candidiasis has no correlation to the development of oral cancer.

                                                                                                                                                          Review NCCPA Blueprint Topic: EENT Benign and Malignant Neoplasms (Lesson)

                                                                                                                                                          9. A 13-year-old boy with leukemia presents with epistaxis for 2 hours. The bleeding site appears to be from Kiesselbach’s area. The most appropriate intervention is

                                                                                                                                                          A. electrocautery of the bleeding site
                                                                                                                                                          B. silver nitrate application
                                                                                                                                                          C. posterior nasal packing
                                                                                                                                                          D. intranasal petrolatum gauze

                                                                                                                                                          Click here to see the answer

                                                                                                                                                          D. intranasal petrolatum gauze – Petrolatum gauze will provide pressure to the bleeding point while the cause of bleeding is corrected.

                                                                                                                                                          A. Cautery is not used because the edges of the cauterized area may begin to bleed.

                                                                                                                                                          B. Silver nitrate is not used in children because it increases the risk of nasal septal perforation.
                                                                                                                                                          C. Posterior nasal packing is indicated for posterior bleeds in the inferior meatus.

                                                                                                                                                          Review NCCPA Blueprint Topic: Epistaxis (ReelDx + Lecture) (Lesson)

                                                                                                                                                          10. A 2-year-old female presents with purulent nasal discharge bilaterally with fever and cough for several days. Her mom had taken her out of daycare for a similar occurrence 2 months ago, that was treated with Amoxicillin. Exam further reveals halitosis and periorbital edema. Treatment should be initiated with which of the following?

                                                                                                                                                          A. Antihistamines
                                                                                                                                                          B. Ribavirin (Rebetol)
                                                                                                                                                          C. Intranasal corticosteroids
                                                                                                                                                          D. Amoxicillin-clavulanate (Augmentin)

                                                                                                                                                          Click here to see the answer

                                                                                                                                                          D. Amoxicillin-clavulanate (Augmentin) – High dose amoxicillin-clavulanate is the treatment of choice for resistant bacterial sinusitis, especially in children presenting with risk factors (daycare attendance, previous antibiotic treatment 1-3 months prior, age younger than 2 years).

                                                                                                                                                          A. Antihistamines and intranasal corticosteroids have not been adequately studied in children to prove they make a difference in treating recurrent sinusitis.

                                                                                                                                                          B. Ribavirin is approved for the treatment of RSV infection.

                                                                                                                                                          Review NCCPA Blueprint Topic: Acute and chronic sinusitis (ReelDx + Lecture) (Lesson)

                                                                                                                                                          Looking for all the podcast episodes?

                                                                                                                                                          This FREE series is limited to every other episode, you can download and enjoy the complete audio series by joining The PANCE and PANRE Exam Academy + SMARTYPANCE

                                                                                                                                                          I will be releasing new episodes every few weeks. The Academy is discounted, so sign up now.

                                                                                                                                                          Resources and Links From The Show
                                                                                                                                                          • My list of recommended PANCE and PANRE review books
                                                                                                                                                          • Download the FREE PANCE and PANRE Blueprint Checklist
                                                                                                                                                          • Sign up for the FREE daily PANCE and PANRE email series
                                                                                                                                                          • Join the Smarty PANCE NCCPA Content Blueprint Website + The PA Life Academy
                                                                                                                                                          • Get 20% of any Picmonic membership by using this link
                                                                                                                                                          • Use Code “PALIFE” and get 10% OFF THE RUTGERS PANCE AND PANRE REVIEW COURSE
                                                                                                                                                          • This Podcast is also available on iTunes and Stitcher Radio for Android
                                                                                                                                                            1. iTunes: The Audio PANCE AND PANRE Podcast iTunes
                                                                                                                                                            2. Stitcher Radio: The Audio PANCE and PANRE Podcast Stitcher
                                                                                                                                                            3. Download The Content Blueprint Checklist

                                                                                                                                                              Follow this link to download your FREE copy of the Content Blueprint Checklist

                                                                                                                                                              Print it up and start crossing out the topics you understand, marking the ones you don’t and making notes of key terms you should remember. The PDF version is interactive and linked directly to the individual lessons on SMARTY PANCE.

                                                                                                                                                              Download for PANCE Download for PANRE

                                                                                                                                                              19 min
                                                                                                                                                            4. Podcast Episode 67: Ten PANCE and PANRE Board Review Audio Questions
                                                                                                                                                              Ten Mixed PA Board Review Questions
                                                                                                                                                              The Audio PANCE/PANRE – Ten PA Board Review Exam Questions

                                                                                                                                                              Welcome to episode 67 of the Audio PANCE and PANRE PA Board Review Podcast.

                                                                                                                                                              Join me as I cover ten PANCE and PANRE Board review questions from the SMARTYPANCE course content following the NCCPA™ content blueprint (download the FREE cheat sheet).

                                                                                                                                                              This week we will be covering ten general board review questions based on the NCCPA PANCE and PANRE Content Blueprint. 

                                                                                                                                                              Below you will find an interactive exam to complement the podcast.

                                                                                                                                                              I hope you enjoy this free audio component to the examination portion of this site. The full board review includes over 2,000 interactive board review questions and is available to all members of the PANCE and PANRE Academy and SMARTYPANCE which are now bundled together into one very low price.

                                                                                                                                                              • You can download and listen to past FREE episodes here, on iTunes, on Google Play Music or Stitcher Radio.
                                                                                                                                                              • You can listen to the latest episode, take an interactive quiz and download your results below.
                                                                                                                                                              • Listen Carefully Then Take The Practice Exam

                                                                                                                                                                If you can’t see the audio player click here to listen to the full episode.

                                                                                                                                                                Podcast Episode 67: 10 Question PANCE and PANRE Podcast Quiz

                                                                                                                                                                The following questions are linked to NCCPA Content Blueprint lessons from the SMARTYPANCE & PANRE Board Review Website. If you are a member you will be able to log in and view this interactive video lesson.

                                                                                                                                                                A 26-year-old female presents with several pruritic lesions on her dorsal forearms. The lesions are erythematous with vesicles, with a few beginning to weep. She works in a photography laboratory but denies any other possible exposures. Which of the following is the most useful diagnostic test?

                                                                                                                                                                A. VDRL serology
                                                                                                                                                                B. KOH prep
                                                                                                                                                                C. Patch testing
                                                                                                                                                                D. Gram’s stain

                                                                                                                                                                Click here to see the answer

                                                                                                                                                                C. Patch testing with a suspected agent is usually positive in cases of allergic contact dermatitis

                                                                                                                                                                A. VDRL serology is useful in the diagnosis of syphilis, not contact dermatitis

                                                                                                                                                                B. KOH prep is used for diagnosis of fungal infections, not contact dermatitis
                                                                                                                                                                D. Gram’s stain is useful in the diagnosis of bacterial infections, not contact dermatitis

                                                                                                                                                                2. An elderly female presents for evaluation of exertional syncope, dyspnea, and angina. She admits that previous to these symptoms she had insidious progression of fatigue that caused her to curtail her activities. Which of the following is the most likely diagnosis?

                                                                                                                                                                A. Aortic stenosis
                                                                                                                                                                B. Aortic regurgitation
                                                                                                                                                                C. Mitral stenosis
                                                                                                                                                                D. Mitral valve prolapse

                                                                                                                                                                Click here to see the answer

                                                                                                                                                                A. The major symptoms of aortic stenosis are exertional syncope, dyspnea, and angina. Symptoms do not become apparent for a number of years and usually are not present until the valve is narrowed to less than 0.5 cm to 2 cm of the valve surface area.

                                                                                                                                                                B. Patients with aortic regurgitation are likely to complain of an uncomfortable awareness of their heart, especially when lying down. These patients develop sinus tachycardia with exertion and complain of palpitations and head pounding with activity.

                                                                                                                                                                C. The symptoms related to mitral stenosis are related to increased pulmonary pressure after the left atrium can no longer overcome the outflow obstruction.
                                                                                                                                                                D. Patients with mitral valve prolapse are typically asymptomatic throughout their lives, although a wide range of
                                                                                                                                                                symptoms is possible. When symptoms do occur, palpitations from arrhythmias are most common along with lightheadedness. Syncope is not part of this disease process.

                                                                                                                                                                3. A 40-year-old female G5P5 complains of small quantities of urine leaking when she coughs, sneezes, or laughs. Her genitourinary examination is unremarkable and her urinalysis is normal. At this time, which of the following is the most appropriate management plan?

                                                                                                                                                                A. Refer for a cystoscopy
                                                                                                                                                                B. Recommend Kegel exercises
                                                                                                                                                                C. Refer for surgical correction
                                                                                                                                                                D. Recommend hormone replacement therapy

                                                                                                                                                                Click here to see the answer

                                                                                                                                                                B. Strengthening the pelvic muscles by Kegel exercises and emptying the bladder frequently may resolve the problem.

                                                                                                                                                                A. Conservative therapy for stress incontinence should be attempted prior to any evaluation, such as cystoscopy, that might indicate the need for surgical correction

                                                                                                                                                                D. There is no indication in the history for hormone replacement therapy and no vaginal atrophy was noted on pelvic examination

                                                                                                                                                                4. A 62-year-old male presents with complaints of vague epigastric abdominal pain associated with jaundice and generalized pruritus. Physical examination reveals jaundice and a palpable non-tender gallbladder but is otherwise unremarkable. Which of the following is the most likely diagnosis?

                                                                                                                                                                A. Viral hepatitis
                                                                                                                                                                B. Pancreatic cancer
                                                                                                                                                                C. Acute cholecystitis
                                                                                                                                                                D. Gilbert’s syndrome

                                                                                                                                                                Click here to see the answer

                                                                                                                                                                B. Pancreatic cancer is suggested by the vague epigastric pain with jaundice resulting from biliary obstruction due to cancer involving the pancreatic head. The presence of a palpable non-tender gallbladder (Courvoisier’s sign) also indicates obstruction due to the cancer

                                                                                                                                                                A. While viral hepatitis may cause jaundice, the liver is enlarged and tender

                                                                                                                                                                C. While acute cholecystitis may present with jaundice and an enlarged gallbladder, the pain is classically colicky and located in the right upper quadrant. On physical examination with deep inspiration and palpation of the right subcostal area increased pain and respiratory arrest (Murphy’s sign) is usually seen.
                                                                                                                                                                D. Gilbert’s syndrome is the most common of the hereditary hyperbilirubinemias. It is most often diagnosed near puberty or adult life based on results of a comprehensive metabolic panel.

                                                                                                                                                                5. Which of the following would you expect on physical examination in a patient with mitral valve stenosis?

                                                                                                                                                                A. Systolic blowing murmur
                                                                                                                                                                B. Opening snap
                                                                                                                                                                C. Mid-systolic click
                                                                                                                                                                D. Paradoxically split S2

                                                                                                                                                                Click here to see the answer

                                                                                                                                                                B. Mitral stenosis is characterized by a mid-diastolic opening snap

                                                                                                                                                                A. Mitral stenosis is a diastolic, not a systolic murmur

                                                                                                                                                                C. Mid-systolic clicks are noted in mitral valve prolapse, not mitral stenosis
                                                                                                                                                                D. Paradoxical splitting of S2 occurs in aortic stenosis, not mitral stenosis

                                                                                                                                                                Review PANCE and PANRE Valvular disorders pearls

                                                                                                                                                                6. A positive Wood’s light examination (fluorescence) demonstrates

                                                                                                                                                                A. viral infection with herpes zoster
                                                                                                                                                                B. bacterial infection with Treponema pallidum
                                                                                                                                                                C. parasitic infestation with Pediculus humanus
                                                                                                                                                                D. mycotic infection with Microsporum canis

                                                                                                                                                                Click here to see the answer

                                                                                                                                                                D. Microsporum causes tinea capitis and fluoresces blue-green under Wood’s light

                                                                                                                                                                A. Lesions of herpes, Treponema, and Pediculus infections do not fluoresce.

                                                                                                                                                                Review topic PANCE Dermatologic system dermatophyte infections

                                                                                                                                                                7. In which of the following patients would one most likely find acanthosis nigricans?

                                                                                                                                                                A. A 55-year-old obese female with hyperinsulinemia
                                                                                                                                                                B. A 55-year-old male with an enlarged spleen and pancytopenia
                                                                                                                                                                C. A 24-year-old female with increased Lyme titers
                                                                                                                                                                D. A 60-year-old male with increased triglycerides

                                                                                                                                                                Click here to see the answer

                                                                                                                                                                A. Acanthosis nigricans is associated with patients who have hyperinsulinemia

                                                                                                                                                                B. Hairy cell leukemia is associated with an enlarged spleen and pancytopenia. Acanthosis nigricans is not a cutaneous manifestation

                                                                                                                                                                C. Erythema chronicum migrans is the characteristic lesion associated with Lyme disease
                                                                                                                                                                D. Eruptive xanthelasma is associated with increased triglycerides

                                                                                                                                                                8. A 65-year-old male presents with back pain two days after he was shoveling snow. The patient complains of pain in his low back that radiates into his buttocks, posterior thigh and calf, and the bottom of his foot. There is associated numbness of the lateral and plantar surface of his foot. Which of the following disc herniations is most likely to be affected?

                                                                                                                                                                A. L3-L4
                                                                                                                                                                B. L4-L5
                                                                                                                                                                C. L5-S1
                                                                                                                                                                D. S1-S2

                                                                                                                                                                Click here to see the answer

                                                                                                                                                                C. The S1 nerve root impingement is most likely to occur from the herniation of the L5-S1 disc space. The S1 disc affects Achilles’ reflex, the gastrocnemius and soleus muscles, and the abductor hallucis and gluteus maximus muscles.

                                                                                                                                                                9. A 22-year-old female presents to the emergency department with a rapid heart rate. She appears quite thin and dehydrated. She denies that she is thin, stating “I am so fat that I can hardly stand myself! That is why I exercise every day.” She runs twelve to fifteen miles a day, and on weekends also bicycles forty to fifty miles. Her LMP was six months ago. On exam, she is 5′ 6″ tall and weighs 98 pounds. Temp 98 degrees F, pulse 100, respirations 18, BP 98/60. EKG shows sinus tachycardia. Laboratory findings include Na 138 mEq/L, K 2.8 mEq/L, Cl 91 mEq/L, BUN 35 mg/dL, Creatinine 1.1 mg/dL. Which of the following is the next most appropriate treatment?

                                                                                                                                                                A. Propylthiouracil (PTU) and individual psychotherapy
                                                                                                                                                                B. Hormone replacement and cognitive therapy
                                                                                                                                                                C. Weight restoration and family therapy
                                                                                                                                                                D. IV hydration and antidepressant therapy

                                                                                                                                                                Click here to see the answer

                                                                                                                                                                C. Anorexia nervosa requires a comprehensive, multidisciplinary approach to treatment that integrates medical management, individual psychotherapy, and family therapy. Currently, the best results have been shown with weight restoration accompanied by family therapy for patients with adolescent-onset anorexia nervosa and individual therapy for patients with onset after 18 years of age. Inpatient treatment is often required.

                                                                                                                                                                A. Propylthiouracil is used to treat hyperthyroidism, not anorexia nervosahttps://smartypance.com/lessons/ear-disorders/inner-ear-pearls/acoustic-neuroma/

                                                                                                                                                                B. Hormone replacement is not indicated for the amenorrhea of anorexia nervosa, but nutritional support may help.
                                                                                                                                                                D. Antidepressant therapy may be useful in bulimia nervosa

                                                                                                                                                                10. A 52-year-old female presents with complaints of intermittent episodes of dizziness, tinnitus, and hearing loss in the right ear for 6 months. She describes the dizziness as the “room spinning around her,” with the episodes typically lasting for 2 to 4 hours. Physical examination reveals horizontal nystagmus and right ear hearing loss, but the remainder of the examination is unremarkable. Which of the following is the most likely diagnosis?

                                                                                                                                                                A. Acute labyrinthitis
                                                                                                                                                                B. Positional vertigo
                                                                                                                                                                C. Acoustic neuroma
                                                                                                                                                                D. Ménière’s syndrome

                                                                                                                                                                Click here to see the answer

                                                                                                                                                                D. Ménière’s syndrome uhttps://smartypance.com/lessons/ear-disorders/inner-ear-pearls/vertigo-reeldx294/sually presents with episodes of vertigo that last from 1 to 8 hours, sensorineural hearing loss and tinnitus.

                                                                                                                                                                A. Acute labyrinthitis typically presents with an acute onset of continuous vertigo that lasts several days to a week and is associated with nausea and vomiting. It does not have any associated auditory or neurologic symptoms.

                                                                                                                                                                B. Positional vertigo occurs following changes in head positioning with very brief, less than 1 minute, episodes. Nystagmus occurs following the position change.
                                                                                                                                                                C. Acoustic neuroma typically presents with hearing loss and tinnitus. The neuroma grows slowly and central compensatory mechanisms can prevent or minimize the vertigo. Vertigo, when present, is continuous and not episodic.

                                                                                                                                                                Looking for all the podcast episodes?

                                                                                                                                                                This FREE series is limited to every other episode, you can download and enjoy the complete audio series by joining The PANCE and PANRE Exam Academy + SMARTYPANCE

                                                                                                                                                                I will be releasing new episodes every few weeks. The Academy is discounted, so sign up now.

                                                                                                                                                                Resources and Links From The Show
                                                                                                                                                                • My list of recommended PANCE and PANRE review books
                                                                                                                                                                • Download the FREE PANCE and PANRE Blueprint Checklist
                                                                                                                                                                • Sign up for the FREE daily PANCE and PANRE email series
                                                                                                                                                                • Join the Smarty PANCE NCCPA Content Blueprint Website + The PA Life Academy
                                                                                                                                                                • Get 20% of any Picmonic membership by using this link
                                                                                                                                                                • Use Code “PALIFE” and get 10% OFF THE RUTGERS PANCE AND PANRE REVIEW COURSE
                                                                                                                                                                • This Podcast is also available on iTunes and Stitcher Radio for Android
                                                                                                                                                                  1. iTunes: The Audio PANCE AND PANRE Podcast iTunes
                                                                                                                                                                  2. Stitcher Radio: The Audio PANCE and PANRE Podcast Stitcher
                                                                                                                                                                  3. Download The Content Blueprint Checklist

                                                                                                                                                                    Follow this link to download your FREE copy of the Content Blueprint Checklist

                                                                                                                                                                    Print it up and start crossing out the topics you understand, marking the ones you don’t and making notes of key terms you should remember. The PDF version is interactive and linked directly to the individual lessons on SMARTY PANCE.

                                                                                                                                                                    Download

                                                                                                                                                                    19 min
                                                                                                                                                                  4. Podcast Episode 65: Hepatitis B Breakdown With Joe Gilboy PA-C

                                                                                                                                                                    NCCPA™ PANCE Content Blueprint – The ABC’s of Hepatitis +The Hepatitis B Breakdown

                                                                                                                                                                    Welcome to episode 65 of the Audio PANCE and PANRE PA Board Review Podcast.

                                                                                                                                                                    In today’s episode, I welcome my friend, exclusive smartypance lecturer, and PA board review extraordinaire Joe Gilboy PA-C who will be breaking down Hepatitis B as you’ve never seen it before.

                                                                                                                                                                    This is a recorded lecture featured on my smartypance.com board review website covering Hepatitis A, B, and C testing with twelve follow up questions at the end.

                                                                                                                                                                    Below you will find an interactive exam to complement the podcast.

                                                                                                                                                                    I hope you enjoy this free audio component to the examination portion of the site. The full board review covers the entire NCCPA Content Blueprint, all indexed, searchable, and now available with Joe’s Gilboy’s priceless lectures.

                                                                                                                                                                    To top it off you can sign up today for the free 60-day board review email series which includes Joe’s audio explanations.

                                                                                                                                                                    If you enjoyed this podcast episode:

                                                                                                                                                                    • You can download and listen to past FREE episodes here, on iTunes, Google Play Music, or Stitcher Radio.
                                                                                                                                                                    • Listen Carefully Then Take The Practice Exam

                                                                                                                                                                      If you can’t see the audio player click here to listen to the full episode.

                                                                                                                                                                      Podcast Episode 65: Hepatitis PANCE/PANRE Podcast Quiz

                                                                                                                                                                      The following questions are linked to NCCPA Content Blueprint lessons from the SMARTYPANCE & PANRE Board Review Website. If you are a member you will be able to log in and view this interactive video lesson.

                                                                                                                                                                      1. A patient presents wanting to be tested to see if they presently have Hepatitis A which labs would you order?

                                                                                                                                                                      a. Anti-HAV (IgG)

                                                                                                                                                                      b. Anti-HAV (IgA)
                                                                                                                                                                      c. Anti-HAV (IgM)
                                                                                                                                                                      d. Anti-HAV (IgE)

                                                                                                                                                                      Click here to see the answer

                                                                                                                                                                      c. Anti-HAV (IgM)

                                                                                                                                                                      2. Which lab result would a PA and an IV drug abuser both have that are positive?

                                                                                                                                                                      a. Anti-HBs

                                                                                                                                                                      b. Anti-HBe
                                                                                                                                                                      c. Anti-HBc
                                                                                                                                                                      d. HBeAg

                                                                                                                                                                      Click here to see the answer

                                                                                                                                                                      a. Anti-HBs

                                                                                                                                                                      3. Which positive lab tells you a person is currently actively infected with hepatitis B?

                                                                                                                                                                      a. HBsAg

                                                                                                                                                                      b. HBsAb
                                                                                                                                                                      c. HBcAg
                                                                                                                                                                      d. HBeAg

                                                                                                                                                                      Click here to see the answer

                                                                                                                                                                      d. HBeAg

                                                                                                                                                                      4. Which of the following lab result would a chronic hepatitis B patient have that is positive?

                                                                                                                                                                      a. HBsAg

                                                                                                                                                                      b. HBsAb
                                                                                                                                                                      c. HBcAg
                                                                                                                                                                      d. HBeAg

                                                                                                                                                                      Click here to see the answer

                                                                                                                                                                      a. HBsAg

                                                                                                                                                                      5. Immunoglobulin is given within two weeks for family members and close contacts when they are exposed to hepatitis A. Which immunoglobulin is given?

                                                                                                                                                                      a. IgM

                                                                                                                                                                      b. IgG
                                                                                                                                                                      c. IgA
                                                                                                                                                                      d. IgE

                                                                                                                                                                      Click here to see the answer

                                                                                                                                                                      b. IgG

                                                                                                                                                                      6. Hepatitis D needs what part of hepatitis B to exist?

                                                                                                                                                                      a. HBsAg

                                                                                                                                                                      b. HBsAb
                                                                                                                                                                      c. HBcAg
                                                                                                                                                                      d. HBeAg

                                                                                                                                                                      Click here to see the answer

                                                                                                                                                                      a. HBsAg

                                                                                                                                                                      7. Hepatitis E is transmitted by which vector?

                                                                                                                                                                      a. IV drug abuse

                                                                                                                                                                      b. Homosexual sex
                                                                                                                                                                      c. Fecal-oral
                                                                                                                                                                      d. Blood transfusion

                                                                                                                                                                      Click here to see the answer

                                                                                                                                                                      c. Fecal-oral

                                                                                                                                                                      8. What is the 1st evidence of infection with hepatitis B?

                                                                                                                                                                      a. HBcAg

                                                                                                                                                                      b. HBeAg
                                                                                                                                                                      c. Anti-HBs
                                                                                                                                                                      d. HBsAg

                                                                                                                                                                      Click here to see the answer

                                                                                                                                                                      c. Anti-HBs

                                                                                                                                                                      9. What is the lab test to indicate a diagnosis of acute hepatitis B?

                                                                                                                                                                      a. Anti-HBs

                                                                                                                                                                      b. Anti-HBe
                                                                                                                                                                      c. Anti-HBc
                                                                                                                                                                      d. HBeAg

                                                                                                                                                                      Click here to see the answer

                                                                                                                                                                      c. Anti-HBc

                                                                                                                                                                      10. What is the lab test that indicates viral replication and infectious Hepatitis B?

                                                                                                                                                                      a. HBcAg

                                                                                                                                                                      b. HBeAg
                                                                                                                                                                      c. Anti-HBs
                                                                                                                                                                      d. HBsAg

                                                                                                                                                                      Click here to see the answer

                                                                                                                                                                      b. HBeAg

                                                                                                                                                                      11. Which of the following is the first sign of a patient with an elevated conjugated bilirubin (direct)?

                                                                                                                                                                      a. Icteric sclera

                                                                                                                                                                      b. Jaundice
                                                                                                                                                                      c. Acholic stool
                                                                                                                                                                      d. Tea-colored urine

                                                                                                                                                                      Click here to see the answer

                                                                                                                                                                      d. Tea-colored urine

                                                                                                                                                                      12. A 52-yo male with upper abdominal pain and an elevated aminotransferase(AST) >10,000 u/l is consistent with which problem?

                                                                                                                                                                      a. Gallstones

                                                                                                                                                                      b. Alcoholic liver disease
                                                                                                                                                                      c. Bile duct stones
                                                                                                                                                                      d. Viral Hepatitis

                                                                                                                                                                      Click here to see the answer

                                                                                                                                                                      d. Viral Hepatitis

                                                                                                                                                                      Looking for all the podcast episodes?

                                                                                                                                                                      This FREE series is limited to every other episode, you can download and enjoy the complete audio series by joining The PANCE and PANRE Exam Academy + SMARTYPANCE

                                                                                                                                                                      I will be releasing new episodes every few weeks. The Academy is discounted, so sign up now.

                                                                                                                                                                      Resources and Links From The Show
                                                                                                                                                                      • My list of recommended PANCE and PANRE review books
                                                                                                                                                                      • Download the FREE PANCE and PANRE Blueprint Checklist
                                                                                                                                                                      • Sign up for the FREE daily PANCE and PANRE email series
                                                                                                                                                                      • Join the Smarty PANCE NCCPA Content Blueprint Website + The PA Life Academy
                                                                                                                                                                      • Get 20% of any Picmonic membership by using this link
                                                                                                                                                                      • Use Code “PALIFE” and get 10% OFF THE RUTGERS PANCE AND PANRE REVIEW COURSE
                                                                                                                                                                      • This Podcast is also available on iTunes and Stitcher Radio for Android
                                                                                                                                                                        1. iTunes: The Audio PANCE AND PANRE Podcast iTunes
                                                                                                                                                                        2. Stitcher Radio: The Audio PANCE and PANRE Podcast Stitcher
                                                                                                                                                                        3. Download The Content Blueprint Checklist

                                                                                                                                                                          Follow this link to download your FREE copy of the Content Blueprint Checklist

                                                                                                                                                                          Print it up and start crossing out the topics you understand, marking the ones you don’t and making notes of key terms you should remember. The PDF version is interactive and linked directly to the individual lessons on SMARTY PANCE.

                                                                                                                                                                          Download

                                                                                                                                                                          23 min
                                                                                                                                                                        4. Episode 63: The Audio PANCE and PANRE – Ten Mixed NCCPA™ Content Blueprint Multiple Choice Questions

                                                                                                                                                                          Ten Mixed NCCPA™ PANCE Content Blueprint Multiple Choice Questions

                                                                                                                                                                          Welcome to episode 63 of the FREE Audio PANCE and PANRE Physician Assistant Board Review Podcast.

                                                                                                                                                                          Join me as I cover ten PANCE and PANRE Board review questions from the SMARTYPANCE course content following the NCCPA™ content blueprint (download the FREE cheat sheet).

                                                                                                                                                                          This week we will be covering ten general board review questions based on the NCCPA PANCE and PANRE Content Blueprint. 

                                                                                                                                                                          Below you will find an interactive exam to complement the podcast.

                                                                                                                                                                          I hope you enjoy this free audio component to the examination portion of this site. The full board review includes over 2,000 interactive board review questions and is available to all members of the PANCE and PANRE Academy and SMARTYPANCE which are now bundled together into one very low price.

                                                                                                                                                                          • You can download and listen to past FREE episodes here, on iTunes, on Google Play Music or Stitcher Radio.
                                                                                                                                                                          • You can listen to the latest episode, take an interactive quiz and download your results below.
                                                                                                                                                                          • Listen Carefully Then Take The Practice Exam

                                                                                                                                                                            If you can’t see the audio player click here to listen to the full episode.

                                                                                                                                                                            Episode 63 – General PANCE/PANRE Podcast Quiz

                                                                                                                                                                            The following 10 questions are linked to NCCPA Content Blueprint lessons from the SMARTYPANCE and PANRE Board review website. If you are a member you will be able to log in and view this interactive video content.

                                                                                                                                                                            1. A 24-year-old male presents complaining of a 9-month history of increasing shortness of breath, dyspnea on exertion, and a cough productive of white sputum, mostly in the mornings. He denies orthopnea, PND, peripheral edema, fever, chills, night sweats, recent changes in weight, palpitations, chest pain, food intolerances, or other complaints. Patient has a history of recurrent lung infections. He states that his father had chronic pulmonary problems and died at age 42 from unknown lung disease. The patient denies smoking, alcohol or illicit drug use. On physical examination, the respiratory rate is 22 breaths per minute, a pulse of 98 bpm, a temperature of 98.7 degrees. Pulmonary exam reveals end-expiratory wheezes bilaterally and hyperresonance to percussion. His cardiac exam is normal. Chest X-ray shows decreased lung markings. ECG is normal. Pulmonary function tests show an FEV1 63% of expected and residual capacity is 123% of expected. Which of the following is the most likely diagnosis?

                                                                                                                                                                            A. Emphysema

                                                                                                                                                                            B. Pulmonary fibrosis
                                                                                                                                                                            C. Ventricular septal defect
                                                                                                                                                                            D. Congestive heart failure

                                                                                                                                                                            Click here to see the answer

                                                                                                                                                                            Answer: A. Emphysema

                                                                                                                                                                            This person has an obstructive lung disease based on PFTs. Emphysema is the most likely diagnosis and may be related to alpha-1 antitrypsin deficiency based on family history and lack of smoking history and young age.

                                                                                                                                                                            Emphysema is covered as part of the NCCPA Pulmonary Blueprint (12%)

                                                                                                                                                                            B. The PFTs from a person with pulmonary fibrosis would be consistent with a restrictive pattern. This patient has an obstructive pattern of lung disease.

                                                                                                                                                                            C. Ventricular septal defect will have a systolic murmur associated with it.
                                                                                                                                                                            D. Congestive heart failure might explain some of the symptoms of this patient (increasing shortness of breath and DOE), he denies other common symptoms, such as orthopnea and peripheral edema. CHF should not result in changes in the PFTs.

                                                                                                                                                                            2. A male patient complains of chronic dysuria, frequency, and urgency with associated perineal pain. The most likely diagnosis is

                                                                                                                                                                            A. cystitis

                                                                                                                                                                            B. gonococcal urethritis
                                                                                                                                                                            C. epididymitis
                                                                                                                                                                            D. prostatitis

                                                                                                                                                                            Click here to see the answer

                                                                                                                                                                            Answer: D. prostatitis

                                                                                                                                                                            Some patients are asymptomatic, but low back or perineal pain, fever, chills, and irritative urinary symptoms are common in prostatitis.

                                                                                                                                                                            Prostatitis is covered as part of the NCCPA PANCE Genitourinary Blueprint

                                                                                                                                                                            A. Cystitis is characterized by dysuria without urethral discharge.

                                                                                                                                                                            B. Initially, there is burning on urination and serous or milky discharge in gonococcal urethritis.
                                                                                                                                                                            C. Epididymitis is characterized by dysuria, unilateral scrotal pain, and swelling.

                                                                                                                                                                            3. Which of the following preventive strategies against osteoporosis-associated vertebral fractures has a known side effect of increasing the incidence of hot flashes when used in a perimenopausal female?

                                                                                                                                                                            A. Calcitonin (Miacalcin) nasal spray

                                                                                                                                                                            B. Alendronate (Fosamax)
                                                                                                                                                                            C. Estrogen/progesterone (Prempro)replacement
                                                                                                                                                                            D. Raloxifene (Evista)

                                                                                                                                                                            Osteoporosis is covered as part of the PANCE Musculoskeletal Blueprint

                                                                                                                                                                            Click here to see the answer

                                                                                                                                                                            Answer: D. Raloxifene (Evista)

                                                                                                                                                                            Raloxifene has effects on bone turnover and bone mass and has been shown to decrease vertebral fractures. It has anti-estrogen effects on the non-skeletal portions of the body and increases hot flashes in perimenopausal females.

                                                                                                                                                                            A. Calcitonin does not have any estrogen effects on the body and serves as an analgesic when used in the management of vertebral fractures.

                                                                                                                                                                            B. Alendronate is a bisphosphonate that does not have any hormonal effects on the body.
                                                                                                                                                                            C. Estrogen/progesterone replacement has the benefit of maintaining bone and decreasing vertebral fractures but it would improve perimenopausal hot flashes.

                                                                                                                                                                            4. A 70-year-old presents with a headache and neck stiffness. On physical exam, the patient is febrile, Kernig’s sign is present, and no rash is noted. A spinal tap reveals a white count of 250/cm3 with 100% neutrophils, total protein 250mg/dL, and glucose 35 mg/dL. Which of the following is the most appropriate treatment?

                                                                                                                                                                            A. Acyclovir (Zovirax)

                                                                                                                                                                            B. Fluconazole (Diflucan)
                                                                                                                                                                            C. Ampicillin and ceftriaxone (Rocephin)
                                                                                                                                                                            D. Penicillin and chloramphenicol (Chloromycetin)

                                                                                                                                                                            Bacterial meningitis is covered as part of the PANCE Neurology Blueprint

                                                                                                                                                                            Click here to see the answer

                                                                                                                                                                            Answer: C. Ampicillin and ceftriaxone (Rocephin)

                                                                                                                                                                            Ampicillin and ceftriaxone are used to treat bacterial meningitis, secondary to Listeria monocytogenes, which is common in the elderly. Ceftriaxone will cover other common etiologic agents such as Streptococcal pneumonia

                                                                                                                                                                            A. Acyclovir is used to treat meningitis secondary to herpes. Viral meningitis presents with an increased number of lymphocytes and elevated glucose in the CSF.

                                                                                                                                                                            B. Fluconazole is used to treat fungal meningitis. Fungal meningitis, typically noted in immunocompromised hosts, presents with an increased number of lymphocytes in the CSF.
                                                                                                                                                                            D. Penicillin and chloramphenicol is used to treat bacterial meningitis, secondary to Neisseria meningitidis. Bacterial meningitis due to N

                                                                                                                                                                            5. A 45-year-old patient with type 1 diabetes mellitus is being screened for diabetic nephropathy. Which of the following urinalysis findings is most consistent with early diabetic nephropathy?

                                                                                                                                                                            A. Microalbuminuria

                                                                                                                                                                            B. Red cell casts
                                                                                                                                                                            C. White cell casts
                                                                                                                                                                            D. Renal epithelial cells

                                                                                                                                                                            Diabetic neuropathy is covered as part of the PANCE Endocrinology Blueprint

                                                                                                                                                                            Click here to see the answer

                                                                                                                                                                            Answer: A. Microalbuminuria

                                                                                                                                                                            Microalbuminuria is most consistent with early diabetic neuropathy.

                                                                                                                                                                            B. Red cell casts are more indicative of acute glomerular nephritis.

                                                                                                                                                                            C. White cell casts are more consistent with acute pyelonephritis.
                                                                                                                                                                            D. A few renal epithelial cells normally may be found in the urine.

                                                                                                                                                                            6. A 74-year-old female is being treated for mild hypertension. She is found at home with right hemiparesis and brought to the emergency department. Her daughter states that the patient fell in her kitchen 2 days ago, but had no complaints at that time. She did state that her mother sounded a little confused this morning. The patient’s left pupil is dilated. Which of the following diagnostic studies should be ordered first?

                                                                                                                                                                            A. MRI of the brain

                                                                                                                                                                            B. CT scan of the brain
                                                                                                                                                                            C. Skull x-ray
                                                                                                                                                                            D. Lumbar puncture

                                                                                                                                                                            Click here to see the answer

                                                                                                                                                                            Answer:  B. CT scan of the brain

                                                                                                                                                                            This patient presents with a history of minor trauma and progressive neurological abnormalities consistent with subdural hematoma. Diagnosis would be confirmed by CT scan, which is less expensive and more sensitive for blood than an MRI.

                                                                                                                                                                            Intracranial Hemorrhage is covered as part of the PANCE Neurology Blueprint

                                                                                                                                                                            C. Skull x-rays would not be helpful because they evaluate bony, not soft tissue, injury.

                                                                                                                                                                            D. A lumbar puncture is contraindicated because of the potential for brain herniation.

                                                                                                                                                                            7. A post-op patient has signs and symptoms highly suggestive of a pulmonary embolism. The results of the CT scan of the lung is nondiagnostic. What is the most appropriate next step in the evaluation?

                                                                                                                                                                            A. Ventilation-perfusion (V/Q) scan

                                                                                                                                                                            B. Ultrasound of the legs
                                                                                                                                                                            C. Echocardiography
                                                                                                                                                                            D. D-dimer

                                                                                                                                                                            Pulmonary embolism and is part of the PANCE Pulmonary Blueprint

                                                                                                                                                                            Click here to see the answer

                                                                                                                                                                            Answer: B. Ultrasound of the legs

                                                                                                                                                                            In a patient with a high likelihood of pulmonary embolism or an inpatient, as in this case, ultrasound of the legs would be the next diagnostic step after a nondiagnostic CT.

                                                                                                                                                                            A. Ventilation-perfusion scans are performed prior to the CT scan of the chest and would not likely add additional information to this clinical scenario.

                                                                                                                                                                            C. Although echocardiography may show right ventricular free wall hypokinesis with normal motion of the apex suggestive of pulmonary embolism, more than 50% of patients with a pulmonary embolism will have normal echocardiography. Echocardiography is not used in the diagnosis of inpatients.
                                                                                                                                                                            D. In a post-op patient, a d-dimer will be positive regardless of the presence or absence of a pulmonary embolism.

                                                                                                                                                                            8. Seizures that first manifest in early to middle adult life should be considered suspicious of which of the following causes?

                                                                                                                                                                            A. Cerebrovascular disease

                                                                                                                                                                            B. Encephalitis
                                                                                                                                                                            C. Tumor
                                                                                                                                                                            D. Idiopathic epilepsy

                                                                                                                                                                            Seizure disorders are covered as part of the PANCE Neurology Blueprint

                                                                                                                                                                            Click here to see the answer

                                                                                                                                                                            Answer: C. Tumor

                                                                                                                                                                            Seizures that develop during adolescence and adult life are predominantly due to tumor, trauma, drug use, or alcohol withdrawal.

                                                                                                                                                                            9. Which of the following medications used in the treatment of supraventricular tachycardia is able to cause sinus arrest and asystole for a few seconds while it breaks the paroxysmal supraventricular tachycardia?

                                                                                                                                                                            A. Digoxin (Lanoxin)

                                                                                                                                                                            B. Adenosine (Adenocard)
                                                                                                                                                                            C. Verapamil (Calan)
                                                                                                                                                                            D. Quinidine (Quinaglute)

                                                                                                                                                                            Paroxysmal supraventricular tachycardia is covered as part of the PANCE Cardiology Blueprint

                                                                                                                                                                            Click here to see the answer

                                                                                                                                                                            Answer: B. Adenosine (Adenocard)

                                                                                                                                                                            Adenosine is an endogenous nucleoside that results in profound (although transient) slowing of the AV conduction and sinus node discharge rate. This agent has a very short half-life of 6 seconds.

                                                                                                                                                                            A. Digoxin is not used for the acute termination of supraventricular tachycardia.

                                                                                                                                                                            C. Although verapamil may be used for the termination of acute supraventricular tachycardia, it does not lead to sinus arrest in therapeutic doses.
                                                                                                                                                                            D. Quinidine is rarely used today and is not indicated for the termination of supraventricular tachycardia.

                                                                                                                                                                            10. A 32-year-old presents with a 3-day history of diarrhea. The patient denies blood, mucus, or night awakening with diarrhea. He recently returned from a business trip to Canada. On physical examination, the patient is afebrile and vital signs reveal BP 115/80, the pulse is 76, and respirations are 14. The abdominal examination reveals hyperactive bowel sounds but is otherwise unremarkable. Which of the following is the most appropriate initial intervention?

                                                                                                                                                                            A. Stool for culture, ova, and parasites

                                                                                                                                                                            B. Proctosigmoidoscopy
                                                                                                                                                                            C. Metronidazole (Flagyl)
                                                                                                                                                                            D. Supportive treatment

                                                                                                                                                                            Infectious and Noninfectious Diarrhea are covered as part of the NCCPA PANCE GI and Nutrition Blueprint

                                                                                                                                                                            Click here to see the answer

                                                                                                                                                                            Answer: D. Supportive treatment

                                                                                                                                                                            Symptomatic treatment, including dietary management and over-the-counter antidiarrheals, is indicated for afebrile patients with watery diarrhea of less than 5 days duration.

                                                                                                                                                                            A. Stool culture and examination for ova and parasites are indicated when diarrhea has persisted longer than 3 weeks or is associated with abdominal pain, fever, and/or bloody stools.

                                                                                                                                                                            B. Proctosigmoidoscopy is indicated when inflammatory bowel disease is suspected on the basis of fever, bloody diarrhea, or abdominal pain.
                                                                                                                                                                            C. Metronidazole is indicated with a confirmed diagnosis of Giardia lamblia or amebic disease.

                                                                                                                                                                            Looking for all the podcast episodes?

                                                                                                                                                                            This FREE series is limited to every other episode, you can download and enjoy the complete audio series by joining The PANCE and PANRE Exam Academy + SMARTYPANCE

                                                                                                                                                                            I will be releasing new episodes every few weeks. The Academy is discounted, so sign up now.

                                                                                                                                                                            Resources and Links From The Show
                                                                                                                                                                            • My list of recommended PANCE and PANRE review books
                                                                                                                                                                            • Download the FREE PANCE and PANRE Blueprint Checklist
                                                                                                                                                                            • Sign up for the FREE daily PANCE and PANRE email series
                                                                                                                                                                            • Join the Smarty PANCE NCCPA Content Blueprint Website + The PA Life Academy
                                                                                                                                                                            • Get 20% of any Picmonic membership by using this link
                                                                                                                                                                            • Use Code “PALIFE” and get 10% OFF THE RUTGERS PANCE AND PANRE REVIEW COURSE
                                                                                                                                                                            • This Podcast is also available on iTunes and Stitcher Radio for Android
                                                                                                                                                                              1. iTunes: The Audio PANCE AND PANRE Podcast iTunes
                                                                                                                                                                              2. Stitcher Radio: The Audio PANCE and PANRE Podcast Stitcher
                                                                                                                                                                              3. Download The Content Blueprint Checklist

                                                                                                                                                                                Follow this link to download your FREE copy of the Content Blueprint Checklist

                                                                                                                                                                                Print it up and start crossing out the topics you understand, marking the ones you don’t and making notes of key terms you should remember. The PDF version is interactive and linked directly to the individual lessons on SMARTY PANCE.

                                                                                                                                                                                Download

                                                                                                                                                                                18 min
                                                                                                                                                                              4. Episode 61: The Audio PANCE and PANRE – Ten Mixed NCCPA™ Content Blueprint Multiple Choice Questions
                                                                                                                                                                                Ten Mixed NCCPA™ Content Blueprint Multiple Choice Questions

                                                                                                                                                                                Welcome to episode 61 of the FREE Audio PANCE and PANRE Physician Assistant Board Review Podcast.

                                                                                                                                                                                Join me as I cover ten PANCE and PANRE Board review questions from the SMARTYPANCE course content following the NCCPA™ content blueprint (download the FREE cheat sheet).

                                                                                                                                                                                This week we will be covering ten general board review questions based on the NCCPA PANCE and PANRE Content Blueprint. 

                                                                                                                                                                                Below you will find an interactive exam to complement the podcast.

                                                                                                                                                                                I hope you enjoy this free audio component to the examination portion of this site. The full board review includes over 2,000 interactive board review questions and is available to all members of the PANCE and PANRE Academy and SMARTYPANCE which are now bundled together into one very low price.

                                                                                                                                                                                • You can download and listen to past FREE episodes here, on iTunes, on Google Play Music or Stitcher Radio.
                                                                                                                                                                                • You can listen to the latest episode, take an interactive quiz and download your results below.
                                                                                                                                                                                • Listen Carefully Then Take The Practice Exam

                                                                                                                                                                                  If you can’t see the audio player click here to listen to the full episode.

                                                                                                                                                                                  Episode 5 – General PANCE/PANRE Podcast Quiz

                                                                                                                                                                                  The following 10 questions are linked to NCCPA Content Blueprint lessons from the SMARTYPANCE and PANRE Board review website. If you are a member you will be able to log in and view this interactive video content.

                                                                                                                                                                                  1. An 18-year-old male presents with pain in his wrist after he fell off of a moving motorcycle. Physical examination reveals tenderness in the anatomic snuffbox. No fracture is noted on plain radiography of the wrist. Which of the following is the recommended treatment for this patient?

                                                                                                                                                                                  A. An ace wrap of the wrist

                                                                                                                                                                                  B. Closed reduction of the fracture site
                                                                                                                                                                                  C. Thumb spica cast application
                                                                                                                                                                                  D. Open reduction of the fracture site

                                                                                                                                                                                  Click here to see the answer

                                                                                                                                                                                  Answer: C. Thumb spica cast application

                                                                                                                                                                                  Even with normal initial radiographs, patients with a consistent history and tenderness in the anatomical snuffbox are treated as a stable fracture with immobilization in a thumb spica cast. Casting is recommended for all presumed nondisplaced scaphoid fractures.

                                                                                                                                                                                  Scaphoid fractures covered in fractures and dislocation of the forearm, wrist, and hand and are part of the NCCPA Endocrinology Musculoskeletal Blueprint (10%)

                                                                                                                                                                                  2. A solitary pulmonary nodule is found on a pre-employment screening chest x-ray in a 34-year-old non-smoking male. There are no old chest x-rays to compare. Which of the following is the most appropriate next step in the evaluation?

                                                                                                                                                                                  A. CT scan of the chest

                                                                                                                                                                                  B. Needle biopsy of the lesion
                                                                                                                                                                                  C. Positron emission tomography of the chest
                                                                                                                                                                                  D. Fiberoptic bronchoscopy

                                                                                                                                                                                  Solitary pulmonary nodules are covered as part of the NCCPA PANCE Blueprint Pulmonary (12%) Content Blueprint (12%)

                                                                                                                                                                                  Click here to see the answer

                                                                                                                                                                                  Answer: A. CT scan of the chest

                                                                                                                                                                                  In the absence of old x-rays in a nonsmoking individual less than 35 years old, CT scan of the chest is the next step in the evaluation of a solitary pulmonary nodule.

                                                                                                                                                                                  B. A needle biopsy would be indicated for a person greater than 35 years old and/or with a history of smoking to evaluate a solitary pulmonary nodule.

                                                                                                                                                                                  C. Positron emission tomography (PET scan) would be indicated if the CT scan was nonconclusive.
                                                                                                                                                                                  D. Fiberoptic bronchoscopy would be indicated only in the presence of a history of tobacco use or if the lesion was suggestive of malignancy.

                                                                                                                                                                                  3. Early clues to impending delirium tremens include

                                                                                                                                                                                  A. agitation and decreased cognition.

                                                                                                                                                                                  B. visual hallucinations and diaphoresis.
                                                                                                                                                                                  C. autonomic hyperactivity and dehydration.
                                                                                                                                                                                  D. mental confusion and sensory hyperacuity.

                                                                                                                                                                                  Delirium tremens is covered as part of the NCCPA Psychiatry content blueprint (6%) under the topic of withdrawal

                                                                                                                                                                                  Click here to see the answer

                                                                                                                                                                                  Answer: A. agitation and decreased cognition.

                                                                                                                                                                                  Anxiety, decreased cognition, tremulousness, increasing irritability, and hyperactivity are common early clues to impending delirium tremens.

                                                                                                                                                                                  Mental confusion, tremor, sensory hyperacuity, visual hallucinations, autonomic hyperactivity, diaphoresis, dehydration, electrolyte disturbances, seizures, and cardiovascular abnormalities are common signs and/or symptoms of full-blown delirium tremens.

                                                                                                                                                                                  4. Dental caries are caused by which of the following organisms?

                                                                                                                                                                                  A. Streptococcus mutans

                                                                                                                                                                                  B. Streptococcus pyogenes
                                                                                                                                                                                  C. Staphylococcus epidermidis
                                                                                                                                                                                  D. Staphylococcus aureus

                                                                                                                                                                                  Dental caries are covered as part of the NCCPA EENT Content Blueprint (9%) under diseases of the teeth and gums

                                                                                                                                                                                  Click here to see the answer

                                                                                                                                                                                  Answer: A. Streptococcus mutans

                                                                                                                                                                                  Streptococcus mutans is the principal organism that helps to demineralize the enamel.

                                                                                                                                                                                  5. The most definitive treatment for primary enuresis is

                                                                                                                                                                                  A. oxybutynin chloride (Ditropan).

                                                                                                                                                                                  B. imipramine (Tofranil).
                                                                                                                                                                                  C. trimethoprim-sulfamethoxazole (Bactrim).
                                                                                                                                                                                  D. desmopressin (DDAVP)

                                                                                                                                                                                  Primary enuresis is covered under incontinence as part of the NCCPA Genitourinary Content Blueprint (6%)

                                                                                                                                                                                  Click here to see the answer

                                                                                                                                                                                  Answer: D. desmopressin (DDAVP)

                                                                                                                                                                                  Intranasal desmopressin is effective in 50% of patients treated and is the treatment of choice.

                                                                                                                                                                                  A. Oxybutynin chloride is used for bladder spasms. It cannot be used for children under 5 years of age and is not indicated in primary enuresis.

                                                                                                                                                                                  B. Imipramine is an older form of treatment that is moderately effective, but many patients relapse when therapy is stopped. This is no longer considered the treatment of choice.
                                                                                                                                                                                  C. TMP-SMX is indicated for urinary tract infections that may cause secondary enuresis, but it is not used in primary enuresis.

                                                                                                                                                                                  6. A 47-year-old female presents to the clinic with complaints of prolonged, heavy menses that have been getting progressively worse for 3 years. She denies any pain. On physical examination, enlargement of the uterus with multiple smooth, spherical, firm masses is noted. A CBC is consistent with a mild anemia. Which of the following is the most likely diagnosis?

                                                                                                                                                                                  A. Leiomyoma

                                                                                                                                                                                  B. Adenomyosis
                                                                                                                                                                                  C. Endometriosis
                                                                                                                                                                                  D. Endometrial polyps

                                                                                                                                                                                  Click here to see the answer

                                                                                                                                                                                  Leiomyoma is covered as part of the NCCPA Reproductive Content Blueprint (8%)

                                                                                                                                                                                  Answer:  A. Leiomyoma

                                                                                                                                                                                  Abnormal uterine bleeding and irregular enlargement of the uterus are most consistent with leiomyoma. Pain is rarely present unless vascular compromise occurs.

                                                                                                                                                                                  B. While adenomyosis may present with hypermenorrhea, dysmenorrhea is often also present. Physical examination would reveal the presence of diffuse globular uterine enlargement, not the irregular enlargement as noted in the case presented.

                                                                                                                                                                                  C. Endometriosis presents with dyspareunia, dysmenorrhea, and infertility. If the pelvic exam were abnormal, uterine findings would include tender nodules in the cul de sac, not the uterus.
                                                                                                                                                                                  D. While endometrial polyps are compatible with the history of abnormal uterine bleeding, the uterus would be normal size without the irregular enlargement noted in the case presented.

                                                                                                                                                                                  7. Which of the following is the laboratory test that marks recovery from Hepatitis B infection and non-infectivity?

                                                                                                                                                                                  A. Hepatitis B surface antibody(anti-HBs)

                                                                                                                                                                                  B. Hepatitis B surface antigen (HBsAg)
                                                                                                                                                                                  C. Hepatitis B core antigen (HBcAg)
                                                                                                                                                                                  D. Hepatitis A antibody (anti-HAV)

                                                                                                                                                                                  Hepatitis B serology is covered as part of acute and chronic hepatitis and is part of the NCCPA GI and Nutrition Content Blueprint (10%)

                                                                                                                                                                                  Click here to see the answer

                                                                                                                                                                                  Answer: A. Hepatitis B surface antibody(anti-HBs)

                                                                                                                                                                                  Specific antibody to HBsAg appears in most individuals after clearance of HBsAg which indicates recovery from hepatitis B infection, non-infectivity, and immunity.

                                                                                                                                                                                  B. This test establishes infection with HBV and implies infectivity.

                                                                                                                                                                                  C. Presence of the hepatitis B core antigen reflects active infection.
                                                                                                                                                                                  D. Patients who have immunity to hepatitis A do not have immunity to hepatitis B.

                                                                                                                                                                                  8. A 36-year-old woman admits that her husband has abused her for over ten years. You should inform the woman that she is at most risk for injury or death

                                                                                                                                                                                  A. just before a holiday.

                                                                                                                                                                                  B. just after leaving an abusive spouse.
                                                                                                                                                                                  C. when an abusive spouse arrives home after work.
                                                                                                                                                                                  D. when an abusive spouse has been drinking heavily.

                                                                                                                                                                                  Domestic violence is covered as part of the NCCPA Psychiatry Content Blueprint (6%)

                                                                                                                                                                                  Click here to see the answer

                                                                                                                                                                                  Answer: B. just after leaving an abusive spouse.

                                                                                                                                                                                  Women are more likely to be assaulted or murdered when attempting to report the abuse or leave the abusive relationship; up to 75% of domestic assaults occur after separation.

                                                                                                                                                                                  9. A patient presents with an acutely painful and cold left leg. Distal pulses are absent. Leg is cyanotic. There are no signs of gangrene or other open lesions. Symptoms occurred one hour ago. Which of the following treatments is most appropriate?

                                                                                                                                                                                  A. Vena cava filter

                                                                                                                                                                                  B. Embolectomy
                                                                                                                                                                                  C. Amputation
                                                                                                                                                                                  D. Aspirin

                                                                                                                                                                                  Arterial embolism/thrombosis is covered as part of the NCCPA Cardiology Content Blueprint (16%)

                                                                                                                                                                                  Click here to see the answer

                                                                                                                                                                                  Answer: B. Embolectomy

                                                                                                                                                                                  Embolectomy within 4 to 6 hours is the treatment of choice.

                                                                                                                                                                                  A. Vena cava filters are used in the management of venous thromboembolic disease when anticoagulation cannot be done.

                                                                                                                                                                                  C. Amputation is done only when no viable tissue is present. Cutting off a viable limb is never a good idea.
                                                                                                                                                                                  D. Aspirin is used in the prevention and treatment of coronary disease and has no role in the treatment of peripheral arterial embolism.

                                                                                                                                                                                  10. A 53-year-old male is seen in the emergency department following a motor vehicle collision in which his knee impacted against the dashboard. The patient has a posterior knee dislocation that is promptly reduced in the emergency department. The patient currently has a palpable pulse in the dorsalis pedis and posterior tibial areas. Which of the following studies is mandatory?

                                                                                                                                                                                  A. Anterior plain film of knee

                                                                                                                                                                                  B. Sunrise view of the knee
                                                                                                                                                                                  C. Measurement of compartment pressures
                                                                                                                                                                                  D. Angiography

                                                                                                                                                                                  Fractures and dislocations of the knee are covered as part of the NCCPA Musculoskeletal Content Blueprint (10%)

                                                                                                                                                                                  Click here to see the answer

                                                                                                                                                                                  Answer: D. Angiography

                                                                                                                                                                                  The popliteal artery is at risk for injury whenever a patient sustains a posterior dislocation of the knee and should be evaluated with an arteriogram despite the presence of pedal pulses.

                                                                                                                                                                                  C. Compartment pressures are performed in cases of suspected compartment syndrome, not to determine the patency of the popliteal artery.

                                                                                                                                                                                  Looking for all the podcast episodes?

                                                                                                                                                                                  This FREE series is limited to every other episode, you can download and enjoy the complete audio series by joining The PANCE and PANRE Exam Academy + SMARTYPANCE

                                                                                                                                                                                  I will be releasing new episodes every few weeks. The Academy is discounted, so sign up now.

                                                                                                                                                                                  Resources and Links From The Show
                                                                                                                                                                                  • My list of recommended PANCE and PANRE review books
                                                                                                                                                                                  • Download the FREE PANCE and PANRE Blueprint Checklist
                                                                                                                                                                                  • Sign up for the FREE daily PANCE and PANRE email series
                                                                                                                                                                                  • Join the Smarty PANCE NCCPA Content Blueprint Website + The PA Life Academy
                                                                                                                                                                                  • Get 20% of any Picmonic membership by using this link
                                                                                                                                                                                  • Use Code “PALIFE” and get 10% OFF THE RUTGERS PANCE AND PANRE REVIEW COURSE
                                                                                                                                                                                  • This Podcast is also available on iTunes and Stitcher Radio for Android
                                                                                                                                                                                    1. iTunes: The Audio PANCE AND PANRE Podcast iTunes
                                                                                                                                                                                    2. Stitcher Radio: The Audio PANCE and PANRE Podcast Stitcher
                                                                                                                                                                                    3. Download The Content Blueprint Checklist

                                                                                                                                                                                      Follow this link to download your FREE copy of the Content Blueprint Checklist

                                                                                                                                                                                      Print it up and start crossing out the topics you understand, marking the ones you don’t and making notes of key terms you should remember. The PDF version is interactive and linked directly to the individual lessons on SMARTY PANCE.

                                                                                                                                                                                      Download

                                                                                                                                                                                      15 min
                                                                                                                                                                                    4. Episode 59: Emergency Medicine EOR – The Audio PANCE and PANRE Board Review Podcast

                                                                                                                                                                                      The Audio PANCE/PANRE PA Board Review Podcast

                                                                                                                                                                                      Welcome to episode 59 of the FREE Audio PANCE and PANRE Physician Assistant Board Review Podcast.

                                                                                                                                                                                      Join me as I cover ten Emergency Medicine End of Rotation Exam (EOR) review questions from the SMARTYPANCE course content following the NCCPA™ and PAEA content blueprint (download the FREE cheat sheet).

                                                                                                                                                                                      This week we will be covering ten emergency medicine end of rotation exam questions based on the NCCPA PANCE and PANRE Content Blueprint. 

                                                                                                                                                                                      Below you will find an interactive exam to complement the podcast.

                                                                                                                                                                                      I hope you enjoy this free audio component to the examination portion of this site. The full board review includes over 2,000 interactive board review questions and is available to all members of the PANCE and PANRE Academy and SMARTYPANCE which are now bundled together into one very low price.

                                                                                                                                                                                      • You can download and listen to past FREE episodes here, on iTunes, on Google Play Music or Stitcher Radio.
                                                                                                                                                                                      • You can listen to the latest episode, take an interactive quiz and download your results below.
                                                                                                                                                                                      • Members can take Emergency medicine EOR 1 (200 questions) and Emergency Medicine EOR 2 (184 questions)
                                                                                                                                                                                      • Listen Carefully Then Take The Practice Exam

                                                                                                                                                                                        If you can’t see the audio player click here to listen to the full episode.

                                                                                                                                                                                        Episode 59 – Emergency Medicine EOR Podcast Quiz

                                                                                                                                                                                        The following 10 questions are linked to NCCPA Content Blueprint lessons from the SMARTYPANCE and PANRE Board review website. If you are a member you will be able to log in and view this interactive video content.

                                                                                                                                                                                        1. During a baseball game, a 22-year-old college student is hit in the right eye by a baseball. He complains of blurry vision in that eye. On physical exam, the physician assistant notes proptosis of the right eye and limitation of movement in all directions. On CT scan, which of the following is most likely to be seen?

                                                                                                                                                                                        A. Fracture of the medial orbital wall

                                                                                                                                                                                        B. Prolapse of orbital soft tissue
                                                                                                                                                                                        C. Hematoma of the orbit
                                                                                                                                                                                        D. Orbital emphysema

                                                                                                                                                                                        Click here to see the answer

                                                                                                                                                                                        Answer: C. Hematoma of the orbit

                                                                                                                                                                                        Orbital hemorrhage into the space surrounding the globe following blunt trauma and rupture of the orbital vessels results in increased ocular pressure, proptosis, visual loss, and limitation of movement in all directions. CT reveals a hematoma.

                                                                                                                                                                                        A. Fracture of the medial orbital wall is associated with diplopia from medial rectus impingement, orbital emphysema, and epistaxis.

                                                                                                                                                                                        B. Prolapse of orbital soft tissue, including inferior rectus muscle, inferior oblique muscle, orbital fat, and connective tissue results in enophthalmos, ptosis, diplopia, anesthesia of the ipsilateral cheek and upper lip, and limitation of upward gaze and is seen with fractures of the orbital floor.
                                                                                                                                                                                        D. Orbital emphysema is seen with fractures of the medial orbital wall or floor of the orbit into the maxillary and ethmoid sinuses respectively. It will not lead to proptosis.

                                                                                                                                                                                        Blowout fractures are covered as part of the NCCPA EENT Content Blueprint which accounts for 9% of your exam.

                                                                                                                                                                                        2. A 29-year-old male presents with a complaint of substernal chest pain for 12 hours. The patient states that the pain radiates to his shoulders and is relieved with sitting forward. The patient admits to recent upper respiratory symptoms. On examination vital signs are BP 126/68, HR 86, RR 20, temp 100.3 degrees F. There is no JVD noted. Heart exam reveals regular rate and rhythm with no S3 or S4. There is a friction rub noted. Lungs are clear to auscultation. EKG shows diffuse ST-segment elevation. What is the treatment of choice for this patient?

                                                                                                                                                                                        A. Pericardiocentesis

                                                                                                                                                                                        B. Nitroglycerin
                                                                                                                                                                                        C. Percutaneous coronary intervention
                                                                                                                                                                                        D. Indomethacin (Indocin)

                                                                                                                                                                                        Click here to see the answer

                                                                                                                                                                                        Answer: D. Indomethacin

                                                                                                                                                                                        Indomethacin, a nonsteroidal anti-inflammatory medication, is the treatment of choice in a patient with acute pericarditis.

                                                                                                                                                                                        A. Pericardiocentesis is the treatment of choice in a patient with a pericardial effusion and cardiac tamponade, there is no evidence of either of these in this patient.

                                                                                                                                                                                        B. Nitroglycerin is indicated in the treatment of chest pain related to angina.
                                                                                                                                                                                        C. Percutaneous coronary intervention is the treatment of choice in a patient with an acute myocardial infarction.

                                                                                                                                                                                        Acute pericarditis is covered the NCCPA Cardiology Content Blueprint which accounts for 16% of your exam.

                                                                                                                                                                                        3. A 19-year-old female presents with a sore throat for nearly two weeks. She complains of fatigue and a low-grade fever. On physical examination, there is cervical, axillary, and inguinal lymphadenopathy, and mild splenomegaly. On review of the blood smear, which of the following would be expected?

                                                                                                                                                                                        A. Atypical lymphocytes

                                                                                                                                                                                        B. Hypersegmented neutrophils
                                                                                                                                                                                        C. Hypochromic red blood cells
                                                                                                                                                                                        D. Schistocytes

                                                                                                                                                                                        Click here to see the answer

                                                                                                                                                                                        Answer: A. Atypical lymphocytes

                                                                                                                                                                                        The hallmark of infectious mononucleosis is the presence of lymphocytosis with atypical large lymphocytes seen in the blood smear. These are larger than normal mature lymphocytes, stain more darkly, and frequently show vacuolated, foamy cytoplasm, and dark chromatin in the nucleus.

                                                                                                                                                                                        B. Hypersegmented neutrophils are seen in vitamin B12 deficiency.

                                                                                                                                                                                        C. Anemia, if seen in mononucleosis, is normocytic and normochromic.
                                                                                                                                                                                        D. Schistocytes are noted in hemolytic anemias.

                                                                                                                                                                                        Mononucleosis as part of the NCCPA Infectious Disease Content Blueprint which accounts for 3% of your exam.

                                                                                                                                                                                        4. A 30-year-old female complains of fatigue, weakness, diminished appetite, weight loss, and syncope. She denies fever, chest or abdominal pain, palpitations, changes in bowel patterns or sleep patterns. Physical examination reveals a thin female, BP 90/65 mmHg, and pulse 80 beats per minute. Pulmonary, cardiovascular, abdominal, and neurologic exam are without abnormalities. Areas of brown and bronze hyperpigmentation are noted on her elbows and the creases of her hands. Which of the following tests will be the most useful in making the diagnosis?

                                                                                                                                                                                        A. Drug screen

                                                                                                                                                                                        B. Urine dipstick
                                                                                                                                                                                        C. Complete blood count
                                                                                                                                                                                        D. Serum creatinine kinase

                                                                                                                                                                                        Click here to see the answer

                                                                                                                                                                                        Answer: D. Serum creatinine kinase

                                                                                                                                                                                        Serum creatinine kinase is the most sensitive test to detect rhabdomyolysis, a serious complication of seizures and hyperthermia related to drug abuse.

                                                                                                                                                                                        A. Although a drug screen may identify specific drugs, the results will not alter the care of this patient.

                                                                                                                                                                                        B. Urine dipstick is not sensitive for myoglobinuria.
                                                                                                                                                                                        C. This patient is at risk for myoglobinuria, and a complete blood count will not alter the treatment.

                                                                                                                                                                                        5. A 15-year-old male was seen last week with complaints of a sore throat, headache, and mild cough. A diagnosis of URI was made and supportive treatment was initiated. He returns today with complaints of worsening cough and increasing fatigue. At this time, chest x-ray reveals bilateral hilar infiltrates. A WBC count is normal and a cold hemagglutinin titer is elevated. The most likely diagnosis is

                                                                                                                                                                                        A. tuberculosis.

                                                                                                                                                                                        B. mycoplasma pneumonia.
                                                                                                                                                                                        C. pneumococcal pneumonia.
                                                                                                                                                                                        D. staphylococcal pneumonia.

                                                                                                                                                                                        Click here to see the answer

                                                                                                                                                                                        Answer: B. mycoplasma pneumonia.

                                                                                                                                                                                        The insidious onset of symptoms, the interstitial infiltrates on chest x-ray, and elevated cold hemagglutinin titer makes this diagnosis the most likely.

                                                                                                                                                                                        A. Most children with pulmonary tuberculosis are asymptomatic with few physical examination findings. The results of the diagnostic studies do not support tuberculosis as the most likely diagnosis.

                                                                                                                                                                                        C. The clinical presentation of bacterial pneumonia in children is variable, but usually involves fever of acute onset. The WBC count is also usually elevated, making this a less likely diagnosis.

                                                                                                                                                                                        Mycoplasma pneumonia is covered as part of the NCCPA Pulmonary Content Blueprint and accounts for 12% of the exam

                                                                                                                                                                                        6. Which of the following clinical manifestations is common in candidal vulvovaginitis?

                                                                                                                                                                                        A. Extreme vulvar irritation

                                                                                                                                                                                        B. Firm, painless ulcer
                                                                                                                                                                                        C. Tender lymphadenopathy
                                                                                                                                                                                        D. Purulent discharge

                                                                                                                                                                                        Click here to see the answer

                                                                                                                                                                                        Answer:  A. Extreme vulvar irritation 

                                                                                                                                                                                        Candida infection presents with pruritus, vulvovaginal erythema, and white, cheese-like (curd) discharge that may be malodorous.

                                                                                                                                                                                        B. A firm painless ulcer is seen in syphilis.

                                                                                                                                                                                        C. Tender lymphadenopathy is associated with bacterial infections and is not a feature of candidal vulvovaginitis.
                                                                                                                                                                                        D. Purulent discharge is noted in gonorrhea.

                                                                                                                                                                                        Vaginitis is covered as part of the NCCPA Reproductive System Content Blueprint and accounts for 8% of the exam

                                                                                                                                                                                        7. A 63-year-old female presents with a complaint of chest pressure for one hour noticed upon awakening. She admits to associated nausea, vomiting, and shortness of breath. 12 lead EKG reveals ST-segment elevation in leads II, III, and AVF. Which of the following is the most likely diagnosis?

                                                                                                                                                                                        A. Aortic dissection

                                                                                                                                                                                        B. Inferior wall myocardial infarction
                                                                                                                                                                                        C. Acute pericarditis
                                                                                                                                                                                        D. Pulmonary embolus

                                                                                                                                                                                        Click here to see the answer

                                                                                                                                                                                        Answer: B. Inferior wall myocardial infarction 

                                                                                                                                                                                        Myocardial infarction often presents with chest pressure and associated nausea and vomiting. ST-segment elevation in leads II, III, and AVF are classic findings seen in acute inferior wall myocardial infarction.

                                                                                                                                                                                        A. A patient with aortic dissection will complain of tearing, ripping pain. EKG is often normal but may reveal left ventricular strain pattern.

                                                                                                                                                                                        C. Acute pericarditis presents with atypical chest pain and diffuse ST-segment elevation.
                                                                                                                                                                                        D. Pulmonary embolism often presents with either no EKG changes or sinus tachycardia. Classically described, rarely seen findings include a large S wave in lead I, a Q wave with T wave inversion in lead III, ST-segment depression in lead II, T wave inversion in leads V1-V4 and a transient right bundle branch block.

                                                                                                                                                                                        Acute myocardial infarction is covered as part of the NCCPA Cardiology Content Blueprint and accounts for 16% of the exam

                                                                                                                                                                                        8. Small grayish vesicles and punched-out ulcers in the posterior pharynx in a child with pharyngitis is representative of which organism?

                                                                                                                                                                                        A. Epstein-Barr virus

                                                                                                                                                                                        B. Group C Streptococcus
                                                                                                                                                                                        C. Coxsackievirus
                                                                                                                                                                                        D. Gonorrhea

                                                                                                                                                                                        Click here to see the answer

                                                                                                                                                                                        Answer: C. Coxsackievirus

                                                                                                                                                                                        Coxsackievirus presents with small grayish vesicles and punched-out ulcers in the posterior pharynx.

                                                                                                                                                                                        A. Epstein-Barr virus presents with enlarged tonsils with exudates and petechiae of the palate.

                                                                                                                                                                                        B. Group C Streptococcus presents with a red pharynx and enlarged tonsils with a yellow, blood tinged exudates
                                                                                                                                                                                        D. Neisseria gonorrhea of the pharynx may be asymptomatic

                                                                                                                                                                                        Coxsackievirus is covered as part of the NCCPA Dermatology Content Blueprint which accounts for 5% of your exam.

                                                                                                                                                                                        9. Which of the following is the most appropriate management of acute psychosis in a patient with schizophrenia?

                                                                                                                                                                                        A. Amitriptyline (Elavil)

                                                                                                                                                                                        B. Risperidone (Risperdal)
                                                                                                                                                                                        C. Lithium (Eskalith)
                                                                                                                                                                                        D. Sertraline (Zoloft)

                                                                                                                                                                                        Click here to see the answer

                                                                                                                                                                                        Answer: B. Risperidone (Risperdal)

                                                                                                                                                                                        There are numerous options used in the management of acute psychosis including benzodiazepines and antipsychotics such as haloperidol (first generation – typical -antipsychotic), risperidone or aripiprazole (second Generation – atypical – antipsychotics). Antidepressants and lithium have no benefit in the treatment of acute psychosis.

                                                                                                                                                                                        Schizophrenia is covered as part of the NCCPA psychiatry Content Blueprint which accounts for 6% of your exam.

                                                                                                                                                                                        10. A 25-year-old presents with pain in the proximal ulna after falling directly on the forearm. X-ray shows a fracture of the proximal 1/3rd of the ulna. There is an associated anterior radial head dislocation. What is the proper name for this condition?

                                                                                                                                                                                        A. Galeazzi fracture

                                                                                                                                                                                        B. Monteggia fracture
                                                                                                                                                                                        C. Colles’ fracture
                                                                                                                                                                                        D. Smith fracture

                                                                                                                                                                                        Click here to see the answer

                                                                                                                                                                                        Answer: B. Monteggia fracture

                                                                                                                                                                                        A Monteggia fracture is a fracture of the proximal ulna with anterior dislocation of the radial head.

                                                                                                                                                                                        A. A Galeazzi fracture is a fracture along the length of the radius with an injury to the distal radioulnar joint.

                                                                                                                                                                                        C. A Colles’ fracture is a fracture of the distal radius with dorsal displacement of the radial head.
                                                                                                                                                                                        D. A Smith fracture is a fracture of the distal radius with a ventral displacement of the radial head.

                                                                                                                                                                                        Monteggia fracture is covered as part of the NCCPA Musculoskeletal Content Blueprint which accounts for 10% of your exam.

                                                                                                                                                                                        Looking for all the podcast episodes?

                                                                                                                                                                                        This FREE series is limited to every other episode, you can download and enjoy the complete audio series by joining The PANCE and PANRE Exam Academy + SMARTYPANCE

                                                                                                                                                                                        I will be releasing new episodes every few weeks. The Academy is discounted, so sign up now.

                                                                                                                                                                                        Resources and Links From The Show
                                                                                                                                                                                        • My list of recommended PANCE and PANRE review books
                                                                                                                                                                                        • Download the FREE PANCE and PANRE Blueprint Checklist
                                                                                                                                                                                        • Get 20% of any Picmonic membership by using this link
                                                                                                                                                                                        • Sign up for the FREE daily PANCE and PANRE email series
                                                                                                                                                                                        • Join the Smarty PANCE NCCPA Content Blueprint Website + The PA Life Academy
                                                                                                                                                                                        • Members can take Emergency medicine EOR 1 (200 questions) and Emergency Medicine EOR 2 (184 questions)
                                                                                                                                                                                        • USE CODE “PALIFE” TO GET 10% OFF THE RUTGERS PANCE AND PANRE REVIEW COURSE
                                                                                                                                                                                        • This Podcast is also available on iTunes and Stitcher Radio for Android
                                                                                                                                                                                          1. iTunes: The Audio PANCE AND PANRE Podcast iTunes
                                                                                                                                                                                          2. Stitcher Radio: The Audio PANCE and PANRE Podcast Stitcher
                                                                                                                                                                                          3. Download The Content Blueprint Checklist

                                                                                                                                                                                            Follow this link to download your FREE copy of the Content Blueprint Checklist

                                                                                                                                                                                            Print it up and start crossing out the topics you understand, marking the ones you don’t and making notes of key terms you should remember. The PDF version is interactive and linked directly to the individual lessons on SMARTY PANCE.

                                                                                                                                                                                            Download

                                                                                                                                                                                            19 min

                                                                                                                                                                                          About The Audio PANCE and PANRE Physician Assistant Board Review Podcast

                                                                                                                                                                                          From the publisher's feed

                                                                                                                                                                                          Multiple Choice Physician Assistant Board Review and Rotation Exam Questions on the Go – Listen and Learn

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