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In this episode of the Causes or Cures Podcast, Dr Eeks speaks with Dr. Sam West, a researcher at the University of Oxford, about his study on what happens after people stop taking GLP 1 weight loss medications.

While much of the attention has focused on how these drugs work while people are taking them, this conversation looks at what happens when people stop. Dr West discusses how quickly weight tends to return (and how much), what happens to cardiometabolic markers after stopping treatment, and how these outcomes compare with weight regain after behavior-based interventions.

They also explore what these findings mean in practice, including long-term weight maintenance, patient expectations, and how insurers may weigh coverage for these medications. 

This episode offers important real world context for one of the most widely discussed drug classes in medicine today.

Dr. Sam West is a postdoctoral researcher with the Health Behaviours team based in the Department of Primary Care Health Sciences at the University of Oxford. He completed his PhD with the Nutritional Physiology Research Group at the University of Exeter, where his research centred around assessing how modulating dietary protein form influences postprandial skeletal muscle metabolism. His current research focuses on understanding how lifestyle (diet and exercise) and pharmaceutical interventions can be used in the treatment and management of obesity and type 2 diabetes.

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