Optimizing physical therapy for patients with severe cerebral palsy is discussed by the authors of two key papers highlighted by Editor Ann Van Sant in the latest edition of the podcast. Talking about one of the studies Jill Heathcock and Jennifer Christie report that intense daily PT yielded important outcome gains for two toddlers, while in another article Kim Lephart describes how a customized seating system brought benefits to a teenager. Stacey Dusing talks about the large developmental gains they noted from their program of care for premature infants transitioning from NICU to the home. Measuring lower extremity alignment and general flexibility in obese children is explored by Jennifer Tucker in her conversation with the podcast, Kristy Azbell talks about a multi-pronged, prolonged and successful intervention for an infant with arthrogryposis, and the Manual Ability Classification System is reported to be “fit for purpose” by Deepa Javanantham.