As climate and ecological conditions shift across the United States, the geographic boundaries of several tick species are expanding—and with them comes growing confusion about the diseases they carry. In this episode, we explore the spread of the Lone Star tick (Amblyomma americanum) and the blacklegged tick (Ixodes scapularis), and how their overlapping ranges are complicating the diagnosis of tick-borne illnesses.

One of the biggest challenges is distinguishing between Lyme disease and STARI (Southern Tick–Associated Rash Illness). Both conditions can present with a similar bull’s-eye rash and early flu-like symptoms, yet they are caused by different organisms and may require different approaches to diagnosis and treatment.

Join us as we examine how shifting tick habitats, changing ecosystems, and evolving patterns of human exposure are reshaping what we thought we knew about tick-borne disease risk.