If the past year has shown us anything, it’s that GLP-1s are here to stay. But as time passes, we’re also learning more about them — from new uses to new side effects to unexpected cultural trends. So have these drugs really lived up to the promise of easy weight loss?

On this episode of Health Matters, Mayo Clinic dietitian Tara Schmidt rejoins us — one year after our original GLP-1 episode — to talk about what we’ve learned so far, what’s surprised researchers and patients, and what questions still need answers.