The show opens with foreign correspondent Tony Five and top story: Harvard researcher studying dishonesty is (allegedly) dishonest. Dominique McKoy from University of Chicago's To&Through Project discusses what matters for high school and college success. Tony Five and David interview viral sensation Crazy Auntie Ann who discusses her videos rocking out and dispensing mental health advice. Sociologist Dalton Conley reveals whether DNA can predict your individual future and what that means for our collective future. (Check out Dalton's book The Social Genome here.) On Sex, Et Cetera, sexual health and consent educator Samantha Bitty and David answer the question: Is that normal?! Neuroscientist Dr. Yiren Ren shares her team's discovery of music's hidden power to reshape memory.

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The show opens with foreign correspondent Tony Five giving a dog update on Dony Dive's Dog Dilemma. Professor of organizations David Krackhardt shares how employees assigned more complex projects early in their work history had better career outcomes. Astronomer and University of Chicago professor Dr. Jacob Bean explains the current state of the alien life search on distant planets. Tony Five returns to the show for News You Can't Use with a morbid and very much (not) current story involving a window cleaner and a giant pencil. On Noah vs. The Unknown, Noah Cappe tells David what the Nazca lines in Peru are. Noah chats about thousands of strange holes in the ocean, and gives us a (somewhat confusing) window into dark matter and the fifth dimension. Dr. Yusuf Oc reveals that multiple-answer question format in exams improves students' learning. Finally, the world champion of spreadsheets Michael Jarman graces The Last Show with his presence.

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David talks about his cat (again) and covers top stories: Narco kitty apprehended; and Man arrested for vigilante spray-chalking a crosswalk. Foreign correspondent Tony Five talks about a dog-related dilemma he's having on Dony Dive's Dog Dilemma. (Explanation for terrible segment title: our comedy writers must be on vacation.) Tony and David take listener call (singular intended) from fan Lauren in Detroit. Emmy-winning city spokeswoman for Kansas City, Missouri Sherae Honeycutt goes over a letter she wrote to her younger self. Peter Quadrino discusses organizing a book club that has been reading the same enigmatic book for 12 years (and not being close to done). David plays a clip from the archive from when he was less than honest. Street performer Silver Elvis chats about a life busking as a silver... Elvis. Mike Shekhtman tells David the dos and don'ts of using generative AI during your job search.

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David and foreign correspondent Tony Five's top story for News You Can't Use: Firm posts lucrative office cat sitting job – Lisa Bond from the firm joins the show. Couples therapist Dr. Josh Novak goes over a study finding that couples who cuddle at bedtime feel more secure and less stressed. Tony Five rejoins the program to sing a jingle and discuss boundaries. On It's Time For Technology Time, Carmi Levy covers topics: Bankrupt DNA testing company 23andMe to be bought by Regeneron; Netflix will show generative AI ads midway through streams in 2026; China installs kill switches in solar panels sold to the West; and Google's AI Mode reportedly replacing iconic I'm feeling lucky button. Eva Buechel reveals that managers penalize employees for unplugging, even as they recognize its value. Writer and career coach Samuel Dunsiger explains why he quit his job and went back to school. Dr. Daniela Pirani and Dr. Vera Hoelscher reveal why women seldom propose to men – and what happens when they do.

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David's top stories: Chicago newspaper prints a fake summer reading list; and Woman sues adult websites after her son accesses them. Psychology researcher Dr. Owen Waddington reveals how a psychology experiment shows that children are more likely to delay gratification if a peer promises to wait too. David attempts to explain how ChatGPT works to foreign correspondent Tony Five. On News You Can't Use, Tony tells the tale of a man who is suing Whataburger for almost $1M over onions.  Coral from the Tomato Foster Club in New Orleans talks about running a dedicated rescue for orphaned neonatal and special needs kittens. David calls his brother Jon for his birthday. Therapist Gary Direnfeld joins the show for Therapy Thursdays on a Wednesday. David and Gary discuss making new friends as adults.

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David's top stories: A naked 5k run; and Jennifer Lopez sued for posting photos of herself. Foreign correspondent Tony Five and David receive Advice For Your Tomorrow's Self, Yesterday (AFY-TSY) dealing with sleep hygiene and spinal health. Psychological science researcher Dr. Mitch Brown explains when and why we choose physically strong leaders. Political scientist Dr. Paul Platzman shares his study revealing that diversity in your social circle may come with a surprising trade-off. Tony Five rejoins the broadcast just in time to interview sociolinguist Dr. Amanda Cole about Cockney rhyming slang. Comedian Natalie Norman and David discuss what people actually do when they travel. Dimana Atanassova explains that because people with psychopathic traits feel less pain, they assume you do too.

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The show opens with London-based foreign correspondent Tony Five reading a listener's texts. Tony's top story: British magic club rights a wrong. On Conspiracy Corner, Dr. Lee Kuhnle visats [sic] and goes over various papal conspiracies – past and present. (Check out Lee's podcast here.) Dr. Elisa Becker explains the difference between distaste and disgust, and what bacon and poop have in common. Psychology lecturer Dr. Jasmin Wertz shares how childhood maternal warmth predicts your key personality traits. Tony Five returns in time for caller Mike from Windsor to share his Advice For Your Tomorrow's Self, Yesterday (AFY-TSY). David gets angry when Mike's advice isn't really advice. Cancer epidemiologist Dr. Parveen Bhatti reveals that scrolling through screens at bedtime greatly increases your risk of insomnia. Atmospheric and oceanic sciences professor Brian Toon lists what would happen if WW3 broke out, and the safest countries to be in if it happens.

Call us at 1-888-505-6644 to give yourself advice from your yesterday's self for tomorrow!

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Foreign correspondent Tony Five revisits the Hertfordshire Harris hawk hero story from earlier in the week with the man himself, Steve Harris. Veterinarian Dr. Cliff Redford tells us about his docuseries, Dr. Cliff – Worldwide Vet. Jessica Reif shares her research showing that people who use AI at work are perceived as lazier and less competent. Dr. Natalie Pennington says those that actually call their romantic partner their best friend are in the minority. Carmi Levy joins the show for It's Time For Technology Time. David rants about video projectors to Carmi, and the two cover the following stories: A countertop robot that cooks your meals for you; Pope Leo XIV names AI one of the reasons for his papal name; and Company now hires back human help after going all-in on AI. Etiquette expert Nick Leighton and David discuss whether it's rude to recline while seated on an airplane. (Check out Nick's etiquette podcast Were you raised by wolves? here.) Dr. Dean Miller explains a social media trend called "grounding".

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David's top stories: WordPress CEO forces everyone to love pineapple on pizza; and Police find $600K in giant teddy bear during massage parlor raid. Entrepreneur Ramon van Meer reveals the sobering results from his test of customers paying more for American-made. On Conspiracy Corner, Nathan Radke gives an overview of the history of alien abductions and tells the Travis Walton story. (Check out Nathan's podcast here.) UK-based Foreign correspondent Tony Five gives us the latest provincial news. Sobriety coach Kelly France and David discuss addiction and sobriety. Dr. Jennifer Lansford explains that parental warmth – not poverty or danger – predicts positive world beliefs in adulthood.

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David tells foreign correspondent Tony Five about getting out of the wrong side of the bed. Tony talks about a criminal, "repeat offender" Swiss duck. Cognitive psychologist Dr. Arryn Robbins explains why AI images fool so many people. Psychiatry professor Dr. Eric Garland shares his study finding that mindfulness therapy reduces opioid craving and addiction. Brendan Case from Harvard's Human Flourishing Program illuminates how and when humans flourish with age. Then, it's Therapy Thursdays on a Wednesday with Gary Direnfeld. Gary and David discuss how to rebuild your life after trauma. Forensic criminology researcher Dr. Miranda Baumann shares how mental illness doesn't exactly explain who owns or carries firearms.

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