The Podcast by KevinMD

Alzheimer's link with insulin resistance


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Nationally recognized psychiatrist, internist, and addiction medicine specialist Muhamad Aly Rifai discusses his article, "How insulin resistance may cause Alzheimer's disease." Muhamad introduces the paradigm-shifting concept of Alzheimer's as "Type 3 diabetes," arguing that insulin resistance in the brain is the root cause. He explains how this metabolic dysfunction starves neurons (especially in the memory-critical hippocampus), leading to the toxic beta-amyloid plaques and tau tangles associated with cognitive decline. Muhamad highlights the crucial link between diabetes and Alzheimer's risk and discusses breakthrough diagnostic tools (like new blood tests) that can identify the disease before memory loss begins. Discover the practical lifestyle and medical interventions (from diet to new diabetes medications) that may prevent, manage, or even reverse cognitive decline by treating its metabolic underpinnings.

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The Podcast by KevinMDBy Kevin Pho, MD

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