Alkaline Phosphatase (ALK PHOS) Lab Values

Objective: Determine the significance and clinical use of  alkaline phosphatase in clinical practice   Lab Test Name: Alkaline Phosphatase – ALP   Description: Measures amount of ALP in circulation Located in several places in the body: Liver Intestines Biliary tract Bones Placenta Different isoenzymes of ALP are used to determine: Liver, bone, intestine and other cancers Bone turnover in postmenopausal women   Indications: Evaluation of ALP: Hepatobiliary disease Malignancies Bone disease Bone damage in renal patients   Normal Therapeutic Values: Normal – 40-130 U/L Collection:  Plasma separator tube   What would cause increased levels? Increased levels assessed in: Liver disease Bone disease Pregnancy Amyloidosis Lung cancer Pancreatic cancer Congestive heart failure Ulcerative colitis Hodgkin’s disease Chronic renal failure Sarcoidosis   What would cause decreased levels? Hypophosphatasia (spelling error on existing outline on NURSING.com) Anemia Kwashiorkor Cretinism Hypothyroidism Zinc or magnesium deficiency Scurvy