Pfizer chairman and CEO Albert Bourla sees cancer as the pharmaceutical company's next frontier. Meanwhile, funding and research in finding a cure for Alzheimer's might have crowded out more effective approaches. And, Bridgewater Associates founder Ray Dalio tells us how countries go broke.

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US President Donald Trump ramped up his tariff threats to the European Union while saying he would speak with the leaders of Canada and Mexico, as stock markets sank following a hectic weekend that saw prospects for a trade war turn into reality.
In remarks to reporters on Sunday night, Trump said he would hold separate calls on Monday morning with Canadian Prime Minister Justin Trudeau, as well as with the Mexican leadership, after announcing 25% tariffs on the US’s neighbors and top trading partners. The levies are set to take effect on Tuesday, barring a last-minute deal.
Bloomberg Daybreak hosts Nathan Hager and Karen Moskow bring you instant reaction to the weekend's developments on global trade.     

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This week, we look at where the Federal Reserve's 2% inflation target came from and how differently inflation is perceived across the country with the Fed presidents of New York, Minneapolis, and Chicago. Plus, we take you to two different office buildings in New York City, One Vanderbilt and 322 Eighth Avenue, to tell the story of the challenges that unite commercial real estate properties, regardless of class. And, Chinese AI startup DeepSeek roils global markets and the Magnificent 7.

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In this bonus episode from Bloomberg Daybreak, hosts Nathan Hager and Karen Moskow examine the emergence of DeepSeek. The Chinese artificial intelligence startup is rocking global technology stocks, raising questions over America’s technological dominance.   
Buzz grew over the weekend about DeepSeek’s latest AI model being cost-effective while running on less-advanced chips, casting doubt on the validity of the rich valuations for companies like Nvidia.   
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Just as mobile banking revolutionized our relationship with our money and led to a plethora of new tools for management and investing, the proliferation of crypto and blockchain technologies have opened up all manner of new investment opportunities that go far beyond what early Bitcoin adopters could’ve imagined.

This episode is sponsored by Coinbase.

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This week, we look at the future of insurance in Los Angeles after devastating wildfires, President Trump's economic argument for immigration enforcement, and the growing trend of non-alcoholic beer and spirits. We go to Davos for the annual World Economic Forum's gathering of business and world leaders as they face a more insular and less collaborative world.

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Bloomberg Washington Correspondents Joe Mathieu and Kailey Leinz deliver insight and analysis on the inauguration of President Donald Trump.

On this edition, Joe and Kailey speak with:

• Former-Trump Energy Secretary Dan Brouillette
• Lindsay Chervinsky, Executive Director of the George Washington Presidential Library
• Shirley Martey Hargis, nonresident fellow in the Atlantic Council’s Global China Hub
• Rep. Brad Sherman x RussellU.S. Representative for California's 32nd Congressional District
• United States Senator Bill Hagerty (R-TN)

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This week, we look at what the next Trump administration will do to deliver on its promises to make government smaller, negotiate more favorable trade deals, and sustain economic prosperity. We talk to BlackRock's Rick Rieder, Council on Foreign Relations' Michael Froman, PIMCO's Libby Cantrill, Apollo's Torsten Slok, and Committee for a Responsible Federal Budget's Maya MacGuineas.

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It’s been a rough week for UK assets. The pound fell to its lowest level in a year, gilt yields surged and investors are losing confidence in the government’s ability to control the nation’s deficit and high borrowing costs. Why are things spiraling now? Senior reporter Phil Aldrick joins this week’s In the City to explain. 

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This week, we follow Brian Moynihan's tenure of "responsible leadership" at Bank of America and the network of regional presidents he has developed. We look at the role of AI in feeding the growing need for healthier snacks, and the intersection of geopolitics and economic risks in the coming year.

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