Co-Editor-in-Chief Millie Long, MD, MPH, FACG interviews Neena S. Abraham, MD, MSc (Epi), FACG of the Mayo Clinic on the newguideline "the Management of Anticoagulants and Antiplatelets During Acute Gastrointestinal Bleeding and the Periendoscopic Period," co-published between the American College of Gastroenterology and the Canadian Association of Gastroenterology. The authors also wrote a clinical practice guideline dissemination tool for practicing clinicians to understand the guideline through common scenarios encountered during endoscopic practice. (24:35)

Co-Editor-in-Chief Jasmohan Bajaj, MD, FACG and Douglas A. Simonetto, MD discuss the newly published article "Development of the AI-Cirrhosis-ECG Score: An Electrocardiogram-Based Deep Learning Model in Cirrhosis." This study aimed to develop a proof-of-concept deep learning-based artificial intelligence model that could detect cirrhosis-related signals on ECG and generate an AI-Cirrhosis-ECG, or ACE, score to correlate with disease severity. (12:59)

Co-Editor-in-Chief Jasmohan Bajaj and Dr Philip Katz of Weill Cornell Medicine discuss the recently published ACG Clinical Guideline for the Diagnosis and Management of Gastroesophageal Reflux Disease. First author Dr. Katz discusses how PPIs remain the medical treatment of choice for GERD even though multiple publications question potential adverse events. The guideline addresses key issues in PPI management and adverse events, so clinicians will have a comprehensive, go-to source in the guideline. (16:43)

Divyanshoo R. Kohli, MD of the Kansas City VA Medical Center in Missouri, discusses his publication of a retrospective analysis and comparison of outcomes of PEG and IRG using an integrated nationwide database. (19:29)

Co-Editor-in-Chief Brennan Spiegel, MD, MSHS, FACG interviews Arnold Wald, MD, MACG to discuss highlights from the ACG Clinical Guideline Management of Benign Anorectal Disorders, published in the October 2021 issue of the American Journal of Gastroenterology. Download slides summarizing key concepts and treatment recommendations for proctalgia syndromes, chronic anal fissures, and hemorrhoids to follow along with this podcast. (31:18)

Binu V. John, MD, MPH joins Co-Editor-in-Chief Brian Lacy, MD, PhD, FACG to discuss the retrospective study conducted through the US Veterans Administration which examined the association of ursodeoxycholic acid liver-related death, hepatic decompensation, and hepatocellular carcinoma in patients with primary biliary cirrhosis. (23:28)

Co-Editor-in-Chief Brennan Spiegel, MD, MSHS, FACG interviews his Co-Editor-in-Chief Brian Lacy, MD, PhD, FACG on the recent Red Section article "Controversies in Gastroparesis: Discussing the Sticky Points." Listen for a discussion on the 10 controversies in gastroparesis, including the uncommonness of abdominal pain in patients with gastroparesis, endoscopic pyloric therapy, and timing of emptying during scans that could lead to an incorrect diagnosis. (22:56)

Ira Jacobson, MD, FACG joins Co-Editor-in-Chief Brian Lacy to discuss the recently published article on the clinical features and prognostic implication of cholangiopathy after severe COVID-19. (29:49)

Colleen Kelly, MD, FACG joins Co-Editor-in-Chief Brian Lacy, MD, PhD, FACG to discuss the preferred approach to the management of adults with C. difficile infection taken from the ACG Clinical Guideline. (21:48)

Shanti Eswaran, MD and Co-Editor-in-Chief Brennan Spiegel, MD discuss the new study on how kiwifruit can improve symptoms in patients with chronic constipation. (15:58)