Coma science is a rapidly evolving field. In this episode, expert panelists share how our understanding of coma and consciousness recovery is changing for patients with and without COVID-19. They also discuss how COVID-19 forced us to rethink and adapt sedation practices for critically ill patients and how this may have contributed to increasing delirium and disorders of consciousness. (Originally recorded July 15, 2021) Moderator: Neha Subhash Dangayach, MD, MSCR. Panelists: Brian L. Edlow, MD; Sherry H-Y. Chou, MD, MSc; and Casey Cable, MD, MSc. For more tools to help in the fight against COVID-19, visit CHEST’s COVID-19 Resource Center at chestnet.org/COVID19.