If you’ve tried to get prescriptions filled in the last year or so, a pharmacist may have told you, “Sorry, we don’t have that drug right now.” That’s because there are some 323 active and ongoing drug shortages in the United States. That’s the highest number of such shortages since the American Society of Health System Pharmacists started tracking this data back in 2001.

These drug shortages touch every part of the healthcare system. Doctors are having to reconfigure their treatment plans due to short supply of certain drugs, like cancer treatments. And patients can be left going from pharmacy to pharmacy to get even the most common medications, like antibiotics.

SciFri’s John Dankosky talks with freelance journalist Indira Khera and journalist and physician Dr. Eli Cahan, who looked into why drug shortages happen, how they’re affecting the healthcare system, and what solutions are on the horizon.

Transcripts for each segment will be available after the show airs on sciencefriday.com.

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