In this episode, we will discuss about the role of free circulating tumor DNA testing in early cancer detection, the current limitations of existing cancer screening modalities and the need for more proactive approaches to cancer care. Dr. Venstrom explains how Grail's technology works, using a blood test to detect abnormal patterns of DNA shedding from tumors. He emphasizes the importance of the cancer signal of origin and how it can guide targeted diagnostic and therapeutic interventions.