The ACC and AHA just dropped a massive 123-page clinical practice guideline on the management of dyslipidemia, fundamentally shifting how we approach cardiovascular risk in primary care. From retiring the pooled cohort equations in favor of the PREVENT calculator to introducing the CPR framework and establishing hard numerical targets for LDL and ApoB, there is a lot to unpack. I went through the entire document so you don't have to.

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CHAPTERS:
00:00 - Intro
01:39 - The Four Main Steps of the Guidelines
02:16 - Retiring the Pooled Cohort Equations
02:28 - The PREVENT Calculator & Risk Thresholds
04:52 - Net Clinical Benefit: NNT vs. NNH
07:46 - The CPR Framework for Personalized Care
09:23 - Moving Beyond LDL to ApoB
11:22 - Understanding Lp(a)
13:52 - Coronary Artery Calcium (CAC) Scores
15:31 - The Return of Hard Treatment Targets
17:44 - The Expanded Lipid-Lowering Toolkit
20:04 - Lifestyle and Diet Recommendations
20:51 - The Primary Care Algorithm

SELECTED REFERENCES:
https://www.ahajournals.org/doi/10.1161/CIR.0000000000001423

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