The Gary Null Show

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Did Joe Biden Just Say That Out Loud (0:23)

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Why the economy really sucks (blame Goldman Sachs) (10:26)

Niall Ferguson – Woke Totalitarianism (0:19 to 18:14)

Just in case: Is Government the New God? – The Religion of Totalitarianism (13:27)

Taurine Supplementation Benefits Diabetes PatientsCapital Medical University (China), October 6, 2022

People with diabetes who received taurine supplements experienced improvements in glucose and other factors, according to the results of a review and meta-analysis of clinical trials, published in Food Chemistry: Molecular Sciences.Researchers analyzed five controlled trials including 209 participants, that evaluated the effects of taurine on individuals with type I or type II diabetes. Taurine doses ranged from 500 mg daily to 1,000 mg three times per day.Participants who received taurine had lower fasting blood glucose, hemoglobin A1c (HbA1c, a marker of long-term glucose control), and insulin resistance, compared to those given a placebo.“Taurine emerges as a new option for the management of patients with diabetes,” the scientists asserted.

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Vitamin D Deficiency Linked to Breast CancerAnkara Numune Research Oncology Clinic (Turkey), November 1, 2022

Most women with breast cancer were found to be deficient in vitamin D, according to the results of a study published in the journal Progress in Nutrition.Researchers analyzed the vitamin D status of 561 women, average age 55, with non-metastatic breast cancer.In this group, 81% of the women were deficient in vitamin D, and 11% had insufficient levels of the vitamin.Median 25-hydroxyvitamin D blood levels were only 13.91 ng/mL in this group of Turkish women.Optimal ranges by U.S. standards are 30-80 ng/mL. Life Extension’s minimal target for 25-hydroxyvitamin D is around 50 ng/mL.The researchers concluded that vitamin D levels should be measured in breast cancer patients and low levels should be corrected whenever diagnosed.

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Marijuana smokers show higher rates of emphysema, airway diseases than tobacco smokersUniversity of Ottawa (Ontario), November 15, 2022

Researchers from the University of Ottawa and The Ottawa Hospital have found marijuana smokers have a higher rate of emphysema and airway diseases compared to cigarette smokers.The findings, published in Radiology, examined the chest CT examinations of 56 marijuana smokers, 57 non-smokers and 33 tobacco-only smokers between 2005 and 2020. They determined higher rates of paraseptal emphysema and airway inflammatory changes, such as bronchiectasis, bronchial wall thickening, and mucoid impaction, in the marijuana smokers.”What’s unique about this study is that there hasn’t been anything comparing the imaging findings in tobacco smokers to marijuana smokers before. In fact, there is a lack of imaging research in marijuana, probably because it’s still illegal in many parts of the world, and in many U.S. states, which is why I think we were the first to do a project like this.” Despite the small sample size, Revah’s findings suggest that marijuana smokers saw additional effects on the lungs above tobacco alone, including more instances of large and small airways diseases.

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Morning physical activity is associated with the lowest risk of heart disease and strokeLeiden University Medical Centre (Netherlands), November 14, 2022

Morning physical activity is associated with the lowest risk of heart disease and stroke, according to a study in more than 85,000 individuals published today in the European Journal of Preventive Cardiology. The findings were consistent regardless of the total amount of daily activity.The study included 86,657 adults aged 42 to 78 years who were free of cardiovascular disease at baseline. The average age was 62 years and 58% were women. Participants wore an activity tracker on their wrist for seven consecutive days. During six to eight years of follow up, 2,911 participants developed c

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How Ukraine – Not Russia – Floods Social Media With War Propaganda (0:00 to 1:20)

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The Green New Deal’s Bad Science (8:14)

JUST IN: Matt Gaetz Says Kevin McCarthy Could Ask Democrats To Help Make Him Speaker Forbes Breaking News 1.35M subscribers Subscribe (5:19)

Neil Oliver asks why we should be expected to sweep Covid hysteria under the rug? (0:36 to 5:32)

Jimmy Dore – Tim Robbins Apologizes To Unvaccinated For Being Wrong On Covid Policy (0:00 to 9:13)

Grape Powder Could Extend Lifespan by 4-5 Years

Long Island University, November 3, 2022

In a study the authors called “remarkable,” researchers found that giving grape powder to mice reduced the risk of non-alcoholic fatty liver disease and extended lifespan.

To see if grape powder could modulate the harmful effects of a high-fat diet, researchers fed mice a typical Western (high-fat) diet. Half then received 5% standardized grape powder while the other half didn’t.

Compared to mice not fed the grape powder, the mice given grape powder saw beneficial increases in antioxidant genes, reductions in fatty liver, and extended lifespans.

The lead author estimated that when translated to humans, the extended lifespan would correspond to an additional 4-5 years in the life of a human.

The grape powder used in this study was composed of fresh red, green and black grapes that were freeze-dried to retain their bioactive compounds.

The researchers concluded: “These results suggest the potential of dietary grapes to modulate hepatic gene expression, prevent oxidative damage, induce fatty acid metabolism, ameliorate NAFLD (non-alcoholic fatty liver disease), and increase longevity when co-administered with a high-fat diet.”

Study: Neuroprotective Effect of Virgin Coconut Oil Helps Relieve ALS 

Katholieke University (Belgium), November 6, 2022  An animal study looked into the potential of coconut oil for preventing or reducing ALS symptoms.Coconut oil has already demonstrated safe efficacy for treating Alzheimer’s disease symptoms, which is also a neurodegenerative disease for which mainstream medicine has no answer. 1H-magnetic resonance spectroscopy is ideal for ALS treatment diagnostics and research. It is used for many animal and human studies to isolate minute molecular changes in brain and nervous system studies without having to procure tissue and blood samples. Thus, it is non-invasive.[The study results] revealed that the coconut oil supplementation together with the regular diet delayed disease symptoms, enhanced motor performance, and prolonged survival in the SOD1G93A mouse model. Furthermore, MRS data showed stable metabolic profile at day 120 in the coconut oil diet group compared to the group receiving a standard diet without coconut oil supplementation.  In addition, a positive correlation between survival and the neuronal marker NAA was found. … this is the first study that reports metabolic changes in the brainstem using in vivo MRS and effects of coconut oil supplementation as a prophylactic treatment in SOD1G93A mice.One of the major metabolites NAA (N-acetylaspartate), has been observed as an integral part of neuron loss, which is a major factor of onset ALS when it is diminished from the central nervous system.  NAA reduction was greater in the non-coconut oil fed group of rats, indicating those on coconut oil were experiencing less neurodegeneration and neuronal destruction.

Aerobic activity can reduce the risk of metastatic cancer by 72%

Tel Aviv University (Israel), November 14, 2022

A new study at Tel Aviv University found that aerobic exercise can reduce the risk of metastatic cancer by 72%. According to the researchers, intensity aerobic exercise increases the glucose (sugar) consumption of internal organs, thereby reducing the availability of energy to the tumor.

The study was led by two researchers from TAU’s Sackler Faculty of Medicine.

Prof. Levy and

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Asthma Can Be Reduced By Increasing Vitamin D Levels And Consuming Ginger

Tel Aviv University (Israel) & Columbia University, November 13, 2022According to research published in the journal Allergy, Dr Ronit Confino-Cohen and colleagues at Tel Aviv University analysed data from more than four million Israeli’s that are members of the nation’s largest healthcare provider — finding that of the 21,000 with asthma, those with a vitamin D deficiency were 25% more likely than other asthmatics to have had at least one flare-up in the recent past.

The effect of the vitamin is strongest in people with asthma and other lung diseases who are predisposed to respiratory infections. People with the worst vitamin D deficiency were 36 percent more likely to suffer respiratory infections than those with sufficient levels, according to research in Archives of Internal Medicine.

“Vitamin D has significant immunomodulatory effects and, as such, was believed to have an effect on asthma — an immunologically mediated disease,” said Confino-Cohen. “But most of the existing data regarding vitamin D and asthma came from the pediatric population and was inconsistent. Our present study is unique because the study population of young adults is very large and ‘uncontaminated’ by other diseases.”

Professor Catherine Hawrylowicz from King’s College London explained that findings already suggest that supplementation with vitamin D may one day be used not only to treat people who don’t respond to medications but also to reduce the doses of dangerous steroids in other asthma patients – thus reducing the risk of harmful side effects.

Of the 21,000 asthmatics studied, the team reported that those with vitamin D deficiency were at a higher risk of an asthma attack.

Meanwhile, a team of US-based researchers have suggested that ginger compounds could also be effective in reducing the symptoms of asthma.

The study, led by Elizabeth Townsend from Columbia University, investigated whether purified extracts of ginger that contained specific components of the spicy root could help enhance the relaxing effects of bronchodilators in asthmatic people.

The research team explained that they studied the effects of three separate components of ginger: 6-gingerol, 8-gingerol or 6-shogaol when exposed to airway smooth muscle (ASM) tissue samples that were caused to contract by exposing them to acetylcholine.

“We demonstrated that purified components of ginger can work synergistically with Beta-agonists to relax ASM,” said Townsend – adding that tissues treated with the combination of purified ginger components and isoproterenol showed significantly greater relaxation than those treated only with isoprotereno.

Indeed, one of the three ginger components, 6-shogaol appeared most effective in increasing the relaxing effects of the Beta-agonist.

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Natural matcha green tea extract found to effectively kill breast cancer cellsUniversity of Salford (UK), November 05, 2022

A recent study carried out by the University of Salford has found that one kind of green tea in particular, matcha, can kill breast cancer cells effectively.

The scientists at the university’s Biomedical Research Center used a process known as metabolism phenotyping on breast cancer stem cell lines. They discovered that matcha “shifted cancer cells towards a quiescent metabolic state” while stopping them from spreading. Best of all, this was achieved using a rather low concentration of just 0.2 mg/mL.

In addition, they discovered evidence that matcha affects the signaling pathways that promote cancer stem cells in a way that may make it a viable alternative to chemical cancer drugs like rapamycin.

The scientist explained that the tea essentially suppresses oxidative mitochondral metabolism, prevent

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Quercetin helps to reduce the risk of pancreatic cancerUniv. of Hawaii and Univ. of Southern California, November 1, 2022

Quercetin, which is found naturally in apples and onions, has been identified as one of the most beneficial flavonols in preventing and reducing the risk of pancreatic cancer. Although the overall risk was reduced among the study participants, smokers who consumed foods rich in flavonols had a significantly greater risk reduction.

This study, published in the American Journal of Epidemiology, is the first of its kind to evaluate the effect of flavonols – compounds found specifically in plants – on developing pancreatic cancer.

Researchers from the Univ. of Hawaii and Univ. of Southern California tracked food intake and health outcomes of 183,518 participants in the Multiethnic Cohort Study for eight years. The study evaluated the participants’ food consumption and calculated the intake of the three flavonols quercetin, kaempferol, and myricetin. The analyses determined that flavonol intake does have an impact on the risk for developing pancreatic cancer.

The most significant finding was among smokers. Smokers with the lowest intake of flavonols presented with the most pancreatic cancer. Smoking is an established risk factor for the often fatal pancreatic cancer, notes the research.

Among the other findings were that women had the highest intake of total flavonols and seventy percent of the flavonol intake came from quercetin, linked to apple and onion consumption.

It is believed that these compounds may have anticancer effects due to their ability to reduce oxidative stress and alter other cellular functions related to cancer development. Previously, the most consistent inverse association was found between flavonols, especially quercetin in apples and lung cancer, as pointed out in this study. No other epidemiological flavonol studies have included evaluation of pancreatic cancer.

While found in many plants, flavonols are found in high concentrations in apples, onions, tea, berries, kale, and broccoli. Quercetin is most plentiful in apples and onions.

Hops may help lower Alzheimer disease riskUniversity of Milano-Bicocca (Italy), November 9 2022.

Hops, the plant whose flowers are used to make beer, could have a future in the prevention of Alzheimer disease according to research reported in the journal ACS Chemical Neuroscience.

“The search for natural compounds, whose intake through diet can help prevent the main biochemical mechanisms responsible for Alzheimer disease onset, led us to screen hops,” Alessandro Palmioli of the University of Milano-Bicocca and colleagues wrote.

Acting on other positive findings for hops, the team identified feruloyl and p-coumaroylquinic acids, flavan-3-ol glycosides and procyanidins as compounds responsible for the plant’s neuroprotective action. These molecules interacted with amyloid-beta (a substance that forms sticky plaques in the brains of Alzheimer disease patients), to prevent it from forming fibrils and becoming toxic. Hops extracts were also found to prevent cell death by inhibiting oxidative stress and inducing autophagy, a process by which cells break down and destroy old or damaged proteins or other substances. The Tettnang variety of hops proved to be the most successful of the four varieties tested.

“The identification of natural compounds or natural mixtures, such as nutraceuticals, exploitable for the development of preventive strategies against Alzheimer disease (and other neurodegenerative diseases) appears as a better alternative to the treatment of symptoms, as the neuronal damage associated with the disease is irreversible,” the authors remarked. “Our results show that hop is a source of bioactive molecules with synergistic and multitarget activity against the early events underlying Alzheimer disease development. We can therefore think of i

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Antioxidants may reduce oxidative stress in men with prostate cancer

Universities of Connecticut, Louisiana State, North Carolina, South Carolina, and California , November 3, 2022

This latest paper – which looked at men with prostate cancer from the North Carolina-Louisiana Prostate Cancer Project – came in light of a growing body of evidence suggesting oxidative stress plays a role in the development and progression of prostate cancer. The researchers looked at biomarkers of oxidative stress in the blood, urine and prostate tissue. 

They found a greater antioxidant intake was associated with lower urinary 8-isoprostane concentrations. 

A 10% increase in antioxidant intake saw an unadjusted 1.1% decrease in urinary 8-isoprostane levels. 

8-Isoprostane has been described as a “reliable marker”  and recognised  “gold standard” for lipid peroxidation – the oxidative degradation of lipids. 

“This study demonstrated that intake of antioxidants was associated with less oxidative stress among men with incident prostate cancer,” the researchers concluded in the British Journal of Nutrition.   

“The results of this study and others warrant additional research in humans on the mechanisms underlying the relationship between dietary antioxidants and prostate tissue redox status and carcinogenesis, as well as determining whether this relationship may influence disease severity, progression and recurrence.” 

High-intensity exercise changes how muscle cells manage calcium 

Karolinska Institute (Sweden) November 2, 2022

Researchers at Karolinska Institutet in Sweden have discovered a cellular mechanism behind the surprising benefits of short, high-intensity interval exercise. Their findings, which are published in the scientific journal PNAS, also provide clues to why antioxidants undermine the effect of endurance training. 

A few minutes of high-intensity interval exercise is enough to produce an effect at least equivalent to that achieved with traditional much more time-consuming endurance training. High-intensity exercise has become popular with sportspeople and recreational joggers alike, as well as with patients with impaired muscle function. However, one question has so far remained unanswered: how can a few minutes’ high-intensity exercise be so effective?

To investigate what happens in muscle cells during high-intensity exercise, the researchers asked male recreational exercisers to do 30 seconds of maximum exertion cycling followed by four minutes of rest, and to repeat the procedure six times. They then took muscle tissue samples from their thighs.

“Our study shows that three minutes of high-intensity exercise breaks down calcium channels in the muscle cells,” says Professor Håkan Westerblad, principal investigator at Karolinska Institutet’s Department of Physiology and Pharmacology. “This causes a lasting change in how the cells handle calcium, and is an excellent signal for adaptation, such as the formation of new mitochondria.”

Mitochondria are like the cell’s power plants, and changes that stimulate the formation of new mitochondria increase muscle endurance. What the researchers found was that the breakdown of calcium channels that was triggered by the high-intensity exercise was caused by an increase in free radicals, which are very reactive and oxidise cellular proteins.

The cells therefore have antioxidative systems for trapping and neutralising the radicals. Antioxidants, like vitamins E and C, are also present in food and are common ingredients in dietary supplements. In the present study, the researchers examined what happens when isolated mouse muscles are treated

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Michael Moore’s Nonstop Lies & Gaslighting For Democrats – Jimmy Dore

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Study shows eating prunes daily can help prevent bone lossPenn State University, November 3, 2022

People often eat prunes to boost their digestive health, but a study published in the American Journal of Clinical Nutrition shows that consuming a handful of prunes a day may also help prevent bone loss when you are older.

Researchers from Penn State University reported that women in their 60s who consumed prunes had significantly less bone loss in their hips in a year compared to those who didn’t eat the dried fruits. This suggests that prunes can help reduce inflammation in the body, which is a key driver of bone loss.

The researchers recruited 235 women for the study. The volunteers had an average age of 62 and had already gone through menopause.

The participants were split into three equal groups:

One group didn’t consume prunes.Another group consumed at least 50 grams (g) of prunes a day, or four to six pieces daily.The last group consumed 100g of prunes, or 10 to 12 pieces daily.The volunteers ate the “Improved French” prune variety. All of their diet included calcium and vitamin D3 supplements, which can also help prevent bone loss.

The research team used scans to measure bone density in the hip, neck and hip socket at the start of the study, after six months and after one year. They found that the hips of the non-eaters had an estimated 1.1 percent loss of bone density a year after the study began.

Meanwhile, the bone density of those who consumed four to six prunes a day barely shifted.

The result was similar for the group that ate more prunes, but the researchers noted that any protective effect could be masked because of its much higher dropout rate.

Blood tests also showed that the women who consumed prunes had significantly lower inflammation levels than those who did not. There was no significant documented difference in bone mass in the spine or hip socket between the groups one year after the study began.

Tracing tomatoes’ health benefits to gut microbesOhio State University, November 7, 2022

Two weeks of eating a diet heavy in tomatoes increased the diversity of gut microbes and altered gut bacteria toward a more favorable profile in young pigs, researchers found.

After observing these results with a short-term intervention, the research team plans to progress to similar studies in people, looking for health-related links between tomatoes in the diet and changes to the human gut microbiome – the community of microorganisms living in the gastrointestinal tract.

“It’s possible that tomatoes impart benefits through their modulation of the gut microbiome,” said senior author Jessica Cooperstone, assistant professor at The Ohio State University.

The tomatoes used in the study were developed by Ohio State plant breeder, tand co-author David Francis, and are the type typically found in canned tomato products.

Ten recently weaned control pigs were fed a standard diet and 10 pigs were fed the standard diet fine-tuned so that 10% of the food consisted of a freeze-dried powder made from the tomatoes.

Fiber, sugar, protein, fat and calories were identical for both diets. The control and study pig populations lived separately, and researchers running the study minimized their time spent with the pigs – a series of precautions designed to ensure that any microbiome changes seen with the study diet could be attributed to chemical compounds in the tomatoes.

Results showed two main changes in the microbiomes of pigs fed the tomato-heavy diet – the diversity of microbe species in their guts increased, and the concentrati

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Zinc supplementation associated with higher levels of brain growth factorSoybean foods may protect menopausal women against osteoporosis Study finds diet high in saturated fat can reprogram immune cells in miceCoenzyme Q10 consumption reverses cholesterol transportStudy confirms that processed foods key to rising obesityViolence on TV: Effects from age 3 can stretch into the teen years

Zinc supplementation associated with higher levels of brain growth factor

Iran University of Medical Sciences, November 4 2022. 

A review and meta-analysis of randomized, controlled trials affirmed an association between supplementing with zinc and higher circulating levels of brain-derived neurotrophic factor (BDNF). Brain-derived neurotrophic factor plays a positive role in the survival of brain cells known as neurons. A reduction in BDNF expression occurs in Alzheimer and Parkinson diseases, multiple sclerosis and amyotrophic lateral sclerosis. Antidepressants and anthocyanin supplements have been shown to increase BDNF gene expression, and serum or plasma levels have been elevated by exercise and omega-3 fatty acid, resveratrol or zinc supplementation.

For their review and meta-analysis, Fahimeh Agh of Iran University of Medical Sciences and colleagues identified four trials that evaluated the effects of zinc supplements on serum or plasma BDNF levels among 185. Zinc dosages ranged from 25–30 milligrams per day given for 84–90 days. 

Pooled results of the trials found significantly higher BDNF levels among participants who received zinc compared with participants in the control groups. The increase in BDNF was significant at 30 milligram doses (which were used in 3 trials) and at all trial durations. Among the 3 trials that analyzed serum zinc levels, participants who were given zinc supplements had significantly increased zinc levels in comparison with the control participants. 

“A large body of evidence indicated BDNF as an important predictive factor for following the beginning, progress and cure of brain disorders due to its main role in brain neurogenesis and neuroplasticity,” Agh and her associates wrote. 

“Increased circulating levels of BDNF as a result of zinc supplementation suggest that zinc supplementation may be a safe and effective strategy to counteract neurodegenerative diseases that are correlated with low BDNF levels,” they concluded.

Soybean foods may protect menopausal women against osteoporosis 

University of Hull (UK), November 1, 2022

Eating a diet rich in both soy protein and isoflavones can protect menopausal women from bone weakening and osteoporosis, according to the results of a preliminary study presented today at the Society for Endocrinology annual conference in Edinburgh.

Soybean foods contain chemicals known as isoflavones that are similar in structure to oestrogen and so could theoretically protect women against osteoporosis by mimicking the action of oestrogen.

In this study, researchers from the University of Hull gave two hundred women in early menopause a daily supplement containing soy protein with 66mg of isoflavones or a supplement with soy protein alone for six months. The researchers investigated changes in the women’s bone activity by measuring certain proteins (βCTX and P1NP) in their blood. 

They found that the women on the soy diet with isoflavones had significantly lower levels of βCTX than the women on soy alone, suggesting that their rate of bone loss was slowing down and lowering their risk of developing osteoporosis. Women taking soy protein with isoflavones were also found to have decreased risk of cardiovascular disease than those taking soy alone.

“The 66 mg of isoflavone that we use in this study

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Study reveals the powerful pain-relieving properties of ashwagandha

Nizam Institute of Medical Science (India), October 30, 2022

People experiencing knee joint pain and discomfort, particularly those with knee osteoarthritis, may find relief in an Ayurvedic medicine called ashwagandha(Withania somnifera). A study published in the Journal of Ayurveda and Integrative Medicine found that the root and leaf extracts of ashwagandha relieve knee pain and discomfort caused by osteoarthritis.

In the search for safe and effective natural pain relief treatments, researchers from Nizam’s Institute of Medical Sciences (NIMS)  evaluated the efficacy and safety of the root and leaf extracts of ashwagandha in patients with knee joint pain and discomfort. Ashwagandha is known to contain analgesic, anti-inflammatory, and chondroprotective properties.

In the study, the researchers recruited 60 patients with knee joint pain and discomfort. These participants received placebo capsules, 125 milligrams (mg) of ashwagandha extract, or 250 mg of ashwagandha extract twice a day for 12 weeks.

The results revealed that participants who received doses of ashwagandha extracts experienced great reductions in pain, stiffness, and disability. Those who received the higher dose of ashwagandha, which was 250 mg, experienced even greater and faster effects than those who received the 125 mg dose. In addition, the ashwagandha treatment did not cause any side effect. Overall, both doses of ashwagandha extract caused significant reductions in pain, stiffness, and disability of patients in a dose-dependent manner without causing any side effect.Ashwagandha Root Supports Thyroid Hormone Levels

Sudbhawana Hospital (India), October 31, 2022

Eight weeks of supplementation with Ashwagandha root extract were associated with normalization of the thyroid stimulating hormones (TSH), serum thyroxine (T4) and serum triiodothyronine (T3) in people with elevated TSH levels.

“The results of the present study are in accordance with previous studies,” wrote the researchers in the Journal of Alternative and Complementary Medicine. “The results indicate a possible role for ashwagandha in regulating HPT axis. The anti-stress and cortisol-lowering effect of ashwagandha may provide a suitable explanation for the current outcome.”

Ashwagandha has been used traditionally as an adaptogen to rejuvenate health, maintain homeostasis, sustain normal thyroid function and maintain hormonal balance in human body. However, very few modern published papers have reported ashwagandha’s beneficial effects on thyroid function. This is the first clinical study that supports the traditional claim of ashwagandha as a thyroid modulator.

The new double blind, randomized, placebo-controlled study involved 50 people with elevated TSH levels. So called subclinical hypothyroidism is described as a thyroid disorder with no obvious symptoms of thyroid deficiency. Participants were randomly assigned to receive either ashwagandha supplements (600mg daily) or placebo for eight weeks.

Results showed that ashwagandha significantly improved serum TSH, serum T4 and serum T3 levels, achieving change toward normalization of 19%, 45% and 21% respectively.

“The outcome of the present study highlights the beneficial role of ashwagandha root extract for normalizing thyroid hormone levels in subclinical hypothyroid patients; however, further studies are required to elucidate the underlying mechanisms of ashwagandha,” concluded the researchers.

Enzyme in Broccoli, Cucumbers and Avocados Reverses Aging In Cells

Washington University School of Medicine

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Dietary supplement found to improve concentration levelsUniversity of Granada, November 3, 2022

The research group from the University of Granada (UGR) has tested the effects of a multi-ingredient dietary nootropic on concentration levels and cognitive performance. Nootropics are cognitive enhancers that have traditionally been used in the treatment of cognitive pathologies.

Leading this study was Lucas Jurado Fasoli—a researcher from the Scientific Unit of Excellence in Exercise, Nutrition and Health (UCEENS) at the Sport and Health Joint University Institute (iMUDS). He explains that, traditionally, nootropics have been drugs, with their corresponding side-effects.

“To address the issue of potential side-effects, different dietary nootropics have emerged as an alternative way to enhance cognitive performance. And these, as is the case in this study, are used by healthy individuals in activities such as preparing for competitive exams or video-game competitions,” explains Jurado Fasoli.

The results of the study showed that the acute intake of this multi-ingredient nootropic decreases the response time across different cognitive tests: in processing speed, inhibitory control, working memory, and cognitive flexibility. It also increases accuracy in tests involving processing speed, inhibitory control, and cognitive flexibility. The supplement contains L-tyrosine, acetyl L-carnitine, sodium citicoline, alpha-GPC, taurine, caffeine, mango leaf extract and huperzia serrata leaf.

These results were accompanied by an increase in positive emotions and a decrease in negative emotions and depression. And, importantly, the favorable effects of this nootropic did not appear to have any effect on the heart-rate of participants.

Previous studies have shown that supplementation with the combination of caffeine and taurine, L-theanine, tyrosine, and mango leaves extract can improve the RT in different cognitive and computerized tests. In this study, we showed that a dietary multi-ingredient nootropic improves the processing speed of information in young healthy adults. This effect could be due to the synergic effects of different dietary ingredients included in the nootropic. Also, it could be partially explained by the central nervous system activation and alertness enhancement effect of caffeine, which could increase the processing speed and decrease the RT. The inclusion of L-theanine as a dietary ingredient in the nootropic counteracts the potential effects derived from a high dose of caffeine on anxiety, psychological stress, blood pressure, and HR, which completely agrees with our results.

A sample comprising 26 young adults (50:50 male/female, with an average age of 25) participated in the study. They were required to undertake various cognitive tests twice, separated by 48 hours, having ingested either the multi-ingredient dietary nootropic or a placebo (randomized and triple-blinded across the sample).

Thirty minutes after ingestion, measurements were taken of processing speed, inhibitory control, working memory, cognitive flexibility, creativity, and verbal fluency. Different emotions were also evaluated and the participants’ heart-rate was recorded while they undertook the tests.

Consuming more magnesium associated with lower risk of mortality during years following heart attackWageningen University and Research (Netherlands), October 31, 2022

A study of people with a history of heart attack found that those who consumed more magnesium lived longer than those whose intake was low. Having a high magnesium intake, defined as greater than 320 milligrams (mg) per day, was associated with a 28% lower risk of dying from cardiovascular disease and a 22% lower risk of death from an

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Green tea and resveratrol reduce Alzheimer’s plaques in lab testsTufts University, November 2, 2022

Tufts researchers are working to understand what might slow progression of Alzheimer’s disease. They have tested 21 different compounds in Alzheimer’s-afflicted neural cells in the lab, measuring the compounds’ effect on the growth of sticky beta amyloid plaques. These plaques develop in the brains of people with Alzheimer’s.

The researchers found that two common compounds—green tea catechins and resveratrol, found in red wine and other foods—reduced the formation of plaques in those neural cells. And they did so with few or no side effects. The researchers reported their findings in the journal Free Radical Biology and Medicine.

Some of the 21 compounds tested reduced the disease progression by acting as anti-viral agents—slowing Alzheimer’s induced by the herpes virus. But finding a compound “that could diminish the plaques regardless of the virus component would be ideal, because that would show that regardless of the cause of Alzheimer’s, you might still see some kind of improvement,” says Dana Cairns, GBS12. Cairns is a research associate in the Kaplan Lab in the School of Engineering and led the research.

The initial screen found five compounds had “really robust prevention of these plaques,” she says. In addition to the green tea compounds and resveratrol, they found curcumin from turmeric, the diabetic medication Metformin, and a compound called citicoline prevented plaques from forming and did not have anti-viral effects.

“We hoped to find compounds that would be harmless and show some level of efficacy,” she said. Green tea compounds and resveratrol met that standard. “We got lucky that some of these showed some pretty strong efficacy,” Cairns said. “In the case of these compounds that passed the screening, they had virtually no plaques visible after about a week.”

The discovery is significant because there is no cure for Alzheimer’s or a way to prevent its progression, aside from several potential drugs developed by pharmaceutical companies that are still in trials, Cairns says. Compounds like these two that show some efficacy and are known to be safe and easily accessible could be taken as a supplement or consumed as part of one’s diet, she adds.

High fiber, yogurt diet associated with lower lung cancer riskVanderbilt University Medical School, October 28, 2022

A diet high in fiber and yogurt is associated with a reduced risk for lung cancer, according to a study by Vanderbilt University Medical Center researchers published in JAMA Oncology.

The benefits of a diet high in fiber and yogurt have already been established for cardiovascular disease and gastrointestinal cancer. The new findings based on an analysis of data from studies involving 1.4 million adults in the United States, Europe and Asia suggest this diet may also protect against lung cancer.

Participants were divided into five groups, according to the amount of fiber and yogurt they consumed. Those with the highest yogurt and fiber consumption had a 33% reduced lung cancer risk as compared to the group who did not consume yogurt and consumed the least amount of fiber.

“This inverse association was robust, consistently seen across current, past and never smokers, as well as men, women and individuals with different backgrounds,” she added. Shu said the health benefits may be rooted in their prebiotic (nondigestible food that promotes growth of beneficial microorganisms in the intestines) and probiotic properties. The properties may independently or synergistically modulate gut microbiota in a beneficial way.

Yoga Practice Beneficial to Patients With COPD

All India Institute of Medical Sciences Oct. 28, 2022

Patients with COPD