Puberty may seem like a chaotic phase of life, but the process is precisely controlled by a series of timed signals beginning in the brain. Before we are born, a set of neurons secreting GnRH (gonadotropin-releasing hormone) migrate to the brain and set up the hub that will control reproductive processes. During this time, these neurons recruit newborn astrocytes, and they stick together throughout life. In this episode, we speak with Dr. Vincent Prévot, Director of the Development and Plasticity of the Neuroendocrine Brain Team of INSERM, to discuss his research on the neuroendocrine regulators of reproduction. Dr Prévot tells us about how the GnRH neurons actively recruit astrocytes, and how this process can be interrupted. Listen to hear more about the processes that lead to puberty, environmental factors that affect the natural timing of puberty, and why it is important for puberty to happen at the “right time.” Additional music provided by Aaron Troutman.