Melinda French Gates has been through some painful and public transitions — ending her marriage of 27 years, stepping away from the foundation she built with her ex-husband Bill Gates and turning her professional focus to women’s health and social progress. She talks to Rachel about forgiveness, learning to trust, and her ex-husband’s association with Jeffrey Epstein. To listen sponsor-free and support the show, sign up for Wild Card+ at plus.npr.org/wildcard

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Oprah could never just ignore her weight. Everyone else was always talking about it – from tabloids to late-night shows. She talks to Rachel about her weight journey and her new embrace of GLP-1s, the topic of her new book, “Enough,” co-written with Dr. Ania Jastreboff. Oprah also opens up to Rachel about her childhood in Mississippi and the lessons she learned from Maya Angelou and Sidney Poitier.

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In her early 20s, Jennette McCurdy left her childhood acting career and turned to writing. In both her memoir, “I’m Glad My Mom Died,” and her debut novel, “Half His Age,” she confronts the kinds of abuse and power dynamics she had to navigate long before she was ready. But she tells Rachel she has been able to move past it and find acceptance on the other side. To listen sponsor-free and support the show, sign up for Wild Card+ at plus.npr.org/wildcard

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When Jonathan Goldstein sets out to help a guest on his podcast “Heavyweight,” he always hopes he can help them feel unburdened by the end. But it’s often on the path to finding closure for a regret or deep-seated disappointment that the real healing happens. Jonathan shares with Rachel what making the show has taught him and why he believes anyone is capable of change. 

Jamie Lee Curtis never wanted to be an actor. She tells Rachel, despite having famous show business parents, she originally thought she’d become a police officer. Jamie talks about how she unexpectedly wound up in Hollywood, her fight against unhealthy beauty standards in the industry, and why she thinks of her children’s books as “her best thing.” Jamie Lee Curtis is currently  in “Ella McCay.”

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