As a practicing neurologist, Jonathan O' Keefe saw that his impact in clinical practice was linear — you see one patient, you impact one patient, patient number doubles, impact doubles, and you start again. Instead he wanted to combine his neurology and computer science background to impact deeper than he ever could using one discipline alone, by building a startup. Perfectly positioned to see the flaws in the system, and with the expertise to solve them, he set about building his company Machine Medicine, which has developed an AI platform for the objective measurement of disability from simple video clips.