Welcome to Chain Reaction. 

A show that unpacks and dives deep into the latest trends, drama and news with some of the biggest names in crypto breaking things down block by block for the crypto curious. 

For this week’s episode, Jacquelyn interviewed Arianna Simpson, general partner at Andreessen Horowitz (commonly known as a16z). 

Prior to joining the a16z family, Arianna founded Autonomous Partners, an investment fund focused on crypto. She also helped launch Crystal Towers Capital, which is an early-stage fund investing primarily in YC companies. 

A16Z has dug deep into the crypto space after launching four funds dedicated to the industry, with the most recent one being about $4.5 billion in May 2022. Some of its portfolio companies include big crypto players we’ve interviewed in the past like Alchemy, Avalanche and Aptos.

We talked about Simpson’s background, how her strategy has changed over the years, what she looks for in founders and whether she would launch another VC firm in the future. 

And we also discussed:

• The current investing climate
• Web3 gaming space 
• Where founders are building 
• Regulatory landscape 
• Advice for founders 

Chain Reaction comes out every other Thursday at 12:00 p.m. PT, so be sure to subscribe to us on Apple Podcasts, Spotify or your favorite pod platform to keep up with the action.

The TechCrunch Podcast Network has been nominated for two Webbys in the Best Technology Podcast category. You can help TechCrunch win by voting for Chain Reaction, which digs into the wild world of crypto. Or Found which brings you the stories behind the startups by sitting down with the founders themselves. Please take a few moments to vote here. Voting closes April 20. (Obviously, I host Chain Reaction, so vote for my show!)

Chain Reaction comes out every Thursday at 12:00 p.m. ET, so be sure to subscribe to us on Apple Podcasts, Spotify or your favorite pod platform to keep up with the action.