The Gary Null Show

Researchers identify molecule with anti-inflammatory properties in maple syrup

Midnight munchies mangle memory 

 

More Connectivity In The Brain Found In People Who Run

 

Singing found to support stroke rehabilitation

Violence spreads like a disease among adolescents, study finds

Vitamin D “sufficiency” is disease-dependent

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Omega-3 fatty acid intake linked to lower risk of premature mortality among diabetic men and women

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·         Your Ability To Balance On One Leg Reflects Your Brain Health

·         Actinidia arguta (sarunashi) juice found to inhibit lung cancer in mice

·         Overweight affects DNA methylation

·         Researchers find magnesium intake may be beneficial in preventing pancreatic cancer

Chris Hedges | Peace sacrificed for PROFIT  (8:01)

𝐌𝐚𝐫𝐢𝐚 𝐙𝐞𝐞𝐞 | 𝐖𝐞𝐚𝐥𝐭𝐡𝐲 𝐛𝐮𝐬𝐢𝐧𝐞𝐬𝐬𝐦𝐞𝐧 𝐫𝐞𝐪𝐮𝐢𝐫𝐞 𝐮𝐧𝐯𝐚𝐜𝐜𝐢𝐧𝐚𝐭𝐞𝐝 𝐜𝐫𝐞𝐰 𝐟𝐨𝐫 𝐭𝐡𝐞𝐢𝐫 𝐩𝐫𝐢𝐯𝐚𝐭𝐞 𝐣𝐞𝐭𝐬 (1:27)

The Disturbing Reality of Cobalt Mining for Rechargeable Batteries (5:00)

Study confirms the antitumor effects of pomegranate

Have you heard of magnolia bark? Studies have shown it to play a beneficial role in healthy sleep

Time spent in nature appears to slow Parkinson's, Alzheimer's

The joy of giving lasts longer than the joy of getting

Aging slowly turns the immune system into fat, study reveals

Curcumin Eases Post-Workout Muscle Soreness

Study links nutrients in blood to better brain connectivity, cognition in older adults

University of Illinois, December 20, 2022

A new study links higher levels of several key nutrients in the blood with more efficient brain connectivity and performance on cognitive tests in older adults. The study, reported in the journal NeuroImage, looked at 32 key nutrients in the Mediterranean diet, which previous research has shown is associated with better brain function in aging. It included 116 healthy adults 65-75 years of age. "We wanted to investigate whether diet and nutrition predict cognitive performance in healthy older adults," said University of Illinois postdoctoral researcher Christopher Zwilling, who led the study with U. of I. psychology professor Aron Barbey in the Beckman Institute for Advanced Science and Technology. The analysis linked specific patterns of a handful of nutrient biomarkers in the blood to better brain health and cognition. The nutrient patterns included omega-3 fatty acids, which are abundant in fish, walnuts and Brussels sprouts; omega-6 fatty acids, found in flaxseed, pumpkin seeds, pine nuts and pistachios; lycopene, a vivid red pigment in tomatoes, watermelon and a few other fruits and vegetables; alpha- and beta-carotenoids, which give sweet potatoes and carrots their characteristic orange color; and vitamins B and D. The researchers relied on some of the most rigorous methods available for examining nutrient intake and brain health, Barbey said. Rather than asking participants to answer food-intake surveys, which require the accurate recall of what and how much participants ate, the team looked for patterns of nutrient "biomarkers" in the blood. The team also used functional magnetic resonance imaging to carefully evaluate the efficiency with which various brain networks performed. The analysis found a robust link between higher levels of several nutrient biomarkers in the blood and enhanced performance on specific cognitive tests. These nutrients, which appeared to work synergistically, included omega-3 and omega-6 fatty acids, carotenoids, lycopene, riboflavin, folate, vitamin B12 and vitamin D. The analysis also revealed that a pattern of omega-3s, omega-6s and carotene was linked to better functional brain network efficiency. Different nutrient patterns appeared to moderate the efficiency in different brain networks. For example, higher levels of omega-3 fatty acids paralleled the positive relationship between a healthy frontoparietal network and general intelligence. The frontoparietal network supports the ability to focus attention and engage in goal-directed behavior. "Our study suggests that diet and nutrition moderate the association between network efficiency and cognitive performance," Barbey said. "This means that the strength of the association between functional brain network efficiency and cognitive performance is associated with the level of the nutrients."

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Sunlight offers surprise benefit -- it energizes infection fighting T cells

Georgetown University Medical Center, December 20, 2022

Sunlight allows us to make vitamin D, credited with healthier living, but a surprise research finding could reveal another powerful benefit of getting some sun. Georgetown University Medical Center researchers have found that sunlight, through a mechanism separate than vitamin D production, energizes T cells that play a central role in human immunity. Their findings, published in Scientific Reports, suggest how the skin, the body's largest organ, stays alert to the many microbes that can nest there. "We all know sunlight provides vitamin D, which is suggested to have an impact on immunity, among other things. But what we found is a completely separate role of sunlight on immunity," says the study's senior investigator, Gerard Ahern, PhD, associate professor in the Georgetown's Department of Pharmacology and Physiology. "Some of the roles attributed to vitamin D on immunity may be

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From the frontlines, the USEU/UK war on school playgrounds in Donbass. Eva Bartlett (6:58)

Mediterranean diet linked to lower preeclampsia risk

Cedars-Sinai Medical Center, December 22, 2022

In a new study evaluating the Mediterranean diet and adverse pregnancy outcomes, investigators from the Smidt Heart Institute at Cedars-Sinai found that women who conceived while adhering to the anti-inflammatory diet had a significantly lower risk of developing preeclampsia during pregnancy. The study, published in the peer-reviewed journal JAMA Network Open, also evaluated the association between the Mediterranean diet and other adverse pregnancy outcomes, including gestational diabetes and hypertension, preterm birth, delivery of a small-for-gestational-age infant, and stillbirth. “This multicenter, population-based study validates that a healthier eating pattern is associated with a lower risk of adverse pregnancy outcomes, the most exciting being a 28% lower risk for preeclampsia,” said Natalie Bello, MD, MPH, senior and corresponding author of the study and director of Hypertension Research in the Smidt Heart Institute. “Importantly, this connection between the Mediterranean diet and lower risk of adverse pregnancy outcomes was seen in a geographically, racially and ethnically diverse population.” Bello also notes that researchers found the association was stronger in women who are traditionally considered to be of advanced maternal age, those 35 or older. Preeclampsia is a serious blood pressure condition that develops during pregnancy and puts stress on the mother’s heart. Left untreated, the condition can cause serious complications like weakened kidney and liver function and decreased blood supply to the fetus. In addition to preeclampsia, the risk of gestational diabetes also decreased in women who more closely followed the heart-healthy diet. The study was part of the Nulliparous Pregnancy Outcomes Study: Monitoring Mothers-to-be, which enrolled 10,038 women . Of the women enrolled, 7,798 were included in the JAMA Network Open study. Women who were pregnant with their first child were asked to complete a semi-quantitative food frequency questionnaire during their first study visit, which occurred in the first trimester. The questionnaire focused on the women’s eating habits during the three months prior to their visit and asked the participants to report their intake of common foods and beverages. Individuals’ responses were then categorized into the nine components of a Mediterranean diet—vegetables, fruits, nuts, whole grains, legumes, fish, monounsaturated-to-saturated fat ratio, red and processed meats, and alcohol—to calculate a Mediterranean diet score. The data was compiled, analyzed and studied by researchers and showed: A high Mediterranean diet score was related to 21% lower odds of having any adverse pregnancy outcome, as well as a 28% and 37% lower risk of having preeclampsia/eclampsia and gestational diabetes.

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Almond findings continue to demonstrate prebiotic promise

University of Florida, December 17, 2022

Eating almonds is beneficial to maintaining a healthy gut microbiota composition and improving the diet quality of parents and children suggests a new study. The research is the first to monitor the effects of dietary change on digestive health and immune function in a parent and child and whether this positively affects immunity, inflammation and general health. Writing in Nutrition Research, researchers began by enrolling 29 healthy parent and child pairs in to a 14-week, randomised, controlled, crossover study. Parents and children consumed 1.5 and 0.5 ounces of almonds and/or almond butter, respectively, on a daily basis for three weeks, as part of t

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Mushroom compound level predicts cognitive function

jcvzNational University of Singapore, December 21 2022.

Findings from a study reported in Antioxidants revealed an association between lower plasma levels of ergothioneine (ET), a compound that occurs in mushrooms, and an increased risk of cognitive impairment and dementia.”Before this study, there was little evidence that ET levels in the blood can predict the risk of developing cognitive issues,” noted lead researcher Barry Halliwell, of the National University of Singapore Yong Loo Lin School of Medicine. “Our findings demonstrate that if your ET levels are low, your risk of developing cognitive problems increases.” The study included 470 men and women of an average age of 73. Magnetic resonance imaging (MRI) scans conducted at recruitment determined the presence of cerebrovascular disease and/or brain atrophy and blood samples were evaluated for plasma ergothioneine. Neuropsychological tests administered at the beginning of the study and during up to 5 years of follow-up evaluated cognitive function. At the beginning of the study, 189 study participants had dementia, 193 were cognitively impaired without dementia and 88 had no cognitive impairment. Men and women with low (below the median) ergothioneine levels had worse cognitive function in comparison with those who had high levels. While cognitive function decreased over time among those with low or high levels of ergothioneine, the rate of decline was greater among participants who had low ergothioneine levels. When examined according to cognitive status, the long-term associations occurred only in participants who did not have dementia at the beginning of the study. “This points to the possibility of using a simple blood test to detect ET levels for early screening in the elderly to identify those who may have higher risk of cognitive decline,” Dr Halliwell stated. The researchers are planning a trial to evaluate the effects of ergothioneine supplementation among adults with mild cognitive impairment.

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Acupressure versus acupuncture—which one is better at treating sleep disturbance in patients with cancer?

University of Hong Kong, December 21, 2022

Both acupuncture—which is invasive and involves inserted needles—and acupressure—which is non-invasive and involves mechanical pressure—can potentially help reduce sleep disturbance in patients with cancer. A recent analysis of published clinical trials suggests that acupressure may have a greater effect than acupuncture. The analysis, which is published in Worldviews on Evidence-Based Nursing, included 24 randomized controlled trials involving 2,002 patients. The findings suggest that nurses and other health professionals in oncology settings should be provided with acupressure training to help patients who are experiencing sleep problems.“Based on available evidence, acupressure may be a more promising approach than acupuncture for reducing sleep disturbance in patients with cancer,” said corresponding author Denise Shuk Ting Cheung, BNurs, PhD, RN, of the University of Hong Kong. “Future studies should focus on the differential mechanisms of action of acupressure and acupuncture and link them to the multifactorial causes of sleep disturbance in patients with cancer.”

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Extraversion, conscientiousness linked to immune system function

University of Nottingham, December 15, 2022

Researchers have long suggested that personality may influence health. Now, a new study suggests that certain personality traits may play a role in immune system function. The research team – led by Prof. Kavita Vedhara of the School of Medicine at the University of Nottingham in the UK – found that extraverts are more likely to have strong immune systems, while people who are conscientious tend

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Drinking hot tea every day linked to lower glaucoma risk

Brown University and UCLA, December 14, 2022

Drinking a cup of hot tea at least once a day may be linked to a significantly lower risk of developing the serious eye condition, glaucoma, finds a small study published online in the British Journal of Ophthalmology. The researchers looked at data from the National Health and Nutrition Examination Survey (NHANES) in the US. This is a nationally representative annual survey of around 10, 000 people that includes interviews, physical examinations, and blood samples, designed to gauge the health and nutritional status of US adults and children. In this particular year, it also included eye tests for glaucoma. Among the 1678 participants who had full eye test results, including photos, 84 (5%) adults had developed the condition. They were asked how often and how much they had drunk of caffeinated and decaffeinated drinks, including soft drinks and iced tea, over the preceding 12 months, using a validated questionnaire (Food Frequency). Compared with those who didn’t drink hot tea every day, those who did, had a lower glaucoma risk, the data showed. After taking account of potentially influential factors, such as diabetes and smoking, hot tea-drinkers were 74 per cent less likely to have glaucoma. But no such associations were found for coffee—caffeinated or decaffeinated—decaffeinated tea, iced tea or soft drinks. This is an observational study so no firm conclusions can be drawn about cause and effect, and the absolute numbers of those with glaucoma were small. Information on when glaucoma had been diagnosed was also unavailable. But tea contains antioxidants and anti-inflammatory and neuroprotective chemicals, which have been associated with a lowered risk of serious conditions, including heart disease, cancer, and diabetes, say the researchers.

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Effects of Resveratrol on Polycystic Ovary Syndrome: A Double-blind, Randomized, Placebo-controlled Trial.

Poznan University of Medical Sciences (Poland), November 29, 2022

Polycystic ovary syndrome (PCOS) is the most common endocrinopathy affecting women of reproductive age. Hyperandrogenism is the central feature of PCOS. Studies on isolated ovarian theca-interstitial cells suggest that resveratrol, a natural polyphenol, reduces androgen production. This study was designed to evaluate endocrine and metabolic effects of resveratrol on PCOS. This was a randomized (1:1) double-blind, placebo-controlled trial that evaluated the effects of resveratrol over a period of 3 months in an academic hospital. Resveratrol (1,500 mg p.o.) or placebo were administered daily. Primary outcome was the change in the serum total T. Resveratrol treatment led to a significant decrease of total T by 23.1% . In parallel, resveratrol induced a 22.2% decrease of dehydroepiandrosterone sulfate, a decrease of fasting insulin level by 31.8% and an increase of the Insulin Sensitivity Index (Matsuda and DeFronzo) by 66.3%. Levels of gonadotropins, the lipid profile as well as markers of inflammation and endothelial function were not significantly altered. Resveratrol significantly reduced ovarian and adrenal androgens. This effect may be, at least in part, related to an improvement of insulin sensitivity and a decline of insulin level.

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Encouraging risk-taking in children may reduce the prevalence of childhood anxiety

Macquarie University’s Centre for Emotional Health (Netherlands), December 13, 2022

A new international study suggests that parents who employ challenging parent behavioural (CPB) methods – active physical and verbal behaviours that encourage children to push their limits – are likely protecting their children from developing childhood anxiety disorders. Researchers from Macquarie University’s Centre for Emotional Health, along

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Turmeric studied for its ability to seek out and destroy cancer stem cells, the source of all tumors

Montclair State University, December 13, 202

Turmeric has gained immense popularity over the years not just for the unique flavor it adds to dishes like curries, but also for its various health benefits. One of its most promising therapeutic applications is as a natural remedy for cancer. Although the anticancer potential of turmeric isn’t new, a recent study published in Cancer Letters further proved the importance of this golden spice in understanding and treating cancer. The team of American researchers evaluated the ability of curcumin, which is a polyphenol in turmeric, to target cancer stem cells that are assumed to be the primary cause of cancer tumor formation and malignancy. Unlike conventional cancer models used in previous studies, the cancer stem cell model suggests that only a small population of cancer cells drive the initiation, maintenance, and growth of tumors. These stem cells regularly undergo renewal and differentiation into other cancer cells, which no longer have the ability to regenerate themselves. Therefore, in this model, cancer stem cells that are not killed by treatments lead to the formation of more invasive and treatment-resistant tumors. In this study, the researchers found that curcumin is more effective in eradicating cancer since unlike conventional treatments, this polyphenol also targets cancer stem cells. It can do so through various mechanisms of action, which include the following. Regulation of cancer stem cell self-renewal pathway — There are different pathways involved in the self-renewal of cancer stem cells. These include the Wnt/beta-catenin, sonic hedgehog 89 (SHH), and Notch pathways. The researchers found that curcumin can directly or indirectly interfere with these pathways in 12 different cancer cell lines Modulation of microRNA — The body contains microRNAs, which are short RNA sequences that don’t encode for anything. These microRNAs regulate more than 33 percent of protein-coding genes by targeting and binding to their corresponding messenger RNAs so that these won’t be expressed. In this study, the authors observed that curcumin altered microRNA expression in cancer stem cells so that they can’t produce everything that they need for tumor formation and growth. Direct anti-cancer activity — Curcumin selectively targets cancer cells and programs their death. When used in conjunction with conventional anticancer agents, this effect becomes more evident and the damage typically caused by chemotherapy is no longer observed. Overall, the results of this study show that for cancer treatments to be effective, they have to target and kill cancer stem cells just like turmeric does. Otherwise, these cancer stem cells will pave the way for the formation of more invasive and treatment-resistant tumors.

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Chiropractic spinal manipulation associated with reduction in low back surgeryUniversity Hospitals Cleveland Medical Center, December 19, 2022

A recent study from University Hospitals (UH) Connor Whole Health has found that adults who initially visit a chiropractor to receive spinal manipulation for low back pain caused by disc herniation or radiculopathy (i.e., sciatica) are less likely to undergo discectomy (i.e., disc surgery) over the subsequent two years. This study was recently published in the journal BMJ Open. In this retrospective cohort study, the authors selected adult patients, age 18 to 49, from a 101 million patient United States health records network (TriNetX, Cambridge, MA, U.S.). Patients with serious pathology or urgent indications for surgery were excluded from the study. Ultimately, the authors identified 5,785 patients who initially received chiropractic spinal manipulative th

Menopausal women should eat more blackcurrant to prevent bone lossUniversity of Connecticut, December 11, 2022

Hormonal changes are one of the leading causes of bone loss or osteoporosis. Menopausal women, in particular, are more likely to experience bone loss because they are deficient in estrogen, a hormone in women that protects the bones. The amount of estrogen drops when women reach menopause. To lower the risk of bone loss, researchers at the University of Connecticut suggested menopausal women should eat more blackcurrant. The researchers conducted an animal study to look at the effect of blackcurrant on bone mass in an estrogen-deficient mouse model. Earlier studies have reported that the anthocyanins in blackcurrant have antioxidant and anti-inflammatory properties that could potentially improve bone mass.For their study, which was published in the Journal of Medicinal Food, the team removed the ovaries of the mice to mimic estrogen deficiency in menopausal women. Then, they gave the mice either a basal diet alone or a basal diet that contains anthocyanin-rich blackcurrant extract. They measured bone mineral density, trabecular bone volume, and serum bone markers. Ovariectomy resulted in a significant reduction in bone mineral density and trabecular bone volume. However, the treatment of blackcurrant reduced ovariectomy-induced bone loss. In addition, the treatment decreased osteoclast-like cell formation and bone resorption activity. These outcomes suggest that blackcurrant may mitigate postmenopausal bone loss. Adequate estrogen level is important for maintaining the rhythm of bone remodeling. Since estrogen levels decline after menopause, this causes an imbalance in bone production and breakdown. Osteoclasts are cells that break down bone and are responsible for bone remodeling. With the decline of estrogen levels, osteoclasts become more active and break down more bone than it can form. With these findings, the researchers concluded that blackcurrant may help prevent bone loss in postmenopausal women. Improving your gut microbiome is also a way to prevent and reduce your risk of age-related bone loss. A study published in the Journal of Internal Medicine suggested that taking probiotic supplements daily can cut age-related bone loss by half. Researchers at the University of Gothenburg in Sweden gave elderly women a probiotic supplement to be taken twice a day for one year. The supplementation resulted in lower bone loss compared to those who did not take the supplement.

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Long-term antacid use linked to vitamin B12 deficiency

Kaiser Permanente in California, December 16, 2022

Antacids are commonly used to neutralize the acid in the stomach, helping many individuals who have acid reflux. But a new study suggests that using this medication consistently for 2 years or more is linked to a deficiency of vitamin B12, which can have adverse effects for the nervous system. The research, published in JAMA, is among the first to show associations between long-term exposure to antacids and vitamin B12 deficiencyin a large population-based study. The investigators say that antacids, including proton pump inhibitors (PPIs) and histamine 2 receptor antagonists (H2RAs), are some of the most commonly used pharmaceuticals in the US.However, because they suppress the creation of gastric acid, the team says antacids may lead to malabsorption of vitamin B12. This vitamin helps to keep the nervous system - consisting of the brain, nerves and spinal cord - healthy."Vitamin B12 deficiency is relatively common," say the researchers, "especially among older adults; it has potentially serious medical complications if undiagnosed." "Left untreated, vitamin B12 deficiency can lead to dementia, neurologic damage, anemia and other complications, which may be irreversible."The study found a link between 2 years' use of antacids or more and a deficiency of vitamin B12.Similarly, 4.2% of the vitamin-deficient patients had a 2-yea

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