Breakthroughs

Physicians are notorious for prescribing antibiotics as a "quick fix" when they aren't necessary. There are many reasons why, and Jeffrey Linder, MD, MPH, dives into those and discusses effective ways to reduce the number of inappropriate prescriptions by working with physicians. Originally released in fall 2018, this episode is still timely as the over prescription can lead to dangerous side effects for patients including antibiotic resistance.

Northwestern scientists Yuan Luo, PhD, and Catherine Gao, MD, discuss a study they conducted using the artificial intelligence chatbot, ChatGPT. The results showcase the online tool's ability to produce convincing medical research abstracts. They also discuss the tool's potential to help with writing-intensive tasks in healthcare and medical research.

A theoretical neuroscientist, Ann Kennedy, PhD, is investigating neural computation and the structure of behavior. In this episode, she talks about her recent research in the area of aggression and how it's regulated in the brains of animals. She was recently named the winner of the 2022 Eppendorf and Science Prize for Neurobiology.

Parkinson's disease is the second most prevalent neurodegenerative disease, and nearly one million people have Parkinson's disease in the U.S. A $30 million dollar, phase 3 clinical trial at Northwestern is investigating whether exercise can slow Parkinson's disease progression. Daniel Corcos, PhD, a professor of Physical Therapy and Human Movement Sciences, is leading the trial and explains what he hopes to accomplish.

Interested in the study? Learn more: https://www.feinberg.northwestern.edu/research/clinical-research/trials/index.html?id=STU00211903

To have the greatest impact on human health, biomedical research findings and evidence-based practices need to be implemented into routine healthcare. What is implementation science, and how can we ensure research successfully makes an impact? Rinad Beidas, PhD, and Sara Becker, PhD, discuss the field and its future as a research priority at Northwestern University Feinberg School of Medicine.

There's been an uptick in childhood food allergies in recent years, and new evidence from Northwestern shows they're also becoming more common in adults. Many of the reactions to these allergies are life-threatening. Why is this increase happening, and how can we keep people affected by food allergy safe? Ruchi Gupta, MD, MPH, is trying to answer those questions. This a rewind episode that originally was published in 2019.

A Northwestern Medicine course called Cooking Up Health is giving medical students, trainees and health professionals the opportunity to learn culinary medicine and food-as-medicine science concepts. Melinda Ring, MD, created the course and explains how it can improve the health of patients and train more nutrition-aware physicians.

Understanding how genes function is a vital part of understanding how to better treat cancer. Research led by Mazhar Adli, PhD, is grounded in the development of a systematic approach to identify the function of each gene in the human body. His team aims to discover novel therapeutic drug combinations to prevent cancer development and chemotherapy resistance.

Bariatric surgery is proving to be an effective tool to help teenagers with severe obesity lose weight and reverse the progression of weight-related conditions, according to findings from the Teen Longitudinal Assessment of Bariatric Surgery study (Teen-LABS). Thomas Inge, MD, PhD, principal investigator of Teen-LABS, shares results of the study, which is the only multicenter National Institute of Health sponsored research on adolescent bariatric surgery.

How are habits – both good and bad – formed in the brain, and what role do habits play in diseases of the brain? These are some of the questions neuroscientist, Talia Lerner, PhD, is investigating in her lab. Her recent study, published in Cell Reports, may change the overall understanding of how habits are formed and could be broken.