This week on Calling in Sick, I'm sitting down with Kevin Crosson — advocate, speaker, and one of the most documented cases of vaccine-induced cardiac and immune injury in the country. And this conversation is not what you think it is.

This is an episode about what happens when a rare but real medical event becomes so politically charged that the patients suffering from it can't get diagnosed, treated, or believed.

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This week on Calling in Sick, Dr. Zach Spiritos is back for to chat about one of the most exciting developments in chronic illness treatment that almost nobody is talking about. Microdosing GLP-1s,  not for weight loss, but inflammation and disease management.

Specifically, we're diving into:

Plus the honest conversation about where the research actually is, the systemic bias against women's health in clinical trials, and why cautious optimism is the right posture for this community right now.

🤍

xx, Alex

💬 Comment: Have you ever tried a GLP-1 for anything other than weight loss — and what happened?

TIMESTAMP:

Intro:

00:00:00 Welcome back to Calling in Sick!

00:00:22 Introduction of Guest Dr. Zack Spirtos

Use of GLP-1s Beyond Weight Loss:

00:05:58 What is a GLP-1?

00:07:51 Pre-clinical and Observational Data

00:11:00 Exploring GLP-1s as a Treatment Modality for IBS and MCAS

00:12:28 The "Flipped Clinic" effect of GLP-1s

How to use GLP-1s for Chronic Illness Management:

00:14:09 Responsibly Micro-Dosing Chronic Illness Patients

00:17:13 Assessing Good Candidates and Cautions for Eating Disorders

00:20:07 Titrating Medications and Phased Treatment

The Future of Chronic Illness Research:

00:24:21 Squeaky Wheels and Shifting Paradigms in Medical Funding

00:28:00 Accessibility and the Role of Compounding Pharmacies

00:30:26 Academics vs. Independent Providers in Western Medicine

00:31:55 Turning Down the Volume on POTS, MCAS, and hEDS

Conclusion:

00:35:58 Thank You for Listening to the 100th Week of Calling in Sick!!

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• Substack - https://substack.com/@callinginsickpod?

Connect with our Guest, Dr. Spiritos!

• Instagram - https://www.instagram.com/drzacspiritos/?hl=en

• TikTok - https://www.tiktok.com/@dr.zac.spiritos

• EverBetter Medicine - https://everbettermedicine.health/

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#GLP1 #GLP1ForChronicIllness #MCAS #MastCellActivationSyndrome #ChronicIllness #Ozempic #Semaglutide #BrainFog #GutHealth #ChronicIllnessTreatment #SpoonieLife #InvisibleIllness #DrZachSpiritos #EverBetterMedicine #Dysautonomia #POTS #hEDS #Trifecta #CallingInSickPodcast #AlexWildeson

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This week on Calling in Sick — it’s EPISODE 100!!! And for this milestone, we brought back the MOST REQUESTED guest in the history of this podcast… Dr. Zach Spiritos. He’s a double board-certified neurogastroenterologist at EverBetter Medicine and this week we’re getting into his zone of expertise. Come back on Wednesday for our discussion on GLP-1s as a new treatment option!

But today, we’re diving into:

🤍

xx, Alex

💬 Comment: Do you have one, two, or all three of the trifecta? If so, how long did it take you to get diagnosed?

TIMESTAMP:

Intro:

00:00:00 Welcome back to Calling in Sick!

00:00:31 Introduction of Guest Dr. Zack Spiritos

The 411 on POTS:

00:02:55 Deep Dive into POTS (Postural Orthostatic Tachycardia Syndrome)

00:04:40 Subtypes & Mechanisms of POTS

00:07:43 POTS Diagnostic Testing (Nasaline vs. Tilt Table Test)

00:11:17 Treatment & Lifestyle Changes for POTS Patients

The 411 on EDS & hEDS:

00:19:13 Demystifying hEDS (Hypermobile Ehlers-Danlos Syndrome)

00:26:42 Treatment Strategies

00:34:01 Fragmented Healthcare & Finding a "Unicorn" Provider

The 411 on MCAS:

00:37:54 Unpacking MCAS (Mast Cell Activation Syndrome) & Barrier Theory

00:43:10 The Connection Between MCAS and Endometriosis

00:46:24 The "Vacation Phenomenon" & Environmental Factors

The Trifecta:

00:53:59 Identifying Less Obvious Symptoms (Brain Fog & Severe Bloating)

00:56:36 Medical PTSD & Formulating Compound Medication

Conclusion:

00:58:59 One Brain Cell Segment: Shrinking (Apple TV)

01:04:08 Thank you for listening!

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Connect with our Guest, Dr. Spiritos!

• Instagram - https://www.instagram.com/drzacspiritos/?hl=en

• TikTok - https://www.tiktok.com/@dr.zac.spiritos

• EverBetter Medicine - https://everbettermedicine.health/

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#MCAS #POTS #EDS #hEDS #Trifecta #MastCellActivationSyndrome #PosturalOrthostaticTachycardiaSyndrome #EhlersDanlosSyndrome #ChronicIllness #SpoonieLife #InvisibleIllness #DrZachSpiritos #EverBetterMedicine #EpithelialBarrier #ChronicIllnessTrifecta #Dysautonomia #ConnectiveTissue #AutoimmuneDisease #CallingInSickPodcast #AlexWildeson

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This Wednesday on Calling in Sick, Kati Morton, LMFT is back for the a new segment… “Is this Bad Advice?!” We are taking the most common mental health advice given to people with chronic illness and asking one specific question: is this actually good advice… or is it secretly spiking your need for control?

Tune in to hear Kati and my honest verdict on:

Join us for a conversation about why some very well-meaning advice lands so badly in bodies that are already white-knuckling everything. 🤍

xx, Alex

💬 Comment: Which piece of advice on this list has frustrated you the most — and what do you wish people said instead?

TIMESTAMPS:

00:00:00 Intro to guest Kati Morton

IS THIS BAD ADVICE:

00:00:34  "Just focus on what you can control."

00:02:22  "Anxiety is causing your chronic illness."

00:05:03  "You need to just accept your illness and let go."

00:07:41  "Mindfulness will help you with your chronic pain."

00:12:44  "Having a rigid routine is the best thing for your chronic illness."

00:15:07  "Health anxiety is just hypochondria."

00:16:23  "You need to grieve the life you had before."

00:22:05  "Self-care will help manage your chronic illness."

00:22:32  "Your mindset affects your physical health, so just work on your mindset."

00:22:50  "If therapy isn't working for you, you just have the wrong therapist."

CONCLUSION:

00:28:10 Connect with Kati Morton online and read her books

00:30:41 Thank you for listening, subscribing, and calling in sick with us!

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Connect with our guest, Kati Morton!

• Instagram - https://www.instagram.com/katimorton/

• TikTok - https://www.tiktok.com/@katimorton

• YouTube -  https://www.youtube.com/user/KatiMorton

• Podcast (Ask Kati Anything) - https://www.youtube.com/@askkatianything

• Website - https://katimorton.com/

• Buy her latest book here - https://amzn.to/3RYiSDG

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#ChronicIllnessMentalHealth #KatiMorton #BadAdvice #ChronicIllness #HealthAnxiety #ToxicPositivity #MentalHealth #TherapyTools #Acceptance #ChronicIllnessAdvice #SpoonieLife #InvisibleIllness #Perfectionism #PeoplePleasing #ChronicPain #Mindfulness #SelfCare #WellnessCulture #CallingInSickPodcast #AlexWildeson

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This week on Calling in Sick, I'm sitting down with Kati Morton, LMFT — licensed marriage and family therapist, author of Why Do I Keep Doing This, Traumatized, and Are U Ok?, and one of the most trusted voices in accessible mental health online with 1.5 million YouTube subscribers. 

This Monday, we're diving into:

If you have ever found yourself white-knuckling your routine, your diet, your relationships, or your work schedule while your body does whatever it wants… this episode is going to explain so much. 🤍

xx, Alex

💬 Comment: What is the ONE area of your life where you notice the need for control showing up the most?

TIMESTAMPS:

00:00:47 Intro to the Psychology of Control with guest Kati Morton

The Need for Control & Chronic Illness:

00:01:20 The illusion of control and body responses

00:05:51 Duality and processing freeze energy vs. toxic positivity

Maladaptive Control Coping Scenarios:

00:11:37 Breakdown of people pleasing behaviors

00:14:26 Perfectionism and “earning worth”

00:20:00 Eating disorders, exercise addiction, and lifestyle rigidity

00:25:51 All-or-nothing thinking cycles

Relational Control & Caregiver Dynamics:

00:26:50 The social impacts of chronic illness (e.g. canceling plans and how it impacts you AND others)

00:29:48 Why caregivers get burnt out

00:36:06 Catching anxiety before the fight, flight, or freeze state

Healing and Coping Tools:

00:38:29 The "Inner Detective" reframe and addressing past trauma

00:49:12 Reprogramming the brain's negativity bias

00:54:27 CBT tool: "Play it Out" (Worst, best, and most likely case)

00:57:32 Somatic releases and moving out of freeze mode

Conclusion:

01:00:00 One Brain Cell Show: Ted Lasso, Gilmore Girls, and some good reads

01:04:32 Connect with Kati Morton online

01:05:47 Thank you for listening!

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Connect with our guest, Kati Morton!

• Instagram - https://www.instagram.com/katimorton/

• TikTok - https://www.tiktok.com/@katimorton

• YouTube -  https://www.youtube.com/user/KatiMorton

• Podcast (Ask Kati Anything) - https://www.youtube.com/@askkatianything

• Website - https://katimorton.com/

• Buy her latest book here - https://amzn.to/3RYiSDG

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#ChronicIllnessAndControl #MentalHealth #ChronicIllness #KatiMorton #PeoplePleasing #Perfectionism #CBT #TherapyTools #ChronicIllnessMentalHealth #InvisibleIllness #SpoonieLife #EatingDisorders #ExerciseAddiction #PassiveAggression #CopingMechanisms #ChronicPain #Anxiety #TherapyTikTok #CallingInSickPodcast #AlexWildeson

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This week on Calling in Sick, Max Swiergol is back for a deep dive on one of the most viral and most misunderstood topics in the chronic illness and wellness space right now… PEPTIDES!!!

You've seen them all over TikTok. You've probably heard of BPC-157. And you have almost certainly seen someone claim a peptide changed their life. But the clinical research is almost nonexistent… and that gap between popularity and evidence is exactly where this community is most vulnerable.

We're diving into:

The bottom line from this conversation: peptides are genuinely promising. The research is genuinely lacking. And this community deserves to know the difference.

xx, 

Alex

💬 Comment: Have you ever tried a peptide, and what was your experience?

TIMESTAMPS:

Intro:

00:00:00 Welcome back to Calling in Sick!

The Viral Rise of Peptides

00:00:16 What are peptides and why are they viral?

00:04:44 Navigating the peptide market as a chronic illness patient

FDA Regulatory Discussions and Prominent Peptides:

00:08:21 Why the government is talking about recategorizing peptides

00:09:20 The Pharmacy Compounding Advisory Committee vote outcomes

00:11:14 A deep dive on BPC-157 in the chronic illness space

00:14:08 Dr. Abud Bakri and peptide transparency (ne1.study)

00:17:07 Endo 205 and endometriosis research

00:20:08 AI drug discovery and peptide predictors

00:24:00 New research around testing for Endometriosis

Conclusion:

00:28:03 Where to find Max Dose online

00:29:18 Thank you for listening!

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Connect with our guest, Max Swiergol!

• Instagram - https://www.instagram.com/themaxdose/

• TikTok - https://www.tiktok.com/@themaxdose

• YouTube - https://www.youtube.com/@Themaxdoseyt

• Sign up for his newsletter - https://tr.ee/TdjGmsOp4V

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Relevant Episode Links:

• Dr. Abud Bakri - https://www.instagram.com/p/DZDYBIShrjW/

• Peptide Research Transparency - https://ne1.study/

• ENDO-205 - https://seed.nih.gov/portfolio/nih-portfolio-company-showcase/endocyclic-therapeutics

#Peptides #BPC157 #Endo205 #FDAPeptides #ChronicIllness #PeptideTherapy #Endometriosis #ChronicIllnessTreatment #SpoonieLife #InvisibleIllness #GLP1 #PersonalizedMedicine #PatientAdvocacy #ClinicalTrials #WellnessResearch #ChronicPain #AutoimmuneDisease #PeptideResearch #CallingInSickPodcast #AlexWildeson

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This week on Calling in Sick, I'm sitting down with Max Swiergol, osteopathic medical student, research enthusiast, and one of the most accessible voices translating cutting-edge science for the chronic illness community online. This episode is one of the most practically useful we have ever done.

We're diving into:

If you have ever read a study online and not known what to do with it, or seen a supplement brand quote research and felt something was off, this episode is going to give you all the tools you need.

AND! Come back on Wednesday to hear our chat about… PEPTIDES!

xx, Alex

💬 Comment: Have you ever brought a research paper to a doctor's appointment? What happened?

TIMESTAMPS:

Intro:

00:00:00 Welcome back to Calling in Sick!

00:00:11 Meet Max Swiergol

How to Read & Understand Medical Research as a Patient:

00:05:44 How to find good research

00:07:30 What medical journals carry credibility (and which don’t!)

00:09:34 Identifying selection bias online

00:13:28 The hierarchy of medical evidence (The Evidence Pyramid)

00:18:30 Conflicts of interest and the peer-review process

Personalized Medicine & Treatments & the Clinical Trial Process:

00:25:36 The transition to personalized care for treatment

00:31:02 How CAR-T cell therapy is revolutionizing autoimmune treatment

00:39:40 FDA Approval Process(Pre-clinical testing, Phase 1-3)

00:45:57 Why it takes so long to approve medications

Conclusion:

00:54:33 One Brain Cell Show (YouTube travel vlogs)

00:56:52 Where to find Max Dose online

00:58:28 Thank you for listening!

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Connect with our guest, Max Swiergol!

• Instagram - https://www.instagram.com/themaxdose/

• TikTok - https://www.tiktok.com/@themaxdose

• YouTube - https://www.youtube.com/@Themaxdoseyt

• Sign up for his newsletter - https://tr.ee/TdjGmsOp4V

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One Brain Cell YT Shows:

The everlasting fish ponds: https://www.atlasobscura.com/places/longyou-caves

Relevant Episode Links:

• New PPD Treatments - https://reunionneuro.com/2026/01/20/reunion-neuroscience-presents-full-data-from-reconnect-phase-2-clinical-trial-of-re104-for-the-treatment-of-postpartum-depression-ppd-at-acnp-annual-meeting/

• ENDO-205 - https://seed.nih.gov/portfolio/nih-portfolio-company-showcase/endocyclic-therapeutics

#MedicalResearch #ChronicIllness #CARTTherapy #GeneEditing #FDAApproval #ChronicIllnessTreatment #PatientAdvocacy #ResearchLiteracy #AutoimmuneDisease #SpoonieLife #InvisibleIllness #ClinicalTrials #PersonalizedMedicine #ChronicIllnessAwareness #MedicalBias #SupplementIndustry #ChronicPain #HealthResearch #CallingInSickPodcast #AlexWildeson

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This week on Calling in Sick, Nitika Chopra is back to discuss the ONE thing that a lot of people in the chronic illness community have been quietly waiting for someone to say out loud.

We're getting into the tools and identity shifts that don't always get talked about in this space, the ones that feel a little vulnerable to share, and the ones that have actually moved the needle.

Tune in to hear more about:

xx, 

Alex

💬 Comment: Have you ever explored energy healing or nervous system work… and did it help? Share your approach!!!!

TIMESTAMPS:

Intro:

00:00:00 Welcome back to Calling in Sick!

00:00:06 Intro to Nitkia Chopra

The Astrologer and the Nervous System Coach:

00:00:24 Nitika’s diagnosis and the decision to seek an alternative approach

00:03:50 The confrontational astrologer session and "ego death"

00:04:15 Chart readings and unpacking survival mechanisms and pathologies

00:07:06 Transitioning from fight-or-flight through nervous system work

00:10:18 Discussing the MANY routes you can take to support your nervous system

Perspectives on Fight-or-Flight and Victimhood:

00:11:42 Addressing undercurrents of victimhood and trauma states

00:13:56 Understanding chronic illness as an intelligent adaptation by the nervous system

00:16:01 Understanding how others can interpret our seasons of deep fight-or-flight

00:17:34 Nitika’s current state of illness and managing active symptoms

00:19:13 Analyzing chronic illness as a blended space of biology and emotion

Chronic Illness Hot Takes:

00:27:14 Can positive thinking heal chronic illness?

00:29:55 Should you 100% leave western medicine behind for alternative medicine?

00:32:24 Should you be grateful for what your illness has taught you?

00:34:51 Do wellness brands actually care about chronically ill people?

Conclusion:

00:37:03 One Brain Cell picks of the week (Survival of the Thickest on Netflix, Famesick by Lena Dunham)

00:39:00 Where to find Nitica Chopra (@niticachopra)

00:40:36 Thank you for listening (Like, Follow, and Subscribe!)

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Connect with our guest: Nitika Chopra!

• Instagram - https://www.instagram.com/nitikachopra/?hl=en

• Website - https://nitikachopra.com/

• Join ChroniCon - https://chronicon.co/

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#Prednisone #SteroidSideEffects #PrednisoneWeightGain #SteroidRage #PrednisoneSurvivalGuide #ChronicIllness #SpoonieLife #InvisibleIllness #AutoimmuneDisease #MedicalGaslighting #ChronicPain #HealthJourney #Inflammation #SteroidWithdrawal #PrednisoneTaper #MentalHealth #SteroidAnxiety #SpoonieSupport #CallingInSickPodcast #AlexWildeson

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This week on Calling in Sick, I'm sitting down with Nitika Chopra, founder of Chronicon, chronic illness advocate, and someone who has been navigating life with a body that doesn't cooperate since she was 10 years old. We discuss everything from our lifelong fights with chronic illness to finding identity outside of the fight.

Tune into hear more about:

This one hit close to home for me personally. We are in the peaks AND the pits of this life. And this conversation is for both.

xx, Alex

💬 Comment: Has your chronic illness ever become part of your identity in a way that felt hard to let go of?

TIMESTAMPS:

Intro:

00:00:00 Welcome back to Calling in Sick!

00:00:10 Intro to Nitika Chopra

Nitika’s Diagnostic History:

00:02:04 Nitika’s first chronic illness diagnosis at age 10

00:05:42 Growing up in Ohio & feelings of separateness

00:06:17 Developing psoriatic arthritis 10 years later

Young Adulthood & Career Evolution:

00:11:36 Dealing with severe chronic flare-ups in Nitika’s early 20s

00:12:01 The impact of toxic positivity and damaging self-help culture

00:14:03 Physical isolation, medication shifts, and accepting help

00:23:58 What is Myasthenia Gravis & Nitika’s diagnosis story

00:29:44 Weight swings and rapid 40-pound gain from prednisone

The Duality of the Chronic Illness Identity:

00:36:24 Nuances of the chronic illness identity and outgrowing aspects of it

00:41:27 The juxtaposition of needing a freedom to heal while also needing the community that get’s the pits of chronic illness

00:45:00 How Alex’s pregnancy remission state has shifted her identity and relation to chronic illness for the time being

Conclusion:

00:49:25 One Brain Cell picks of the week (Survival of the Thickest (Netflix), Famesick by Lena Dunham)

00:51:22 Where to find Nitika Chopra (@nitakachopra)

00:52:57 Thank you for listening (Like, Subscribe, and Share!)

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• Substack - https://substack.com/@callinginsickpod?

Connect with our guest: Nitika Chopra!

• Instagram - https://www.instagram.com/nitikachopra/?hl=en

• Website - https://nitikachopra.com/

• Join ChroniCon - https://chronicon.co/

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#ChronicIllnessIdentity #NitikChopra #Chronicon #Psoriasis #PsoriaticArthritis #MyastheniaGravis #ChronicIllness #SpoonieLife #InvisibleIllness #AutoimmuneDisease #ChronicIllnessCommunity #ToxicPositivity #RemissionGuilt #ChronicIllnessAwareness #IdentityShift #BelongingWithoutBeingSick #ChronicPain #MentalHealth #CallingInSickPodcast #AlexWildeson

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This week on Calling in Sick, I’m answering all your pregnancy Q&A!

We're diving into:

🩺 How to actually start your pregnancy journey with chronic illness — the preconception appointment you NEED to make now!!!

👶 Second trimester update — autoimmune status, ultrasound anxiety during gap, and how I’m feeling overall

🧬 Why we’re NOT scared about passing on my chronic illness to our kids

💉 My birth plan — My thoughts on my delivery, epidural & pain medication, and if I feel guilt about my decisions

🍼 Feeding plans — How I’m thinking about breastfeeding, freeze-dried donor milk, and formula

🛏️ Sleep planning — How we’re trying to stay ahead of the sleep deprivation (lol!!)

🛒 My top Registry picks — and the things that have already changed !!!

xx, 

Alex

💬 Comment: What's the one pregnancy question you wish someone had answered honestly for you?

TIMESTAMPS:

Intro:

00:00:00 Welcome back to Calling in Sick!

00:00:54 Coping with pregnancy anxiety, food rules, and parasite fears

00:01:56 Substack updates: group chats and weekly posts

Q&A - Pregnancy & Chronic Illness Planning:

00:02:56 Navigating pregnancy planning with chronic illness

00:05:42 Mid-pregnancy check-in

00:11:28 My thoughts on genetic testing and passing on chronic illnesses

Q&A - Nursery, Birth Plans & Registries:

00:14:01 What we’ve done to prep his nursery so far

00:16:00 My thoughts on preparing for labor

00:17:44 Ditching the medication guilt during pregnancy

00:19:04 How we are (trying!!) to prepare for postpartum life + sleep deprivation

00:22:13 The HARDEST picks on my registry - Strollers, mattresses, and pumps

Conclusion:

00:26:14 Are we going to change our minds… again!?

00:27:28 Thank You for Listening!!!

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