What is the biggest game of the 2025 season for the South Carolina Gamecocks? Clemson is the obvious choice, but Chris Marler explains why the answer is the fourth game of the season against the Missouri. We dive into the 2025 schedule and talk about the must win games and potential losses. We also discuss the four games that ESPN labeled as the most impactful and important games for Shane Beamer, LaNorris Sellers, and the rest of the 2025 Gamecock football team as well.