The Rounds Table

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This week, Amol and Rebecca discuss a recent study and an updated recommendation: A multi-centre, randomized control trial (the LEADER trial) examined the cardiovascular effect of liraglutide, a glucagon-like peptide-1 (GLP-1) analogue. Patients with type 2 diabetes and high cardiovascular risk were randomly assigned to receive either standard of care plus liraglutide or standard of ...

The post Motherhood Statements: Cardiovascular Effect of Liraglutide and Syphilis Screening appeared first on Healthy Debate.

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This week, Amol and Kieran discuss two studies: How can we prevent readmission? An observational study of 1000 general internal medicine patients from 12 United States academic medical centres found that 26.9% of readmissions were potentially preventable. Key factors associated with potential preventability included decision making in the emergency department, lack of information to outpatient ...

The post Pondering Preventability: Readmissions and Catheter-Associated UTI appeared first on Healthy Debate.

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This week Amol and Nathan discuss two studies: A multi-centre, prospective study evaluated the physical and mental health status of caregivers for patients discharged from the intensive care unit (ICU). Using hospital data and self-administered questionnaires, the study found most caregivers of critically ill patients are at high risk for depression, anxiety and poor mental health. ...

The post Exam Prep: Caregivers in the ICU and Symptoms in Smokers appeared first on Healthy Debate.

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This week, Amol talks about new antithrombotic therapy guidelines and using low calorie diet for diabetes remission. The American College of Chest Physicians issued new antithrombotic guidelines for the treatment of venous thromboembolism in February 2016. Amol highlights five updates in the guidelines, and discusses the evidence behind each recommendation. Diabetes has long been described ...

The post Spousal Input: New Antithrombotic Therapy Guidelines and Low Calorie Diet for Diabetes Remission appeared first on Healthy Debate.

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This week, Amol and Janice, staff internist at Mount Sinai Hospital, discuss two studies: A randomized trial asked whether diluted apple juice works just as well as oral rehydration therapy in treating minimal dehydration in children with gastroenteritis. Children 6 to 60 months presenting to the emergency department were randomized to half-strength apple juice or ...

The post New Territories: Apple Juice for Gastroenteritis in Children and Rheumatoid Arthritis Long Term Outcomes appeared first on Healthy Debate.

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This week, Amol and Dr. Kieran Quinn, both general internal medicine residents at the University of Toronto, discuss two studies: Where do people die? What types of care do they utilize at the end of life? A retrospective cohort study of people who died with cancer in seven developed countries evaluated the number of deaths ...

The post Valued Care: End of Life Care and Early Trends from “Choosing Wisely” appeared first on Healthy Debate.

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This week, we are replaying one of our favourite past episodes. Originally aired on February 12, 2016, Amol, general internal medicine resident at the University of Toronto, and Fahad, staff internist at St. Michael’s hospital in Toronto, discuss 3 papers: Where do physicians die? What is the intensity of the care they receive at the ...

The post Replay: How Physicians Die and Frozen Fecal Transplant for C. difficile appeared first on Healthy Debate.

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What is the risk of adverse events after a transient ischemic attack (TIA)? While older studies tell us that the risk of stroke or acute coronary syndrome after a TIA is high in the first 3 months, does this hold true today? An international TIA Registry tried to answer this question by characterizing TIA and ...

The post Talking TIAs: Physician Assisted Death in Canada and a Transient Ischemic Attack Registry appeared first on Healthy Debate.

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This week, Amol and Nathan discuss two high profile papers: Authors from the Centres for Disease Control and Prevention (CDC) recently published a report concluding that there is a causal relationship between Zika virus infection and a syndrome of birth defects, notably microcephaly. Nathan and Amol review the evidence the authors presented for this causality, ...

The post Blockbusters: Zika virus on birth defects and income on life expectancy appeared first on Healthy Debate.

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This week, Amol and Reena, internist at St. Michael’s hospital in Toronto, discuss the HOPE-3 trial. HOPE-3 is a 2-by-2 double blind randomized placebo controlled trial, which found that statins were effective in preventing cardiovascular events in intermediate risk patients but anti-hypertensives were not. While candesartan and hydrochlorothiazide were not superior to placebo, rosuvastatin resulted ...

The post A New HOPE: Statins and Anti-hypertensives in intermediate cardiovascular risk appeared first on Healthy Debate.