The Most Important Question

What Can You Do With Just 493 Genes?


Listen Later

How did we get here?

That's today's big question, and today my guests are Roy Moger-Reischer, and our first three-time guest, Brandon Ogbunu.

Roy Moger-Reischer is a scientist trained in microbiology, evolution and data analysis for his PhD. He's currently a fermentation specialist Arzeda, working to develop new proteins and biochemistry for the production of valuable molecules.

Brandon Ogbunu, described as a radical collaborator, is an assistant professor in the Department of Ecology and Evolutionary Biology at Yale. His research takes place at the intersection of evolutionary biology, genetics, and epidemiology.

When I first read about the work of Roy and his lab compatriots to take this idea of a cell stripped down to only what is most essential -- a minimal cell -- and then to see if it would or could evolve to survive even basic mutations, my first thought was, "What?"

The answer, it turns out, is profound as hell.

And because I'm a self-aware moron, I also begged past guest, Brandon Ogbunu, to come back on the show to help me understand what the hell is happening here and what it means for our history, for society today, and for future breakthroughs to help answer the question:

What can you do with just 493 genes? And if the answer is not only survive, but thrive, what can we do once we know that about the building blocks of life?

-----------

Have feedback or questions? Tweet us, or send a message to [email protected]

New here? Get started with our fan favorite episodes at podcast.importantnotimportant.com.

-----------

INI Book Club:

  • The Ghost in the Shell by Shirow Masamune

  • The Dawn of Everything by David Graeber and David Wengrow

  • Find all of our guest recommendations at the INI Book Club: https://bookshop.org/lists/important-not-important-book-club

  • Links:

    • Read Roy's paper on the minimal cell

    • Keep up with Roy's work

    • Keep up with Brandon's work

    • Follow us:

      • Subscribe to our newsletter at importantnotimportant.com

      • Follow us on Twitter: twitter.com/ImportantNotImp

      • Subscribe to our YouTube channel

      • Follow Quinn: twitter.com/quinnemmett

      • Edited by Anthony Luciani

      • Produced by Willow Beck

      • Intro/outro by Tim Blane: timblane.com

      • Advertise with us: https://www.importantnotimportant.com/c/sponsors

        ...more
        View all episodesView all episodes
        Download on the App Store

        The Most Important QuestionBy Important, Not Important

        • 4.7
        • 4.7
        • 4.7
        • 4.7
        • 4.7

        4.7

        118 ratings


        More shows like The Most Important Question

        View all
        The New Yorker Radio Hour by WNYC Studios and The New Yorker

        The New Yorker Radio Hour

        6,811 Listeners

        On the Media by WNYC Studios

        On the Media

        9,201 Listeners

        The Gray Area with Sean Illing by Vox

        The Gray Area with Sean Illing

        10,743 Listeners

        Reveal by The Center for Investigative Reporting and PRX

        Reveal

        8,467 Listeners

        Living on Earth by World Media Foundation

        Living on Earth

        462 Listeners

        Pivot by New York Magazine

        Pivot

        9,654 Listeners

        This Week in Virology by Vincent Racaniello

        This Week in Virology

        2,057 Listeners

        Pod Save America by Pod Save America

        Pod Save America

        87,555 Listeners

        The Daily by The New York Times

        The Daily

        112,347 Listeners

        Lovett or Leave It by Lovett or Leave It

        Lovett or Leave It

        25,144 Listeners

        Today, Explained by Vox

        Today, Explained

        10,288 Listeners

        Consider This from NPR by NPR

        Consider This from NPR

        6,412 Listeners

        The Ezra Klein Show by New York Times Opinion

        The Ezra Klein Show

        16,327 Listeners

        On with Kara Swisher by Vox Media

        On with Kara Swisher

        3,530 Listeners

        Better Offline by Cool Zone Media and iHeartPodcasts

        Better Offline

        605 Listeners

        Not Right Now by Important, Not Important

        Not Right Now

        51 Listeners