Sathiya Sam discusses what to do when a good thing turns bad. He talks about the importance of understanding that humans seek solutions to existing painful problems and how sometimes the solutions we try may not work as expected. Sam presents two options when a solution doesn't work: trying it again or trying something different to accomplish the same goal. Sathiya Sam emphasizes that not all solutions work for everyone at all times and advises listeners to be patient and persistent in their search for the right solution.