Bob gets to chat with a couple of couples in this episode! First up, Bob calls up Grant and Excel (who is VERY excited to chat with Bob) to chat about her fears of Covid while trying to manage her diabetes medication and cries to Bob about how he (and Danny Tanner) acted as a father to her while hers was a way. Later, Bob talks to a couple in Florida whose wife is a social worker, employed at a hospice. This episode also may involve a very amusing story about a woman in hospice who only could be comforted by watching Fifty Shades of Grey.

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Bob wants to make sure you're taking care of yourself. Making sure that you're stocked up on toilet paper, but honestly, not too stocked because what are you doing with all of that? So he picks up the phone to discuss life with a few callers. One caller talks about how their grandfather thought he had the virus and the fear surrounding that uncertainty. Later, Bob gets serenaded with his own rendition of "My Dog Licked My Balls." Plus, Bob discusses the life of a caller whose mom works with the health department, as well as a woman who discusses her experiences with medical marijuana. And if there wasn't a lot packed into this episode, Bob even gets a wedding invite!

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Bill Burr has a lot to say about Bob and his podcast, so the two friends enjoy busting each other's chops throughout the course of this episode. Bill also chats about how much he loves Golden Girls and Bob wonders if bald eagle should be spelled "balled." Plus, the two comedians hope that everyone finally embraces video conferencing after all this is over.

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Bob connects with two essential workers to talk about their experiences helping during the pandemic. One caller, Chris, has been working at an indoor farm and donating food to those in need and Bob chats with him about what it's been like to readjust to co-habiting with a roommate who was usually absent. And later, Bob calls up Wendy to discuss how to stay healthy while delivering food with DoorDash and why small sacrifices are so important to keep everyone safe.

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How do you keep kids preoccupied when they're stuck at home? Bob chats with a caller from St. Louis about how he's keeping his kids busy as everyone's stuck inside, plus the two chat about why Dirty Work had to be PG-13 and what Bob's favorite part of the R-rated version was. Plus, a second caller enlists Bob's help on her psychology project for school as they discuss if technology has helped or worsened our connections.

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Nikki Glaser calls up Bob from her family's home in St. Louis to talk about what it's like to be quarantining with your parents (and bringing a whole new meaning to the term "pot roast"). She and Bob settle the debate of "comic" or "comedian" and Nikki weighs in her thoughts on acting, her experience writing a show for Quibi, and the anxiety around catching up on group texts. Plus, Nikki and Bob wonder if she can actually see into the future and if she possibly prevented herself from getting struck by lightning.

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Bob spends some time on the phone with a couple of fans from opposite ends of the United States! First, a caller wants to chat about the genius of Norm McDonald and Rodney Dangerfield, so Bob tells a story about Rodney Dangerfield waiting to meet up with porn star pal, Ron Jeremy. And later, a high school English teacher chats with Bob about what it's like to care for your students remotely and Bob even gives a little bit of advice to her students.

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Bob's friend, John Mayer picks up the phone to discuss what he's been up to while sheltering in place. Covering everything from what makes a good pun to why recently he's been writing ditties more often than longer songs. Plus, Bob and John reminisce about the first time John did stand up and John advises why it’s good to just sit and stare at a guitar before you even try to learn it.

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Legendary writer and television show creator, Norman Lear (One Day at a Time, All in the Family) calls up Bob to catch up about everything from the difficulties of splitting time between family and TV work to what it was like as a Radio Operator in a B-17 during World War II. Plus, Norman talks the joy of saving the new One Day at a Time from cancellation gives his secret on why he’s always been able to stay in the moment.

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Bob’s calling up some fans and wants to know how they’re doing, but one fan in particular wants to skip straight to the punchline and tell Bob a joke! This episode truly has the biggest range of emotion as Bob catches up with Los Angeles radio host, Ellen K and clarify a misunderstanding from their last meeting, while later Bob is moved to tears by the struggles of one caller who’s taking care of his mother. Plus, Bob chats with a caller all about blue comedy and keeping things light when things are tough.

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