Reports that at least 17 U.S. missionaries and their families have been kidnapped in Haiti. What we're learning this morning. Plus, a supply chain crisis, empty shelves and rising prices. President Biden calling on businesses to break the bottleneck. And an FDA panel recommends Johnson & Johnson boosters for a wide group, those 18 and older. Are they at greater risk? Now questions on mixing and matching vaccines. Dr. Anthony Fauci joins "This Week" co-anchor Martha Raddatz this morning.

After the Senate approved a debt ceiling increase through early December, George interviews Treasury Secretary Janet Yellen about the future of Pres. Biden’s agenda in Congress plus the September jobs report that missed expectations. Top Facebook executive Nick Clegg speaks for his first televised response amid calls for growing regulation of the tech giant. Amid the ongoing fallout from the subpoenas issued in the Jan. 6 probe, Jonathan Karl reveals new explosive reporting from his upcoming book “Betrayal: The Final Act of the Trump Show.” Plus, the Powerhouse round table.

As Pres. Biden pushes Democrats on Capitol Hill to end the stalemate on his signature infrastructure legislation, Jon Karl goes one-on-one with Senator Bernie Sanders on the state of negotiations as the party seeks unity. As the U.S. reaches the grim milestone of 700,000 lives lost to Covid, Jon Karl interviews Dr. Fauci on that new antiviral Covid pill from Merck and the continued divide over vaccine mandates. Plus, the Powerhouse Round table.

After pledging the House will vote on both the bipartisan infrastructure and the Democrats’ reconciliation packages, George goes one-on-one with Speaker Pelosi on the fate of Pres. Biden’s signature legislation. ABC Exclusive: After the CDC endorsed booster shots of the Pfizer vaccine for older and high-risk Americans, Pfizer Chairman and CEO Albert Bourla joins George to discuss the rollout plan plus vaccine authorization for children under 11. ABC Exclusive: In his first television interview, whistleblower and former top Trump DHS official Brian Murphy talks to George about DHS downplaying the threat of Russian election interference and white supremacist groups. Plus, the Powerhouse Round Table.

With an FDA advisory panel recommending Pfizer booster shots only for those over 65 or at high risk, Martha goes one-on-one with Dr. Anthony Fauci on the latest setback for the Biden administration in its booster plan push. After the Pentagon admitted a drone strike that killed 10 Afghan civilians was a mistake, Martha interviews Adm. Mike Mullen on the tragedy and Joint Chiefs Chairman Milley’s calls to China in the final months of the Trump presidency. Following a powerful day of testimony from U.S. gymnasts on the sexual abuse they suffered by team doctor Larry Nassar, Pierre Thomas and Christine Brennan join Martha to discuss the FBI’s failure in handling the case and what comes next.

After Pres. Biden announced a sweeping new vaccine mandate amid the delta variant, Surgeon General Vivek Murthy joins George to discuss how the administration plans to enforce the policy and the potential legal challenges from GOP governors. After calling for a pause in the Democrats' $3.5T economic package, George interviews Sen. Joe Manchin and goes one-on-one with Sen. Bernie Sanders on his strategy for passing the bill amid pushback from moderate Democrats. Plus the Powerhouse Roundtable.

Hurricane Ida devastated Louisiana and the northeast, causing flooding and killing dozens of people. ABC "This Week" anchor George Stephanopoulos goes one-one-one with White House Senior Advisor Cedric Richmond about what types of federal emergency assistance President Biden is prepared to authorize. The Supreme Court voted not to block a Texas law that would make it illegal to have an abortion after six weeks. Republican Senator Bill Cassidy spoke with George about the decision from the Supreme Court, and relief efforts in Louisiana. The nation will mark 20 years since 9/11 as the country absorbs more harrowing scenes from the chaotic exit out of Afghanistan, and George speaks with ABC's Martha Raddatz, Pierre Thomas, and retired ABC News broadcaster Charlie Gibson about that fateful day.

Collapse into chaos. The Biden administration is in damage control as the Taliban seizes power in Afghanistan, the military racing to evacuate Americans and our Afghan allies left behind. ABC "This Week" co-anchor Martha Raddatz sits down exclusively with US Defense Secretary Lloyd Austin, asking is the Pentagon was prepared -- and could the mission expand? Also, US Surgeon General Vivek Murthy has what you need to know about COVID-19 booster shots.

Following the deadly terror attack that killed 13 U.S. service members and an estimated 170 Afghans, Martha Raddatz interviews Secretary Blinken about the race to evacuate Americans and allies from Afghanistan before the August 31 deadline. Martha goes one-on-one with Senator Sasse about his call for the U.S. to maintain a “light footprint” in Afghanistan. With COVID hospitalizations passing 100,000 for the first time since January, Martha Raddatz goes one-on-one with Dr. Fauci. Plus, the power house roundtable.

With the Taliban gaining control of Afghanistan as the U.S. prepares for final withdrawal, Chief Washington Correspondent Jonathan Karl goes one-on-one with Secretary Antony Blinken and Wyoming Representative Liz Cheney. Karl speaks with Dr. Richard Besser on COVID-19. Plus, the Powerhouse Round table