The Audio PANCE and PANRE Physician Assistant Board Review Podcast

The Audio PANCE and PANRE Physician Assistant Board Review Podcast

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The Audio PANCE and PANRE Physician Assistant Board Review Podcast episodes

  • Episode 57: Endocrinology – The Audio PANCE/PANRE Board Review Podcast – Content Blueprint Review Endocrinology

    The Audio PANCE/PANRE PA Board Review Podcast

    Welcome to episode 57 of the FREE Audio PANCE and PANRE Physician Assistant Board Review Podcast.

    Join me as I cover ten PANCE and PANRE Board review questions from the SMARTYPANCE course content following the NCCPA™ content blueprint (download the FREE cheat sheet).

    This week we will be covering ten endocrinology board review questions based on the NCCPA PANCE and PANRE Content Blueprint. 

    Below you will find an interactive exam to complement the podcast.

    I hope you enjoy this free audio component to the examination portion of this site. The full board review includes over 2,000 interactive board review questions and is available to all members of the PANCE and PANRE Academy and SMARTYPANCE which are now bundled together into one very low price.

    • You can download and listen to past FREE episodes here, on iTunes, on Google Play Music or Stitcher Radio.
    • You can listen to the latest episode, take an interactive quiz and download your results below.
    • Listen Carefully Then Take The Practice Exam

      If you can’t see the audio player click here to listen to the full episode.

      Episode 57 – Endocrinology PANCE/PANRE Podcast Quiz

      The following 10 questions are linked to NCCPA Content Blueprint lessons from the SMARTYPANCE and PANRE Board review website. If you are a member you will be able to log in and view this interactive video content.

      1. A 53-year-old Hispanic woman comes to your clinic for her annual physical exam. She is obese, does not exercise, and regularly eats fried foods. A random blood glucose is 249 mg/dL. Her hemoglobin A1C is 9.5. Which of the following treatments would be weight neutral or cause weight loss in this patient?

      A. Glargine

      B. Glyburide
      C. Actos
      D. Metformin
      E. Glipizide

      Diabetes Mellitus Type 2 is covered as part of the NCCPA Endocrinology Content Blueprint which accounts for 6% of your exam.

      Click here to see the answer

      Answer: D. Metformin

      The patient in this vignette most likely has type II diabetes. Of the given treatments, only metformin is weight neutral in the majority of cases (i.e. it does not cause significant weight gain/loss). Metformin is a first-line treatment for type II DM in most patients. Although the exact mechanism is unknown, it appears to decrease gluconeogenesis and increase insulin sensitivity. There is no risk of hypoglycemia or weight gain (though some patients even lose weight). The most high yield side effect involves lactic acidosis, particularly in patients with renal insufficiency. 

      A. Glargine, a long-acting insulin, can cause weight gain.

      B. Glyburide, a second-generation sulfonylurea, can cause weight gain.
      C. Actos, a thiazolidinedione, can cause weight gain.
      E. Glipizide, a second-generation sulfonylurea, can cause weight gain.

      2. A solitary thyroid nodule is noted on physical examination. The TSH level is normal. The next step in the evaluation is:

      A. measurement of T4 and free T3 levels.

      B. a radionuclide thyroid scan.
      C. a fine needle biopsy.
      D. a surgical excision.

      Solitary thyroid nodule is covered as part of thyroid neoplastic disease in the NCCPA Endocrinology Content Blueprint which accounts for 6% of your exam.

      Click here to see the answer

      Answer: C. a fine needle biopsy

      Fine needle aspiration (FNA) is the first step in the evaluation of a solitary nodule with a normal TSH level. FNA has a high level of accuracy in diagnosing benign versus malignant nodules in this setting.

      A. Measurement of T4 and T3 levels would not be of benefit in the evaluation of a solitary thyroid nodule with a normal TSH level.

      B. A thyroid scan would be the next step if there were a low TSH level.
      D. Surgical excision would be the final step after determination of malignancy or suspicion of malignancy by FNA.

      3. An 18-year-old male with a past medical history of type I diabetes presents to the emergency room with polyuria, polydipsia, and dehydration. Vital signs reveal tachycardia and hypotension. The physical exam is significant for dry mucous membranes and decreased skin turgor. In the waiting room, he begins vomiting and complains of intense abdominal pain. You observe him taking rapid, deep breaths, and over the course of his brief stay, getting more somnolent. Which of the following abnormalities would be expected in this patient?

      A. Hypernatremia

      B. Decreased total body potassium
      C. Hypoglycemia
      D. Absence of urinary beta-OH-butyrate
      E. Non-anion-gap metabolic acidosis

      Diabetic ketoacidosis is covered under Diabetes Mellitus Type 1 as part of the NCCPA Endocrinology Content Blueprint which accounts for 6% of your exam.

      Click here to see the answer

      Answer: B. Decreased total body potassium

      This type I diabetic is presenting with signs and symptoms of diabetic ketoacidosis (DKA). In DKA, total body potassium stores are generally decreased due to osmotic diuresis. DKA is a life-threatening emergency that may occur in either type I or type II diabetics but is significantly more common in patients with type I. The pathogenesis is related to insulin deficiency resulting in hyperglycemia that leads to osmotic diuresis and hypovolemia. The inability of the body to use the available glucose for ATP production results in ketone formation and eventually an anion gap metabolic acidosis. Serum potassium levels may be low, normal, or elevated, but total body stores are generally low and require repletion. Common precipitating factors include infection, trauma, myocardial infarction, sepsis and, of course, inadequate insulin administration. Patients may present with nausea, vomiting, abdominal pain, Kussmaul respirations (rapid, deep breaths), dehydration, polydipsia, polyuria and may eventually progress to altered mental status.

      A. Patients with DKA more often present with hyponatremia. Remember that serum sodium decreases 1.6 mEq/L for every 100 mg/dL increase in glucose.

      C. DKA requires hyperglycemia by definition. Hypoglycemia can be a complication of treatment if glucose is not monitored closely.
      D. Ketones, such as Beta-OH-Butyrate, are commonly found in patients with DKA since ketogenesis is a normal response to starvation caused by the inadequate transit of serum glucose into cells.
      E. Patients with DKA present with an anion-gap metabolic acidosis secondary to ketoacids.

      4. A 30-year-old female complains of fatigue, weakness, diminished appetite, weight loss, and syncope. She denies fever, chest or abdominal pain, palpitations, changes in bowel patterns or sleep patterns. Physical examination reveals a thin female, BP 90/65 mmHg, and pulse 80 beats per minute. Pulmonary, cardiovascular, abdominal, and neurologic exam are without abnormalities. Areas of brown and bronze hyperpigmentation are noted on her elbows and the creases of her hands. Which of the following is the most likely diagnosis?

      A. Addison’s disease

      B. Cushing’s disease
      C. Anorexia nervosa
      D. Porphyria

      This condition is covered as part of the NCCPA Endocrinology Content Blueprint and accounts for 6% of the exam

      Click here to see the answer

      Answer: A. Addison’s disease

      Addison’s disease (adrenal insufficiency) would account for all her symptoms, the hypotension, and the hyperpigmentation of the skin.

      B. Cushing’s disease, the presence of an ACTH-producing adenoma, is characterized by central obesity, hypertension, moon facies, purple striae, and glucose intolerance.

      C. Anorexia nervosa may explain the weakness, weight loss, hypotension, and syncope, however, a normal pulse rate would be an unexpected finding along with the hyperpigmentation.
      D. Porphyria presents acutely with anxiety, depression, disorientation, and insomnia.

      5. A 39-year-old male presents to your clinic complaining of increasing constant headaches and progressive loss of peripheral vision. His medical and family history is unremarkable. Physical examination reveals bitemporal hemianopsia but is otherwise without any abnormalities. Which of the following is the most likely diagnosis?

      Answers

      A. An aneurysm involving the circle of Willis

      B. A migraine headache
      C. Multiple sclerosis
      D. Pituitary tumor

      This condition is covered as part of the NCCPA Endocrinology Content Blueprint and accounts for 6% of the exam

      Click here to see the answer

      Answer: D. A pituitary tumor 

      A pituitary tumor would account for the headaches and the loss of the peripheral vision in both visual fields. As the tumor grows, the optic chiasm will be compressed by the tumor.

      A. An aneurysm involving the circle of Willis would result in CN III palsy. This would be a rare finding.

      B. Although a migraine headache may produce visual field defects, these defects would remit upon resolution of the migraine. It would also be unusual to have the scotomas occur bilaterally.
      C. Optic neuritis associated with multiple sclerosis presents with decreased visual acuity, dimness, or color desaturation in the central visual field. It would not affect the periphery.

      6. Radioactive iodine is most successful in treating hyperthyroidism that results from

      A. Grave’s disease.

      B. subacute thyroiditis.
      C. Hashimoto’s thyroiditis.
      D. papillary thyroid carcinoma.

      Watch this ReelDx Video of a 16-year-old with ADHD presents with chest pain and exophthalmos

      Diseases of the thyroid gland are covered as part of the NCCPA Endocrinology Content Blueprint and accounts for 6% of the exam

      Click here to see the answer

      Answer:  A. Grave’s disease.

      Radioactive iodine is an excellent method to destroy overactive thyroid tissue of Grave’s disease.

      B. Radioactive iodine is ineffective in subacute thyroiditis due to the thyroid’s low uptake of iodine.

      C. Radioiodine uptake is low in Hashimoto’s thyroiditis and is often transient.
      D. Papillary thyroid carcinoma is a common thyroid malignancy and must be treated by a thyroidectomy.

      7. A newborn infant exhibits prolonged jaundice, feeding problems, hypotonia, and an enlarged tongue. Proper treatment in this infant would consist of which of the following?

      A. IV antibiotics

      B. Thyroid hormone replacement
      C. Hepatitis B immunoglobulin
      D. Vitamin B6 supplement

      This condition is covered as part of the NCCPA Endocrinology Content Blueprint and accounts for 6% of the exam

      Click here to see the answer

      Answer: B. Thyroid hormone replacement 

      This scenario is consistent with congenital hypothyroidism. Measurement of TSH or T4 would confirm this and T4 should be given.

      C. Hepatitis and sepsis may account for the presence of jaundice, feeding problems, and hypotonia, but would not result in an enlarged tongue.

      D. A deficiency in vitamin B6 may lead to glossitis but would not account for or any of the other signs.

      8. Which of the following glucose-lowering agents act by delaying glucose absorption?

      A. Metformin (Glucophage)

      B. Acarbose (Precose)
      C. Glipizide (Glucotrol)
      D. Pioglitazone (Actos)

      Diabetes Mellitus Type 2 and associated medications are covered as part of the NCCPA Endocrinology Content Blueprint which accounts for 6% of your exam.

      Click here to see the answer

      Answer: B. Acarbose (Precose)

      Alpha-glucosidase inhibitors, such as acarbose, reduce glucose by delaying glucose absorption.

      A. Metformin, a biguanide, lowers glucose by decreasing hepatic glucose production and increased glucose utilization.

      C. Glipizide and other sulfonylureas work by increasing insulin secretion.
      D. Pioglitazone is a thiazolidinedione and decreases insulin resistance and increases glucose utilization.c

      9. Which of the following conditions may result in hypokalemia?

      A. Adrenal adenoma

      B. Hypoparathyroidism
      C. Hyperthyroidism
      D. Adrenal insufficiency

      Diseases of the Adrenal Glands are covered as part of the NCCPA Endocrinology Content Blueprint which accounts for 6% of your exam.

      Click here to see the answer

      Answer: A. Adrenal adenoma

      Excessive secretion of aldosterone from an adrenal adenoma will lead to sodium retention and the secretion of potassium in the distal tubule of the kidney, eventually leading to hypokalemia.

      B. Hypoparathyroidism and hyperthyroidism should not have any effect on potassium levels.

      D. Adrenal insufficiency would lead to hyperkalemia.

      10. A 7-year-old child with a history of type 1 diabetes mellitus for 3 years presents for routine follow-up. The mother states that the child has been having nightmares and night sweats. Additionally, his average morning glucose readings have risen from an average of 100 mg/dL to 145 mg/dL over the past week. This child is most likely experiencing

      A. a growth spurt.

      B. emotional problems.
      C. the Somogyi effect.
      D. the dawn phenomenon.

      The Somogyi effect and the dawn phenomenon are covered under Diabetes Mellitus Type 1 as part of the NCCPA Endocrinology Content Blueprint which accounts for 6% of your exam.

      Click here to see the answer

      Answer: C. the Somogyi effect.

      This refers to nocturnal hypoglycemia, which stimulates counter-regulatory hormone release resulting in rebound hyperglycemia.

      A. Nightmares and night sweats are not associated with growth spurts.

      B. With this limited history, it is impossible to label the child as emotionally unstable.
      D. This refers to an early morning rise in plasma glucose due to reduced tissue sensitivity to insulin between 5 AM and 8 AM. It is not associated with nightmares and night sweats.

      Looking for all the podcast episodes?

      This FREE series is limited to every other episode, you can download and enjoy the complete audio series by joining The PANCE and PANRE Exam Academy + SMARTYPANCE

      I will be releasing new episodes every few weeks. The Academy is discounted, so sign up now.

      Resources and Links From The Show
      • My list of recommended PANCE and PANRE review books
      • Download the FREE PANCE and PANRE Blueprint Checklist
      • Sign up for the FREE daily PANCE and PANRE email series
      • Join the Smarty PANCE NCCPA Content Blueprint Website + The PA Life Academy
      • View Tetrology of Fallot Picmonic: Use Code “SMARTYPANCE” to get 20% OFF any year-long Picmonic Membership
      • USE CODE “PALIFE” TO GET 10% OFF THE RUTGERS PANCE AND PANRE REVIEW COURSE
      • This Podcast is also available on iTunes and Stitcher Radio for Android
        1. iTunes: The Audio PANCE AND PANRE Podcast iTunes
        2. Stitcher Radio: The Audio PANCE and PANRE Podcast Stitcher
        3. Download The Content Blueprint Checklist

          Follow this link to download your FREE copy of the Content Blueprint Checklist

          Print it up and start crossing out the topics you understand, marking the ones you don’t and making notes of key terms you should remember. The PDF version is interactive and linked directly to the individual lessons on SMARTY PANCE.

          Download

          18 min
        4. Episode 55: The Audio PANCE and PANRE Board Review Podcast – Mixed Content Blueprint Review

          Welcome to episode 55 of the FREE Audio PANCE and PANRE Physician Assistant Board Review Podcast.

          Join me as I cover ten PANCE and PANRE Board review questions from the SMARTYPANCE course content following the NCCPA™ content blueprint (download the FREE cheat sheet).

          This week we will be covering ten general board review questions based on the NCCPA PANCE and PANRE Content Blueprint. 

          Below you will find an interactive exam to complement the podcast.

          I hope you enjoy this free audio component to the examination portion of this site. The full board review includes over 2,000 interactive board review questions and is available to all members of the PANCE and PANRE Academy and SMARTYPANCE which are now bundled together into one very low price.

          • You can download and listen to past FREE episodes here, on iTunes, on Google Play Music or Stitcher Radio.
          • You can listen to the latest episode, take an interactive quiz and download your results below.
          • Listen Carefully Then Take The Quiz

            If you can’t see the audio player click here to listen to the full episode.

            Episode 55 PANCE and PANRE Podcast Quiz

            The following 10 questions are linked to NCCPA Content Blueprint lessons from the SMARTYPANCE and PANRE Board review website. If you are a member you will be able to log in and view this interactive video content.

            1. Which of the following physical examination findings would be consistent with a pleural effusion?

            A. Hyperresonance to percussion

            B. Increased tactile fremitus
            C. Unilateral lag on chest expansion
            D. Egophony

            Pleural effusions are covered as part of the NCCPA Content Blueprint Pulmonology section which accounts for 10% of the exam

            View this ReelDx patient video case of a 68-year-old female complaining of bilateral chest pain and difficulty breathing. Included in this lesson is the Picmonic explaning Light’s Criteria.

            Click here to see the answer

            Answer: C. Unilateral lag on chest expansion

            A lag on chest expansion may be seen in the presence of a pleural effusion.

            A. Hyperresonance to percussion would be suggestive of emphysema or pneumothorax.

            B. Increased tactile fremitus would be consistent with a consolidation.
            D. The presence of egophony would be consistent with a consolidation.

            2. A 55 year-old female presents with complaints of stiffness, aching, and pain in the muscles of her neck, shoulders, lower back, hips, and thighs. There is no associated weakness associated with the stiffness and achiness. Laboratory evaluation shows an elevated C reactive protein and erythrocyte sedimentation rate. Which of the following medications is used to treat this condition immediately and will also serve to prevent a known complication from this disorder?

            A. Glucocorticoids

            B. Cyclophosphamide (Cytoxan)
            C. Methotrexate (Rheumatrex)
            D. Azathioprine (Imuran)

            This condition is covered as part of the NCCPA Musculoskeletal Content Blueprint and accounts for 10% of the exam

            Click here to see the answer

            Answer: A. Glucocorticoids

            This patient has polymyalgia rheumatica and treatment with glucocorticoids can relieve discomfort and prevent the associated ischemic temporal arteritis, which threatens vision.

            B. Cyclophosphamide is an immunosuppressant used in the treatment of acute leukemia.

            C. Methotrexate is a folate inhibitor used to treat rheumatoid arthritis, not polymyalgia rheumatica.
            D. Azathioprine is an immunosuppressant that is used to treat rheumatic disease and inflammatory bowel disease, not polymyalgia rheumatica.

            3. A 35 year-old pregnant patient presents with fever, chills, and left-sided flank pain. On physical examination left-sided CVA tenderness is noted. Urinalysis reveals numerous white blood cells and white blood cell casts. Which of the following is the most appropriate treatment?

            A. Oral ciprofloxacin (Cipro)

            B. Oral trimethoprim-sulfamethoxazole (Bactrim)
            C. IV gentamicin (Garamycin)
            D. IV ceftriaxone (Rocephin)

            This condition is covered as part of the NCCPA Genitourinary Content Blueprint and accounts for 6% of the exam

            Click here to see the answer

            Answer: D. IV ceftriaxone (Rocephin)

            IV cephalosporins are first line treatment of pyelonephritis in a pregnant patient, followed by oral step-down therapy.

            A. See B for explanation.

            B. The fluoroquinolones and trimethoprim-sulfamethoxazole are contraindicated in pregnancy.
            C. Gentamicin is not indicated as first line therapy in the treatment of pyelonephritis in a pregnant patient.

            4. A 26 year-old female arrives in the emergency department with friends who say she was standing in front of her church, dressed in a white bathrobe, claiming to be the Virgin Mary and handing out $100 bills to all passers-by. Her friends noted that she had been depressed lately, but now seems completely euphoric. She had a similar episode two years ago. Which of the following is the most appropriate treatment?

            A. Inpatient olanzapine (Zyprexa) therapy

            B. Inpatient electroconvulsive therapy
            C. Outpatient paroxetine (Paxil) therapy
            D. Outpatient psychotherapy

            This condition is covered as part of the NCCPA Psychiatry Content Blueprint and accounts for 6% of the exam

            Click here to see the answer

            Answer: A. Inpatient olanzapine (Zyprexa) therapy

            Treatment of the manic phase is usually done in the hospital to protect patients from behaviors associated with grandiosity (spending inordinate amounts of money, making embarrassing speeches, etc.). Lithium, valproate, and olanzapine are considered effective in the manic stage; the depressive stage is treated with

            antidepressants.

            5. A 19 year-old patient was involved in a motor vehicle crash and brought to the emergency department fully immobilized. The patient sustained multiple blunt injuries to the chest and abdomen. During the trauma assessment, there was no blood at the urethral meatus and a Foley catheter was placed. The urine was positive for blood on the dipstick. Which of the following is the most appropriate diagnostic test

            A. Retrograde urethrography

            B. CT scan of abdomen and pelvis
            C. Serum haptoglobin
            D. Urine myoglobin

            Click here to see the answer

            Answer: B. CT scan of abdomen and pelvis

            CT scan of the abdomen and pelvis is indicated in blunt trauma including those resulting in hematuria or when renal injury is suspected.

            A. A retrograde urethrogram should be performed when blood is found at the external urinary meatus prior to insertion of a catheter.

            C. A decreased serum haptoglobin is seen in hemolysis and does not provide information on renal status.
            D. A positive test for blood in the absence of red blood cells on urine examination suggests myoglobinuria, and should be confirmed by electrophoresis.

            6. A 48 year-old male presents with complaints of heartburn that occurs approximately 45 minutes after eating about three times a week that is relieved by antacids. He claims to have followed advice about elevating the head of the bed, avoiding spicy foods, and losing weight, but continues to have heartburn. Which of the following is the most appropriate next step?

            A. Ranitidine (Zantac)

            B. Sucralfate (Carafate)
            C. Metoclopramide (Reglan)
            D. Misoprostol (Cytotec)

            GERD (Gastroesophageal reflux disease) is covered as part of the NCCPA GI and Nutrition Content Blueprint and accounts for 10% of the exam

            Click here to see the answer

            Answer: A. Ranitidine (Zantac)

            Ranitidine, an H2 receptor blocker, is indicated for the treatment of mild, intermittent symptoms of gastroesophageal reflux disease.

            B. Sucralfate is used in the treatment of duodenal ulcers.

            C. Metoclopramide is indicated for the treatment of gastroparesis as a first-line agent and as a second-line agent in the treatment of refractory gastroesophageal reflux.
            D. Misoprostol is indicated for the prevention of NSAID-induced gastritis.

            7. Radioactive iodine (I131) is most successful in treating hyperthyroidism that results from

            A. Grave’s disease.

            B. subacute thyroiditis.
            C. Hashimoto’s thyroiditis.
            D. papillary thyroid carcinoma.

            Watch this ReelDx Video of a 16-year-old with ADHD presents with chest pain and exophthalmos

            Diseases of the thyroid gland are covered as part of the NCCPA Endocrinology Content Blueprint and accounts for 6% of the exam

            Click here to see the answer

            Answer: A. Grave’s disease.

            Radioactive iodine (I131) is an excellent method to destroy overactive thyroid tissue of Grave’s disease.

            B. Radioactive iodine is ineffective in subacute thyroiditis due to the thyroid’s low uptake of iodine.

            C. Radioiodine uptake is low in Hashimoto’s thyroiditis making radioactive therapy ineffective.
            D. Papillary thyroid carcinoma is a common thyroid malignancy and should be treated by a thyroidectomy.

            8. An 8 year-old boy is brought to a health care provider complaining of dyspnea and fatigue. On physical examination, a continuous machinery murmur is heard best in the second left intercostal space and is widely transmitted over the precordium. The most likely diagnosis is

            A. ventricular septal defect

            B. atrial septal defect
            C. congenital aortic stenosis
            D. patent ductus arteriosus

            This disorder is covered as part of the NCCPA Cardiology Content Blueprint and accounts for 9% of the exam

            Click here to see the answer

            Answer: D. patent ductus arteriosus.

            Patent ductus arteriosus is classically described in children as a continuous machinery-type murmur that is widely transmitted across the precordium.

            A. Ventricular septal defect causes a holosystolic murmur rather than a continuous machinery-like murmur.

            B. Atrial septal defect causes a fixed split S2 rather than a continuous systolic heart murmur.
            C. Congenital aortic stenosis causes a crescendo-decrescendo systolic murmur heard best in the second intercostal space.

            9. A 63 year-old male with history of hypertension and tobacco abuse presents complaining of dyspnea on exertion for two weeks. The patient admits to one episode of chest discomfort while shoveling snow which was relieved after five minutes of rest. Vital signs are BP 130/70, HR 68, RR 14. Heart exam reveals regular rate and rhythm, normal S1 and S2, no murmur, gallop, or rub. Lungs are clear to auscultation bilaterally. There is no edema noted. Which of the following is the most appropriate initial diagnostic study for this patient?

            A. Helical CT scan

            B. Chest x-ray
            C. Nuclear stress test
            D. Cardiac catheterization

            Angina is covered as part of the NCCPA Cardiology Content Blueprint which accounts for 10% of the exam

            Click here to see the answer

            Answer: C. Nuclear stress test

            In patients with classic symptoms of angina, nuclear stress testing is the most widely used test for diagnosis of ischemic heart disease.

            A. Helical CT scan aids in the diagnosis of pulmonary embolism, not in the evaluation of angina.

            B. Chest x-ray is not used as a diagnostic study to evaluate symptoms of angina or coronary heart disease.
            D. Coronary angiography is indicated in patients with classic stable angina who are severely symptomatic despite medical therapy and are being considered for percutaneous intervention (PCI), patients with troublesome symptoms that are difficult to diagnose, angina symptoms in a patient who has survived sudden cardiac death event, patients with ischemia on noninvasive testings.

            10. A 52 year-old male with history of hypertension and hyperlipidemia presents with an acute myocardial infarction. Urgent cardiac catheterization is performed and shows a 90% occlusion of the left anterior descending artery. The other arteries have minimal disease. Ejection fraction is 45%. Which of the following is the treatment of choice in this patient?

            A. Coronary artery bypass grafting (CABG)

            B. Streptokinase
            C. Percutaneous coronary intervention (PCI)
            D. Warfarin (Coumadin)

            Acute myocardial infarction [Non-ST-segment elevation (NSTEMI)] and [ST-segment elevation myocardial infarction (STEMI)] are covered as part of the NCCPA Cardiology Content Blueprint which represents 16% of your exam

            Click here to see the answer

            Answer: C. Percutaneous coronary intervention (PCI)

            Immediate coronary angiography and primary percutaneous coronary intervention have been shown to be superior to thrombolysis.

            A. Percutaneous coronary intervention is a better, less invasive alternative to CABG for single vessel coronary artery disease.

            B. Streptokinase is not commonly used for the treatment of acute myocardial infarction because it is ineffective at opening the occluded artery and reducing mortality. Streptokinase would be harmful because it would increase the risk of bleeding.
            D. Warfarin is used to prevent thrombosis and not for acute treatment.

            Looking for all the podcast episodes?

            This FREE series is limited to every other episode, you can download and enjoy the complete audio series by joining The PANCE and PANRE Exam Academy + SMARTYPANCE

            I will be releasing new episodes every few weeks. The Academy is discounted, so sign up now.

            Resources and Links From The Show
            • My list of recommended PANCE and PANRE review books
            • Download the FREE PANCE and PANRE Blueprint Checklist
            • Sign up for the FREE daily PANCE and PANRE email series
            • Join the Smarty PANCE NCCPA Content Blueprint Website + The PA Life Academy
            • View Tetrology of Fallot Picmonic: Use Code “SMARTYPANCE” to get 20% OFF any year-long Picmonic Membership
            • USE CODE “PALIFE” TO GET 10% OFF THE RUTGERS PANCE AND PANRE REVIEW COURSE
            • This Podcast is also available on iTunes and Stitcher Radio for Android
              1. iTunes: The Audio PANCE AND PANRE Podcast iTunes
              2. Stitcher Radio: The Audio PANCE and PANRE Podcast Stitcher
              3. Download The Content Blueprint Checklist

                Follow this link to download your FREE copy of the Content Blueprint Checklist

                Print it up and start crossing out the topics you understand, marking the ones you don’t and making notes of key terms you should remember. The PDF version is interactive and linked directly to the individual lessons on SMARTY PANCE.

                Download

                20 min
              4. Episode 53: General Surgery End of Rotation Exam – The Audio PANCE and PANRE Podcast

                Welcome to episode 53 of the FREE Audio PANCE and PANRE Physician Assistant Board Review Podcast.

                Join me as I cover ten PANCE and PANRE Board review questions from the Academy course content following the NCCPA™ content blueprint (download the FREE cheat sheet) and the PAEA End of Rotation™ Exams Blueprints & Topic Lists.

                This week we will be covering ten General Surgery End of Rotation Exam Questions that are now part of the SMARTYPANCE website. 

                Below you will find an interactive exam to complement the podcast.

                I hope you enjoy this free audio component to the examination portion of this site. The full board review includes over 2,000 interactive board review questions and is available to all members of the PANCE and PANRE Academy and SMARTYPANCE which are now bundled together into one very low price.

                • You can download and listen to past FREE episodes here, on iTunes, on Google Play Music or Stitcher Radio.
                • You can listen to the latest episode, take an interactive quiz and download your results below.
                • Listen Carefully Then Take The Quiz

                  If you can’t see the audio player click here to listen to the full episode.

                  Episode 51: General Surgery Endo of Rotation Exam Podcast Quiz

                  The following 10 questions are linked to NCCPA™ Content Blueprint lessons from the SMARTYPANCE and PANRE Board review website. If you are a member you will be able to log in and view this interactive video content.

                  1. An 18-year-old patient has a tibia/fibula fracture following a motorcycle crash. Twelve hours later the patient presents with increased pain despite adequate doses of analgesics and immobilization. Which of the following is the most likely diagnosis?

                  A. avascular necrosis

                  B. myositis ossificans
                  C. compartment syndrome
                  D. reflex sympathetic dystrophy

                  Click here to see the answer

                  Answer: C. Compartment syndrome

                  Compartment syndrome is characterized by a pathological increase of pressure within a closed space and results from edema or bleeding within the compartment. It may occur as an early local complication of fracture.

                  A. Avascular necrosis occurs primarily in muscles post-traumatically and may not arise for several months after an injury.

                  B. Myositis ossificans is a late complication of fracture resulting from disruption of the blood supply to the bone.

                  D. Reflex sympathetic dystrophy is characterized by painful wasting of the hand muscles that may be secondary to injury and could occur as a late complication.

                  2. A 25-year-old male presents to the ED with left calf pain and cramping, as well as nausea and vomiting. He admits to “partying with cocaine all night”. He describes his urine as a dark brown color. Serum creatinine kinase (CK) is 1325 IU/L (Normal Range 32-267 IU/L). Which of the following is the initial mainstay of therapy for this condition?

                  A. IV rehydration

                  B. Fasciotomy
                  C. Toradol (Ketorolac)
                  D. Hydrotherapy

                  Click here to see the answer

                  Answer: A. IV rehydration

                  IV rehydration with crystalloids for 24 to 72 hours is the mainstay of therapy for rhabdomyolysis.

                  B. Fasciotomy is indicated for compartment syndrome.

                  C. NSAIDs, such as Toradol (Ketorolac), should not be used due to the vasoconstrictive effects on the kidneys.

                  D. Hydrotherapy is not useful or indicated for Rhabdomyolysis

                  3. A 42-year-old male presents complaining of a sudden onset of a severe intermittent pain originating in the flank and radiating into the right testicle. He also complains of nausea and vomiting. On examination, the patient is afebrile but restless. Examination of the abdomen reveals tenderness to palpation along the right flank with no rebound or direct testicular tenderness. Urinalysis reveals a pH of 5.4 and microscopic hematuria but is otherwise unremarkable. Which of the following is the most likely diagnosis?

                  A. Bladder cancer

                  B. Nephrolithiasis
                  C. Acute appendicitis
                  D. Acute epididymitis

                  Click here to see the answer

                  Answer: B. Nephrolithiasis

                  A sudden onset of severe colicky flank pain associated with nausea and vomiting as well as the absence of rebound or direct testicular tenderness makes nephrolithiasis the most likely diagnosis. This is further supported by the presence of hematuria on the urinalysis.

                  A. While bladder cancer may have associated microscopic hematuria, it presents with painless hematuria or irritative voiding symptoms.

                  C. While an acute abdomen, such as acute appendicitis, is in the differential diagnosis, the absence of fever and peritoneal signs makes this diagnosis less likely

                  D. The absence of fever, as well as non-tenderness to palpation of the testes, suggests a renal rather than gonadal cause of the patient’s symptoms

                  4. What is the term for blue discoloration about the umbilicus?

                  A. Cullen’s sign

                  B. Murphy’s sign
                  C. Rovsing’s sign
                  D. Turner sign

                  Click here to see the answer

                  Answer: A. Cullen’s sign

                  Cullen’s sign is a blue discoloration about the umbilicus and can occur in hemorrhagic pancreatitis and results from hemoperitoneum.

                  B. Murphy’s sign is seen in liver and gallbladder disease by which the patient abruptly halts deep inspiration due to pain in the right upper quadrant while the examiner’s hand is keeping stable pressure to the area.

                  C. Rovsing’s sign is positive when the patient experiences right-sided abdominal pain with palpation to the left side. This is generally seen in those with appendicitis.

                  D. Turner sign is also seen in severe, acute pancreatitis but is represented by a green-brown discoloration of bilateral flanks

                  5. A 25-year-old female presents with right lower quadrant pain, right flank pain, nausea, and vomiting. Her temperature is 39.6 degrees C. There is right CVA tenderness and RLQ tenderness. The pelvic exam is unremarkable. Urinalysis reveals pH 7.0, trace protein, negative glucose, negative ketones, positive blood, and positive nitrates. Specific gravity is 1.022. Microscopy shows 102 RBCs/HPF, 50-75 WBCs/HPF, rare epithelial cells, and WBC casts. The most likely diagnosis is

                  A. acute salpingitis

                  B. nephrolithiasis
                  C. acute pyelonephritis
                  D. appendicitis

                  Click here to see the answer

                  Answer: C. acute pyelonephritis

                  Acute pyelonephritis presents with flank pain, fever, and generalized muscle tenderness. Urinalysis shows pyuria with leukocyte casts.

                  A. Acute salpingitis would be suggested if pelvic exam abnormalities were present.

                  B. Nephrolithiasis does not usually present with fever or casts. Urinalysis will have RBCs present.

                  D. This scenario is consistent with acute pyelonephritis, not acute appendicitis.

                  6. A 26-year-old gravida 0 sexually active female presents to the emergency room complaining of colicky pain in her lower abdomen for the past 12 hours. She passed out earlier in the day while trying to have a bowel movement. Her last menstrual period was 6 weeks ago. She has noted vaginal spotting over the last 24 hours. Vital signs show Temp 37 degrees C, BP 96/60mmHg, P 110, R 16, Oxygen Sat. 98%. Abdominal exam is positive for distension and tenderness. Bowel sounds are decreased. Pelvic exam shows cervical motion and adnexal tenderness. Which of the following is the most likely diagnosis?

                  A. Ectopic pregnancy 

                  B. Appendicitis 
                  C. Crohn’s disease 
                  D. Pelvic inflammatory disease

                  Click here to see the answer

                  Answer: A. Ectopic pregnancy 

                  High suspicion for ectopic pregnancy should be maintained when any possible pregnant woman presents with vaginal bleeding or abdominal pain.

                  B. Appendicitis presents with nausea, vomiting and periumbilical pain that moves to the right lower quadrant of the abdomen.

                  C. Crohn’s disease is more common in women and may present with an acute abdomen. However, the pelvic examination would be normal.

                  D. In pelvic inflammatory disease, the temperature is usually above 38 degrees C and pelvic pain usually follows onset of cessation of menses

                  7. A 12-year-old boy presents to the office with pain in his legs with activity gradually becoming worse over the past month. He is unable to ride a bicycle with his friends due to the pain in his legs. Examination of the heart reveals an ejection click and accentuation of the second heart sound. Femoral pulses are weak and delayed compared to the brachial pulses. Blood pressure obtained in both arms is elevated. Chest x-ray reveals rib notching. Which of the following is the most likely diagnosis?

                  A. abdominal aortic aneurysm

                  B. pheochromocytoma
                  C. coarctation of the aorta
                  D. thoracic outlet syndrome

                  Click here to see the answer

                  Answer: C. coarctation of the aorta

                  Coarctation is a discrete or long segment of narrowing adjacent to the left subclavian artery. As a result of the coarctation, systemic collaterals develop. X-ray findings occur from the dilated and pulsatile intercostal arteries and the “3” is due to the coarctation site with proximal and distal dilations.

                  A. Abdominal aortic aneurysm is usually asymptomatic until the patient has dissection or rupture. It is uncommon in a child.

                  B. Pheochromocytoma classically causes paroxysms of hypertension due to catecholamine release from the adrenal medulla but does not cause variations in blood pressure in the upper and lower extremities.

                  D. Thoracic outlet syndrome occurs when the brachial plexus, subclavian artery, or subclavian vein becomes compressed in the region of the thoracic outlet. It is the most common cause of acute arterial occlusion in the upper extremity of adults under 40 years old

                  8. A 28-year-old male presents with burns sustained from hot grease splashed on his left hand earlier this afternoon. The burn extends from his palm to the volar aspect of his wrist and has an erythematous base, covered by an intact blister. There are a few small scattered blisters over the dorsum of the left hand. Which of the following is the initial intervention of choice?

                  A. Tetanus prophylaxis 

                  B. Admission to a burn unit 
                  C. Intravenous fluid administration 
                  D. Debridement of blisters

                  Click here to see the answer

                  Answer: A. Tetanus prophylaxis

                  Tetanus prophylaxis should be initially considered in all burn patients. 

                  B. Admission to a burn unit is not indicated for adult patients with uncomplicated partial thickness burns covering less than 15 to 20% of total body surface area (TBSA).

                  C. IV fluids are indicated for severe partial thickness burns covering more than 10% TBSA or in burns with complications.

                  D. Debridement of blisters is controversial, however blisters on the palms and soles should remain intact.

                  9. Which of the following is the selected method for the prevention of venous thromboembolism in a 38-year-old male undergoing an inguinal hernia repair?

                  A. early ambulation

                  B. elastic stockings
                  C. intermittent pneumatic compression
                  D. low-molecular weight heparin

                  Click here to see the answer

                  Answer: A. early ambulation 

                  Early ambulation is recommended for prophylaxis of venous thromboembolism in low-risk, minor procedures when the patient is under 40 years of age and there are no clinical risk factors.

                  B. Elastic stockings are indicated for patients at moderate risk of venous thromboembolism in ages 40-60 with minor procedures with additional thrombosis risk factor, or major operations for patients under age 40 without additional clinical risk factors.

                  C. Intermittent pneumatic compression is indicated in patients undergoing a major operation plus an increased risk of bleeding.

                  D. Low molecular weight heparin is indicated in patients undergoing orthopedic surgery, neurosurgery, or trauma with an identifiable risk factor for thromboembolism.

                  10. A patient presents with abdominal pain in the right lower quadrant, examination reveals increased pain in the right lower quadrant on deep palpation of the left lower quadrant. This is commonly known as which of the following?

                  A. Psoas sign

                  B. Murphy’s sign
                  C. Rovsing’s sign
                  D. Obturator sign

                  Click here to see the answer

                  Answer: C. Rovsing’s sign 

                  A positive Rovsing’s sign can be elicited in a patient with appendicitis when increased pain occurs in the right lower quadrant upon palpation of the left lower quadrant. 

                  A. Psoas sign is right lower quadrant pain with right leg extension seen in acute appendicitis

                  B. Murphy’s sign is seen in liver and gallbladder disease in which the patient abruptly halts deep inspiration due to discomfort as the examiner’s hand applies pressure to the right upper quadrant.

                  D. Obturator sign is right lower quadrant pain with internal rotation of the hip seen in acute appendicitis

                  Appendicitis: RLQ pain, + Obturator and Psoas sign

                  Looking for all the podcast episodes?

                  This FREE series is limited to every other episode, you can download and enjoy the complete audio series by joining The PANCE and PANRE Exam Academy + SMARTYPANCE

                  I will be releasing new episodes every few weeks. The Academy is discounted, so sign up now.

                  Resources and Links From The Show
                  • Join the PANCE and PANRE Academy + Smarty PANCE
                  • My list of recommended PANCE and PANRE review books
                  • Download the FREE PANCE and PANRE Blueprint Checklist
                  • Sign up for the FREE daily PANCE and PANRE email series
                  • The Smarty PANCE NCCPA Content Blueprint Website + The PA Life Academy
                  • USE CODE “PALIFE” TO GET 10% OFF THE RUTGERS PANCE AND PANRE REVIEW COURSE
                  • This Podcast is also available on iTunes and Stitcher Radio for Android
                    1. iTunes: The Audio PANCE AND PANRE Podcast iTunes
                    2. Stitcher Radio: The Audio PANCE and PANRE Podcast Stitcher
                    3. Download The Content Blueprint Checklist

                      Follow this link to download your FREE copy of the Content Blueprint Checklist

                      Print it up and start crossing out the topics you understand, marking the ones you don’t and making notes of key terms you should remember. The PDF version is interactive and linked directly to the individual lessons on SMARTY PANCE.

                      FREE Download

                      20 min
                    4. Episode 51: The Audio PANCE and PANRE Board Review Podcast – Comprehensive Audio Quiz

                      Welcome to episode 51 of the FREE Audio PANCE and PANRE Physician Assistant Board Review Podcast.

                      Join me as I cover ten PANCE and PANRE Board review questions from the Academy course content following the NCCPA™ content blueprint (download the FREE cheat sheet).

                      This week we will be covering ten general board review questions based on the NCCPA PANCE and PANRE Content Blueprint. 

                      Below you will find an interactive exam to complement the podcast.

                      I hope you enjoy this free audio component to the examination portion of this site. The full board review includes over 2,000 interactive board review questions and is available to all members of the PANCE and PANRE Academy and SmartyPANCE which are now bundled together into one very low price.

                      • You can download and listen to past FREE episodes here, on iTunes, on Google Play Music or Stitcher Radio.
                      • You can listen to the latest episode, take an interactive quiz and download your results below.
                      • Listen Carefully Then Take The Quiz

                        If you can’t see the audio player click here to listen to the full episode.

                        Episode 51 PANCE and PANRE Podcast Quiz

                        The following 10 questions are linked to NCCPA Content Blueprint lessons from the SMARTYPANCE and PANRE Board review website. If you are a member you will be able to log in and view this interactive video content.

                        1. A 42-year-old male with a history of constipation presents with complaints of severe pain with defecation described as feeling like he is “tearing apart.” He has also noted occasional small amounts of blood on toilet paper. External examination of the rectum is unremarkable and an internal rectal exam cannot be performed due to severe pain when attempted. Which of the following is the most likely diagnosis?

                        A. Proctitis

                        B. Anal fissure
                        C. Rectal prolapse
                        D. Internal hemorrhoids

                        Anal fissures are covered as part of the NCCPA Content Blueprint GI and Nutrition which accounts for 10% of the exam

                        View this ReelDx patient video case of a 51-year-old with rectal bleeding and abdominal pain (proctitis)

                        Click here to see the answer

                        Answer: B. Anal fissures

                        Anal fissures are easily diagnosed from history alone with the classic finding of severe pain upon defecation. Constipation is also a common cause of the trauma that leads to the development of a fissure.

                        A. Proctitis is usually caused by anorectal infections that produce symptoms of anorectal discomfort, tenesmus, constipation, and discharge from the rectum.

                        C. Rectal prolapse is commonly seen in elderly females with complaints that include an anal mass, rectal bleeding and a change in bowel habits.
                        D. While internal hemorrhoids may cause rectal bleeding, tearing pain is an uncommon complaint unless there is evidence of thrombosis of irreducible tissue.

                        2. What type of chest pain is most commonly associated with a dissecting aortic aneurysm?

                        A. Squeezing

                        B. Dull, aching
                        C. Ripping, tearing
                        D. Burning

                        Dissecting aortic aneurysm is covered as part of the NCCPA Cardiology Content Blueprint and accounts for 16% of the exam

                        Click here to see the answer

                        Answer: C. A dissecting aortic aneurysm often presents with a very severe ripping, tearing like pain.

                        A dissecting aortic aneurysm often presents with a very severe ripping, tearing like pain.

                        A. Squeezing pain is more characteristic of angina or esophageal pain.

                        B. Dull, aching pain is more characteristic of chest wall pain, possibly angina, or anxiety.
                        D. Burning pain is more characteristic of esophageal reflux, esophagitis, or tracheobronchitis.

                        3. A 15-year-old softball player presents after jamming the distal tip of her finger into severe flexion. She is unable to extend the distal phalanx and she has pain on palpation of the distal interphalangeal joint. X-ray of the hand fails to reveal any associated avulsion fracture. Which of the following is the treatment of choice?

                        A. Open reduction and internal fixation

                        B. Continuous extension of the DIP with splinting
                        C. Continuous flexion of the PIP with splinting
                        D. Application of short arm cast

                        Soft tissue injuries of the forearm, wrist, and hand are covered as part of the NCCPA Musculoskeletal Content Blueprint and accounts for 10% of the exam

                        Click here to see the answer

                        Answer: B. Continuous extension of the DIP with splinting

                        The treatment of choice for a tear in the extensor tendon of the finger is continuous extension of the DIP via splinting for 6 to 8 weeks.

                        D. Short arm casting is indicated in wrist and metacarpal injuries but not in DIP extensor injuries.

                        4. A patient presents with loss of pigmentation on the back of hands, face, and body folds due to the absence of epidermal melanocytes. There has been improvement with PUVA treatment. Which of the following is the most likely diagnosis?

                        A. Pityriasis alba

                        B. Tinea versicolor
                        C. Vitiligo
                        D. Melasma

                        View this ReelDx patient video case of a 7-year-old female with localized, depigmented skin patches; rash

                        Click here to see the answer

                        Answer: C. Vitiligo

                         Vitiligo is the acquired loss of pigmentation due to the absence of epidermal melanocytes presenting on the back of hands, face, or body folds.

                        A. Pityriasis alba is caused by dermal inflammation that becomes scaly and hypopigmented.

                        B. Tinea versicolor is a fungal infection of the skin presenting as oval or circular lesions
                        D. Melasma is an acquired brown hyperpigmentation involving the face and neck in women during their second or third trimester of pregnancy.

                        5. Which of the following medications used in the management of anxiety has a delayed onset of action?

                        A. Buspirone (BuSpar)

                        B. Diphenhydramine (Benadryl)
                        C. Lorazepam (Ativan)
                        D. Butalbital (Fiorinal)

                        Anxiety disorders are covered as part of the NCCPA Content Psychiatry Blueprint which accounts for 6% of your exam

                        Click here to see the answer

                        Answer: A. buspirone (BuSpar)

                        Buspirone takes several days to weeks for it to have clinical activity.

                        B. Diphenhydramine works as a histamine blocker and will cause sedation immediately because of its anticholinergic effects.

                        C. Lorazepam is an anxiolytic medication that has an immediate onset of activity.
                        D. Butalbital is a short to intermediate-acting barbiturate that has immediate activity.

                        6. A 57-year-old male was working on his farm when some manure was slung hitting his left eye. He presents several days after with a red, tearing, painful eye. Fluorescein stain reveals uptake over the cornea looking like a shallow crater. Which of the following interventions would be harmful?

                        A. Ophthalmic antibiotics

                        B. Pressure patch
                        C. Examination for visual acuity
                        D. Copious irrigation

                        Corneal abrasion is covered as part of the NCCPA EENT Content Blueprint and accounts for 9% of the exam

                        Click here to see the answer

                        Answer: B. Pressure patch

                        Patching of the eye after a corneal abrasion associated with organic material contamination is contraindicated due to increased risk of fungal infection.

                        A. Ophthalmic antibiotics and copious irrigation are indicated when treating a patient with a suspected corneal ulcer due to an infectious cause.

                        C. Examination for assessment of visual acuity should be performed.

                        7. A 75-year-old female falls on her outstretched arm. She sustains a humeral mid-shaft fracture. Nerve impingement occurs due to the fracture. What is the most likely physical examination abnormality that will be encountered?

                        A. Inability to extend the wrist against resistance

                        B. Numbness over the deltoid muscle in the shoulder
                        C. Winging of the scapula
                        D. Weakness of the rotator cuff

                        Fractures and dislocations of the forearm, wrist, and hand are covered as part of the NCCPA Musculoskeletal Content Blueprint and accounts for 10% of the exam

                        Click here to see the answer

                        Answer: D. Inability to extend the wrist against resistance

                        The radial nerve is most likely entrapped by this fracture. Radial nerve damage will cause an inability to extend the wrist against resistance.

                        B. Axillary nerve injury results in numbness over the deltoid muscle; this nerve is more commonly injured in proximal humeral fractures and anterior shoulder dislocations.

                        C. Injury to the long thoracic nerve causes winging of the scapula due to its innervation of the serratus anterior muscle.
                        D. Injury to the subscapular nerve results in weakness and pain of the infraspinatus muscle; this injury is commonly seen in volleyball players from repetitive stress.

                        8. A 16-year-old male involved in a fight sustained a laceration to his right upper eyelid. He is unable to open his eye, and a possible laceration of the globe is suspected. Which of the following is the next step?

                        A. Use a slit lamp to determine the extent of the injury.

                        B. Use fluorescein strips to determine the extent of the injury.
                        C. Apply a metal eye shield and refer to an ophthalmologist.
                        D. Apply antibiotic ointment to the lid and recheck in 24 hours.

                        Disorders of they eye are covered as part of the NCCPA EENT Content Blueprint and accounts for 9% of the exam

                        66-year-old female with acute onset of periorbital deformity. SmartyPANCE ReelDx + members can view this real-world case!

                        Click here to see the answer

                        Answer: C. Apply a metal eye shield and refer to an ophthalmologist.

                        Protect the eye from any pressure with a rigid metal eye shield and refer for immediate ophthalmologic consultation. Avoid unnecessary actions that would delay treatment or cause further injury.

                        9. Which of the following typical findings would be revealed during a sigmoidoscopy on a patient with Crohn’s disease of the intestine?

                        A. Rectal pseudopolyps

                        B. Diffuse ulceration and bleeding
                        C. Sheets of WBCs with inflamed mucosa
                        D. Intermittent longitudinal mucosal ulcers and fissures

                        Inflammatory bowel disease is covered as part of the NCCPA Content Blueprint GI and Nutrition which accounts for 10% of the exam

                        Click here to see the answer

                        Answer: D. Intermittent longitudinal mucosal ulcers and fissures

                        Ulcerations tend to be linear with transverse fissures in Crohn’s disease. These skip lesions are common with Crohn’s disease.

                        A. Rectal pseudopolyps are associated with ulcerative colitis rather than Crohn’s.

                        B. Diffuse ulcerations and bleeding are more characteristic of ulcerative colitis than Crohn’s disease.
                        C. Sheets of WBCs or “pseudomembranes” can be detected in patients with pseudomembranous colitis.

                        10. A 72-year-old patient with a history of hypertension and atrial fibrillation presents with episodes of weakness, numbness, and paresthesia’s in the right arm. At the same time, she notes speech difficulty and loss of vision in her left eye. These symptoms come on abruptly and clear within minutes. Physical examination is normal except for the previously known arrhythmia. Which of the following is the most likely diagnosis?

                        A. Focal seizure

                        B. Migraine headache
                        C. Hypoglycemic episodes
                        D. Transient ischemic attack

                        Atrial fibrillation is covered as part of the NCCPA Cardiology Content Blueprint which is 16% of your exam

                        SmartyPANCE + ReelDx members can view this ReelDx patient case video of an 83-year-old with fast heart rate, palpitations

                        Click here to see the answer

                        Answer: D. Transient ischemic attack

                        This patient’s symptoms are consistent with transient ischemia in the carotid territory. Atrial fibrillation is a risk factor for cerebral emboli.

                        A. Focal seizures usually cause abnormal motor movement rather than weakness or loss of feeling.

                        B. Patients with migraines commonly have a history of episodes since adolescence.
                        C. Hypoglycemic episodes do not present with focal neurological findings.

                        Looking for all the podcast episodes?

                        This FREE series is limited to every other episode, you can download and enjoy the complete audio series by joining The PANCE and PANRE Exam Academy + SMARTYPANCE

                        I will be releasing new episodes every few weeks. The Academy is discounted, so sign up now.

                        Resources and Links From The Show
                        • Join the PANCE and PANRE Academy + Smarty PANCE
                        • My list of recommended PANCE and PANRE review books
                        • Download the FREE PANCE and PANRE Blueprint Checklist
                        • Sign up for the FREE daily PANCE and PANRE email series
                        • The Smarty PANCE NCCPA Content Blueprint Website + The PA Life Academy
                        • USE CODE “PALIFE” TO GET 10% OFF THE RUTGERS PANCE AND PANRE REVIEW COURSE
                        • This Podcast is also available on iTunes and Stitcher Radio for Android
                          1. iTunes: The Audio PANCE AND PANRE Podcast iTunes
                          2. Stitcher Radio: The Audio PANCE and PANRE Podcast Stitcher
                          3. Download The Content Blueprint Checklist

                            Follow this link to download your FREE copy of the Content Blueprint Checklist

                            Print it up and start crossing out the topics you understand, marking the ones you don’t and making notes of key terms you should remember. The PDF version is interactive and linked directly to the individual lessons on SMARTY PANCE.

                            FREE Download

                            18 min
                          4. Episode 49: The Audio PANCE and PANRE Board Review Podcast – Comprehensive Audio Quiz

                            Welcome to episode 49 of the FREE Audio PANCE and PANRE Physician Assistant Board Review Podcast.

                            Join me as I cover ten PANCE and PANRE board review questions from the Academy course content following the NCCPA™ content blueprint (download the FREE cheat sheet).

                            This week we will be covering 10 general board review questions based on the NCCPA PANCE and PANRE Content Blueprint. 

                            Below you will find an interactive exam to complement the podcast.

                            I hope you enjoy this free audio component to the examination portion of this site. The full board review includes over 2,000 interactive board review questions and is available to all members of the PANCE and PANRE Academy and SmartyPANCE.

                            • You can download and listen to past FREE episodes here, on iTunes or Stitcher Radio.
                            • You can listen to the latest episode, take an interactive quiz and download your results below.
                            • Listen Carefully Then Take The Quiz

                              If you can’t see the audio player click here to listen to the full episode.

                              Episode 49 PANCE and PANRE Podcast Quiz

                              The following 10 questions are linked to NCCPA Content Blueprint lessons from the SmartyPANCE PANCE and PANRE board review website. If you are a member and login you will be able to view this content.

                              1. Which of the following clinical findings would be seen in a patient with food poisoning caused by Staphylococcus aureus?

                              A. Ingestion of mayonnaise-based salads 48 hours earlier

                              B. Bloody diarrhea with mucus for one week
                              C. Abdominal cramps and vomiting for 48 hours
                              D. High fever for 1 week

                              Staphylococcus aureus food poisoning is part of the NCCPA Content Blueprint GI and Nutrition which accounts for 10% of the exam

                              Click here to see the answer

                              Answer: C. Abdominal cramps and vomiting for 48 hours

                              Abdominal cramps, nausea, vomiting, and watery diarrhea typically last 1-2 days with staphylococcal food poisoning.

                              A. A preformed toxin causes staphylococcal food poisoning; it has a short incubation period of 1-8 hours.

                              B. Because Staphylococcus aureus does not invade the mucus, blood and mucus are not seen with this noninflammatory cause of food poisoning.
                              D. Staphylococcal food poisoning may be associated with low-grade fever or subnormal temperature.

                              2. Which of the following diagnostic tests should be ordered initially to evaluate for suspected deep venous thrombosis

                              A. Venogram

                              B. Arteriogram
                              C. Duplex ultrasound
                              D. Impedance plethysmography

                              Venous thrombosis is part of the NCCPA Cardiology Content Blueprint and represents 16% of the exam

                              Click here to see the answer

                              Answer: C. Duplex ultrasound

                              Ultrasound is the technique of choice to detect deep venous thrombosis in the leg.

                              A. Venogram has been replaced by noninvasive tests due to discomfort, cost, technical difficulties, and complications, such as phlebitis.

                              B. Thrombophlebitis is a venous problem, not an arterial one. Any unnecessary invasive procedure is potentially harmful.
                              D. Impedance plethysmography is equivalent to ultrasound in detecting thrombi of the femoral and popliteal veins, but it may miss early, nonocclusive thrombi.

                              3. A patient presents with signs and symptoms of Cushing’s syndrome. Extensive diagnostic evaluation reveals an ACTH-secreting pituitary adenoma. First-line therapy should consist of

                              A. pituitary radiation

                              B. medical adrenalectomy
                              C. transsphenoidal resection of the tumor
                              D. amiloride (Midamor)

                              Cushings disease is part of the NCCPA Content Blueprint Endocrinology which represents 6% of your exam

                              Click here to see the answer

                              Answer: C. transsphenoidal resection of the tumor

                              Transsphenoidal resection of the tumor cures about 80% of patients. The remainder can be given a combination of pituitary radiation and medical adrenalectomy with one or more drugs. If these procedures fail, the last option is bilateral adrenalectomy.

                              4. A 26-year-old man is stung by a bee, and shortly thereafter, a wheal develops at the site of the sting. He soon feels flushed and develops hives, rhinorrhea, and tightness in the chest. He is seen in the urgent care center. Immediate therapy should be to

                              A. transfer him to a local hospital emergency department

                              B. apply a cold compress to site of the sting
                              C. administer subcutaneous epinephrine
                              D. administer oral albuterol

                              Click here to see the answer

                              Answer: C. administer subcutaneous epinephrine

                              Epinephrine hydrochloride 1:1000, 0.2 to 0.5 mL subcutaneously is indicated for the initial treatment of this systemic reaction. Additional injections may be given every 20 to 30 minutes if needed.

                              A. Systemic (anaphylactic) reactions can rapidly become life-threatening. Delay in treatment may cause death.

                              B. This is only supportive local therapy and does not address the need to treat the systemic reaction present.
                              D. Albuterol is indicated in the presence of bronchospasm (suggested by the presence of chest tightness) but would be delivered by an aerosol, not an oral, route.

                              5. An 18-year-old sexually active female was seen in the student health clinic 1 week ago for a sore throat. A streptococcal antigen test was positive, and she was given a prescription for oral penicillin. After 3 days, she stopped her medication because she felt better. She now presents with a severe sore throat. On physical examination, she has a temperature of 102.6° F (39.2° C), marked pharyngeal erythema, medial deviation of the soft palate on the left, tender left anterior cervical adenopathy, and a “hot potato” voice. The rest of her history and physical examination are unremarkable. Which of the following is the most likely diagnosis?

                              A. Recurrent streptococcal pharyngitis

                              B. Infectious mononucleosis
                              C. Gonococcal pharyngitis
                              D. Peritonsillar abscess

                              Peritonsillar abscess is covered as part of the NCCPA Content Blueprint EENT which accounts for 6% of your exam

                              View this ReelDx patient video case ~4d pain back of throat; swelling; difficulty swallowing

                              SmartyPANCE ReelDx + members can view this real-world case!

                              Click here to see the answer

                              Answer: D. Peritonsillar abscess

                              The soft palate deviation and a muffled voice are classic signs of peritonsillar abscess.

                              A. This presentation suggests a complication of an incompletely treated streptococcal pharyngitis rather than recurrent disease

                              B. Infectious mononucleosis may present with a severe sore throat and cervical adenopathy in this age group, but would not cause deviation of the soft palate or the muffled voice
                              C. Gonococcal pharyngitis usually follows a more indolent course than this patient’s presentation

                              6. Which of the following would provide the most specific information regarding the functional cardiac status in a patient with chronic heart failure?

                              A. Electrocardiogram

                              B. Chest x-ray
                              C. Serum electrolytes
                              D. Echocardiogram

                              Heart Failure is covered as part of the NCCPA Content Blueprint Cardiology and accounts for 16% of the exam

                              View this SMARTYPANCE ReelDx patient video case: 45-year-old female with difficulty breathing; edema; 8/10 chest pain and whole-body pain

                              SmartyPANCE ReelDx + members can view this real-world case!

                              Click here to see the answer

                              Answer: D. Echocardiogram

                              An echocardiogram will estimate ejection fraction, which is an indicator of left ventricular function.

                              A. Electrocardiogram offers no specific information of functional status but may provide clues about the cause.

                              B. A chest x-ray may show findings of chronic heart failure, such as cardiomegaly or pulmonary congestion, but does not reflect cardiac functional status.
                              C. Serum electrolytes may be abnormal, either as a result of heart failure, or as a contributing factor, but they do not indicate functional status.

                              7.  A 33-year-old female presents for follow-up of her Pap smear that showed a low-grade squamous intraepithelial lesion. Reflex HPV testing is positive. Which of the following is the most appropriate diagnostic procedure?

                              A. Cone biopsy

                              B. Aspiration needle biopsy
                              C. Dilation and curettage
                              D. Colposcopy-directed biopsy

                              Cervical dysplasia and cervical cancer are covered as part of the NCCPA Content Blueprint Reproductive system and accounts for 8% of your exam

                              Click here to see the answer

                              Answer: D. Colposcopy-directed biopsy

                              A colposcopy-directed biopsy is the first diagnostic evaluation indicated for cervical dysplasia.

                              A. A cervical cone biopsy may be indicated in further evaluation of this patient, but it is dependent on the results of the colposcopy.

                              B. An aspiration needle biopsy has no role in the evaluation of cervical dysplasia.
                              C. Dilatation and curettage has no role in either the diagnosis or treatment of isolated cervical dysplasia.

                              8. A decrease in the fetal heart rate (FHR) occurring late during contractions is noted. The FHR returns to the baseline slowly after the uterine contraction. The physician assistant should be alerted to the possibility of

                              A. pelvic dystocia

                              B. precipitous labor
                              C. fetal head compression
                              D. placental insufficiency

                              Fetal distress is covered as part of the NCCPA Content Blueprint Reproductive system and accounts for 8% of your exam

                              SmartyPANCE ReelDx + members can view this real-world case!

                              Click here to see the answer

                              Answer: D. placental insufficiency

                              Placental insufficiency is the probable cause of fetal distress resulting in late decelerations.

                              A. Pelvic dystocia, particularly that due to small bony architecture, is the most common cause of passage abnormalities and is not directly associated with FHR decelerations.

                              B. This refers to the length of labor, not decelerations in FHR.
                              C. The drop in FHR is caused by an interference with uterine blood flow to the intervillous space causing an early, not late, deceleration.

                              9. A 36-year-old patient with cardiomyopathy secondary to viral myocarditis develops fatigue, increasing dyspnea, and lower extremity edema over the past 3 days. He denies fever. A chest x-ray shows no significant increase in heart size but reveals prominence of the superior pulmonary vessels. Based on these clinical findings, which of the following is the most likely diagnosis?

                              A. Heart failure

                              B. Subacute bacterial endocarditis
                              C. Pulmonary embolus
                              D. Pneumonia

                              Heart Failure is covered as part of the NCCPA Content Blueprint Cardiology and accounts for 16% of the exam

                              Click here to see the answer

                              Answer: A. Heart failure

                              Given the presence of cardiomyopathy, the patient’s heart has decreased functional reserve. The symptoms and chest x-ray findings are typical of congestive heart failure.

                              B. Endocarditis occurs as a result of an infection that primarily occurs in the blood stream. Endocarditis would present with signs of infection or seeding rather than signs of heart failure.

                              C. Pulmonary embolus usually presents with an acute onset of chest pain, severe dyspnea, and anxiety.
                              D. Pneumonia is less likely since there is no fever and edema is not usually associated with pneumonia.

                              10. Which of the following is the first-line treatment for symptomatic bradyarrhythmias due to sick sinus syndrome (SSS)?

                              A. Permanent pacemaker

                              B. Radiofrequency ablation
                              C. Antiarrhythmics
                              D. Anticoagulation therapy

                              Sick sinus syndrome is covered as part of the NCCPA Cardiology Content Blueprint which is 16% of your exam

                              Click here to see the answer

                              Answer: A. Permanent pacemaker

                              Permanent pacemakers are the therapy of choice in patients with symptomatic bradyarrhythmias in sick sinus syndrome.

                              B. Radiofrequency ablation is used for the treatment of accessory pathways in the heart.

                              Looking for all the podcast episodes?

                              This FREE series is limited to every other episode, you can download and enjoy the complete audio series by joining The PANCE and PANRE Exam Academy + SMARTYPANCE

                              I will be releasing new episodes every few weeks. The Academy is discounted, so sign up now.

                              Resources and Links From The Show
                              • Join the PANCE and PANRE Academy + Smarty PANCE
                              • My list of recommended PANCE and PANRE review books
                              • Download the FREE PANCE and PANRE Blueprint Checklist
                              • Sign up for the FREE daily PANCE and PANRE email series
                              • The Smarty PANCE NCCPA Content Blueprint Website + The PA Life Academy
                              • USE CODE “PALIFE” TO GET 10% OFF THE RUTGERS PANCE AND PANRE REVIEW COURSE
                              • This Podcast is also available on iTunes and Stitcher Radio for Android
                                1. iTunes: The Audio PANCE AND PANRE Podcast iTunes
                                2. Stitcher Radio: The Audio PANCE and PANRE Podcast Stitcher
                                3. Download The Content Blueprint Checklist

                                  Follow this link to download your FREE copy of the Content Blueprint Checklist

                                  Print it up and start crossing out the topics you understand, marking the ones you don’t and making notes of key terms you should remember. The PDF version is interactive and linked directly to the individual lessons on SMARTY PANCE.

                                  FREE Download

                                  19 min
                                4. Episode 47: The Audio PANCE and PANRE Podcast – Mixed Content Blueprint Board Review

                                  Welcome to episode 47 of the FREE Audio PANCE and PANRE Physician Assistant Board Review Podcast.

                                  Join me as I cover 10 PANCE and PANRE board review questions from the Academy course content following the NCCPA™ content blueprint (download the FREE cheat sheet).

                                  This week we will be covering 10 general board review questions based on the NCCPA PANCE and PANRE Content Blueprint. 

                                  Below you will find an interactive exam to complement the podcast.

                                  I hope you enjoy this free audio component to the examination portion of this site. The full genitourinary board review includes over 72 GU specific questions and is available to all members of the PANCE and PANRE Academy and SmartyPANCE

                                  • You can download and listen to past FREE episodes here, on iTunes or Stitcher Radio.
                                  • You can listen to the latest episode, take an interactive quiz and download your results below.
                                  • Listen Carefully Then Take The Quiz

                                    If you can’t see the audio player click here to listen to the full episode.

                                    Episode 47 PANCE and PANRE Podcast Quiz

                                    The following 10 questions are linked to NCCPA Content Blueprint lessons from the SmartyPANCE PANCE and PANRE board review website. If you are a member and login you will be able to view this content.

                                    1. To relieve dependent edema in a pregnant patient, which of the following should be instituted as treatment?

                                    1. Limit fluid intake
                                    2. Elevate the legs
                                    3. Prescribe thiazide diuretics
                                    4. Strict avoidance of sodium
                                    5. Uncomplicated pregnancy is part of the NCCPA Content Blueprint Reproductive System which is 8% of the exam

                                      Click here to see the answer

                                      Answer: B. Elevate the legs.

                                      Dependent edema is a common and rarely serious complication of pregnancy due to impedance of venous return. Leg elevation improves circulation

                                      A. Limitation of fluid is not indicated and may be harmful.

                                      C. Thiazide diuretics are contraindicated and could be harmful.
                                      D. Edema due to impedance of venous return will not respond to sodium restriction.

                                      2. To further assess ascites in a patient, the physician assistant instructs the patient to turn onto one side while performing percussion. Which of the following is the reason for this maneuver?

                                      1. Testing for shifting of dullness on percussion
                                      2. Shifting of internal organs making percussion easier
                                      3. Trying to elicit any pain while moving
                                      4. Trying to produce a caput medusae
                                      5. Ascites is a common complication of liver disease. Disorders of the liver is part of the NCCPA GI and Nutrition Content Blueprint and represents 10% of the exam

                                        Click here to see the answer

                                        Answer:  A. Testing for shifting of dullness on percussion.

                                        In ascites, dullness shifts to the more dependent side as the fluid relocates into dependent space, while tympany shifts to the top as the gas-filled organs float to the top of the ascitic fluid

                                        C. Pain with movement is associated with peritonitis and not ascites.

                                        D. Caput medusae is the dilation of the superficial abdominal veins due to increased intra abdominal fluid accumulation. It is visible with the patient standing and does not need a special maneuver for identification.

                                        3.  A 7-year-old child with a history of type 1 diabetes mellitus for 3 years presents for routine follow-up. The mother states that the child has been having nightmares and night sweats. Additionally, his average morning glucose readings have risen from an average of 100 mg/dL to 145 mg/dL over the past week. This child is most likely experiencing

                                        1. a growth spurt
                                        2. emotional problems
                                        3. the Somogyi effect
                                        4. the dawn phenomenon
                                        5. Diabetes mellitus type 1 is part of the NCCPA Content Blueprint Endocrinology which represents 6% of your exam

                                          Click here to see the answer

                                          Answer: C. the Somogyi effect.

                                          This refers to nocturnal hypoglycemia, which stimulates counterregulatory hormone release resulting in rebound hyperglycemia

                                          A. Nightmares and night sweats are not associated with growth spurts.

                                          B. With this limited history, it is impossible to label the child as emotionally unstable.
                                          D. This refers to an early morning rise in plasma glucose due to reduced tissue sensitivity to insulin between 5AM and 8AM. It is not associated with nightmares and night sweats.

                                          4. A patient complains of loss of sensation at the level of the umbilicus. Which of the following dermatomes is affected?

                                          1. T6
                                          2. T8
                                          3. T10
                                          4. T12
                                          5. Radicular pain is a common symptom of a herniated nucleus pulposus covered as part of the NCCPA Content Blueprint Musculoskeletal System which is 10% of your exam

                                            Click here to see the answer

                                            Answer: C. T10.

                                            The dermatome T10 is at the level of the umbilicus.

                                            5. A 25-year-old female graduate student presents to the student health center for the eighth time in three weeks to be sure she does not have meningitis. She read that there was a student on campus who had meningitis last month, and now she has headaches and is requesting to be tested to make sure she does not have meningitis. She has been evaluated at each visit, and physical examination has been completely normal each time. Which of the following is the most likely diagnosis?

                                            1. Conversion disorder
                                            2. Hypochondriasis
                                            3. Malingering
                                            4. Somatization disorder
                                            5. Somatoform disorders are covered as part of the NCCPA Content Blueprint Psychiatry which is 6% of your exam

                                              Click here to see the answer

                                              Answer: B. Hypochondriasis.

                                              Hypochondriasis is the chronic preoccupation with the idea of having a serious disease, which is usually not amenable to reassurance

                                              A. Conversion disorder is characterized by onset of symptoms or deficits mimicking neurologic or medical illness, but the etiology is psychological.

                                              C. Malingering is the intentional production or feigning of physical or psychological signs and symptoms for some gain.
                                              D. Somatization disorder is characterized by complaints of pain, often related to gastrointestinal and sexual dysfunction, and pseudoneurological symptoms

                                              6. What is the mechanism for the relapsing fevers associated with malaria?

                                              1. Release of malarial merozoites into the bloodstream
                                              2. Release of toxins from Plasmodium species
                                              3. Attachment of Plasmodium species to receptor sites on the red blood cells
                                              4. Invasion of hepatocytes by Plasmodium species
                                              5. Malaria is covered as part of the NCCPA Content Blueprint Infectious Disease and is 3% of the exam

                                                Click here to see the answer

                                                Answer: A. Release of malarial merozoites into the bloodstream.

                                                Fever, chills, and sweats coincide with the release of merozoites from red blood cells that have been infected with Plasmodium species. Each merozoite may infect a new red blood cell, leading to a cycle of invasion growth, and release.

                                                7. A 29-year-old patient with idiopathic thrombocytopenia purpura (ITP) is treated with prednisone therapy. Despite therapy, platelet counts remain consistently below 20,000/microliter over the course of 6 weeks. Which of the following is the most appropriate intervention for this patient?

                                                1. Aspirin
                                                2. Intravenous immunoglobulin
                                                3. Danazol (Danocrine)
                                                4. Splenectomy
                                                5. Idiopathic thrombocytopenic purpura is covered as part of the NCCPA Content Blueprint Hematology and is 3% of your exam

                                                  Click here to see the answer

                                                  Answer: D. Splenectomy

                                                  Persistently low platelet counts (< 20,000) require effective long-term treatment, and splenectomy is the treatment of choice.

                                                  A. Aspirin inhibits platelet function and could lead to significant bleeding and death of this patient.

                                                  B. Intravenous immunoglobulin can be utilized for short-term treatment, but the platelet count is likely to return to baseline within a month.
                                                  C. Danazol is typically reserved for ITP that fails to respond to splenectomy.

                                                  8. A 27 year-old female presents to your office for evaluation of weakness, visual loss, and sensory loss over the right great toe. These symptoms have occurred during three episodes approximately three months apart with each episode lasting about three days. Which of the following tests would be most useful in further evaluating this patient?

                                                  1. MRI of the brain
                                                  2. Electromyography
                                                  3. Glucose tolerance test
                                                  4. Electroencephalograph
                                                  5. This condition is covered as part of the NCCPA Content Blueprint Neurology which is 6% of your exam

                                                    SmartyPANCE ReelDx + members can view this real-world case!

                                                    Click here to see the answer

                                                    Answer: A. MRI of the brain.

                                                    Multiple sclerosis typically presents with relapsing weakness of the limbs, sensory loss, paresthesias, and visual changes. Diagnosis is based on history and either abnormal brain or spinal cord MRI, or visual, auditory, or somatosensory evoked electrical response.

                                                    C. Glucose tolerance test is used in the evaluation of diabetes mellitus.

                                                    D. Electroencephalograph is used to evaluate patients for possible seizure disorder.

                                                    9. A patient taking bleomycin (Blenoxane) should be monitored for which of the following side effects?

                                                    1. Optic neuritis
                                                    2. Hyperuricemia
                                                    3. Encephalopathy
                                                    4. Pulmonary fibrosis
                                                    5. This condition is is covered as part of the NCCPA Pulmonary Content Blueprint which represents 12% of your exam

                                                      Click here to see the answer

                                                      Answer: D. Pulmonary fibrosis.

                                                      Pulmonary fibrosis and pulmonary infiltrates are known side effects of bleomycin

                                                      A. Optic neuritis is a potential side effect of ethambutol, used in the treatment of tuberculosis.

                                                      B. Hyperuricemia or encephalopathy are not known side effects of bleomycin.

                                                      10. A patient presents for a follow-up visit for chronic hypertension. Which of the following findings may be noted on the fundoscopic examination of this patient?

                                                      1. cherry-red fovea
                                                      2. boxcar segmentation of retinal veins
                                                      3. papilledema
                                                      4. arteriovenous nicking
                                                      5. This condition is a common complications of chronic hypertension covered as part of the NCCPA Cardiology Content Blueprint which is 16% of your exam

                                                        Click here to see the answer

                                                        Answer: D. arteriovenous nicking

                                                        Arteriovenous nicking is common in chronic hypertension

                                                        A. Cherry-red fovea and boxcar segmentation of the retinal veins are findings seen in central retinal artery occlusion.

                                                        C. Papilledema is noted in conditions causing increased intracranial pressure.

                                                        Looking for all the podcast episodes?

                                                        This FREE series is limited to every other episode, you can download and enjoy the complete audio series by joining The PANCE and PANRE Exam Academy + SmaryPANCE

                                                        I will be releasing new episodes every few weeks. The Academy is discounted, so sign up now.

                                                        Resources and Links From The Show
                                                        • Join the PANCE and PANRE Academy + Smarty PANCE
                                                        • My list of recommended PANCE and PANRE review books
                                                        • Download the FREE PANCE and PANRE Blueprint Checklist
                                                        • Sign up for the FREE daily PANCE and PANRE email series
                                                        • The Smarty PANCE NCCPA Content Blueprint Website + The PA Life Academy
                                                        • USE CODE “PALIFE” TO GET 10% OFF THE RUTGERS PANCE AND PANRE REVIEW COURSE
                                                        • This Podcast is also available on iTunes and Stitcher Radio for Android
                                                          1. iTunes: The Audio PANCE AND PANRE Podcast iTunes
                                                          2. Stitcher Radio: The Audio PANCE and PANRE Podcast Stitcher
                                                          3. Download The Content Blueprint Checklist

                                                            Follow this link to download your FREE copy of the Content Blueprint Checklist

                                                            Print it up and start crossing out the topics you understand, marking the ones you don’t and making notes of key terms you should remember. The PDF version is interactive and linked directly to the individual lessons on SMARTY PANCE.

                                                            FREE Download

                                                            18 min
                                                          4. Murmur Madness: The Audio PANCE and PANRE Episode 45

                                                            Welcome to episode 45 of the FREE Audio PANCE and PANRE Physician Assistant Board Review Podcast.

                                                            Today we are going to take a brief detour away from 10 daily questions and instead cover the murmurs you need to know for your PANCE and PANRE exam.

                                                            I have still included an 11 question exam at the end of this post so make sure you scroll down after you listen to the podcast.

                                                            There are a total of 17 cardiac conditions that may present on exam day in the form of a descriptive sound/murmur.

                                                            You will often be given supporting evidence such as the location of auscultation or radiation which you can use to narrow down your options.

                                                            There are total of 51 cardiac topics in the  NCCPA™ Cardiology PANCE and PANRE Content Blueprint which represents 16% of the PANCE and PANRE exam.

                                                            (click here to download the FREE NCCPA Content Blueprint cheat sheet)

                                                            These cardiac conditions and their associated murmurs cover a whopping 33% of the cardiology section of the PANCE and PANRE exam!

                                                            Take a listen to this week’s podcast episode

                                                            If you can’t see the audio player click here to listen to the full episode.

                                                            Let’s break this all down:

                                                            Each of the links below opens the corresponding lesson on SmartyPANCE and is available to members (you must be logged in or join now)

                                                            There are 9 valvular disorders associated with murmurs:

                                                            Valvular Disorders (PEARLS and Flashcards)

                                                            1. Aortic stenosis (ReelDx)
                                                            2. Aortic regurgitation (Diastolic Murmur)
                                                            3. Mitral stenosis (Diastolic)
                                                            4. Mitral regurgitation
                                                            5. Mitral valve prolapse
                                                            6. Tricuspid stenosis
                                                            7. Tricuspid regurgitation
                                                            8. Pulmonary stenosis
                                                            9. Pulmonary regurgitation
                                                            10. Five congenital heart diseases that have corresponding murmurs

                                                              Congenital Heart Diseases (PEARLS)

                                                              1. Atrial septal defect
                                                              2. Coarctation of the aorta
                                                              3. Patent ductus arteriosus
                                                              4. Tetralogy of Fallot
                                                              5. Ventricular septal defect
                                                              6. One murmur associated with cardiomyopathy

                                                                1. Hypertrophic cardiomyopathy
                                                                2. And a pair of conditions nested under the label of “other forms of heart disease” that have associated murmurs/heart sounds worth mentioning

                                                                  Other Forms of Heart Disease (PEARLS)

                                                                  1. Acute and subacute bacterial endocarditis
                                                                  2. Acute pericarditis
                                                                  3. Making Sense of Murmurs

                                                                    Let’s start with the valvular disorders:

                                                                    You have 4 heart valves with two main conditions – half are diastolic murmurs and half are systolic murmurs. Here is a helpful mnemonic:

                                                                    Recalling Common Systolic Heart Murmurs: MR PASS

                                                                    • M itral
                                                                    • R egurgitation
                                                                    • P hysiologic (also known as functional, systolic flow murmur, a heart murmur heard in the absence of cardiac abnormality)
                                                                    • A ortic
                                                                    • S tenosis
                                                                    • S ystolic – All the above murmurs are heard during systole.
                                                                    • MR PASS wins the Most Valuable Player award.

                                                                      • M itral
                                                                      • V alve
                                                                      • P rolapse – Add MVP as another systolic murmur.
                                                                      • MR PASS often hangs around with MS ARD.

                                                                        • M itral
                                                                        • S tenosis
                                                                        • A ortic
                                                                        • R egurgitation
                                                                        • D iastolic – All the above murmurs are heard during diastole.
                                                                        • Here are the nine valvular murmurs and their associated descriptions

                                                                          Remember which are systolic and diastolic this can be very helpful at ruling out or ruling in a condition come exam day.

                                                                          1. Aortic Stenosis – Systolic harsh ejection crescendo decrescendo murmur at RUSB (aortic area) with radiation to the neck and apex
                                                                          2. Aortic Regurgitation – diastolic – soft high pitched blowing at LSB with patient sitting leaning forward and exhaling
                                                                          3. Mitral stenosis – diastolic – low pitched decrescendo rumbling with opening snap at the APEX (the mitral area) enhanced by expiration
                                                                          4. Mitral regurgitation – blowing holosystolic murmur loudest at the APEX (the mitral area) with a split S2 that radiates to the axilla and is increased by squatting, handgrip and expiration
                                                                          5. Tricuspid Stenosis – diastolic – mid diastolic rumbling at LLSB (tricuspid area) with opening snap
                                                                          6. Tricuspid regurgitation – High pitched holosystolic blowing murmur that radiates to the LSB (tricuspid area)
                                                                          7. Pulmonic stenosis – harsh midsystolic ejection crescendo-decrescendo murmur with widely split s2 at LSB that radiates to the left shoulder and neck
                                                                          8. Pulmonic regurgitation – diastolic –  high pitched, decrescendo murmur at LUSB increase with inspiration
                                                                          9. Mitral valve prolapse – Midsystolic ejection click head best at the APEX (the mitral area)
                                                                          10. With these valvular murmurs you have 4 auscultation points which can be easily remembered using the mnemonic APT Ment watch this amazing video so you never forget!

                                                                            Another helpful mnemonic: Aortic Pulmonic Tricuspid Mitral – A ll P hysicians T ake M oney!

                                                                            1. Aortic area: right 2nd interspace (Right upper sternal border RUSB)
                                                                            2. Pulmonic area: 2nd left interspace (Left upper sternal border LUSB)
                                                                            3. Tricuspid area: Left lower sternal border LLSB
                                                                            4. Mitral area: APEX
                                                                            5. You can use the auscultation point to successfully narrow down your murmur and use the designation of systolic or diastolic to narrow down even further.

                                                                              Five congenital heart diseases that have corresponding murmurs

                                                                              Congenital Heart Diseases (PEARLS)

                                                                              1. Atrial septal defect – Systolic ejection murmur at 2nd left intercostal space with an early to mid-systolic rumble and fixed splitting of the 2nd heart sound (s2) and CXR will show pulmonary vascular markings.
                                                                              2. Coarctation of the aorta – Late systolic ejection murmur-posterior or continuous murmur if collateral flow. Will have absent or weak femoral pulses with a delay of palpable femoral pulse and HTN in arms but low or normal blood pressure in the legs
                                                                              3. Patent ductus arteriosus – Continuous, rough, machinery-like murmur, heard best in the first interspaces of the LSB
                                                                              4. Tetralogy of Fallot – Harsh systolic ejection murmur heard best at the left sternal border. Associated with bluish skin, trouble gaining weight, and sudden loss of consciousness during crying or feeding
                                                                              5. Ventricular septal defect – Harsh high pitched holosystolic murmur heard best at the LSB with ride radiation and a fixed split S2
                                                                              6. Several of these conditions have a “tell” that make it easy to identify the condition and they are usually always part of the root of the question.

                                                                                • PDA = machinery like murmur (remember that the physician assistant got a patent on his machine).
                                                                                • Tetralogy of Fallot usually presents with a young child having TET spells which are described as bluish skin, trouble gaining weight, and sudden loss of consciousness during crying or feeding. 
                                                                                • Coarctation will almost always present with absent or weak femoral pulses with a delay of palpable femoral pulse and HTN in arms but low or normal blood pressure in the legs. 
                                                                                • ASD is a bit tougher but they will usually give you a wide and fixed splitting of the S2 and patients will be easily fatigued. CXR will show pulmonary vascular markings.
                                                                                • VSD will have a high pitched holosystolic murmur and newborns may show dyspnea.
                                                                                • One murmur associated with cardiomyopathy
                                                                                  1. Hypertrophic cardiomyopathy – Medium-pitched, mid-systolic murmur that decreases with squatting and increases with straining. S4 gallop and apical lift with thick, stiff left ventricle. HCM is the leading cause of sudden death in athletes and may cause angina.
                                                                                  2. And a pair of conditions nested under the label of “other forms of heart disease” that have associated murmurs/heart sounds worth mentioning

                                                                                    Other Forms of Heart Disease (PEARLS)

                                                                                    1. Acute and subacute bacterial endocarditis  – A new mitral regurgitant murmur in a patient with a history of IVDA, fever (39.0º C),* and a blood culture that reveals 2 out of 2 positive growth
                                                                                    2. Acute pericarditis – Although this is not a murmur, it is important to identify a pericardial friction rub heard best with patient upright and leaning forward. Chest pain is also relieved by sitting and/or leaning forward
                                                                                    3. You can listen to all these murmurs and see their associated waveforms at www.smartypance.com/courses/cardiology

                                                                                      Here is a wonderful video from the Khan Academy of how to approach murmurs video of murmurs

                                                                                      Murmur Flash Cards

                                                                                      Episode 45 PANCE and PANRE Murmur Quiz

                                                                                      You will see from these questions on the PANCE and PANRE things aren’t always so straightforward.

                                                                                      You can take the exam here: thepalife.com/murmur-madness

                                                                                      Looking for all the podcast episodes?

                                                                                      This FREE podcast series is limited to every other episode, you can download and enjoy the complete audio series by joining The PANCE and PANRE Exam Academy + SmartyPANCE

                                                                                      I will be releasing new episodes every few weeks. The Academy is discounted and now includes complimentary access to SmartyPANCE so sign up now.

                                                                                      Included is a full cardiology content blueprint board review exam with over 147 cardiology specific questions and 51 cardiology blueprint topics covered in detail. This is in addition to 1,000’s of additional board review questions and NCCPA content blueprint courses covering all 13 organ areas.

                                                                                      I am also happy to introduce ReelDX™ patient case based integration into many of the SmartyPANCE blueprint lessons. It’s like a virtual rotation from the comfort of your couch!

                                                                                      This podcast is available on iTunes and Stitcher Radio (among others)
                                                                                      1. iTunes: The Audio PANCE AND PANRE Podcast iTunes
                                                                                      2. Stitcher Radio: The Audio PANCE and PANRE Podcast Stitcher
                                                                                      3. 15 min
                                                                                      4. Episode 43: The Audio PANCE and PANRE Board Review Podcast

                                                                                        Welcome to episode 43 of the FREE Audio PANCE and PANRE Physician Assistant Board Review Podcast.

                                                                                        Join me as I cover 10 PANCE and PANRE board review questions from the Academy course content following the NCCPA™ content blueprint (download the FREE cheat sheet).

                                                                                        This week we will continue to take a break from topic specific board review and covering 10 general board review questions.

                                                                                        Below you will find an interactive exam to complement the podcast.

                                                                                        I hope you enjoy this free audio component to the examination portion of this site. The full genitourinary board review includes over 72 GU specific questions and is available to all members of the PANCE and PANRE Academy.

                                                                                        • You can download and listen to past FREE episodes here, on iTunes or Stitcher Radio.
                                                                                        • You can listen to the latest episode, take an interactive quiz and download your results below.
                                                                                        • Listen Carefully Then Take The Quiz

                                                                                          If you can’t see the audio player click here to listen to the full episode.

                                                                                          Episode 43 PANCE and PANRE Podcast Quiz

                                                                                          1. A mother brings in her five-year-old boy for his school physical. She voices some concerns about his readiness for school, saying he seems to be socially immature. She has noticed he does not interact with other children well, and that when he plays with them, he has a tendency to “place them” and then run around them as if they were statues. He rarely cries when he is hurt, and he shrugs off any attempt to hug him. He has good attention to details, and will sit and draw the same geometric shapes over and over again, but does not seem interested in learning the alphabet. He avoids eye contact with anyone. Which of the following is the most likely diagnosis?

                                                                                          1. Normal 5 year-old
                                                                                          2. Social phobia
                                                                                          3. Autism
                                                                                          4. Avoidant personality
                                                                                          5. Click here to see the answer

                                                                                            Answer: C. Autism

                                                                                            Children with autism do not tend to make eye contact, and even avoid it. They do not accept comfort when hurt and stiffen up when hugged. They do not tend to play with others, and do not tend to imitate grown-ups in play.

                                                                                            They approach play in a more mechanical way, using others as props rather than interacting with them.

                                                                                            Explanations

                                                                                            • A. This behavior is not normal for a child this age.
                                                                                            • B. Social phobia is an excessive and persistent fear of social situations in which the person may be scrutinized by others.
                                                                                            • D. Avoidant personality disorder is characterized by timidity, social awkwardness, and a pervasive sense of inadequacy and fear of criticism.
                                                                                            • 2. A 3-week-old male infant presents with recurrent regurgitation after feeding that has progressed to projectile vomiting in the last few days. The mother states that the child appears hungry all of the time. She denies any diarrhea in the child. Which of the following clinical findings is most likely?

                                                                                              1. Bile-stained vomitus
                                                                                              2. Hemoccult positive stools
                                                                                              3. Olive-sized mass in the right upper abdomen
                                                                                              4. Sausage-shaped mass in the upper-mid abdomen
                                                                                              5. Click here to see the answer

                                                                                                Answer: C. Olive-sized mass in the right upper abdomen

                                                                                                An olive-sized mass may be palpated in the right upper abdomen in pyloric stenosis and if found, is pathognomonic for pyloric stenosis.

                                                                                                Explanations

                                                                                                • D. A sausage-shaped mass may be noted in intussusception, not pyloric stenosis.
                                                                                                • A. Gastric obstruction, such as that seen with pyloric stenosis, causes vomiting that is not bilious.
                                                                                                • B. Blood-streaked vomitus, but not hemoccult positive stools, may be seen in pyloric stenosis.
                                                                                                • 3. A 65 year-old with COPD receiving their first pneumococcal polysaccharide PPSV23 vaccination should be revaccinated in

                                                                                                  1. 1 year
                                                                                                  2. 3 years
                                                                                                  3. 5 years
                                                                                                  4. Never
                                                                                                  5. Click here to see the answer

                                                                                                    Answer: D. Never

                                                                                                    People who are first vaccinated with PPSV23 at age 65 years or older should receive only 1 dose, regardless of their underlying medical condition.

                                                                                                    ACIP recommendations for revaccination remain unchanged from the 1997 recommendations. For most persons for whom PPSV23 is indicated, ACIP does not recommend routine revaccination. A second dose of PPSV23 is recommended 5 years after the first dose for persons aged 19–64 years with functional or anatomic asplenia and for persons with immunocompromising conditions . ACIP does not recommend multiple revaccinations because of insufficient data regarding clinical benefit, particularly the degree and duration of protection, and safety.

                                                                                                    All adults age 65 years and older should also receive one dose of PCV13.

                                                                                                    Click here to review the CDC guidelines

                                                                                                    4. Which of the following therapies is recommended for a 13 month-old child with sickle cell disease?

                                                                                                    1. Folic acid and penicillin V
                                                                                                    2. Ferrous sulfate and penicillin V
                                                                                                    3. Folic acid and ferrous sulfate
                                                                                                    4. Folic acid, ferrous sulfate and penicillin V
                                                                                                    5. Click here to see the answer

                                                                                                      Answer: A. Folic acid and penicillin V

                                                                                                      Patients with sickle cell disease should receive prophylactic penicillin V starting at 2 months of age and folic acid starting at 1 year of age. Ferrous sulfate is not globally recommended for patients with sickle cell disease.

                                                                                                      5. A patient with severe COPD presents to the Emergency Department with a 3 day history of increasing shortness of breath with exertion and cough productive of purulent sputum. An arterial blood gas reveals a pH of 7.25, PaCO2 of 70 mmHg and PaO2 of 50 mmHg. He is started on albuterol nebulizer, nasal oxygen at 2 liters per minute, and an IV is started. After one hour of treatment, his arterial blood gas now reveals a pH of 7.15, PaCO2 100 mmHg and PaO2 of 70 mmHg. Which of the following is the most appropriate next step in his treatment?

                                                                                                      A. Decrease the oxygen flow rate.

                                                                                                      B. Administer oral corticosteroids.
                                                                                                      C. Intubate the patient.
                                                                                                      D. Administer salmeterol (Serevent)

                                                                                                      Click here to see the answer
                                                                                                      Answer: C. Intubate the patient.

                                                                                                      This person has increasing respiratory failure as indicated by the raising PaCO2 levels. Intubation is required at this time.

                                                                                                      Explanations

                                                                                                      • A. Decreasing the oxygen flow rate would be harmful as it would decrease the amount of oxygen delivered to the patient.
                                                                                                      • B. Administration of steroids is an important treatment modality but this patient is in respiratory failure and needs more immediate therapy.
                                                                                                      • D. Long-acting beta agonist therapy such as salmeterol is not utilized for rescue therapy.
                                                                                                      • 6. A patient should be tested for tuberculosis prior to being treated with

                                                                                                        A. etanercept (Enbrel).

                                                                                                        B. cyclosporine (Neoral).
                                                                                                        C. methotrexate (Rheumatrex).
                                                                                                        D. prednisone (Deltasone).

                                                                                                        Click here to see the answer

                                                                                                        Answer: A. etanercept (Enbrel)

                                                                                                        Etanercept is an anti-cytokine agent used in the treatment of rheumatoid arthritis and has as a side effect the potential for serious infections. One of these side effects includes reactivation of dormant tuberculosis.

                                                                                                        Explanations

                                                                                                        B. Cyclosporine, methotrexate, and prednisone do not have the requirement to check for tuberculosis prior to initiating treatment.

                                                                                                        7. Which of the following side effects is associated with long-term administration of phenytoin (Dilantin)?

                                                                                                        A. Ataxia

                                                                                                        B. Hypotension
                                                                                                        C. Osteomalacia
                                                                                                        D. Cardiac dysrhythmia

                                                                                                        Click here to see the answer

                                                                                                        Answer: C. Osteomalacia

                                                                                                        Osteomalacia, or demineralization of bone, is a side effect of phenytoin that may occur after chronic administration.

                                                                                                        Explanations

                                                                                                        • A. Ataxia is associated most often with acute oral overdosage of phenytoin.
                                                                                                        •  B. Cardiac dysrhythmia, with or without hypotension, is an expected side effect of rapid IV phenytoin administration.
                                                                                                        • 8. Hairy leukoplakia has the greatest prevalence of distribution on the

                                                                                                          A. palate.

                                                                                                          B. floor of the mouth.
                                                                                                          C. lateral tongue.
                                                                                                          D. gingiva.

                                                                                                          Click here to see the answer

                                                                                                          Answer: C. lateral tongue.

                                                                                                          The lateral border of the tongue is where hairy leukoplakia is commonly seen.

                                                                                                          9. 75 year-old male presents for a routine physical. Vitals are normal with no orthostatic changes. On physical examination, a fine cortical movement with repetitive rubbing of the tip of the thumb along the tips of the fingers is noted at rest. Which of the following is the most likely diagnosis?

                                                                                                          A. Seizure disorder

                                                                                                          B. Peripheral neuropathy
                                                                                                          C. Shy-Drager syndrome
                                                                                                          D. Parkinson's disease

                                                                                                          Click here to see the answer
                                                                                                          Answer: D. Parkinson’s disease

                                                                                                          Parkinson’s disease presents with tremor at rest (pill-rolling), bradykinesia, rigidity, and postural instability.

                                                                                                          Explanations

                                                                                                          • A. While a seizure may present with fine or gross uncontrolled motor movements, the tremor described is classic pill-rolling tremor noted in Parkinson’s disease.
                                                                                                          • B. Peripheral neuropathy presents with loss of sensation not tremor.
                                                                                                          • C. Shy-Drager syndrome is due to autonomic degeneration and typically presents with orthostatic hypotension.
                                                                                                          • 10. A 45 year-old female presents to the emergency department with generalized, hot, erythema of the skin. Physical exam reveals an oral temperature of 102 degrees Fahrenheit, purulent conjunctivitis, and mucosal erosions. Her skin is painful and separates from the dermis with touch. Which of the following is the most likely cause for this condition?

                                                                                                            A. Penicillin

                                                                                                            B. Prednisolone
                                                                                                            C. Aspirin
                                                                                                            D. Hydrochlorothiazide (HCTZ)

                                                                                                            Click here to see the answer

                                                                                                            Answer: A. Penicillin

                                                                                                            Medications are most frequently implicated in toxic epidermal necrolysis. These usually include, analgesics (NSAIDs), antibiotics – sulfonamides (sulfamethoxazole, sulfadiazine, sulfapyridine,

                                                                                                            beta-lactams (cephalosporins, penicillins, carbapenems) and anticonvulsants (Carbamazepine).

                                                                                                            Explanations

                                                                                                            • B. Systemic glucocorticoids may be used early in the treatment of this condition and are not a cause.
                                                                                                            • C. Aspirin is not linked to toxic epidermal necrolysis.
                                                                                                            • D. Hydrochlorothiazide diuretics are not associated with the production of toxic epidermal necrolysis.
                                                                                                            • Looking for all the podcast episodes?

                                                                                                              This FREE series is limited to every other episode, you can download and enjoy the complete audio series by joining The PANCE and PANRE Exam Academy.

                                                                                                              I will be releasing new episodes every few weeks. The Academy is discounted, so sign up now.

                                                                                                              Resources From The Show
                                                                                                              • CDC Guidelines for the pneumococcal vaccine
                                                                                                              • Join the PANCE and PANRE Academy + Smarty PANCE
                                                                                                              • My list of recommended PANCE and PANRE review books
                                                                                                              • The PANCE and PANRE Blueprint Checklist 
                                                                                                              • The Smarty PANCE NCCPA Content Blueprint Website + The PA Life Academy
                                                                                                              • USE CODE “PALIFE” TO GET 10% OFF THE RUTGERS PANCE AND PANRE REVIEW COURSE
                                                                                                              • This Podcast is also available on iTunes and Stitcher Radio for Android
                                                                                                                1. iTunes: The Audio PANCE AND PANRE Podcast iTunes
                                                                                                                2. Stitcher Radio: The Audio PANCE and PANRE Podcast Stitcher
                                                                                                                3. 17 min
                                                                                                                4. Episode 41: The Audio PANCE and PANRE Board Review Podcast

                                                                                                                  Welcome to episode 41 of the FREE Audio PANCE and PANRE Physician Assistant Board Review Podcast.

                                                                                                                  Join me as I cover 10 PANCE and PANRE board review questions from the Academy course content following the NCCPA™ content blueprint.

                                                                                                                  This week we will be taking a break from topic specific board review and covering 10 general board review questions.

                                                                                                                  Below you will find an interactive exam to complement the podcast.

                                                                                                                  I hope you enjoy this free audio component to the examination portion of this site. The full genitourinary board review includes over 72 GU specific questions and is available to all members of the PANCE and PANRE Academy.

                                                                                                                  • You can download and listen to past FREE episodes here, on iTunes or Stitcher Radio.
                                                                                                                  • You can listen to the latest episode, take an interactive quiz and download your results below.
                                                                                                                  • Listen Carefully Then Take The Quiz

                                                                                                                    If you can’t see the audio player click here to listen to the full episode.

                                                                                                                    Episode 41 PANCE and PANRE Podcast Quiz

                                                                                                                    1. A mother brings her 6-year-old boy for evaluation of school behavior problems. She says the teacher told her that the boy does not pay attention in class, that he gets up and runs around the room when the rest of the children are listening to a story, and that he seems to be easily distracted by events outside or in the hall. He refuses to remain in his seat during class, and occasionally sits under his desk or crawls around under a table. The teacher told the mother this behavior is interfering with the child’s ability to function in the classroom and to learn. The mother states that she has noticed some of these behaviors at home, including his inability to watch his favorite cartoon program all the way through. Which of the following is the most likely diagnosis?

                                                                                                                    1. Antisocial disorder
                                                                                                                    2. Dysthymic mood disorder
                                                                                                                    3. Obsessive-compulsive disorder
                                                                                                                    4. Attention deficit hyperactivity disorder
                                                                                                                    5. Click here to see the answer

                                                                                                                      Answer: D. Attention deficit hyperactivity disorder

                                                                                                                      Attention deficit hyperactivity disorder is characterized by inattention, including increased distractibility and difficulty sustaining attention; poor impulse control and decreased self-inhibitory capacity; and motor over activity and motor restlessness, which are pervasive and interfere with the individual’s ability to function under normal circumstances.

                                                                                                                      Explanations

                                                                                                                      • Antisocial behavior disorder is characterized by disregard for rights of others; a defect in the experience of compunction or remorse for harming others.
                                                                                                                      • Dysthymic mood disorder is characterized by chronic, sad mood occurring for at least 2 years in an adult (one year in a child). Behavioral problems are not part of this disorder.
                                                                                                                      • Obsessive-compulsive disorder is characterized by recurrent obsessions and compulsions that result in anxiety and disruptive behaviors related to those compulsions.
                                                                                                                      • 2. Which of the following is the treatment of choice for a torus (buckle) fracture involving the distal radius?

                                                                                                                        A. Open reduction and internal fixation

                                                                                                                        B. Ace wrap or anterior splinting
                                                                                                                        C. Closed reduction and casting
                                                                                                                        D. Corticosteroid injection followed by splinting

                                                                                                                        Click here to see the answer

                                                                                                                        Answer: B. Ace wrap or anterior splinting

                                                                                                                        A torus or buckle fracture occurs after a minor fall on the hand. These fractures are very stable and are not as painful as unstable fractures. They heal uneventfully in 3-4 weeks.

                                                                                                                        3. Which of the following can be used to treat chronic bacterial prostatitis?

                                                                                                                        A. Penicillin

                                                                                                                        B. Cephalexin (Keflex)
                                                                                                                        C. Nitrofurantoin (Macrobid)
                                                                                                                        D. Levofloxacin (Levaquin)

                                                                                                                        Click here to see the answer
                                                                                                                        Answer: D. Levofloxacin (Levaquin)

                                                                                                                        Chronic bacterial prostatitis (Type II prostatitis) can be difficult to treat and requires the use of fluoroquinolones or trimethoprim-sulfamethoxazole, both of which penetrate the prostate.

                                                                                                                        4. A 25 year-old male with history of syncope presents for evaluation. The patient admits to intermittent episodes of rapid heart beating that resolve spontaneously. 12 Lead EKG shows delta waves and a short PR interval. Which of the following is the treatment of choice in this patient?

                                                                                                                        A. Radiofrequency catheter ablation

                                                                                                                        B. Verapamil (Calan)
                                                                                                                        C. Percutaneous coronary intervention
                                                                                                                        D. Digoxin (Lanoxin)

                                                                                                                        Click here to see the answer

                                                                                                                        Answer: A. Radiofrequency catheter ablation

                                                                                                                        Radiofrequency catheter ablation is the treatment of choice on patients with accessory pathways, such as Wolff-Parkinson-White Syndrome.

                                                                                                                        Explanations

                                                                                                                        • Calcium channel blockers such as verapamil decrease refractoriness of the accessory pathway or increase that of the AV node leading to faster ventricular rates, therefore calcium channel blockers should be avoided in patients with WPW.
                                                                                                                        • Percutaneous coronary intervention is indicated in the treatment of coronary artery disease, not preexcitation syndromes.
                                                                                                                        • (Digoxin decreases refractoriness of the accessory pathway and increases that of the AV node leading to faster ventricular rates. It should therefore be avoided in patients with WPW.
                                                                                                                        • 5. Which of the following pathophysiological processes is associated with chronic bronchitis?

                                                                                                                          A. Destruction of the lung parenchyma

                                                                                                                          B. Mucous gland enlargement and goblet cell hyperplasia
                                                                                                                          C. Smooth muscle hypertrophy in the large airways
                                                                                                                          D. Increased mucus adhesion secondary to reduction in the salt and water content of the mucus

                                                                                                                          Click here to see the answer
                                                                                                                          Answer: B. Mucous gland enlargement and goblet cell hyperplasia

                                                                                                                          Chronic bronchitis results from the enlargement of mucous glands and goblet cell hypertrophy in the large airways.

                                                                                                                          Explanations

                                                                                                                          • Destruction of the gas-exchanging structures in the lung is characteristic of emphysema.
                                                                                                                          • There may be smooth muscle hypertrophy in chronic bronchitis but it is not to the extent as found in asthma and is not an underlying factor in the pathology of chronic bronchitis.
                                                                                                                          • Abnormal absorption of sodium and a reduced rate of chloride secretion in cystic fibrosis leads to thickening of the mucus and increase in adhesion of the mucus.
                                                                                                                          • 6. Which of the following dietary substances interact with monoamine oxidase-inhibitor antidepressant drugs?

                                                                                                                            A. Lysine

                                                                                                                            B. Glycine
                                                                                                                            C. Tyramine
                                                                                                                            D. Phenylalanine

                                                                                                                            Click here to see the answer

                                                                                                                            Answer: C. Tyramine

                                                                                                                            Monoamine oxidase inhibitors are associated with serious food/drug and drug/drug interactions. Patient must restrict intake of foods having a high tyramine content to avoid serious reactions. Tyramine is a precursor to norepinephrine.

                                                                                                                            Explanations

                                                                                                                            Lysine, glycine, and phenylalanine are not known to interact with MAO inhibitors.

                                                                                                                            7. Gallstones usually result in biliary symptoms by causing inflammation or obstruction following migration into the common bile duct or

                                                                                                                            A. cystic duct

                                                                                                                            B. pancreatic duct
                                                                                                                            C. duodenal ampulla
                                                                                                                            D. common hepatic duct

                                                                                                                            Click here to see the answer

                                                                                                                            Answer: A. cystic duct

                                                                                                                            Obstruction of the cystic duct by gallstones causes the typical symptom of biliary colic. Once obstructed the gallbladder distends and becomes edematous and inflamed. Gallstones can also migrate into the common bile duct through the cystic duct leading to a condition known as choledocholithiasis.

                                                                                                                            Explanations

                                                                                                                            • Obstruction of the pancreatic duct leads to development of acute pancreatitis.
                                                                                                                            • The duodenal ampulla is the area where the pancreatic duct and the common bile duct empty into the duodenum. Gallstones do not cause obstruction at this distal site.
                                                                                                                            • The common hepatic duct from the liver joins the cystic duct from the gallbladder to form the common bile duct. Stone migration occurs along the pathway of the cystic duct to the common bile duct, not along the common hepatic duct.
                                                                                                                            • 8. An elderly patient with poorly-controlled Type 2 diabetes and renal disease develops a fever of 102°F orally, productive cough, and dyspnea. Physical examination demonstrates a respiratory rate of 32/min, labored breathing, and rales at the left base. Pulse oximetry is 90%. Which of the following is the next appropriate step in the management of this patient?

                                                                                                                              A. Administer nebulized corticosteroids

                                                                                                                              B. Admit to the hospital
                                                                                                                              C. Oral antimicrobial therapy
                                                                                                                              D. Endotracheal intubation

                                                                                                                              Click here to see the answer

                                                                                                                              Answer: B. Admit to the hospital

                                                                                                                              Community acquired pneumonia is the most deadly infectious disease in the U.S. Important risk factors for increased morbidity and mortality include advanced age, alcoholism, comorbid medical conditions, altered mental status, respiratory rate greater than 30 breaths/min, hypotension, and a BUN greater than 30.

                                                                                                                              Explanations

                                                                                                                              • Inhaled corticosteroids are not utilized in the management of community-acquired pneumonia.
                                                                                                                              • Due to the age of the patient, comorbid diseases, and current signs of respiratory distress, intravenous not oral antimicrobial therapy is indicated.
                                                                                                                              • Endotracheal intubation is indicated for respiratory failure unresponsive to conservative management.
                                                                                                                              • 9. A 53 year-old female who is well known to the practice presents to the office complaining of increasing fatigue, constipation, and a weight gain of 10 lb (4.5 kg) over the past year. She also states others have noticed a recent hoarseness to her voice, and she is bothered by “charley horses” in her legs that wake her up at night. Her past medical history is unremarkable except for a history of hyperthyroidism treated by radioactive iodine 5 years ago. She is currently taking no medications and has no known drug allergies. Which of the following is the most likely cause of the patient’s symptoms?

                                                                                                                                A. Hypothyroidism

                                                                                                                                B. Hypoparathyroidism
                                                                                                                                C. Vocal cord paralysis
                                                                                                                                D. Radiation thyroiditis

                                                                                                                                Click here to see the answer
                                                                                                                                Answer: A. Hypothyroidism

                                                                                                                                The current symptoms, along with the past treatment of hyperthyroidism with radioactive iodine, would indicate hypothyroidism.

                                                                                                                                Explanations

                                                                                                                                • This is a possible later complication of subtotal thyroidectomy, not radioactive iodine therapy.
                                                                                                                                • This is an immediate complication of subtotal thyroidectomy or injury and does not occur with radioactive iodine therapy.
                                                                                                                                • Radiation thyroiditis may occur following radiation therapy but there is no history of the patient having previous external beam radiation therapy.
                                                                                                                                • 10. Which of the following is most frequently associated with bladder cancer?

                                                                                                                                  A. Hematuria

                                                                                                                                  B. Dysuria
                                                                                                                                  C. Urgency
                                                                                                                                  D. Frequency

                                                                                                                                  Click here to see the answer
                                                                                                                                  Answer: A. Hematuria

                                                                                                                                  Significant persistent hematuria >3 RBC/HPF on three urinalyses, a single urinalysis with >100 RBC, or gross hematuria, identifies significant renal or urologic lesions. Bladder cancer usually presents with painless hematuria.

                                                                                                                                  Explanations

                                                                                                                                  Dysuria, urgency, and frequency are associated with irritative voiding symptoms associated with cystitis.

                                                                                                                                  Looking for all the podcast episodes?

                                                                                                                                  This FREE series is limited to every other episode, you can download and enjoy the complete audio series by joining The PANCE and PANRE Exam Academy.

                                                                                                                                  I will be releasing new episodes every few weeks. The Academy is discounted, so sign up now.

                                                                                                                                  Get ReelDx at 40% off!

                                                                                                                                  I am so excited to be introducing ReelDx cases into my new SmartyPANCE board review website. This is a $99 value now included to all registered SmartyPANCE users. If you are just interested in access to the ReelDx cases through their website as a listener of this podcast you can get 40% off a one year subscription by entering the code “ThePALife” at checkout:

                                                                                                                                  • Follow this link for detailed instructions: Get ReeldDx at 40% off using code ThePALife
                                                                                                                                  • Resources From The Show

                                                                                                                                    • Join the PANCE and PANRE Academy
                                                                                                                                    • My list of recommended PANCE and PANRE review books
                                                                                                                                    • The PANCE and PANRE Blueprint Checklist 
                                                                                                                                    • The SmartyPANCE NCCPA Blueprint Website
                                                                                                                                    • USE CODE “PALIFE” TO GET 10% OFF THE RUTGERS PANCE AND PANRE REVIEW COURSE
                                                                                                                                    • This Podcast is also available on iTunes and Stitcher Radio for Android
                                                                                                                                      1. iTunes: The Audio PANCE AND PANRE Podcast iTunes
                                                                                                                                      2. Stitcher Radio: The Audio PANCE and PANRE Podcast Stitcher
                                                                                                                                      3. 16 min
                                                                                                                                      4. REPRODUCTIVE SYSTEM : THE AUDIO PANCE AND PANRE PODCAST TOPIC SPECIFIC REVIEW EPISODE 39

                                                                                                                                        Welcome to episode 39 of the FREE Audio PANCE and PANRE Physician Assistant Board Review Podcast.

                                                                                                                                        Join me as I continue to cover topic specific PANCE and PANRE review from the Academy course content following the NCCPA™ content blueprint.

                                                                                                                                        Click here to download my interactive content blueprint checklist

                                                                                                                                        This week we will be covering 10 topic specific OBGYN/reproductive board review questions.

                                                                                                                                        The reproductive system accounts for 8% of your PANCE/PANRE board exam.  

                                                                                                                                        Below you will find an interactive exam to complement the podcast.

                                                                                                                                        I hope you enjoy this free audio component to the examination portion of this site. The full reproductive review includes over 107 reproductive system content blueprint specific questions and is available to all members of the PANCE and PANRE Academy or my new site SMARTY PANCE!!

                                                                                                                                        • You can download and listen to past FREE episodes here, on iTunes, Google Play and Stitcher Radio.
                                                                                                                                        • You can listen to the latest episode, take an interactive quiz and download your results below.
                                                                                                                                        • Listen Carefully Then Take The Quiz

                                                                                                                                          If you can’t see the audio player click here to listen to the full episode.

                                                                                                                                          Reproductive System PANCE and PANRE Podcast Quiz

                                                                                                                                          You can take the interactive quiz by clicking here

                                                                                                                                          Looking for all the podcast episodes?

                                                                                                                                          This FREE series is limited to every other episode, you can download and enjoy the complete audio series by joining The PANCE and PANRE Exam Academy.

                                                                                                                                          I will be releasing new episodes every few weeks. The Academy is discounted, so sign up now.

                                                                                                                                          Resources and Show Notes:

                                                                                                                                          • Reproductive system PANCE and PANRE content blueprint course on Smarty PANCE
                                                                                                                                          • Reproductive System Contentent Blueprint 107 question exam on Smarty PANCE (members only)
                                                                                                                                          • Download my free interactive content blueprint checklist
                                                                                                                                          • My list of recommended PANCE and PANRE review books
                                                                                                                                          • USE CODE “PALIFE” TO GET 10% OFF THE RUTGERS PANCE AND PANRE REVIEW COURSE
                                                                                                                                          • This Podcast is also available on iTunes and Stitcher Radio for Android
                                                                                                                                            1. iTunes: The Audio PANCE AND PANRE Podcast iTunes
                                                                                                                                            2. Google Play: The Audio PANCE and PANRE Podcast Google Play
                                                                                                                                            3. Stitcher Radio: The Audio PANCE and PANRE Podcast Stitcher
                                                                                                                                            4. 14 min

                                                                                                                                            About The Audio PANCE and PANRE Physician Assistant Board Review Podcast

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                                                                                                                                            Multiple Choice Physician Assistant Board Review and Rotation Exam Questions on the Go – Listen and Learn

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