This Week In Medicine

Hi, This Week in Medicine, we will be discussing recently published articles in Medical journals.

NEJM

Sarilumab for Relapse of Polymyalgia Rheumatica during Glucocorticoid Taper

Global Effect of Modifiable Risk Factors on Cardiovascular Disease and Mortality

Global Effect of Modifiable Risk Factors on Cardiovascular Disease and Mortality

Esketamine Nasal Spray versus Quetiapine for Treatment-Resistant Depression

JAMA

Effects of Cuff Size on the Accuracy of Blood Pressure ReadingsThe Cuff(SZ) Randomized Crossover Trial

Changes in the Use of Long-Term Medications Following Incident Dementia Diagnosis

Defining Usual Oral Temperature Ranges in Outpatients Using an Unsupervised Learning Algorithm

Annals of Internal Medicine

Association Between Vascular 18F-Fluorodeoxyglucose Uptake at Diagnosis and Change in Aortic Dimensions in Giant Cell Arteritis

Suspected Bronchiectasis and Mortality in Adults With a History of Smoking Who Have Normal and Impaired Lung Function

Nature Medicine

Pleconaril and ribavirin in new-onset type 1 diabetes: a phase 2 randomized trial

BMJ

Mortality risks associated with floods in 761 communities worldwide: time series study

Lancet

Camrelizumab plus rivoceranib versus sorafenib as first-line therapy for unresectable hepatocellular carcinoma (CARES-310): a randomised, open-label, international phase 3 study

Journal of Clinical Oncology

Phase II Trial of Atezolizumab Combined With Carboplatin and Pemetrexed for Patients With Advanced Nonsquamous Non–Small-Cell Lung Cancer With Untreated Brain Metastases

Hepatology

Etiological cure prevents further decompensation and mortality in patients with cirrhosis with ascites as the single first decompensating event

Blood

Real-world experience of CAR T-cell therapy in older patients with relapsed/refractory diffuse large B-cell lymphoma

Clinical Infectious Diseases

One Week of Oral Camostat Versus Placebo in Nonhospitalized Adults With Mild-to-Moderate Coronavirus Disease 2019: A Randomized Controlled Phase 2 Trial

Journal of infectious Diseases

Epidemiology and Risk Factors of Norovirus Infections Among Diarrhea Patients Admitted to Tertiary Care Hospitals in Bangladesh

Journal of Clinical Rheumatology 

Pan American League of Associations for Rheumatology Guidelines for the Treatment of Takayasu Arteritis

Arthritis and Rheumatology

The 2023 ACR/EULAR Antiphospholipid Syndrome Classification Criteria

Circulation

Changes in Cardiovascular Spending, Care Utilization, and Clinical Outcomes Associated With Participation in Bundled Payments for Care Improvement – Advanced

ACC

Home-Based Walking and Supervised Treadmill Exercise in PAD

Journal of Clinical Endocrinology & Metabolism

Diagnosis and Incidence of Congenital Combined Pituitary Hormone Deficiency in Denmark—A National Observational Study

Gram-Negative Bacteria and Lipopolysaccharides as Risk Factors for the Occurrence of Diabetic Foot

Neurology:

Randomized Phase II Study of the Safety and Efficacy of Semorinemab in Participants With Mild-to-Moderate Alzheimer Disease:

Chest

Redefining the Role of Bronchoscopy in the Workup of Severe Uncontrolled Asthma in the Era of Biologics

Emulating Target Trials Comparing Early and Delayed Intubation Strategies

Effectiveness of Flexible Bronchoscopy Simulation-Based Training

The American Journal of Respiratory and Critical Care Medicine

Circulating CC16 and Asthma: A Population-based, Multicohort Study from Early Childhood through Adult Life

Clinical Journal of American Society of Nephrology

Research and Nonresearch Industry Payments to Nephrologists in the United States between 2014 and 2021

Hi, This Week in Medicine, we will be discussing

NEJM

Ferric Carboxymaltose in Heart Failure with Iron Deficiency

JAMA

Comparison of Hospital Online Price and Telephone Price for Shoppable Services

Annals of Internal Medicine

Role of Artificial Intelligence in Colonoscopy Detection of Advanced Neoplasias

Nature Medicine

MDMA-assisted therapy for moderate to severe PTSD: a randomized, placebo-controlled phase 3 trial

BMJ

Preconception contraceptive use and miscarriage: prospective cohort study 

Lancet

Sex-related differences in functional capacity and its implications in risk stratification before major non-cardiac surgery

Journal of Clinical Oncology

Bladder-Sparing Treatment With Radical Dose Radiotherapy Is an Effective Alternative to Radical Cystectomy in Patients With Clinically Node-Positive Nonmetastatic Bladder Cancer

Clinical Infectious Diseases

Cholesterol Contributes to Risk, Severity, and Machine Learning-Driven Diagnosis of Lyme Disease 

Journal of infectious Diseases

Impact of HCV Testing and Treatment on HCV Transmission Among Men Who Have Sex With Men and Who Inject Drugs in San Francisco: A Modelling Analysis

Journal of Clinical Rheumatology 

Patterns of Involvement of the Hand Joints in Classical Rheumatoid Arthritis

Circulation

Biodegradable-Polymer or Durable-Polymer Stents in Patients at High Bleeding Risk: A Randomized, Open-Label Clinical Trial

ACC Latest in Cardiology

LDL-C Reduction With Lipid-Lowering Therapy for Primary Prevention of Major Vascular Events Among Older Individuals

Journal of Clinical Endocrinology & Metabolism

The Prevalence of Metabolically Unhealthy Normal Weight and Its Influence on the Risk of Diabetes

 Clinical Journal of Nephrology

Discrepancies between Cystatin C–Based and Creatinine-Based eGFR

Kidney international reports

Randomized Controlled Clinical Trial of the Effect of Treatment with Vitamin K2 on Vascular 

Hi, This Week in Medicine, we will be discussing

New England Journal of Medicine

Semaglutide in Patients with Heart Failure with Preserved Ejection Fraction and Obesity

Inhaled Fluticasone Furoate for Outpatient Treatment of Covid-19

Trial of Solanezumab in Preclinical Alzheimer’s Disease

JAMA

Two-Year Outcomes After Minimally Invasive Surfactant Therapy in Preterm Infants

Follow-Up of the OPTIMIST-A Randomized Clinical Trial

Annals of Internal Medicine

Comparative Safety Analysis of Oral Antipsychotics for In-Hospital Adverse Clinical Events in Older Adults After Major Surgery

A Nationwide Cohort Study

 The Effect of Low-Dose Glucocorticoids Over Two Years on Weight and Blood Pressure in Rheumatoid Arthritis: Individual Patient Data From Five Randomized Trials

 Nature Medicine

Longitudinal genomic surveillance of carriage and transmission of Clostridioides difficile in an intensive care unit

 British Medical Journal

Sensitivity, specificity, and diagnostic accuracy of WHO 2013 criteria for diagnosis of gestational diabetes mellitus in low risk early pregnancies: international, prospective, multicentre cohort study

Preconception contraceptive use and miscarriage: prospective cohort study

Objectives To evaluate the association between preconception contraceptive use and miscarriage.

Lancet

Effect of primaquine dose on the risk of recurrence in patients with uncomplicated Plasmodium vivax: a systematic review and individual patient data meta-analysis

 Clinical Infectious Diseases

Antiretroviral Therapy Intensification for Neurocognitive Impairment in Human Immunodeficiency Virus 

Journal of infectious Diseases

Bacterial Vaginosis and Spontaneous Clearance of Chlamydia trachomatis in the Longitudinal Study of Vaginal Flora

Journal of Clinical Rheumatology 

Disease-Modifying Antirheumatic Drug Use and Its Effect on Long-term Opioid Use in Patients With Rheumatoid Arthritis

 Circulation

Early Ablation for Atrial Fibrillation After Admission for Heart Failure

 Effect of Semaglutide 2.4 mg Once Weekly on Function and Symptoms in Subjects With Obesity-Related Heart FailureWith Preserved Ejection Fraction - STEP-HFpEF

 American Journal of Respiratory and Critical Care Medicine

FEV1/FVC Severity Stages for Chronic Obstructive Pulmonary Disease

 Mortality in Patients with Obesity and Acute Respiratory Distress Syndrome Receiving Extracorporeal Membrane Oxygenation: The Multicenter ECMObesity Study

Journal of Clinical Endocrinology & Metabolism

Efficacy and Safety of Low-dose Spironolactone for Chronic Kidney Disease in Type 2 Diabetes

Chloride and Potassium Assessment Is a Helpful Tool for Differential Diagnosis of Thiazide-Associated Hyponatremia

American journal of hypertension

Intensive Blood Pressure Control and Cardiovascular Outcomes in Elderly Patients: A Secondary Analysis of SPRINT Study Based on a 60-Year Age Cutoff

Semaglutide in Patients with Heart Failure with Preserved Ejection Fraction and Obesity

Inhaled Fluticasone Furoate for Outpatient Treatment of Covid-19

Trial of Solanezumab in Preclinical Alzheimer’s Disease

The Effect of Low-Dose Glucocorticoids Over Two Years on Weight and Blood Pressure in Rheumatoid Arthritis: Individual Patient Data From Five Randomized Trials

Association between physical therapy frequency and postacute care for a national cohort of patients hospitalized with pneumonia

Cancer Screening in the United States During the Second Year of the COVID-19 Pandemic

Albuterol-Budesonide Pressurized Metered Dose Inhaler in Patients With Mild-to-Moderate Asthma