In this episode of NANNcast, 'Vaccines, Trust, and Tiny Immune Systems,' Dr. Aimee Bernard and Dr. David Higgins dive into practical strategies for discussing vaccines with families in the NICU, clinic and community, building trust with hesitant parents, and addressing common concerns about immunization schedules. They explore why the Hepatitis B vaccine is recommended at birth, how a baby’s immune system is equipped to handle multiple vaccines, and the difference between natural infection and the guided protection vaccines provide. The conversation also highlights trusted resources for families, tips for evaluating information, and the vital role neonatal nurses play in vaccine education and advocacy. Tune in for expert insights, science communication strategies, and actionable takeaways to support informed vaccine decisions.