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Part 3 of 4: Jon Chee hosts Barry Ticho, Founder of Verve Therapeutics and Chief Medical Officer at Stoke Therapeutics, a biotech company addressing the underlying cause of severe diseases by upregulating protein expression with RNA-based medicines.
With an MD PhD from the University of Chicago and extensive experience across academia and industry, Barry brings over two decades of expertise in clinical development. His journey includes roles as Head of Development at Moderna, Head of External R&D Innovation at Pfizer, and VP of Clinical Development at Biogen, where he's been instrumental in advancing numerous therapeutic programs across multiple disease areas.
Barry's unique perspective spanning academic medicine and biotechnology innovation makes his insights invaluable for aspiring leaders in the field.
Join us this week to hear about:- Barry’s switch from academia to industry, and the challenges of his role at Merck
- Navigating drug development and the rigorous standards of pharmaceutical research
- Leading patient-centered clinical development at Biogen to create impactful therapies
- Exploring the potential of RNA medicine at Pfizer and Moderna
- Working on Moderna’s lipid nanoparticle technology, the basis for the COVID-19 vaccine
Please enjoy Jon’s conversation with Barry Ticho.
Subscribe to the podcast: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994
Find Our Guest, Barry Ticho, at these links:Â https://www.linkedin.com/in/barryticho/Â https://www.stoketherapeutics.com/Â https://www.vervetherapeutics.com/Â
Find Our Host, Jon Chee, at these links:Â https://www.linkedin.com/in/joncheehttps://www.excedr.com
Excedr Socials & WebsiteLinkedIn: https://www.linkedin.com/company/excedr/ Youtube: https://www.youtube.com/@excedr Instagram: https://www.instagram.com/excedr_inc Twitter: https://twitter.com/ExcedrInc Facebook: https://www.facebook.com/excedr TikTok: https://www.tiktok.com/@excedr Podcast Website: https://www.thebiotechstartupspodcast.com/Â
Topics Mentioned:Merck: https://www.merck.com/Â Biogen: https://www.biogen.com/Â Pfizer: https://www.pfizer.com/Â Wave Biosciences: https://wavelifesciences.com/Â Moderna: https://www.modernatx.com/en-USÂ Verve Therapeutics: https://www.vervetx.com/Â
People Mentioned:StĂ©phane Bancel: https://www.linkedin.com/in/st%C3%A9phane-bancel-8185251Â
Timestamps:00:00 Intro02:06 Transitioning from academia to Merck03:41 Rigorous drug development processes at Merck06:00 Industry vs. academia: reproducibility and research quality in pharma08:35 Patient-centered clinical trials at Biogen09:45 Phases of clinical trials and ensuring patient access14:06 Challenges in drug approval: biology, regulations, and precision medicine18:24 Biogen’s focus on impactful therapies for severe diseases23:14 Joining Pfizer for cardiovascular research and RNA exploration27:04 Exploring RNA therapeutics at Pfizer and transitioning to Moderna30:21 Driving lipid nanoparticle breakthroughs at Moderna36:23 OutroThe Biotech Startups Podcast gives you a front-row seat to the business
and science of building a biotech. Hosted by Jon Chee, CEO of Excedr, the show features honest conversations with founders, execs, and investors about their work, their companies, and how they got there. From scientific breakthroughs to startup lessons, each episode explores what it really takes to grow a life science company—from pre-seed to IPO.
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