Dr. Dixon and Dr. Berezin discuss what policy makers can do regarding fentanyl and the evolving opioid epidemic, explore communication strategies to counter stigma and improve mental illness and substance use disorder policy, and document how the concept of multimorbidity is making its way into clinical practice. Articles may be viewed online at ps.psychiatryonline.org. We are conducting a listener survey. Please go to ps.psychiatryonline.org/podcast and select the link to the survey. It won’t take more than a few minutes to complete, and your feedback will remain anonymous. We appreciate your responses. Thank you.