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Eighty-one percent of physicians are already using AI in practice, more than double the rate from just three years ago. The tools are moving faster than the rules, and nobody has agreed on who gets to write them.

Dr. John Whyte, CEO of the American Medical Association, joins hosts David E. Williams and John Driscoll to discuss why the medical community needs to lead the conversation on AI guardrails rather than wait for Washington to catch up, and why the most urgent regulatory question right now involves AI chatbots in mental health, where one in six American adults are already using them with no meaningful oversight in place.

🎙️⚕️ABOUT DR. JOHN WHYTE
John J. Whyte, MD, MPH is the CEO and Executive Vice President of the American Medical Association, the nation's largest physician organization. Prior to the AMA, he served as Chief Medical Officer at WebMD, Director of Professional Affairs and Stakeholder Engagement at the FDA's Center for Drug Evaluation and Research, Chief Medical Expert and VP of Health and Medical Education at Discovery Channel, and held a role at CMS where he helped formalize Medicare's national coverage decision process. He is a board-certified internist with an MD from Hahnemann University School of Medicine, residency training at Duke University Medical Center, and an MPH in Health Policy and Management from Harvard University. He has also served as a health services research fellow at Stanford University and is the author of five best-selling books.

🎙️⚕️ABOUT CARETALK
CareTalk is a weekly podcast that provides an incisive, no B.S. view of the US healthcare industry. Join co-hosts John Driscoll (President U.S. Healthcare and EVP, Walgreens Boots Alliance) and David Williams (President, Health Business Group) as they debate the latest in US healthcare news, business and policy. 

✨THIS VIDEO BROUGHT YOU BY:

PIM Health:
At PIM Health, we’re building real-time payment infrastructure where providers don’t wait weeks to get paid, patients don’t leave without knowing exactly what they owe, and employers stop flying blind on their own plan spend. AR burden, gone. Surprise bills, gone. Prior auth delays, gone. Denials and appeals, gone.

Learn what PIM Health is building here

Vector Sciences:
Dr. Dan Barouch and active angel investor and biotech lawyer Kris Brown are excited to join an upcoming CareTalk podcast discussion about the future of vaccines, biodefense preparedness, and why next-generation adenoviral and mucosal vaccine technologies may play an important role alongside mRNA approaches in addressing future global outbreaks. Looking forward to discussing how scalable, durable, and potentially transmission-blocking vaccine platforms could reshape pandemic response and global public health.

Hear more about Vector Sciences here

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⚙️CareTalk:  Healthcare. Unfiltered. is produced by Grippi Media Digital Marketing Consulting.

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There are very few cures for cancers that have already spread. So what does a good outcome actually look like?

In this clip from our episode “How Targeted Radiotherapy Is Changing Cancer Care”, host David E. Williams and John Babich, Founder, President, and Chief Scientific Officer of Ratio Therapeutics, break down what extending life with quality really means in cancer care, and why giving someone eight more months where they can still live their life is the philosophy driving the work at Ratio Therapeutics.

Listen to the full episode here

🎙️⚕️ABOUT JOHN BABICH
John W. Babich, a native of New York City, holds a BS in pharmaceutical sciences from St. John’s University and a PhD in radiopharmaceutical chemistry from The Institute of Cancer Research in London. He began his career at Brookhaven National Laboratory and later NASA, focusing on cardiovascular imaging. Babich co-founded Molecular Insight Pharmaceuticals in 1998, where he developed several radiopharmaceuticals, including a PSMA inhibitor for prostate cancer now in Phase 3 trials. In 2017, he founded Noria Therapeutics, which was sold to Bayer in 2021, leading to the creation of Ratio Therapeutics.

🎙️⚕️ABOUT HEALTH BIZ PODCAST
HealthBiz is a CareTalk podcast that delivers in-depth interviews on healthcare business, technology, and policy with entrepreneurs and CEOs. Host David E. Williams — president of the healthcare strategy consulting boutique Health Business Group — is also a board member, investor in private healthcare companies, and author of the Health Business Blog. Known for his strategic insights and sharp humor, David offers a refreshing break from the usual healthcare industry BS.

Need a Strategy Partner?
For over 20 years, Health Business Group has helped healthcare software companies, tech-enabled services businesses, life sciences companies, and payers make smarter strategic decisions. Led by podcast host David Williams, the firm advises clients on sharpening AI positioning, entering new segments, and building commercial strategies for value-based care. See examples of our work at healthbusinessgroup.com/

GET IN TOUCH
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⚙️CareTalk:  Healthcare. Unfiltered. is produced by Grippi Media Digital Marketing Consulting.

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For decades, cancer treatment has rested on three pillars: surgery, chemotherapy, and external beam radiation. A fourth is now taking shape, and it is drawing billions in investment from some of the largest pharmaceutical companies in the world.

John Babich, Founder, President, and Chief Scientific Officer of Ratio Therapeutics, joins host David E. Williams to explain how targeted radiotherapeutics pair a tumor-seeking molecule with a radioactive payload, delivering radiation to cancer cells while sparing healthy tissue. He also unpacks what Pluvicto’s success in prostate cancer signals for the future of radioligand therapy.

🎙️⚕️ABOUT JOHN BABICH
John W. Babich, a native of New York City, holds a BS in pharmaceutical sciences from St. John’s University and a PhD in radiopharmaceutical chemistry from The Institute of Cancer Research in London. He began his career at Brookhaven National Laboratory and later NASA, focusing on cardiovascular imaging. Babich co-founded Molecular Insight Pharmaceuticals in 1998, where he developed several radiopharmaceuticals, including a PSMA inhibitor for prostate cancer now in Phase 3 trials. In 2017, he founded Noria Therapeutics, which was sold to Bayer in 2021, leading to the creation of Ratio Therapeutics.

🎙️⚕️ABOUT HEALTH BIZ PODCAST
HealthBiz is a CareTalk podcast that delivers in-depth interviews on healthcare business, technology, and policy with entrepreneurs and CEOs. Host David E. Williams — president of the healthcare strategy consulting boutique Health Business Group — is also a board member, investor in private healthcare companies, and author of the Health Business Blog. Known for his strategic insights and sharp humor, David offers a refreshing break from the usual healthcare industry BS.

Need a Strategy Partner?
For over 20 years, Health Business Group has helped healthcare software companies, tech-enabled services businesses, life sciences companies, and payers make smarter strategic decisions. Led by podcast host David Williams, the firm advises clients on sharpening AI positioning, entering new segments, and building commercial strategies for value-based care. See examples of our work at healthbusinessgroup.com/

✨THIS VIDEO BROUGHT YOU BY:

PIM Health:
At PIM Health, we’re building real-time payment infrastructure where providers don’t wait weeks to get paid, patients don’t leave without knowing exactly what they owe, and employers stop flying blind on their own plan spend. AR burden, gone. Surprise bills, gone. Prior auth delays, gone. Denials and appeals, gone.

Learn what PIM Health is building here

Vector Sciences:
Dr. Dan Barouch and active angel investor and biotech lawyer Kris Brown are excited to join an upcoming CareTalk podcast discussion about the future of vaccines, biodefense preparedness, and why next-generation adenoviral and mucosal vaccine technologies may play an important role alongside mRNA approaches in addressing future global outbreaks. Looking forward to discussing how scalable, durable, and potentially transmission-blocking vaccine platforms could reshape pandemic response and global public health.

Hear more about Vector Sciences here

GET IN TOUCH
Follow CareTalk on LinkedIn
Become a CareTalk sponsor
Guest appearance requests
Visit us on the web

Support the show

⚙️CareTalk:  Healthcare. Unfiltered. is produced by Grippi Media Digital Marketing Consulting.

Send us Fan Mail

The COVID-19 pandemic proved vaccine platforms can move at unprecedented speed. It also revealed how dangerously narrow the world's response really was, built almost entirely on a single technology.

Dr. Dan Barouch and Kris Brown, Co-Founders of Vector Sciences, join host David E. Williams to discuss why durable pandemic preparedness depends on having multiple vaccine platforms rather than just one, how their Rheovax platform uses mucosal immunity delivered through the nose to block transmission rather than just prevent severe disease, and why public trust in vaccines depends on being honest about what each technology can and cannot actually do.

🎙️⚕️ABOUT DR. DAN BAROUCH
Dan Barouch received his Ph.D. in immunology from Oxford University and his M.D. from Harvard Medical School. He is currently the William Bosworth Castle Professor of Medicine at Harvard Medical School, Director of the Center for Virology and Vaccine Research at Beth Israel Deaconess Medical Center, and a member of the Ragon Institute of MGH, MIT, and Harvard. His laboratory focuses on studying the immunology and pathogenesis of viral infections and developing novel vaccine and treatment strategies. His group has led the development of vaccine candidates for HIV-1, Zika, SARS-CoV-2, tuberculosis, and influenza. His work contributed to the development of the Johnson & Johnson COVID-19 vaccine and the evaluation of multiple COVID-19 vaccines and therapeutics. He was elected to the American Society for Clinical Investigation (2009), Association of American Physicians (2013), and National Academy of Medicine (2020), and he received the King Faisal Prize in Medicine (2023).

🎙️⚕️ABOUT KRISTOPHER BROWN
Kristopher Brown is an active angel investor and entrepreneur who has founded several companies, including Vector Sciences, Inc., and has been the first or second angel investor in over 90 companies over the past 25 years, including Skype, Blockchain, and Compass, as well as a limited partner in a dozen earlier stage venture capital funds spanning life sciences, fintech, media, and digital healthcare. He is also a senior law partner in the Life Sciences & Technology Practice Group at Goodwin Procter LLP, where he has practiced for nearly 35 years and advised on more than 250 transactions in the life sciences sector, including mergers and acquisitions, divestitures, public offerings, licensing transactions, and the formation of investment partnerships and strategic alliances. He holds a degree in Mathematics and Economics from Brown University and a JD from Boston University School of Law, where he served as Executive Editor of the BU Law Review.

🎙️⚕️ABOUT VECTOR SCIENCES
Vector Sciences is a next-generation vaccine platform company focused on developing durable, scalable, and potentially transmission-blocking vaccines using its proprietary RheoVax rhesus adenovirus platform. Founded by leading virologists including Dr. Dan Barouch of Harvard’s Beth Israel Deaconess Medical Center, the company is advancing novel mucosal and intranasal vaccine approaches designed to generate strong local and systemic immunity while potentially improving ease of deployment, reducing cold-chain dependence, and lowering manufacturing complexity. Vector Sciences’ platform is being explored across multiple infectious disease applications, with the broader goal of creating safer, more effective, and more globally deployable vaccines for future pandemic and biodefense preparedness.

Learn more about Vector Sciences here.

🎙️⚕️ABOUT CARETALK
CareTalk is a weekly podcast that provides an incisive, no B.S. view of the US healthcare industry. Join co-hosts John Driscoll (President U.S. Healthcare and EVP, Walgreens Boots Alliance) and David Williams (President, Health Business Group) as they debate the latest in US healthcare news, business and policy. 

GET IN TOUCH
Follow CareTalk on LinkedIn
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Visit us on the web

Support the show

⚙️CareTalk:  Healthcare. Unfiltered. is produced by Grippi Media Digital Marketing Consulting.

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People trust their doctor. They do not trust the bill they get afterward.

In this clip from our episode “Why Healthcare Prices Are Like Fight Club”, host John Driscoll and Mark Cuban, Co-Founder of Cost Plus Drugs, break down why pricing transparency, not just lower prices, was the real reason Cost Plus Drugs earned the trust of patients across the country.

Listen to the full episode here

🎙️⚕️ABOUT MARK CUBAN
Mark Cuban is a self-made billionaire entrepreneur known for his early tech ventures like Broadcast.com, his ownership of the Dallas Mavericks, and his role as a "Shark" on ABC's Shark Tank, investing in numerous startups and expanding into media, film, and healthcare, always championing innovation and disruption. 

In 2019, Mark co-founded Costplusdrugs.com with the aim of lowering generic drug prices for end consumers in the U.S., starting the company after receiving an email from a radiologist named Alex Oshmyansky, who pitched the idea of an online-based pharmacy. He often refers to Cost Plus Drugs as a critique and disruptor of the US health care system, including offering transparent, direct-to-consumer pricing and reducing the role of pharmacy benefit managers. 

Mark has earned a number of accolades including being named to the Texas Business Hall of Fame, the Horatio Alger Award, the SXSW Hall of Fame, Ernst and Young Entrepreneur of the Year, and GQ Man of the Year.

🎙️⚕️ABOUT CARETALK
CareTalk is a weekly podcast that provides an incisive, no B.S. view of the US healthcare industry. Join co-hosts John Driscoll (President U.S. Healthcare and EVP, Walgreens Boots Alliance) and David Williams (President, Health Business Group) as they debate the latest in US healthcare news, business and policy.

GET IN TOUCH
Follow CareTalk on LinkedIn
Become a CareTalk sponsor
Guest appearance requests
Visit us on the web

Support the show

⚙️CareTalk:  Healthcare. Unfiltered. is produced by Grippi Media Digital Marketing Consulting.

Send us Fan Mail

Nobody at the pharmacy counter knows the real price of their medication, and almost nobody in the system actually wants them to.

Mark Cuban, Co-Founder of Cost Plus Drugs, joins host John Driscoll on CareTalk to discuss why pharmacy benefit managers control 85% of drug formularies in this country, how spread pricing quietly inflates the cost of everything from generics to hip replacements, and why true price transparency, not just lower prices, is the real disruption Cost Plus Drugs has brought to a $5 trillion industry.

🎙️⚕️ABOUT MARK CUBAN
Mark Cuban is a self-made billionaire entrepreneur known for his early tech ventures like Broadcast.com, his ownership of the Dallas Mavericks, and his role as a "Shark" on ABC's Shark Tank, investing in numerous startups and expanding into media, film, and healthcare, always championing innovation and disruption. 

In 2019, Mark co-founded Costplusdrugs.com with the aim of lowering generic drug prices for end consumers in the U.S., starting the company after receiving an email from a radiologist named Alex Oshmyansky, who pitched the idea of an online-based pharmacy. He often refers to Cost Plus Drugs as a critique and disruptor of the US health care system, including offering transparent, direct-to-consumer pricing and reducing the role of pharmacy benefit managers. 

Mark has earned a number of accolades including being named to the Texas Business Hall of Fame, the Horatio Alger Award, the SXSW Hall of Fame, Ernst and Young Entrepreneur of the Year, and GQ Man of the Year.

🎙️⚕️ABOUT CARETALK
CareTalk is a weekly podcast that provides an incisive, no B.S. view of the US healthcare industry. Join co-hosts John Driscoll (President U.S. Healthcare and EVP, Walgreens Boots Alliance) and David Williams (President, Health Business Group) as they debate the latest in US healthcare news, business and policy.

🩺 THIS EPISODE IS BROUGHT TO YOU BY:

PIM Health:
At PIM Health, we’re building real-time payment infrastructure where providers don’t wait weeks to get paid, patients don’t leave without knowing exactly what they owe, and employers stop flying blind on their own plan spend. AR burden, gone. Surprise bills, gone. Prior auth delays, gone. Denials and appeals, gone.

Learn what PIM Health is building here

GET IN TOUCH
Follow CareTalk on LinkedIn
Become a CareTalk sponsor
Guest appearance requests
Visit us on the web

Support the show

Support the show

⚙️CareTalk:  Healthcare. Unfiltered. is produced by Grippi Media Digital Marketing Consulting.

Send us Fan Mail

GLP-1 drugs were designed for weight loss. Now they may be showing up in cancer research in a way nobody expected.

In this clip from our episode “The Business & Science Behind the GLP-1 Boom”, hosts David E. Williams and John Driscoll break down what the 2026 ASCO annual meeting revealed about GLP-1s and their potential to reduce cancer progression in lung, breast, colorectal, and liver cancer.

Listen to the full episode here

🎙️⚕️ABOUT CARETALK
CareTalk is a weekly podcast that provides an incisive, no B.S. view of the US healthcare industry. Join co-hosts John Driscoll (President U.S. Healthcare and EVP, Walgreens Boots Alliance) and David Williams (President, Health Business Group) as they debate the latest in US healthcare news, business and policy.

GET IN TOUCH
Follow CareTalk on LinkedIn
Become a CareTalk sponsor
Guest appearance requests
Visit us on the web

Support the show

⚙️CareTalk:  Healthcare. Unfiltered. is produced by Grippi Media Digital Marketing Consulting.

Send us Fan Mail

GLP-1 drugs have produced some of the most consistent weight loss results medicine has ever seen. The business of actually getting them to patients is a different story entirely.

David E. Williams, President of Health Business Group, and John Driscoll, Chairman of UConn Health, break down the CVS Caremark formulary reversal on CareTalk, examining what it reveals about the economics of GLP-1 coverage, and why emerging clinical research on cancer, long COVID, and addiction may push these drugs far beyond their original indication.

🎙️⚕️ABOUT CARETALK
CareTalk is a weekly podcast that provides an incisive, no B.S. view of the US healthcare industry. Join co-hosts John Driscoll (President U.S. Healthcare and EVP, Walgreens Boots Alliance) and David Williams (President, Health Business Group) as they debate the latest in US healthcare news, business and policy.

🩺 THIS EPISODE IS BROUGHT TO YOU BY:

PIM Health:
At PIM Health, we’re building real-time payment infrastructure where providers don’t wait weeks to get paid, patients don’t leave without knowing exactly what they owe, and employers stop flying blind on their own plan spend. AR burden, gone. Surprise bills, gone. Prior auth delays, gone. Denials and appeals, gone.

Learn what PIM Health is building here

GET IN TOUCH
Follow CareTalk on LinkedIn
Become a CareTalk sponsor
Guest appearance requests
Visit us on the web

Support the show

⚙️CareTalk:  Healthcare. Unfiltered. is produced by Grippi Media Digital Marketing Consulting.

Send us Fan Mail

Six million healthcare workers are missing today. By 2030, that number reaches 10 million. No amount of training will ever close that gap.

In this clip from our episode “Is AI the New Dr. Google?”, host David E. Williams and Bertalan Mesko, Director of the Medical Futurist Institute, break down why the healthcare worker shortage is a mathematical problem that only advanced technology can solve.

Listen to the full episode here

🎙️⚕️ABOUT DR. BERTALAN MESKO
Dr. Bertalan Meskó, MD, PhD, widely known as "The Medical Futurist," is a leading global expert on healthcare technology. He serves as the Director of The Medical Futurist Institute and is a Private Professor at Semmelweis University in Budapest, Hungary. With a background as a physician and a PhD in genomics, Dr. Meskó focuses on how tools like artificial intelligence, wearable devices, and robots can improve modern medicine. He has delivered hundreds of keynote presentations at top institutions like Harvard and Stanford. He is also a bestselling author who has been featured by major media outlets such as CNN, TIME, and National Geographic.

🎙️⚕️ABOUT HEALTH BIZ PODCAST
HealthBiz is a CareTalk podcast that delivers in-depth interviews on healthcare business, technology, and policy with entrepreneurs and CEOs. Host David E. Williams — president of the healthcare strategy consulting boutique Health Business Group — is also a board member, investor in private healthcare companies, and author of the Health Business Blog. Known for his strategic insights and sharp humor, David offers a refreshing break from the usual healthcare industry BS.

Need a Strategy Partner?
For over 20 years, Health Business Group has helped healthcare software companies, tech-enabled services businesses, life sciences companies, and payers make smarter strategic decisions. Led by podcast host David Williams, the firm advises clients on sharpening AI positioning, entering new segments, and building commercial strategies for value-based care. See examples of our work at healthbusinessgroup.com/

GET IN TOUCH
Follow CareTalk on LinkedIn
Become a CareTalk sponsor
Guest appearance requests
Visit us on the web

Support the show

⚙️CareTalk:  Healthcare. Unfiltered. is produced by Grippi Media Digital Marketing Consulting.

Send us Fan Mail

The World Health Organization projects a global shortage of 10 million healthcare workers by 2030. No training pipeline can close that gap. The only path forward runs through technology.

Dr. Bertalan Meskó, Founder & Director of the Medical Futurist Institute, joins host David E. Williams to discuss why digital health is first and foremost a cultural transformation rather than a technological one, and why the most important thing any health system leader can do right now is learn how to use AI as the connective interface between an increasingly complex ecosystem of tools, patients, and clinical teams.

🎙️⚕️ABOUT DR. BERTALAN MESKO
Dr. Bertalan Meskó, MD, PhD, widely known as "The Medical Futurist," is a leading global expert on healthcare technology. He serves as the Director of The Medical Futurist Institute and is a Private Professor at Semmelweis University in Budapest, Hungary. With a background as a physician and a PhD in genomics, Dr. Meskó focuses on how tools like artificial intelligence, wearable devices, and robots can improve modern medicine. He has delivered hundreds of keynote presentations at top institutions like Harvard and Stanford. He is also a bestselling author who has been featured by major media outlets such as CNN, TIME, and National Geographic.

🎙️⚕️ABOUT HEALTH BIZ PODCAST
HealthBiz is a CareTalk podcast that delivers in-depth interviews on healthcare business, technology, and policy with entrepreneurs and CEOs. Host David E. Williams — president of the healthcare strategy consulting boutique Health Business Group — is also a board member, investor in private healthcare companies, and author of the Health Business Blog. Known for his strategic insights and sharp humor, David offers a refreshing break from the usual healthcare industry BS.

Need a Strategy Partner?
For over 20 years, Health Business Group has helped healthcare software companies, tech-enabled services businesses, life sciences companies, and payers make smarter strategic decisions. Led by podcast host David Williams, the firm advises clients on sharpening AI positioning, entering new segments, and building commercial strategies for value-based care. See examples of our work at healthbusinessgroup.com/

🩺 THIS EPISODE IS BROUGHT TO YOU BY:

PIM Health:
At PIM Health, we’re building real-time payment infrastructure where providers don’t wait weeks to get paid, patients don’t leave without knowing exactly what they owe, and employers stop flying blind on their own plan spend. AR burden, gone. Surprise bills, gone. Prior auth delays, gone. Denials and appeals, gone.

Learn what PIM Health is building here

GET IN TOUCH
Follow CareTalk on LinkedIn
Become a CareTalk sponsor
Guest appearance requests
Visit us on the web

Support the show

⚙️CareTalk:  Healthcare. Unfiltered. is produced by Grippi Media Digital Marketing Consulting.