Think Neuro

One in ten Americans who are 65 and older suffer from Alzheimer’s dementia. It’s the 6th leading cause of death in the country, and it is a scourge worldwide. But little is known about what causes Alzheimer’s, and cures have been elusive. Dr. Verna Porter specializes in treating people with Alzheimer’s, and she remains optimistic. Until we have a remedy, she advises people to eat well and get plenty of sleep. Patients with Alzheimer’s often have abnormal levels of a gummy plaque called amyloid protein crowded around the neurons of the brain. No one knows for sure what causes it to accumulate. What we know for sure is that sleep clears toxins from the brain, amyloid protein among them. Yet, so few of us get enough of it. Eating a diet that’s low in sugar, and intermittent fasting, also may clear toxins. Even when we do invent a cure for Alzheimer’s, prevention will still be the best medicine, Dr. Porter says. Listen now for more on the mysterious origins of Alzheimer’s and what you can do to live with it if it strikes you or a relative.

For more information: pacificneuro.org | (310) 582-7640

Ashkan Mowla, MD, FAHA, FAAN, is neuro-interventional surgeon at the Pacific Neuroscience Institute® (PNI). He specializes in minimally invasive endovascular procedures to treat conditions and diseases of the brain and spine, including stroke, brain aneurysm, brain and spine arteriovenous malformation and fistula and carotid and intracranial disease.

He is triple board-certified neurologist with fellowship training in stroke and cerebrovascular diseases and also interventional neuroradiology. Prior to joining PNI, he was an assistant professor of neurological surgery at the Keck School of Medicine, University of Southern California (USC), Los Angeles, CA for 5 years.

Ryan Glatt turned his recovery from a traumatic brain injury into a passion for helping others restore and preserve the health of their brains. He now runs the Fit Brain Program at PNI, where he oversees a marvelous room, the Brain Gym. He leads people through workouts in which they move their bodies while exercising their minds, and where specialized brain-body exercise machines flash and beep. In addition to being the Fit Brain director, Ryan is also a brain health coach, which means that, he works as a specialized personal trainer for people who want to stave off cognitive decline. Ryan works in tandem with doctors at the institute, helping people manage their conditions, recover from surgeries, and maybe even preventing the need for future treatment. In today’s episode, Ryan Glatt takes us through his journey and tells us what brain health coaching entails. He also tells us the six vital things you can work on to help keep your brain (and body!) healthy, now and in the future.

Spinal deformity refers to abnormal curvatures of the spine, such as scoliosis, lordosis, and kyphosis. These conditions can arise from genetic defects, injuries, diseases like osteoporosis or arthritis, neuromuscular disorders, or poor posture. Symptoms range from visible misalignment to pain, weakness, loss of sensation, and in severe cases, paralysis or organ compression. Treatment options vary from observation, bracing, medications, and physical therapy to complex surgeries, with early diagnosis offering the best outcomes.

Marcus D. Mazur, MD, FAANS, is a board-certified fellowship-trained spine neurosurgeon. His clinical practice focuses on adult spinal surgery for disorders on the cervical, thoracic, and lumbar spine. He is a recognized expert in the treatment of adult spinal deformity, complex revision surgery, spinal oncology, and minimally invasive spine surgery. He also practices general neurosurgery.

Pseudotumor cerebri (PTC), also known as idiopathic intracranial hypertension, is a condition caused by elevated cerebrospinal fluid pressure in the brain. The symptoms of this condition mimic those of a brain tumor, giving it the name pseudotumor cerebri, meaning "false brain tumor." The increased pressure can cause swelling of the optic nerve and can result in loss of vision. Medications can often reduce the pressure and headache, but surgery is necessary in some cases.

Alexander M. Solomon, MD, is a neuro-ophthalmologist and strabismus surgeon at Pacific Neuroscience Institute in Santa Monica and Torrance, CA. Dr. Solomon’s personal philosophy is that each patient is individual and that diagnosis and optimal management of any disease is best carried out in conjunction with patient and family education, and understanding. His skillset includes visual field analysis and optical coherence tomography interpretation, as well as advanced adult strabismus diagnosis and treatment including thyroid eye disease, cranial nerve palsies, and orbital disease.

Marcus D. Mazur, MD, FAANS, is a board-certified fellowship-trained spine neurosurgeon. His clinical practice focuses on adult spinal surgery for disorders on the cervical, thoracic, and lumbar spine. He is a recognized expert in the treatment of adult spinal deformity, complex revision surgery, spinal oncology, and minimally invasive spine surgery. He also practices general neurosurgery.

Dr. Mazur completed his neurosurgery residency at the University of Utah and a postgraduate spine fellowship at the University of Virginia. Prior to joining PNI, he was a tenured faculty member at the University of Utah, where he was the program director of the neurosurgery residency and the director of the neurosurgery spine fellowship.

Dr. Daniel Kelly joins Dr. Stephen Sideroff this week on the Quantum Leadership Podcast.

In this powerful episode of the Quantum Leadership Podcast, Dr. Stephen Sideroff sits down with Dr. Dan Kelly, one of the nation’s leading neurosurgeons and co-founder and director of the Pacific Neuroscience Institute, for an illuminating look at the inner work, vision, and steady courage behind his remarkable leadership journey.

From leaving a secure tenured role at UCLA to create an entirely new model of neuroscience care, to performing high-stakes brain tumor surgeries where a millimeter can change a life, Dan shares what it truly takes to lead with clarity, presence, and heart. He reveals how risk-taking, disciplined innovation, and multidisciplinary collaboration helped him grow PNI from a small three-person nucleus into a nationally recognized institute with more than a dozen centers of excellence.

Dan also opens up about the personal side of leadership: coping with emotionally heavy diagnoses, maintaining balance through meditation and exercise, fostering trust in the operating room, and navigating the enormous pressures of a healthcare system while protecting what matters most: patient outcomes, team wellbeing, and integrity.

His story offers profound lessons for leaders facing uncertainty, complexity, or the need to build something groundbreaking from the ground up.

A meningioma is a type of tumor that arises from the meninges, which are the protective membranes that surround the brain and spinal cord. It is typically a slow-growing, usually benign tumor, derived from the cells of the arachnoid cap cells or the meningeal cells themselves. Meningiomas are the most common primary brain tumor. Fortunately, most are benign and slow-growing although up to 10% can grow rapidly. They are more common in women than men and can occur in all ages but are typically seen in middle-aged and older adults. Most meningiomas needing surgery can be removed through one of several minimally invasive keyhole approaches.

The Indomitable Dr. Howard Krauss
Guest podcast: Out of the Blindspot with Dr. Ore-ofe Adesina
Originally aired in 2 parts March 10 & April 21, 2025

Dr. Howard Krauss is a pioneering surgical Neuro-ophthalmologist specializing in minimally invasive orbital and oculoplastic surgery and adult strabismus. A leader in ophthalmology and medicine, he has blazed the trail for many who followed his footsteps into this specialty as surgeons. We’ll learn about his formative years including his journey from rocket scientist to neuro-ophthalmologist. We continue our conversation, learning about his experience training to become a surgical neuro-ophthalmologist, his experience as a co-founder of the Pacific Neuroscience Institute, and Dr. Krauss offers some of his thoughts on the current state of our healthcare system, and sage advice to the next generation of aspiring physicians and neuro-ophthalmologists.

Thyroid nodules are growths on your thyroid. They are usually benign (not cancer). They may become overactive and make too much of the thyroid hormone.

All types of hyperthyroidism are due to an overproduction of thyroid hormones. Hyperthyroidism (an overactive thyroid) causes your thyroid to make more thyroid hormone than your body needs. Hyperthyroidism can accelerate your body functions such as your metabolism (can cause unintentional weight loss) or a rapid or irregular heart rate.