ZOE Science & Nutrition

Can bigger muscles really help burn fat and keep you young? | Dr. Vonda Wright


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Do you track your weight, hoping to see the numbers drop? What if the scale is deceiving you about true health, muscle, and healthy aging? Many believe they understand the keys to a vibrant later life, but conventional wisdom often overlooks a critical truth. 

This oversight could be inadvertently putting your future well-being on a slippery slope of decline, even if you feel like you're doing everything right. You might be losing something far more valuable than just fat.

In this episode, Dr. Vonda Wright, a double board-certified orthopaedic surgeon with over 20 years of clinical and research experience, joins to reveal the truth about muscle and body composition in later years. 

A best-selling author, Vonda reveals why muscle is not merely for aesthetics but a metabolic powerhouse crucial for energy, glucose control, and preventing age-related frailty. Learn how to truly 'lean up' and why it’s vastly more important than just losing pounds. 

*Naturally high in copper which contributes to normal energy yielding metabolism and the normal function of the immune system

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Timecodes

00:00 Do your scales lie about muscle?

00:34 Do muscles stop sugar spikes?

03:45 Why muscles are hormonal powerhouses

06:10 Can you reverse cell aging?

07:20 The dangers of high blood sugar

11:05 Are you sitting down for too long?

15:05 Shocking difference in muscle scans

18:40 Is it ever too late to build muscle?

20:20 Can exercise rejuvenate your cells?

24:50 The risk of losing muscle

28:37 Should you stop weighing yourself?

31:47 Surprising truth about muscle vs. fat

33:50 Does perimenopause affect metabolism?

39:05 Where is fat really stored?

42:10 Can you lift for life by focusing on strength?

51:00 Should you check your heart before high intensity exercise?


📚Books by our ZOE Scientists

The Food For Life Cookbook

Every Body Should Know This by Dr Federica Amati

Food For Life by Prof. Tim Spector


Free resources from ZOE

Live Healthier: Top 10 Tips From ZOE Science & Nutrition

Gut Guide - For a Healthier Microbiome in Weeks 


Mentioned in today's episode

Moderate-intensity treadmill running promotes expansion of the satellite cell pool in young and old mice FEBS Press (2013)

Physical training reduces cell senescence and associated insulin resistance in skeletal muscle Molecular Metabolism (2025)

Current knowledge and scientific trends in myokines and exercise research in the context of obesity Frontiers in Medicine (2024)

The New Science of Musculoskeletal Aging in Bone, Muscle, and Tendon/Ligament Masterful Care of the Aging Athlete (2018)

Low back pain: a call for action The Lancet (2018)


Have feedback or a topic you'd like us to cover? Let us know here.

Episode transcripts are available here.

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