From growing up on a dairy farm in western Victoria with 12 siblings to the frontlines of one of the toughest fights in medical research, Sam McGuane’s story is one of resilience, service, and hope. As the inaugural Chief Executive Officer of The Brain Cancer Centre, and a key leader behind Carrie’s Beanies for Brain Cancer, Sam is on a mission to transform the future of brain cancer research. 

In this heartfelt episode, Sam opens up about how the values of gratitude, service, and hard work, ingrained in him growing up on the farm, have shaped his approach to both business and charity. These lessons, learned early in life, now fuel his leadership as he works to change the future of brain cancer research. 

Brain cancer remains the leading cause of cancer-related deaths in children in Australia, with survival rates virtually unchanged for decades. Sam is determined to change that. He’s building a model that brings researchers together, fosters collaboration, and supports breakthroughs in treatment. The result? A research ecosystem focused on tangible progress, including one of the most significant brain cancer clinical trials in the world. 

We discuss: 

Sam’s story shows how small, everyday actions can lead to big change when fuelled by purpose and community. His mission is clear: No lives lost to brain cancer and he’s working tirelessly to make that a reality. 

To all our listeners, you may or may not know someone affected by brain cancer, but imagine making a choice today that could change someone's future forever. You have the power to be the hope someone needs. Whether it's donating, sharing this message, or getting involved in any way you can, every step brings us closer to a cure. 

To learn more about the incredible work Sam, Carrie, and their team are doing, and to contribute to this life-changing cause, visit Carrie’s Beanies 4 Brain Cancer and The Brain Cancer Centre. 

Sam, thank you for leading this vital cause with passion and purpose. 

Sincerely,