CKD-MBD can be a most confusing field. When we start learning about it, we are usually focused on lowering PTH levels, only to find out that in many scenarios high PTH levels are the consequence of PTH resistance and that overactivity of PTH might not even be the issue. But maybe PTH is not what we should be focusing on, maybe it’s phosphate and yet, how do we lower that efficiently? Treatment with vitamin D can lower PTH and increase phosphate. But at the end of the day, laboratory results might not be the main problem, maybe we should really focus on vascular calcifications? It’s complicated. We tried to untangle these dilemmas with Mathias Haarhaus, the current Chair of the CKD-MBD Working Group, in our new Podcast on CKD-MBD. Learn how to take care of your patients from someone with a lot of experience. It will certainly help.