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Brain Natriuretic Peptide (BNP) Lab Values
Overview
BNP
Normal Value Range
Pathophysiology
Special considerations
Lab value elevations
Nursing Points
General
Normal value range
100 pg/mL
Pathophysiology
Increased pressure overload due to increased SVR or volume
Ventricular stretching causes release of BNP into bloodstream
BNP released to aid in stress due to overload by:
Increases excretion of sodium in urine = natriuresis
Sodium follows water
Decreased intravascular volume
Decreased workload on the heart = improved cardiac function
Special considerations
Lavender tube (EDTA)
NT-proBNP may be requested instead
Submit in serum separator tube (tiger top)
Elevated lab values
>100 pg/mL – heart failure likely
The higher the value, the more likely the diagnosis of heart failure
Assessment
Assess patient for acute exacerbation of heart failure
Lung sounds
Oxygen status
Need for supplemental oxygen
Radiographic evaluation
May need diagnostics for evaluation
Echocardiogram can determine contractility function
Therapeutic Management
Treatment
Treat heart failure
Diurese
Improve contractility
Nursing Concepts
Lab Values
Perfusion
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By Jon Haws RN: Critical Care Nurse & NCLEX Educator
4.3
127127 ratings
Overview
BNP
Normal Value Range
Pathophysiology
Special considerations
Lab value elevations
Nursing Points
General
Normal value range
100 pg/mL
Pathophysiology
Increased pressure overload due to increased SVR or volume
Ventricular stretching causes release of BNP into bloodstream
BNP released to aid in stress due to overload by:
Increases excretion of sodium in urine = natriuresis
Sodium follows water
Decreased intravascular volume
Decreased workload on the heart = improved cardiac function
Special considerations
Lavender tube (EDTA)
NT-proBNP may be requested instead
Submit in serum separator tube (tiger top)
Elevated lab values
>100 pg/mL – heart failure likely
The higher the value, the more likely the diagnosis of heart failure
Assessment
Assess patient for acute exacerbation of heart failure
Lung sounds
Oxygen status
Need for supplemental oxygen
Radiographic evaluation
May need diagnostics for evaluation
Echocardiogram can determine contractility function
Therapeutic Management
Treatment
Treat heart failure
Diurese
Improve contractility
Nursing Concepts
Lab Values
Perfusion
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