We hear from a Mexican city in Sinaloa state where one of the big drug cartels is locked in its own civil war. Our correspondent Quentin Sommerville visited the state capital, Culiacán, where he witnessed scenes of brutal violence that have brought pain and terror to residents. Also: Cuba says its coastguard has killed four people on board a US-registered speedboat, in an exchange of fire off the Cuban coast. It said those on the boat were Cubans, living in the US, with a history of violent activity - and "terrorist" intentions. The American Secretary of State, Marco Rubio, called the shootout "highly unusual" and said the US would conduct its own investigation into the incident and not rely on the Cuban version of events. A British clinical trial on more than 500 people across 15 countries found that a new tablet to treat HIV - which combines two current treatments - is highly effective at keeping the virus suppressed. A BBC Eye investigation has revealed that Nepal’s top police officer gave the order allowing the use of live fire during last year’s deadly crackdown on Gen Z protests - one of the worst in the country's history. And the robot that conducted Denmark's National Symphony Orchestra. We have the verdict on its performance.

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